Malakoplakia as a cause of severe hypercalcemia through ectopic 25-hydroxyvitamin D3 1-alpha-hydroxylase expression: A case report.

Abstract:

RATIONALE:Malakoplakia is a rare disease characterized by the presence of nongranulomatous macrophage infiltration. In most cases, it affects the urinary tract. Malakoplakia can cause acute kidney injury when it is localized in the kidneys. PATIENT CONCERNS:Here, we report the case of a 65-year-old female patient with renal malakoplakia responsible for hypercalcemia. During her initial assessment, she was also diagnosed 25-OH vitamin D insufficiency, for which she was prescribed oral cholecalciferol. Three months later, she developed severe hypercalcemia with normal 25-OH vitamin D and parathyroid hormone levels and high 1,25-dihydroxyvitamin D levels. DIAGNOSES:After a superimposed granulomatous disease was excluded, malakoplakia cells were suspected to be responsible for the abnormal 25-hydroxyvitamin D3 1-alpha-hydroxylase activity, which was confirmed by immunohistochemistry. INTERVENTIONS:Cholecalciferol was stopped, the patient was rehydrated with intravenous physiological saline, and prednisone was initiated to decrease the enzyme activity. OUTCOMES:Six months later, she displayed normal serum calcium, 25-OH vitamin D and 1,25-dihydroxyvitamin D levels. LESSONS:This case illustrates that malakoplakia may exhibit ectopic 25-hydroxyvitamin D3 1-alpha-hydroxylase activity and cause severe hypercalcemia upon vitamin D supplementation. Therefore, such supplementation should not be given in malakoplakia patients without an actual deficiency and requires careful monitoring of serum calcium.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Chemouny JM,Sannier A,Hanouna G,Champion L,Vrtovsnik F,Daugas E

doi

10.1097/MD.0000000000012090

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

e12090

issue

40

eissn

0025-7974

issn

1536-5964

pii

00005792-201810050-00004

journal_volume

97

pub_type

杂志文章

相关文献

MEDICINE文献大全
  • New universal primers for genotyping and resistance detection of low HBV DNA levels.

    abstract::HBV (hepatitis B virus) genotyping is important in determining the clinical manifestation of disease and treatment response, particularly, in patients with low viral loads. Also, sensitive detection of HBV antiviral drug resistance mutations is essential for monitoring therapy response.Asensitive direct sequencing met...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004618

    authors: Tong Y,Liu B,Liu H,Zheng H,Gu J,Liu H,Lin M,Ding Y,Song C,Li Y

    更新日期:2016-08-01 00:00:00

  • A Pilot Study of MicroRNAs Expression Profile in Serum and HBsAg Particles: Predictors of Therapeutic Vaccine Efficacy in Chronic Hepatitis B Patients.

    abstract::Chronic hepatitis B (CHB) remains a global health problem. Therapeutic vaccination has been successfully employed to treat a subpopulation of CHB patients. Personalized treatment can not only improve therapeutic efficacy, but also decrease the cost of medical care. Since microRNAs (miRNAs) are highly conserved and are...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000002511

    authors: Wang W,Li J,Zhang X,Wen Y,Wang XY,Yuan Z

    更新日期:2016-01-01 00:00:00

  • Cerebellar pilocytic astrocytomas with spontaneous intratumoral hemorrhage in the elderly: A case report and review of the literature.

    abstract:RATIONALE:Pilocytic astrocytoma (PA) is the most common pediatric central nervous system glial tumor. Adult occurrence is rare, especially in elderly adults. How to manage the pilocytic astrocytoma with spontaneous intratumoral hemorrhage in the elderly is still unfamiliar with clinician. PATIENT CONCERNS:Reports of t...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000011329

    authors: Sun S,Zhou H,Ding ZZ,Shi H

    更新日期:2018-08-01 00:00:00

  • Primary anorectal malignant melanoma: A case report.

    abstract:INTRODUCTION:Anorectal malignant melanoma (AMM) is a rare and aggressive malignance with poor prognosis, yet no consensus of treatment exists to date. Abdominoperineal resection surgery (APR) is the standard treatment of anorectal malignant melanoma, capable of controlling lymphatic spread and obtaining a large negativ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019028

    authors: Xu X,Ge T,Wang G

    更新日期:2020-01-01 00:00:00

  • Association between miR-27a rs895819 polymorphism and breast cancer susceptibility: Evidence based on 6118 cases and 7042 controls.

