Systematic sequencing of mRNA from the Antarctic krill (Euphausia superba) and first tissue specific transcriptional signature.

abstract：BACKGROUND:Phytophthora species are oomycete plant pathogens with such major social and economic impact that genome sequences have been determined for Phytophthora infestans, P. sojae and P. ramorum. Pepsin-like aspartic proteinases (APs) are produced in a wide variety of species (from bacteria to humans) and contain c...

journal_title：BMC genomics

authors： Kay J,Meijer HJ,ten Have A,van Kan JA

更新日期：2011-05-20 00:00:00

abstract：BACKGROUND:The ultimate phenome of any organism is modulated by regulated transcription of many genes. Characterization of genetic makeup is thus crucial for understanding the molecular basis of phenotypic diversity, evolution and response to intra- and extra-cellular stimuli. Chickpea is the world's third most importa...

journal_title：BMC genomics

authors： Ashraf N,Ghai D,Barman P,Basu S,Gangisetty N,Mandal MK,Chakraborty N,Datta A,Chakraborty S

更新日期：2009-09-05 00:00:00

abstract：BACKGROUND:The cellular proteome and metabolome are underlying dynamic regulation allowing rapid adaptation to changes in the environment. System-wide analysis of these dynamics will provide novel insights into mechanisms of stress adaptation for higher photosynthetic organisms. We applied pulsed-SILAC labeling to a ph...

journal_title：BMC genomics

authors： Mastrobuoni G,Irgang S,Pietzke M,Assmus HE,Wenzel M,Schulze WX,Kempa S

更新日期：2012-05-31 00:00:00

abstract：BACKGROUND:Improvements in poultry production within the past 50 years have led to increased muscle yield and growth rate, which may be contributing to an increased rate and development of new muscle disorders in chickens. Previously reported muscle disorders and conditions are generally associated with poor meat quali...

journal_title：BMC genomics

authors： Mutryn MF,Brannick EM,Fu W,Lee WR,Abasht B

更新日期：2015-05-21 00:00:00

abstract：BACKGROUND:Stress responses provide valuable models for deciphering the transcriptional networks controlling the adaptation of the cell to its environment. We analyzed the transcriptome response of yeast to toxic concentrations of selenite. We used gene network mapping tools to identify functional pathways and transcri...

journal_title：BMC genomics

authors： Salin H,Fardeau V,Piccini E,Lelandais G,Tanty V,Lemoine S,Jacq C,Devaux F

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S. Typhi). In chronic carriers, the bacteria survive the harsh environment of the gallbladder by producing biofilm. The phenotype of S. Typhi biofilm cells is significantly different from t...

journal_title：BMC genomics

authors： Chin KCJ,Taylor TD,Hebrard M,Anbalagan K,Dashti MG,Phua KK

更新日期：2017-10-31 00:00:00

abstract：BACKGROUND:Transcriptome expression analysis in peanut to date has been limited to a relatively small set of genes and only recently has a significant number of ESTs been released into the public domain. Utilization of these ESTs for oligonucleotide microarrays provides a means to investigate large-scale transcript res...

journal_title：BMC genomics

authors： Payton P,Kottapalli KR,Rowland D,Faircloth W,Guo B,Burow M,Puppala N,Gallo M

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Alternative splicing (AS) is an important regulatory mechanism that greatly contributes to eukaryotic transcriptome diversity. A substantial amount of evidence has demonstrated that AS complexity is relevant to eukaryotic evolution, development, adaptation, and complexity. In this study, six teosinte and ten...

journal_title：BMC genomics

authors： Huang J,Gao Y,Jia H,Liu L,Zhang D,Zhang Z

更新日期：2015-05-08 00:00:00

abstract：BACKGROUND:Distichiasis, an ocular disorder in which aberrant cilia (eyelashes) grow from the opening of the Meibomian glands of the eyelid, has been reported in Friesian horses. These misplaced cilia can cause discomfort, chronic keratitis, and corneal ulceration, potentially impacting vision due to corneal fibrosis, ...

journal_title：BMC genomics

authors： Hisey EA,Hermans H,Lounsberry ZT,Avila F,Grahn RA,Knickelbein KE,Duward-Akhurst SA,McCue ME,Kalbfleisch TS,Lassaline ME,Back W,Bellone RR

更新日期：2020-11-30 00:00:00

abstract：BACKGROUND:Sub-optimal developmental diets often have adverse effects on long-term fitness and health. One hypothesis is that such effects are caused by mismatches between the developmental and adult environment, and may be mediated by persistent changes in gene expression. However, there are few experimental tests of ...

