The role of the paraventricular nucleus and pituitary gland in morphine analgesia.

Abstract:

:The authors investigated the analgesic effects of small morphine doses injected into the paraventricular nucleus (PVN) of normal rats and hypophysectomized (Hx) rats. An injection cannula was stereotactically inserted into the PVN or third ventricle. On the 5-7th postoperative day, morphine (7 micrograms) was injected and the pain threshold (paw lick latency: PLL) was measured using a hot plate analgesia meter (52.0 +/- 0.1 degrees C). PVN morphine injection caused significantly longer PLL than the control (physiological saline) in both normal and Hx rats. Ventricular morphine injection did not increase PLL over the control. PVN is a site of morphine action. The analgesia induced by PVN morphine injection was not affected by hypophysectomy, or induced by leaking of morphine into the third ventricle.

authors

Hashimoto M,Ohgami S,Yonemasu Y

doi

10.2176/nmc.31.629

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

629-34

issue

10

eissn

0470-8105

issn

1349-8029

pii

JST.Journalarchive/nmc1959/31.629

journal_volume

31

pub_type

杂志文章
  • Cervical (non-terminal) myelocystocele associated with rapidly progressive hydrocephalus and Chiari type II malformation--case report.

    abstract::An infant presented with a rare cervical (non-terminal) myelocystocele as a congenital skin-covered mass located in the midline of the posterior aspect of her neck. Magnetic resonance (MR) imaging and computed tomography showed a cystic mass filled with cerebrospinal fluid in the midline of the posterior aspect of the...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.50.174

    authors: Ochiai H,Kawano H,Miyaoka R,Nagano R,Kohno K,Nishiguchi T,Shimao Y

    更新日期:2010-01-01 00:00:00

  • Diagnosis of Intracranial Artery Dissection.

    abstract::Cerebral arterial dissection is defined as a hematoma in the wall of a cervical or an intracranial artery. Cerebral arterial dissection causes arterial stenosis, occlusion, and aneurysm, resulting in acute infarction and hemorrhage. Image analysis by such methods as conventional angiography, computed tomography, magne...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.ra.2015-0294

    authors: Kanoto M,Hosoya T

    更新日期:2016-09-15 00:00:00

  • Perimesencephalic nonaneurysmal subarachnoid hemorrhage with unilateral third cranial nerve palsy: two case reports.

    abstract::Perimesencephalic nonaneurysmal subarachnoid hemorrhage (PNSAH) is a benign form of subarachnoid hemorrhage and is usually not associated with any focal deficit. We describe two rare cases of PNSAH with unilateral third cranial nerve palsy. Both patients were treated conservatively. The outcomes of our two cases were ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.52.918

    authors: Sadamasa N,Sano N,Takeda N,Yoshida K,Narumi O,Chin M,Yamagata S

    更新日期:2012-01-01 00:00:00

  • Endoscopic endonasal approach to the middle cranial fossa through the cavernous sinus triangles: anatomical considerations.

    abstract::The lateral limit of endoscopic endonasal surgery has yet to be defined. The aim of this study was to investigate the lateral limit of endoscopic endonasal surgery at the level of the sphenoid sinus. Access from the sphenoid sinus to the middle cranial fossa through the cavernous sinus triangles was evaluated by cadav...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:

    authors: Komatsu F,Oda S,Shimoda M,Imai M,Shigematsu H,Komatsu M,Tschabitscher M,Matsumae M

    更新日期:2014-01-01 00:00:00

  • Cine-magnetic resonance imaging evaluation of communication between middle cranial fossa arachnoid cysts and cisterns.

    abstract::Cine-magnetic resonance (MR) imaging examinations were performed in 10 patients with middle cranial fossa arachnoid cysts to evaluate communication between the cysts and the normal cerebrospinal fluid (CSF) space. Eight of 10 patients were evaluated by time of flight cine-MR imaging, and two by phase contrast cine-MR ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.36.353

    authors: Eguchi T,Taoka T,Nikaido Y,Shiomi K,Fujimoto T,Otsuka H,Takeuchi H

    更新日期:1996-06-01 00:00:00

  • Effects of naloxone on prolactin-secreting pituitary adenomas.

    abstract::The investigators assessed the effects of the opioid antagonist naloxone on anterior pituitary hormone release in hyperprolactinemic females with pituitary microadenoma (n = 6) and macroadenoma (n = 7). In those with microadenoma, intravenous bolus injection of naloxone significantly increased serum luteinizing hormon...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.30.109

    authors: Shima K,Chigasaki H,Seki K

    更新日期:1990-02-01 00:00:00

  • Surgical decision for adult optic glioma based on [18F]fluorodeoxyglucose positron emission tomography study.

