Abstract:
AIM:To assess genetic diversity and genetic distances among isolated populations from Dagestan. METHODS:A cross-population genetic epidemiology design was applied in ethnically and demographically diverse isolates from Dagestan, some with more than 200 and some with less than 100 generations of demographical history since their founding. RESULTS:The analysis of genetic diversity showed that Dagestan ethnic populations are clearly close to European ethnic populations. The genetic data support the view of them as ancient, highly isolated populations 85%-97% the rate of the endogamy and inbreeding coefficient F=0.010-0.015. Many Dagestan populations have very high prevalence of certain complex diseases such as cardiovascular illnesses, cancer, schizophrenia, mental retardation, and progressive muscular dystrophy. Lifetime morbid risk for schizophrenia in the isolates varied from 0 to 5%. Among the relatives, the number of men with chronic schizophrenia was at least twice as high as women. The average age of onset of schizophrenia was 21.2 years for offspring of consanguineous marriages and 17.4 years for offspring of non-consanguineous marriages (P=0.033). CONCLUSION:The results support the hypothesis that cross-population design provides unique opportunities for observing reliable ancestral haplotypes with disease predisposing loci, as well as population-specific linked loci.
journal_name
Croat Med Jjournal_title
Croatian medical journalauthors
Bulayeva KBsubject
Has Abstractpub_date
2006-08-01 00:00:00pages
641-8issue
4eissn
0353-9504issn
1332-8166journal_volume
47pub_type
杂志文章abstract:AIM:To describe a subset of cases with the unusual clinical and histomorphological presentation of anaplastic large cell lymphoma (ALCL) mimicking fever of unknown origin (FUO) and sepsis. METHODS:A pathology database was searched using full term Systematized Nomenclature of Medicine codes for ALCL to identify 23ALCL ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2008.5.660
更新日期:2008-10-01 00:00:00
abstract:AIM:To elucidate whether Raman spectroscopy aided by extensive spectral database and neural network analysis can be a fast and confident biomarking tool for the diagnosis of various types of cancer. METHODS:Study included 27 patients with 11 different malignant tumors. Using Raman microscopy (RM) a total of 540 Raman ...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2012.53.551
更新日期:2012-12-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract:AIM:To report on our experience with a voice-directed robotic arm for scope management in different procedures for "solo-surgery" and in complex laparoscopic operations. METHODS:A chip card with orders for the robotic arm is individually manufactured for every user. A surgeon gives order through a microphone and the o...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract:AIM:To assess the intrahepatic and extrahepatic bile duct diameter dilatation after laparoscopic cholecystectomy with magnetic resonance cholangiopancreatography. METHODS:Forty-eight patients (35 women, mean age 54.58±11.83 years) underwent laparoscopic cholecystectomy because of gallstones. The intrahepatic and extra...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2020-07-05 00:00:00
abstract::Polish physicians-philosophers tried to find a compromise between medicine as a science and medicine as a healing art. They stated that clinical practice should be transformed into science, bearing in mind that there would be no medicine without the existence of the sick. A perfect physician is a good and wise person ...
journal_title:Croatian medical journal
pub_type: 历史文章,杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract:AIM:To investigate the characteristics and determine risk factors for hantanvirus infection in natural focus of hemorrhagic fever with renal syndrome (HFRS) on the Dinara Mountain, where outbreak of disease emerged among Croatian soldiers in 1995, and to describe the features of HFRS acquired on the Dinara mountain and...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract::Brain death or neurologic death has gradually become recognized as human death over the past decades worldwide. Nevertheless, in Japan, the New York State, and the State of New Jersey, death is declared based not on brain death criteria, but on cardio-pulmonary criteria. In Japan, the 1997 Organ Transplant Law legaliz...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2013.54.75
更新日期:2013-02-01 00:00:00
abstract:: ...
journal_title:Croatian medical journal
pub_type: 社论
doi:
更新日期:2018-12-31 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.458
更新日期:2011-08-15 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2010.51.259
更新日期:2010-06-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2012.53.367
更新日期:2012-08-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2009.50.465
更新日期:2009-10-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2014.55.218
更新日期:2014-06-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1998-06-01 00:00:00
abstract:AIM:To assess clinical and demographic characteristics of Turkish children and adolescents with obsessive-compulsive disorder. METHOD:The study comprised 47 children and adolescents (31 boys and 15 girls) aged between 9 and 15 years, who were diagnosed with obsessive-compulsive disorder according to Diagnostic and Sta...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract::For more than a century, since the introduction of modern hernia repair by Basinni, technical aspects of hernia surgery have been surrounded by controversies. The purpose of this article is to examine these controversies with special attention to (a) mechanical versus degenerative nature of hernias, (b) traditional ti...
journal_title:Croatian medical journal
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2005-12-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章,meta分析
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2010.51.483
更新日期:2010-12-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.171
更新日期:2011-04-15 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:2020-08-31 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2011.52.550
更新日期:2011-08-15 00:00:00
abstract:AIM:Analysis of countertransference problems in the treatment of a heterogeneous group of war veterans. METHOD:The method used in this work was psychodynamic clinical observation and analysis of countertransference phenomena in group therapy. RESULTS:In the beginning of our work, we faced with a regressive group, whi...
journal_title:Croatian medical journal
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2017.58.4
更新日期:2017-02-28 00:00:00
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journal_title:Croatian medical journal
pub_type: 杂志文章
doi:10.3325/cmj.2013.54.206
更新日期:2013-04-01 00:00:00