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Unique origin of Andaman Islanders: insight from autosomal loci.

Abstract：

:Our mtDNA and Y chromosome studies lead to the conclusion that the Andamanese "Negrito" mtDNA lineages have survived in the Andaman Islands in complete genetic isolation from other South and Southeast Asian populations since the initial settlement of the region by the out-of-Africa migration. In order to obtain a robust reconstruction of the evolutionary history of the Andamanese, we carried out a study on the three aboriginal populations, namely, the Great Andamanese, Onge and Nicobarese, using autosomal microsatellite markers. The range of alleles (7-31.2) observed in the studied population and heterozygosity values (0.392-0.857) indicate that the selected STR markers are highly polymorphic in all the three populations, and genetic variability within the populations is significantly high, with a mean gene diversity of 77%. The Andaman "Negrito" populations do not show particular affinities either with the African populations or with the Indian populations, confirming their unique origin. In contrast, Nicobarese show close affinities with the Southeast Asian populations, suggesting their recent entry in the Islands.

journal_name

J Hum Genet

journal_title

Journal of human genetics

authors

Thangaraj K,Chaubey G,Reddy AG,Singh VK,Singh L

doi

10.1007/s10038-006-0026-0

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

800-804

issue

9

eissn

1434-5161

issn

1435-232X

pii

10.1007/s10038-006-0026-0

journal_volume

51

pub_type

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