    abstract::A 51-year-old male presented with a 5-year history of progressive right exophthalmos and visual loss. Magnetic resonance imaging showed a right intraorbital lesion. [(18)F]fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) revealed high uptake in the tumor. No FDG was accumulated in the remaining optic t...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.46.500

    authors: Miyamoto J,Sasajima H,Owada K,Mineura K

    更新日期:2006-10-01 00:00:00

  • Pituitary adenoma invading the skull base--a strategy for skull base surgery.

    abstract::A strategy for surgical management, including the approach and preoperative evaluation, of pituitary adenoma invading the skull base is described. Preoperative evaluation requires a balloon occlusion test of the internal carotid artery (ICA) to determine tolerance to occlusion. Failure to tolerate occlusion indicates ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.34.686

    authors: Nakase H,Ohnishi H,Touho H,Takaoka M,Karasawa J,Kawaguchi M,Sakamoto T

    更新日期:1994-10-01 00:00:00

  • Giant aneurysm of the azygos anterior cerebral artery--case report.

    abstract::A 77-year-old female presented with a giant aneurysm of the azygos anterior cerebral artery (ACA) manifesting as acute onset of akinetic mutism caused by enlargement of the aneurysm resulting from rapid thrombus formation within the aneurysmal sac. Thrombus removal to obtain decompression of the aneurysmal bulk and te...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.40.472

    authors: Kanemoto Y,Tanaka Y,Nonaka M,Hironaka Y

    更新日期:2000-09-01 00:00:00

  • Presentation with recurrent intractable headache: a patient with moyamoya syndrome--case report.

    abstract::This clinical case report represents an interesting manifestation of a neurovascular condition that can be easily overlooked by the practicing healthcare provider. In the United States, a Hispanic patient of non-Asian descent presented with atypical symptoms of intractable headache and nausea with no evidence of neuro...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.cr2012-0134

    authors: Diaz UJ,Cabán-Martinez AJ,Halder GE

    更新日期:2014-01-01 00:00:00

  • Suprachiasmal carotid-ophthalmic artery aneurysm--report of two cases.

    abstract::Two rare suprachiasmal carotid-ophthalmic artery aneurysms, one large and one giant, were discovered incidentally. The patients had no visual disturbances. Angiography showed superomedial projection of the sac. The aneurysms were clipped via an ipsilateral pterional approach. A suprachiasmal carotid-ophthalmic artery ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.32.952

    authors: Diraz A,Kobayashi S,Okudera H,Nakagawa F,Tsuji T,Toba Y

    更新日期:1992-12-01 00:00:00

  • Cerebral sinus thrombosis in patient with ulcerative colitis--case report.

    abstract::Left transverse sinus thrombosis developed in a 27-year-old male with ulcerative colitis. The diagnosis was based on cerebral angiography and magnetic resonance (MR) imaging, the latter of which clearly delineated the intraluminal thrombus. Serial MR images demonstrated thrombus organization. The use of this method in...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.32.232

    authors: Moriyama E,Shinohara C,Tokunaga K,Kamitani M,Norikane H,Matsumoto Y,Motoki M

    更新日期:1992-04-01 00:00:00

  • Bone window computed tomography for detection of dural defect associated with cervical ossified posterior longitudinal ligament.

    abstract::Anterior decompression of a cervical ossified posterior longitudinal ligament (OPLL) which involves the dura mater occasionally results in a postoperative cerebrospinal fluid fistula. Bone window computed tomography (CT) was carried out to detect dural defects in 21 patients with cervical OPLL. Twelve of 21 patients h...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.37.173

    authors: Hida K,Iwasaki Y,Koyanagi I,Abe H

    更新日期:1997-02-01 00:00:00

  • Combination chemotherapy with cisplatin and etoposide for hematogenous spinal metastasis of intracranial germinoma--case report.

    abstract::A 24-year-old male presented with a metastatic germinoma in the thoracic vertebra 7 years after irradiation of a pineal germinoma. Combination chemotherapy with cisplatin and etoposide was highly effective. No recurrence has appeared in the 2 years since chemotherapy. ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.33.28

    authors: Itoyama Y,Kochi M,Yamashiro S,Yoshizato K,Kuratsu J,Ushio Y

    更新日期:1993-01-01 00:00:00

  • Coexistence of intracranial and spinal meningiomas--report of two cases.

