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Next generation sequencing for neurological diseases: new hope or new hype?

Abstract：

:Over the past year huge advances have been made in our ability to determine the genetic aetiology of many neurological diseases through the utilisation of next generation sequencing platforms. This technology is, on a daily basis, providing new breakthroughs in neurological disease. The aim of this article is to clearly describe the technological platforms, methods of data analysis, established breakthroughs, and potential future clinical and research applications of this innovative and exciting technique which has relevance to all those working within clinical neuroscience.

journal_name

Clin Neurol Neurosurg

journal_title

Clinical neurology and neurosurgery

authors

Keogh MJ,Chinnery PF

doi

10.1016/j.clineuro.2012.09.030

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

948-53

issue

7

eissn

0303-8467

issn

1872-6968

pii

S0303-8467(12)00522-7

journal_volume

115

pub_type

杂志文章,评审

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