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Mucolytic-antifoam solution for reduction of artifacts during endoscopic ultrasonography: a randomized controlled trial.

Abstract：

:Gastric mucus and air bubbles are frequent sources of artifacts during endoscopic ultrasonography (EUS). To reduce these artifacts, we prepared a mucolytic-antifoam solution consisting of simethicone, acetylcysteine, and sodium bicarbonate and performed a prospective randomized and controlled trial comparing this solution (21 patients) to a placebo (22 patients) during EUS. Eight patients in the drug group received a perfect score for both mucolytic and antifoam effect compared with none in the placebo group (p less than 0.001). For overall rating, the drug group received a total of 10 excellents and 9 goods compared with 9 goods, 10 satisfactories, and 1 unacceptable in the placebo group (p less than 0.001). There were no complications associated with the solution. In conclusion, a mucolytic-antifoam solution improved endoscopic visualization and reduced artifacts during EUS study. Its routine use during EUS procedures is therefore recommended.

journal_name

Gastrointest Endosc

journal_title

Gastrointestinal endoscopy

authors

Yiengpruksawan A,Lightdale CJ,Gerdes H,Botet JF

doi

10.1016/s0016-5107(91)70825-0

keywords:

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

543-6

issue

5

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(91)70825-0

journal_volume

37

pub_type

临床试验,杂志文章,随机对照试验

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