    abstract:BACKGROUND:Polymorphism in miR-27a rs895819 has been associated with breast cancer (BC) risk, but studies have reported inconsistent results. This meta-analysis investigated the possible association between miR-27a rs895819 polymorphism and BC risk. METHODS:PubMed, EMBASE, Google Scholar, and the Chinese National Know...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023834

    authors: Liu Y,Gui YF,Liao WY,Zhang YQ,Zhang XB,Huang YP,Wu FM,Huang Z,Lu YF

    更新日期:2021-01-15 00:00:00

  • Erratum: The interplay between hospital and surgeon factors and the use of sentinel lymph node biopsy for breast cancer: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000004392.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/01.md.0000505544.39976.a7

    authors:

    更新日期:2016-10-21 00:00:00

  • Gallbladder bleeding-related severe gastrointestinal bleeding and shock in a case with end-stage renal disease: A case report.

    abstract::Gallbladder (GB) bleeding is very rare and it is caused by cystic artery aneurysm and rupture, or GB wall rupture. For GB rupture, the typical findings are positive Murphy's sign and jaundice. GB bleeding mostly presented as hemobilia. This is the first case presented with severe GI bleeding because of GB rupture-rela...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000003870

    authors: Tsai JL,Tsai SF

    更新日期:2016-06-01 00:00:00

  • Efficacy and safety of Xiaofeng powder (xiao feng san) in treating urticaria: A protocol for a systematic review and meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Urticaria is a common skin disease that has a high impact on a patient's daily life. Xiaofeng powder (XFP) is one of the most commonly used Chinese herbal formula in China for urticaria. However, due to the lack of systematic evaluations, its clinical efficacy remains controversial. This meta-analysis was pe...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000013039

    authors: Chen G,Zhao J,Chen T,Zhang Z,Huang C,Xu Z,Xu H

    更新日期:2018-11-01 00:00:00

  • A research on the protein expression of p53, p16, and MDM2 in endometriosis.

    abstract::This study aims to examine the expression of p53, p16, and murine double minute 2 (MDM2) protein in normal endometrium and endometriosis, in order to discuss the role of p53, p16, and MDM2 protein and apoptosis in the pathogenesis and development of endometriosis, and provide a theoretical basis for clinical diagnosis...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014776

    authors: Sang L,Fang QJ,Zhao XB

    更新日期:2019-04-01 00:00:00

  • Contradictions between DAPT and PRECISE-DAPT scores with the severity of coronary lesion in acute coronary syndrome.

    abstract::This study aimed to identify the correlation of contradiction between DAPT score and PRECISE-DAPT score with the severity of coronary lesion in acute coronary syndromes (ACS).In total, 458 patients with ACS after a percutaneous coronary intervention (PCI) who had tolerated 1-year uneventful dual antiplatelet therapy (...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019699

    authors: Bi S,Zhao Y,Peng Q,Liu W,Zhang G,Zhang C

    更新日期:2020-04-01 00:00:00

  • Risk factors of invasive candidiasis in critical cancer patients after various gastrointestinal surgeries: A 4-year retrospective study.

    abstract::For early diagnosis and treatment of invasive candidiasis (IC), the well-known risk factors may not apply in the intensive care unit (ICU). This retrospective study identified the risk factors predicting IC and candidemia in cancer patients under intensive care after gastrointestinal surgery.Enrolled were 229 cancer p...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000017704

    authors: Xia R,Wang D

    更新日期:2019-11-01 00:00:00

  • The first case report of a large deletion of the BRCA1 gene in Croatia: A case report.

    abstract:RATIONALE:Breast cancer is one of the most common cancers in women, and it is the leading cause of cancer related deaths in Croatia. BRCA1 and BRCA2 gene mutations are the most common cause of hereditary breast cancer. PATIENT CONCERNS:In this report we describe a Croatian patient with no apparent family history of ca...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008667

    authors: Musani V,Sušac I,Ozretić P,Eljuga D,Levanat S

    更新日期:2017-12-01 00:00:00

  • The AESOP (adenopathy and extensive skin patch overlying a plasmacytoma) syndrome: report of 4 cases of a new syndrome revealing POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes) syndrome at a curable stage.

    abstract::We describe an easily recognizable and previously not individualized clinical syndrome that can reveal solitary plasmacytoma of bone. We report 4 patients with a slowly extending violaceous skin patch overlying a solitary plasmacytoma of bone, associated with enlarged regional lymph nodes. Biopsies of the cutaneous le...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-200301000-00005

    authors: Lipsker D,Rondeau M,Massard G,Grosshans E

    更新日期:2003-01-01 00:00:00

  • Different patterns in mental rotation of facial expressions in complex regional pain syndrome patients.