    abstract::The authors report two rare cases of multiple meningiomas in both the intracranial and spinal regions. A 64-year-old female presented with a right sphenoidal ridge meningioma and a cervical extramedullary meningioma. Tumor histology was transitional and vacuolated types, respectively. The tumors were removed successfu...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.31.720

    authors: Kannuki S,Soga T,Hondo H,Matsumoto K,Takada K,Makino A

    更新日期:1991-11-01 00:00:00

  • Cerebral ischemia promotes rich pseudopalisading necrosis in the rat c6 glioblastoma model.

    abstract::The effect of hypoxia on glioma growth including pathological changes was investigated in an experimental model of brain ischemia in the rat C6 glioma model. C6 glioma cells were inoculated into the subcortex of adult Wistar rats. Focal cerebral ischemia near the implanted glioma area was induced by permanent middle c...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.49.294

    authors: Mamun MH,Kamitani H,Kinoshita Y,Tabuchi S,Wasita B,Watanabe T

    更新日期:2009-07-01 00:00:00

  • Optic nerve evoked potentials elicited by electrical stimulation.

    abstract::This study investigated whether the optic nerve evoked potential (ONEP) elicited by electrical stimulation of the optic nerve can serve as a reliable intraoperative indicator of visual function. In the experimental study, two silver-ball stimulating electrodes were placed on the dog optic nerve adjacent to the apex of...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.45.349

    authors: Kikuchi Y,Sasaki T,Matsumoto M,Oikawa T,Itakura T,Kodama N

    更新日期:2005-07-01 00:00:00

  • Endovascular treatment of asymptomatic cerebral aneurysms: anatomic and technical factors related to ischemic events and coil stabilization.

    abstract::The present study assessed the safety and efficacy of embolization using Guglielmi detachable coils (GDCs) in 100 asymptomatic cerebral aneurysms classified as sidewall (70) or terminal (30) aneurysms according to the parent artery (68 small aneurysms with a small neck, 21 small aneurysms with a wide neck, and 11 larg...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.44.456

    authors: Soeda A,Sakai N,Sakai H,Iihara K,Nagata I

    更新日期:2004-09-01 00:00:00

  • Progression of intracranial meningioma during luteinizing hormone-releasing hormone agonist treatment for prostate cancer: case report.

    abstract::The authors describe a male patient who developed a large intracranial meningioma during the hormone therapy for pre-existing prostate cancer. A 70-year-old man received a brain check-up, and no intracranial abnormality was detected. Five months later, prostate cancer was diagnosed, and he underwent prostatectomy. Leu...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.cr2012-0417

    authors: Anda T,Honda M,Ishihara T,Kamei T

    更新日期:2014-01-01 00:00:00

  • Simultaneous bilateral vertebral artery occlusion in the lower cervical spine manifesting as bow hunter's syndrome.

    abstract::A 59-year-old male had suffered near-syncopal episodes for more than one year that occurred immediately on turning his head to the left. Cerebral magnetic resonance (MR) imaging did not detect any contributing lesions with well-developed posterior communicating arteries. Dynamic radiography of the cervical spine showe...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.48.90

    authors: Tsutsumi S,Ito M,Yasumoto Y

    更新日期:2008-02-01 00:00:00

  • Subarachnoid Hemorrhage from Vertebral Arteriovenous Fistula without Perimedullary Drainage: Rare Stroke Hemorrhagic Event in a Patient of Neurofibromatosis Type 1.

    abstract::Vertebral arteriovenous fistula (VAVF), which can cause subarachnoid hemorrhage (SAH) when having a perimedurally drainage, has been reported as a rare vascular abnormality in patients with neurofibromatosis type 1 (NF-1). In addition, extracranial vertebral aneurysm (EVAn) coexisting with VAVF and NF-1 is considered ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.cr.2017-0241

    authors: Maki Y,Ishibashi R,Fukuda H,Kobayashi M,Chin M,Yamagata S

    更新日期:2018-04-15 00:00:00

  • Germinoma of the medulla oblongata--case report.

    abstract::A 32-year-old female presented with medulla oblongata germinoma manifesting as numbness in the extremities. Computed tomography demonstrated a mass in the medulla oblongata expanding into the fourth ventricle. The tumor was partially removed. Immunohistochemical staining of the tumor specimen demonstrated large epithe...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章,评审

    doi:10.2176/nmc.34.291

    authors: Sugiyama K,Uozumi T,Goishi J,Sogabe T,Arita K,Maeda H,Ikawa F

    更新日期:1994-05-01 00:00:00

  • Cryptococcal meningoencephalitis presenting with an unusual magnetic resonance imaging appearance--case report.

