Abstract：
:Paraneoplastic cerebellar degeneration (PCD) is the most frequent paraneoplastic syndrome affecting the brain. Until now, anti-Tr associated PCD was only seen in patients with Hodgkin's disease. We report a male patient who presented with a progressive ataxia, affecting predominantly the lower limbs and a cerebellar dysarthria. Extensive diagnostic approach initially showed no evidence of tumor. The patient was found to have anti-Tr antibodies in his serum. Fourteen months after onset of symptoms a whole body PET-scan showed a pathological focus at the right hilus of the lungs. A mediastinoscopy was performed and peribronchial node sampling was done. The anatomopathological analysis revealed a non-well differentiated squamous cell carcinoma. This is the first report about the association between an anti-Tr associated PCD and squamous cell carcinoma.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Bruylant K,Crols R,Humbel RL,Appel B,De Deyn PPdoi
10.1016/j.clineuro.2005.01.008subject
Has Abstractpub_date
2006-06-01 00:00:00pages
415-7issue
4eissn
0303-8467issn
1872-6968pii
S0303-8467(05)00019-3journal_volume
108pub_type
杂志文章abstract：OBJECTIVE:To compare clinical evaluation, electrophysiological investigation and magnetic resonance findings in assessing the severity of idiopathic carpal tunnel syndrome. PATIENTS AND METHODS:Seventy-four patients with idiopathic carpal tunnel syndrome were prospectively recruited. Clinical evaluation included sympt...
journal_title：Clinical neurology and neurosurgery
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journal_title：Clinical neurology and neurosurgery
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更新日期：2006-09-01 00:00:00
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pub_type： 杂志文章,meta分析,评审
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更新日期：2017-12-01 00:00:00
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