Abstract:
:We followed prospectively 834 consecutive patients (70% inpatients), evaluated for suspected pulmonary embolism, for a median time of 2.1 years (range, 0-4.8 yr), and compared the survival rates in patients with proven pulmonary embolism (n=320) with those without (n=514). In multivariate analysis, we modeled the probability of surviving in patients with pulmonary embolism as a function of the extent of pulmonary vascular obstruction at baseline. Among patients with pulmonary embolism, a scintigraphic follow-up was pursued to assess the restoration of pulmonary perfusion over a 1-year period. We found that massive pulmonary embolism (vascular obstruction>or=50%) is a risk factor for mortality within the first few days after onset but, subsequently, has no significant effect on survival. The adjusted risk of death in patients with massive pulmonary embolism was 8-fold higher than in patients without embolism within the first day after the incident event. By contrast, the adjusted risk of death for patients with minor or moderate pulmonary embolism (vascular obstruction<50%) was no higher than in patients without embolism at any time after onset. Most of the patients who survived a year after pulmonary embolism showed a nearly complete restoration of pulmonary perfusion with a considerable improvement in arterial oxygenation. Four (1%) of the 320 patients with pulmonary embolism at presentation developed chronic thromboembolic pulmonary hypertension. These patients featured persistent large perfusion defects in sequential lung scans. Pulmonary embolism with vascular obstruction>or=50% is a strong, independent predictor of reduced short-term survival. This underscores the need for a prompt diagnosis of the disease. Monitoring the resolution of pulmonary embolism by lung scanning may prove useful in identifying patients with persistent perfusion abnormalities who may be at risk of chronic thromboembolic pulmonary hypertension.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Miniati M,Monti S,Bottai M,Scoscia E,Bauleo C,Tonelli L,Dainelli A,Giuntini Cdoi
10.1097/01.md.0000236952.87590.c8subject
Has Abstractpub_date
2006-09-01 00:00:00pages
253-262issue
5eissn
0025-7974issn
1536-5964pii
00005792-200609000-00001journal_volume
85pub_type
杂志文章相关文献
MEDICINE文献大全abstract:RATIONALE:Retinal cavernous hemangioma is a rare congenital vascular malformation with typical fundus changes. Optical coherence tomography angiography (OCTA), which is in rise in the recent years, is a rapid and noninvasive technology to assist in obtaining information regarding the blood flow changes in the fundus le...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009940
更新日期:2018-02-01 00:00:00
abstract::Early risk stratification is crucial for appropriate management using invasive strategies in non-ST elevation myocardial infarction (NSTEMI), and electrocardiography (ECG) has been widely used for risk stratification. However, ECG findings in NSTEMI vary, and there is a need to define the clinical characteristics and ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004862
更新日期:2016-09-01 00:00:00
abstract:RATIONALE:Priapism is a common urologic emergency, but high-flow penile priapism (HFP) caused by trauma is very rare. Therefore, HFP diagnosis and treatment are still not standardized. PATIENT CONCERNS:A 29-year-old man was admitted to the urology department of our hospital on August 01, 2019, due to "persistent penil...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022618
更新日期:2020-10-09 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000001654.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000479947.63919.bc
更新日期:2016-01-22 00:00:00
abstract:BACKGROUND:Chronic pelvic inflammation disease (PID) is a difficult-to-treat gynecological disorder with complex etiologies. Acupuncture has been applied widely for treating chronic pelvic inflammation or chronic pelvic pain symptoms in China. The aim of this review is to undertake a systematic review to estimate the e...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010225
更新日期:2018-03-01 00:00:00
abstract::Guidelines for patients with subarachnoid hemorrhage (SAH) management and several grading systems or prognostic indices have been used not only to improve the quality of care but to predict also the outcome of these patients. Among them, the gold standards Fisher radiological grading scale, Hunt-Hess and the World Fed...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012769
更新日期:2018-10-01 00:00:00
abstract:INTRODUCTION:Expiratory central airway collapse is defined by excessive inward bulging of either tracheobronchial posterior membrane or cartilage. The former is called excessive dynamic airway collapse (EDAC), and the latter, depending on the site of collapse, tracheomalacia, bronchomalacia or tracheobronchomalacia. Du...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022449
更新日期:2020-10-16 00:00:00
abstract:BACKGROUND:This pilot study aimed to evaluate the feasibility effectiveness and safety of transcutaneous electrical nerve stimulation (TENS) for patients with acute tinnitus. METHODS:A total of 46 eligible patients with acute tinnitus were entered and included in this randomized controlled trial. All the included pati...