    abstract::A 61-year-old female with a past history of gastric cancer presented with altered mental status, a few seizures, and low-grade fever. Lumbar puncture revealed elevated cerebrospinal fluid (CSF) pressure, lymphocytic pleocytosis, elevated protein level, remarkably decreased glucose level, and presence of cryptococcal a...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.41.517

    authors: Kuwahara S,Kawada M,Uga S

    更新日期:2001-10-01 00:00:00

  • Sponge-induced granuloma ("gauzoma") as a complication of posterior lumbar surgery.

    abstract::A 45-year-old woman presented with complaints of low back pain and sciatica on the left persisting for 2 years. She had undergone left hemilaminectomy and discectomy for L4-5 intervertebral disc herniation at another medical center. Spinal computed tomography and magnetic resonance (MR) imaging revealed a mass lesion ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.45.209

    authors: Turgut M,Akyüz O,Ozsunar Y,Kacar F

    更新日期:2005-04-01 00:00:00

  • Real-time Imaging of an Experimental Intracranial Aneurysm in Rats.

    abstract::Subarachnoid hemorrhage due to rupture of a pre-existing intracranial aneurysm has quite a poor outcome in spite of intensive medical care. Hemodynamic stress loaded on intracranial arterial walls is considered as a trigger and a regulator of formation and progression of the disease, but how intracranial arterial wall...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.oa.2018-0197

    authors: Miyata H,Shimizu K,Koseki H,Abekura Y,Kataoka H,Miyamoto S,Nozaki K,Narumiya S,Aoki T

    更新日期:2019-01-15 00:00:00

  • Morphological effects of tumor necrosis factor-alpha on the blood vessels in rat experimental brain tumors.

    abstract::The morphological changes in the vascular endothelium caused by the administration of tumor necrosis factor-alpha (TNF-alpha) were studied in an experimental model of rat brain tumors. Wistar rats bearing implanted C6 glioma received human natural-type TNF-alpha (1.7 x 10(5) U/m2) through the carotid artery and were s...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.36.423

    authors: Isaka T,Yoshimine T,Maruno M,Hayakawa T

    更新日期:1996-07-01 00:00:00

  • Endovascular coiling as the first treatment strategy for ruptured pericallosal artery aneurysms: results, complications, and follow up.

    abstract::We apply endovascular coiling as the first treatment option for ruptured pericallosal artery aneurysms. We conducted a retrospective analysis of the clinical and radiological outcomes of this treatment strategy and morphological factors associated with the success of endovascular coiling, to assess the safety and feas...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.53.409

    authors: Yamazaki T,Sonobe M,Kato N,Kasuya H,Ikeda G,Nakamura K,Ito Y,Tsuruta W,Nakai Y,Matsumura A

    更新日期:2013-01-01 00:00:00

  • Anaplastic ganglioglioma of the cerebellopontine angle. Case report.

    abstract::A 64-year-old woman presented with a rare anaplastic ganglioglioma in the right cerebellopontine angle manifesting as dizziness persisting for 2 weeks. Preoperative magnetic resonance (MR) imaging revealed a partially enhanced cystic lesion of the right cerebellopontine angle. The tumor was subtotally removed through ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.45.591

    authors: Matsuzaki K,Uno M,Kageji T,Hirose T,Nagahiro S

    更新日期:2005-11-01 00:00:00

  • Unusual location of intracranial vagus neurinoma--case report.

    abstract::A 55-year-old male presented with hearing disturbance and tinnitus in the left ear. Computed tomography (CT) and magnetic resonance imaging demonstrated a well-defined, homogeneously enhanced mass in the left cerebellomedullary cistern without extension close to the jugular foramen. A three-dimensional image reconstru...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.35.667

    authors: Kamiguchi H,Ohira T,Kobayashi M,Ogino M,Shiobara R,Toya S

    更新日期:1995-09-01 00:00:00

  • Central neurocytoma presenting with massive hemorrhage leading to coma--case report.

    abstract::A 21-year-old man presented with a hemorrhagic central neurocytoma manifesting as acute onset of disturbance of consciousness and right hemiparesis. Computed tomography (CT) demonstrated a tumor in the left lateral ventricle during the course of evaluation for mental alteration 12 days before onset, but the tumor was ...

    journal_title:Neurologia medico-chirurgica

    pub_type: 杂志文章

    doi:10.2176/nmc.50.139

    authors: Terakawa Y,Tsuruno T,Ishibashi K,Okada Y,Shimotake K,Murata T

    更新日期:2010-01-01 00:00:00