journal_title：BMC genomics

authors： May CM,Zwaan BJ

更新日期：2017-08-22 00:00:00

abstract：BACKGROUND:Drosophila melanogaster females show changes in behavior and physiology after mating that are thought to maximize the number of progeny resulting from the most recent copulation. Sperm and seminal fluid proteins induce post-mating changes in females, however, very little is known about the resulting gene exp...

journal_title：BMC genomics

authors： Dalton JE,Kacheria TS,Knott SR,Lebo MS,Nishitani A,Sanders LE,Stirling EJ,Winbush A,Arbeitman MN

更新日期：2010-10-06 00:00:00

abstract：BACKGROUND:The term pan-genome was proposed to denominate collections of genomic sequences jointly analyzed or used as a reference. The constant growth of genomic data intensifies development of data structures and algorithms to investigate pan-genomes efficiently. RESULTS:This work focuses on providing a tool for dis...

journal_title：BMC genomics

authors： Dziadkiewicz P,Dojer N

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:The preferred habitat of a given bacterium can provide a hint of which types of enzymes of potential industrial interest it might produce. These might include enzymes that are stable and active at very high or very low temperatures. Being able to accurately predict this based on a genomic sequence, would thu...

journal_title：BMC genomics

authors： Jensen DB,Vesth TC,Hallin PF,Pedersen AG,Ussery DW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Identifying causative mutations or genes through which quantitative trait loci (QTL) act has proven very difficult. Using information such as gene expression may help to identify genes and mutations underlying QTL. Our objective was to identify regions associated both with production traits or fertility and ...

journal_title：BMC genomics

authors： van den Berg I,Hayes BJ,Chamberlain AJ,Goddard ME

更新日期：2019-04-15 00:00:00

abstract：BACKGROUND:The sequential nature of gel-based marker systems entails low throughput and high costs per assay. Commonly used marker systems such as SSR and SNP are also dependent on sequence information. These limitations result in high cost per data point and significantly limit the capacity of breeding programs to obt...

journal_title：BMC genomics

authors： Mace ES,Xia L,Jordan DR,Halloran K,Parh DK,Huttner E,Wenzl P,Kilian A

更新日期：2008-01-22 00:00:00

abstract：BACKGROUND:Over the last decade, emerging research methods, such as comparative genomic analysis and phylogenetic study, have yielded new insights into genotypes and phenotypes of closely related bacterial strains. Several findings have revealed that genomic structural variations (SVs), including gene gain/loss, gene d...

journal_title：BMC genomics

authors： Jiang J,Gu J,Zhang L,Zhang C,Deng X,Dou T,Zhao G,Zhou Y

更新日期：2015-02-14 00:00:00

abstract：BACKGROUND:Precision medicine is a medical approach that takes into account individual genetic variability and often requires Next Generation Sequencing data in order to predict new treatments. Here we present GMIEC, Genomic Modules Identification et Characterization for genomics medicine, an application that is able t...

journal_title：BMC genomics

authors： Malagoli Tagliazucchi G,Taccioli C

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Litchi (Litchi chinensis Sonn.) is one of the most important fruit trees cultivated in tropical and subtropical areas. However, a lack of transcriptomic and genomic information hinders our understanding of the molecular mechanisms underlying fruit set and fruit development in litchi. Shading during early fru...

journal_title：BMC genomics

authors： Li C,Wang Y,Huang X,Li J,Wang H,Li J

更新日期：2013-08-14 00:00:00

abstract：BACKGROUND:Bacteroides thetaiotaomicron, a predominant member of the human gut microbiota, is characterized by its ability to utilize a wide variety of polysaccharides using the extensive saccharolytic machinery that is controlled by an expanded repertoire of transcription factors (TFs). The availability of genomic seq...

journal_title：BMC genomics

authors： Ravcheev DA,Godzik A,Osterman AL,Rodionov DA

更新日期：2013-12-12 00:00:00

abstract：BACKGROUND:Protein effectors of pathogenicity are instrumental in modulating host immunity and disease resistance. The powdery mildew pathogen of grasses Blumeria graminis causes one of the most important diseases of cereal crops. B. graminis is an obligate biotrophic pathogen and as such has an absolute requirement to...

journal_title：BMC genomics

authors： Pedersen C,Ver Loren van Themaat E,McGuffin LJ,Abbott JC,Burgis TA,Barton G,Bindschedler LV,Lu X,Maekawa T,Wessling R,Cramer R,Thordal-Christensen H,Panstruga R,Spanu PD