journal_title:Medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MD.0000000000013793
更新日期:2019-01-01 00:00:00
abstract::Uremic pruritus is common and bothersome in patients receiving either peritoneal dialysis (PD) or hemodialysis (HD). To date, the preferred dialysis modality regarding the alleviation of uremic pruritus remains controversial. We conducted this cross-sectional study to compare the prevalence, intensity, and characteris...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002935
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Primary mucoepidermoid carcinoma (MEC) of the esophagus is a rare type of malignant neoplasm. Its morphology resembles that of MEC of the salivary glands. It is characterized by a diffuse mixture of squamous and mucus-secreting glandular carcinoma cells. Due to the low incidence of esophageal MEC, the biologi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011165
更新日期:2018-06-01 00:00:00
abstract::This study was conducted to estimate the 25-hydroxyvitamin D (25 (OH)D) levels and explore factors related to vitamin D deficiency/insufficiency. This was a multicenter, hospital-based, cross-sectional observational study. Children admitted to hospitals for health examination were included for vitamin D measurement an...
journal_title:Medicine
pub_type: 杂志文章,多中心研究
doi:10.1097/MD.0000000000022463
更新日期:2020-10-30 00:00:00
abstract::The free antiretroviral therapy (ART) program in India has scaled up to register second largest number of people living with HIV/AIDS across the globe. To assess the effectiveness of current first-line regimen we estimated virological suppression on completion of 1 year of ART. The study describes the correlates of vi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004886
更新日期:2016-09-01 00:00:00
abstract:RATIONALE:Anaphylaxis is a very rare event in pregnancy, triggering maternal hypotension leading to intrapartum hypoxic-ischemic encephalopathy in infant. Furthermore, cesarean sections are performed at a high rate in anaphylactic pregnant women. PATIENT CONCERNS:A 34-year-old pregnant woman presented with maternal an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012351
更新日期:2018-09-01 00:00:00
abstract::Recent studies have investigated the most efficacious dose of intravenous tissue plasminogen activator (IV-tPA) for acute ischemic stroke (AIS) patients. There remains no definitive consensus concerning the superior efficacious IV-tPA dose (standard- vs. low-dose), prompting us to perform a meta-analysis comparing the...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000002412
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Prostate cancer (PCa) is one of the leading causes of cancer-related death. In the present research, we adopted a comprehensive bioinformatics method to identify some biomarkers associated with the tumor progression and prognosis of PCa. METHODS:Differentially expressed genes (DEGs) analysis and weighted ge...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019628
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Pancreatic cancer (PC) remains difficult to treat, despite the recent advances in various anticancer therapies. Immuno-inflammatory response is considered to be a major risk factor for the development of PC in addition to a combination of genetic background and environmental factors. Although patients with P...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000005541
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:DNA methylation is the earliest and most studied epigenetic modification in cancer. The literature reported that the abnormal methylation level of multiple genes was associated with poor prognosis in ovarian cancer. However, due to a small sample size, the results reported in the literature vary widely. In th...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000014588
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Tall cell variant papillary thyroid carcinoma (TCPTC) is reportedly associated with aggressive clinicopathological parameters and poor outcomes; however, the molecular mechanisms underlying TCPTC remain poorly understood. METHODS:The gene mutation types and mRNA expression profiles of patients with TCPTC we...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000013802
更新日期:2018-12-01 00:00:00
abstract::Total hip arthroplasty (THA) for high congenital hip dislocation (CHD) is technically demanding. The purpose of this retrospective study was to evaluate the results of cementless THA combined with extended sliding trochanteric osteotomy. We also assessed whether chronic low back pain was relieved after surgery.The stu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006581