    abstract::Although facial pain expressions are considered to be the most visible pain behaviors, it is known that the association between pain intensity and facial pain expression is weak for chronic pain. The authors hypothesized that the facial pain expressiveness was altered in chronic pain and investigated it with a mental ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007990

    authors: Lee WJ,Choi SH,Jang JH,Moon JY,Kim YC,Noh E,Shin JE,Shin H,Kang DH

    更新日期:2017-09-01 00:00:00

  • Efficacy of oral ketamine compared to midazolam for sedation of children undergoing laceration repair: A double-blind, randomized, controlled trial.

    abstract:OBJECTIVE:To assess the efficacy of oral ketamine versus oral midazolam for sedation during laceration repair at a pediatric emergency department. METHODS:Children between 1 and 10 years requiring laceration repair were randomly assigned to 2 groups, treated either with oral midazolam (0.7 mg/kg) or with oral ketamine...

    journal_title:Medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MD.0000000000003984

    authors: Rubinstein O,Barkan S,Breitbart R,Berkovitch S,Toledano M,Weiser G,Karadi N,Nassi A,Kozer E

    更新日期:2016-06-01 00:00:00

  • Postoperative changes of liver enzymes can distinguish between biliary stricture and graft rejection after living donor liver transplantation: A longitudinal study.

    abstract::There is no known useful clinical parameter that can specifically predict a biliary stricture and differentiate it from other related complications after living donor liver transplantations (LDLT). The aims of this study were to determine whether the changes of liver enzymes can predict postoperative biliary stricture...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006892

    authors: Woo YS,Lee KH,Lee KT,Lee JK,Kim JM,Kwon CHD,Joh JW,Kang D,Cho J

    更新日期:2017-10-01 00:00:00

  • The effect of platelet-rich plasma on reducing blood loss after total knee arthroplasty: A systematic review and meta-analysis.

    abstract:BACKGROUND:Efficacy and safety of platelet-rich plasma (PRP) compared with control for preventing postoperative bleeding after total knee arthroplasty (TKA) is controversial. We performed a meta-analysis of randomized controlled trials (RCTs) to determine whether PRP might reduce blood loss and improve function followi...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000007262

    authors: Ma J,Sun J,Guo W,Li Z,Wang B,Wang W

    更新日期:2017-06-01 00:00:00

  • Omalizumab an effective and safe alternative therapy in severe refractory atopic dermatitis: A case report.

    abstract:RATIONALE:Atopic dermatitis is a frequent, relapsing, chronic inflammatory skin condition with a deep negative impact on quality of life. Three are the major pathological factors driving its complex pathogenesis: the skin barrier disruption, the altered Th2 cell response and itching. Current management of the disease i...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010897

    authors: Sirufo MM,De Martinis M,Ginaldi L

    更新日期:2018-06-01 00:00:00

  • Association between the use of antibiotics and efficacy of gemcitabine plus nab-paclitaxel in advanced pancreatic cancer.

    abstract::It is unclear whether the use of antibiotics is related to the efficacy of gemcitabine plus nab-paclitaxel (GnP). Therefore, we investigated the association between the use of antibiotics and efficacy of GnP.We conducted a retrospective single center study from January 2014 to December 2018 in Hokkaido University Hosp...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022250

    authors: Nakano S,Komatsu Y,Kawamoto Y,Saito R,Ito K,Nakatsumi H,Yuki S,Sakamoto N

    更新日期:2020-09-25 00:00:00

  • Comparison of neuroendoscopic surgery and craniotomy for supratentorial hypertensive intracerebral hemorrhage: A meta-analysis.

    abstract:BACKGROUND:In recent years, neuroendoscopy has been used as a method for treating intracerebral hemorrhages (ICHs). However, the efficacy and safety of neuroendoscopic surgery is still controversial compared with that of craniotomy. Our aim was to compare the outcomes of neuroendoscopic surgery and craniotomy in patien...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000007876

    authors: Ye Z,Ai X,Hu X,Fang F,You C

    更新日期:2017-09-01 00:00:00

  • Adverse drug events associated with ibrutinib for the treatment of elderly patients with chronic lymphocytic leukemia: A systematic review and meta-analysis of randomized trials.

    abstract:BACKGROUND:Chronic lymphocytic leukemia (CLL) is a rare hematological malignancy classified in the non-Hodgkin's lymphoma category. Ibrutinib, a first-in-class Bruton tyrosine kinase inhibitor has been approved for use in the treatment of CLL. This drug has shown beneficial effects including a higher overall response r...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000016915

    authors: Zhou Y,Lu H,Yang M,Xu C

    更新日期:2019-08-01 00:00:00

  • Genetic association of aromatic hydrocarbon receptor and its repressor gene polymorphisms with risk of rheumatoid arthritis in Han Chinese populations.