更新日期：2012-12-11 00:00:00

abstract：BACKGROUND:Phenylalanine ammonia lyase (PAL) is a key enzyme of the phenylpropanoid pathway that catalyzes the deamination of phenylalanine to trans-cinnamic acid, a precursor for the lignin and flavonoid biosynthetic pathways. To date, PAL genes have been less extensively studied in gymnosperms than in angiosperms. Ou...

journal_title：BMC genomics

authors： Bagal UR,Leebens-Mack JH,Lorenz WW,Dean JF

更新日期：2012-06-11 00:00:00

abstract：BACKGROUND:Although an adverse early-life environment has been linked to an increased risk of developing the metabolic syndrome, the molecular mechanisms underlying altered disease susceptibility as well as their relevance to humans are largely unknown. Importantly, emerging evidence suggests that these effects operate...

journal_title：BMC genomics

authors： Emerald BS,Chng K,Masuda S,Sloboda DM,Vickers MH,Kambadur R,Gluckman PD

更新日期：2011-10-16 00:00:00

abstract：BACKGROUND:Natural contamination and anthropogenic pollution of soils are likely to be major determinants of functioning and survival of keystone invertebrate taxa. Soil animals will have both evolutionary adaptation and genetically programmed responses to these toxic chemicals, but mechanistic understanding of such is...

journal_title：BMC genomics

authors： Owen J,Hedley BA,Svendsen C,Wren J,Jonker MJ,Hankard PK,Lister LJ,Stürzenbaum SR,Morgan AJ,Spurgeon DJ,Blaxter ML,Kille P

更新日期：2008-06-03 00:00:00

abstract：BACKGROUND:Identification of acute or recent hepatitis C virus (HCV) infections is important for detecting outbreaks and devising timely public health interventions for interruption of transmission. Epidemiological investigations and chemistry-based laboratory tests are 2 main approaches that are available for identifi...

journal_title：BMC genomics

authors： Lara J,Teka M,Khudyakov Y

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:The transcription factors peroxisome proliferator activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα) are key transcriptional regulators of adipocyte differentiation and function. We and others have previously shown that binding sites of these two transcription factors show a high degr...

journal_title：BMC genomics

authors： Schmidt SF,Jørgensen M,Chen Y,Nielsen R,Sandelin A,Mandrup S

更新日期：2011-03-16 00:00:00

abstract：:ᅟ: Upon publication of the original article [1], the authors had flagged that there was an error in Fig. 1c, as the key in this figure was displaying incorrectly. The colours had not displayed in the key in the final published article, and instead appear as plain white. ...

journal_title：BMC genomics

authors： Hohmann N,Koch MA

更新日期：2018-04-11 00:00:00

abstract：BACKGROUND:Despite substantial progress in mosquito genomic and genetic research, few cis-regulatory elements (CREs), DNA sequences that control gene expression, have been identified in mosquitoes or other non-model insects. Formaldehyde-assisted isolation of regulatory elements paired with DNA sequencing, FAIRE-seq, i...

journal_title：BMC genomics

authors： Behura SK,Sarro J,Li P,Mysore K,Severson DW,Emrich SJ,Duman-Scheel M

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:Because of the advent of high-throughput sequencing and the consequent reduction in the cost of sequencing, many organisms have been completely sequenced and most of their genes identified. It thus has become possible to represent whole genomes as ordered lists of gene identifiers and to study the rearrangem...

journal_title：BMC genomics

authors： Yue F,Zhang M,Tang J

更新日期：2008-09-16 00:00:00

abstract：BACKGROUND:Gymnosporangium spp. are fungal plant pathogens causing rust disease and most of them are known to infect two different host plants (heteroecious) with four spore stages (demicyclic). In the present study, we sequenced the transcriptome of G. japonicum teliospores on its host plant Juniperus chinensis and we...

journal_title：BMC genomics

authors： Tao SQ,Cao B,Morin E,Liang YM,Duplessis S

更新日期：2019-10-09 00:00:00

abstract：BACKGROUND:Transcription factor (TF) GAMYB, belonging to MYB family (named after the gene of the avian myeloblastosis virus) is a master gibberellin (GA)-induced regulatory protein that is crucial for development and germination of cereal grain and involved in anther formation. It activates many genes including high-mo...

journal_title：BMC genomics

authors： Bienias A,Góralska M,Masojć P,Milczarski P,Myśków B

更新日期：2020-08-24 00:00:00