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Malignant glioma is the most common primary malignant brain tumor that displays high vascularity, making vascular endothelial growth factor receptors become promising targets. This study was conducted to evaluate the efficacy and safety of apatinib, a new potent oral small-molecule tyrosine kinase inhibitor ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009053
更新日期:2017-12-01 00:00:00
abstract::Thyrotoxic periodic paralysis (TPP) is characterized by the presence of muscle paralysis, hypokalemia, and hyperthyroidism. We report the case of a young man with paralysis of the lower extremities, severe hypokalemia, and concurrent hyperthyroidism. TPP was suspected; therefore, treatment consisting of judicious pota...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001689
更新日期:2015-09-01 00:00:00
abstract::Research and management of XLH have concentrated on the disease in childhood, and the natural history and morbidity of XLH in adult life are thus poorly understood. We have studied 22 adults (6 men) with XLH to clarify these aspects of this most common inherited form of rickets and osteomalacia. Most study participant...
journal_title:Medicine
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract::This study was aimed to evaluate whether silver-containing dressings were superior to other types of dressings in the treatment of venous leg ulcers (VLU) and their specific advantages.Eight databases (Cochrane Library, PubMed, Web of Science, Ovid-Medline, Wanfang, VIP, China Biology Medicine, and China National Know...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000022164
更新日期:2020-09-11 00:00:00
abstract::To use a new method to estimate the prevalence of drug addicts in Xichang for the first time and to suggest that Chinese Center for Disease Control and Prevention should strengthen surveillance and intervention for them.The Capture-Mark-Recapture (CMR) method of 3 correlated sources under the simple random sampling an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013919
更新日期:2019-01-01 00:00:00
abstract::We conducted the present study to determine whether subclinical macrovascular atherosclerotic disease was present in patients with ankylosing spondylitis (AS) without clinical history of cardiovascular disease. We also sought to establish whether demographic or clinical features of the disease may influence the develo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0b013e3181c10773
更新日期:2009-11-01 00:00:00
abstract::This retrospective study evaluated the effect of neuromuscular electrical stimulation (NMES) for the treatment of endometriosis-associated pain (EAP).A total of 154 patients with EAP were included and were divided into 2 groups in this retrospective study. Eighty-three patients were assigned a treatment group, and und...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011266
更新日期:2018-06-01 00:00:00
abstract:RATIONALE:Malakoplakia is a rare disease characterized by the presence of nongranulomatous macrophage infiltration. In most cases, it affects the urinary tract. Malakoplakia can cause acute kidney injury when it is localized in the kidneys. PATIENT CONCERNS:Here, we report the case of a 65-year-old female patient with...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012090
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:Rosacea is an irritating disease that affects patients' health and life quality. The current treatments for rosacea have limited efficacy and are generally not satisfying most patients. This report presents a patient diagnosed with rosacea who was treated with acupuncture to a satisfactory effect. Laser Doppl...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011931
更新日期:2018-08-01 00:00:00
abstract:RATIONALE:Hepatoid adenocarcinoma of lung (HAL) is a rare malignant tumor, which can be defined as a primary alpha-fetoprotein (AFP)-producing lung carcinoma. The majority of hepatoid adenocarcinoma (HAC) expressed AFP in tumor cells, but AFP expression is not required for its diagnosis according to the modified diagno...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000015053
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Pericardial infection caused by Acinetobacter baumannii is rare, particularly that of carbapenem-resistant A baumannii (CRAB). CASE PRESENTATION:We describe a rare case of purulent pericarditis due to CRAB in a 76-year-old man with acute myocardial infarction and acute kidney injury. The man was admitted to...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017034
更新日期:2019-09-01 00:00:00