Abstract:
:Understanding the link between neurobiology and cognition requires that neuroscience moves beyond mere structure-function correlations. An explicit systems perspective is needed in which putative mechanisms of how brain function is constrained by brain structure are mathematically formalized and made accessible for experimental investigation. Such a systems approach critically rests on a better understanding of brain connectivity in its various forms. Since 2002, frontier topics of connectivity and neural system analysis have been discussed in a multidisciplinary annual meeting, the Brain Connectivity Workshop (BCW), bringing together experimentalists and theorists from various fields. This article summarizes some of the main discussions at the two most recent workshops, 2006 at Sendai, Japan, and 2007 at Barcelona, Spain: (i) investigation of cortical micro- and macrocircuits, (ii) models of neural dynamics at multiple scales, (iii) analysis of "resting state" networks, and (iv) linking anatomical to functional connectivity. Finally, we outline some central challenges and research trajectories in computational systems neuroscience for the next years.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Stephan KE,Riera JJ,Deco G,Horwitz Bdoi
10.1016/j.neuroimage.2008.04.167subject
Has Abstractpub_date
2008-08-01 00:00:00pages
1-9issue
1eissn
1053-8119issn
1095-9572pii
S1053-8119(08)00503-Xjournal_volume
42pub_type
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