    abstract::The goal of this study was to evaluate the potential relationship among polymorphisms of aromatic hydrocarbon receptor, aromatic hydrocarbon receptor repressor, and rheumatoid arthritis (RA) susceptibility as well as the association among the polymorphisms of aromatic hydrocarbon receptor, aromatic hydrocarbon recepto...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006392

    authors: Cheng L,Qian L,Wang GS,Li XM,Li XP

    更新日期:2017-04-01 00:00:00

  • Chinese medicine treatment of mastitis in COVID-19 patients: A protocol for systematic review.

    abstract:BACKGROUND:Assessing the effectiveness and safety of Chinese medicine for the mastitis in COVID-19 patients is the main purpose of this systematic review protocol. METHODS:The following electronic databases will be searched from inception to April 2020: MEDLINE, Ovid, EMBASE, the Cochrane Library, the Allied and Compl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021656

    authors: Wen D,Shi Y,Zhang X,Lv G

    更新日期:2020-08-28 00:00:00

  • Postoperative outcomes after total hip arthroplasty in patients with Parkinson disease: A protocol of case control study.

    abstract:BACKGROUND:Parkinson disease (PD) is a progressive neuromuscular disease associated with bradykinesia, tremor, and postural instability. We aimed to compare outcomes and complications of total hip arthroplasty (THA) between patients with PD and those without. METHODS:A single institution retrospective cohort from 2000...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020018

    authors: Zhang Y,Xiong K,Li R,Yang L

    更新日期:2020-05-01 00:00:00

  • Long-term outcomes of percutaneous radiofrequency thermocoagulation for glossopharyngeal neuralgia: A retrospective observational study.

    abstract::The aim of this study was to investigate the long-term results of computed tomography (CT)-guided percutaneous radiofrequency thermocoagulation (PRT) for glossopharyngeal neuralgia (GPN).A retrospective review of medical records for patients with GPN who were treated with CT-guided PRT between 2003 and 2014 was perfor...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005530

    authors: Wang X,Tang Y,Zeng Y,Ni J

    更新日期:2016-11-01 00:00:00

  • Apnea-hypopnea index decreased significantly after nasal surgery for obstructive sleep apnea: A meta-analysis.

    abstract:BACKGROUND:Nasal surgeries have been applied to obstructive sleep apnea (OSA) patients with nasal obstruction for decades. However, the efficiency of nasal surgery in improving OSA remains controversial.The aim of this study was to identify whether isolated nasal surgery can improve apnea-hypopnea index (AHI). METHODS...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000006008

    authors: Wu J,Zhao G,Li Y,Zang H,Wang T,Wang D,Han D

    更新日期:2017-02-01 00:00:00

  • Clinical effectiveness of acupuncture on Parkinson disease: A PRISMA-compliant systematic review and meta-analysis.

    abstract:BACKGROUND:Parkinson's disease (PD) is the second-most-common chronic and progressive neurodegenerative disease. The long-term use of levodopa leads to a loss of efficacy and to complications. Therefore, many patients with PD have turned to complementary therapies to help relieve their symptoms. Acupuncture is most com...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000005836

    authors: Lee SH,Lim S

    更新日期:2017-01-01 00:00:00

  • Multiple cerebral gliomas mimicking central nervous system inflammatory demyelinating diseases: A rare case with review of literature.

    abstract:RATIONALE:Multiple cerebral gliomas (MCGs), usually classified into multifocal and multicentric subtypes, represent major diagnostic challenges as their clinical, radiologic, and pathohistological features are not uniform, often mimicking brain metastatic tumors or central nervous system inflammatory demyelinating dise...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000009456

    authors: Xiong YJ,Zhao XL,Wang XY,Pan DJ,Tian DS

    更新日期:2017-12-01 00:00:00

  • Sexual behavior of female adolescents on the spread of HIV/AIDS and other STDs in Carriacou.

    abstract::This article explores information relating to female adolescents knowledge, attitudes, and behaviors toward human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) in Carriacou. The authors aimed at finding out whether adolescent females in Carriacou receive adequate information about HIV and...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004800

    authors: Patrice-Coy C,Johnson EJ,Boodram CAS

    更新日期:2016-09-01 00:00:00

  • Expiratory central airway collapse - an overlooked entity?: Two case reports.

    abstract:INTRODUCTION:Expiratory central airway collapse is defined by excessive inward bulging of either tracheobronchial posterior membrane or cartilage. The former is called excessive dynamic airway collapse (EDAC), and the latter, depending on the site of collapse, tracheomalacia, bronchomalacia or tracheobronchomalacia. Du...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022449

    authors: Janowiak P,Rogoza K,Siemińska A,Jassem E

    更新日期:2020-10-16 00:00:00