Controlling market power and price spikes in electricity networks: Demand-side bidding.

abstract：:The human amygdala plays a key role in recognizing facial emotions and neurons in the monkey and human amygdala respond to the emotional expression of faces. However, it remains unknown whether these responses are driven primarily by properties of the stimulus or by the perceptual judgments of the perceiver. We invest...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wang S,Tudusciuc O,Mamelak AN,Ross IB,Adolphs R,Rutishauser U

更新日期：2014-07-29 00:00:00

abstract：:A microfluidic mixer is applied to study the kinetics of calmodulin conformational changes upon Ca2+ binding. The device facilitates rapid, uniform mixing by decoupling hydrodynamic focusing from diffusive mixing and accesses time scales of tens of microseconds. The mixer is used in conjunction with multiphoton micros...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Park HY,Kim SA,Korlach J,Rhoades E,Kwok LW,Zipfel WR,Waxham MN,Webb WW,Pollack L

更新日期：2008-01-15 00:00:00

abstract：:We address the stability of multicharged finite systems driven by Coulomb forces beyond the Rayleigh instability limit. Our exploration of the nuclear dynamics of heavily charged Morse clusters enabled us to vary the range of the pair potential and of the fissibility parameter, which results in distinct fragmentation ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Last I,Levy Y,Jortner J

更新日期：2002-07-09 00:00:00

abstract：:Assemblies formed by solid particles at interfaces have been widely studied because they serve as models of molecular phenomena, including molecular self-assembly. Solid particles adsorbed at interfaces also provide a means of stabilizing liquid-liquid emulsions and synthesizing materials with tunable mechanical, opti...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Koenig GM Jr,Lin IH,Abbott NL

更新日期：2010-03-02 00:00:00

abstract：:Genetic manipulation of the alpha(2A)-adrenergic receptor (alpha(2A)-AR) in mice has revealed the role of this subtype in numerous responses, including agonist-induced hypotension and sedation. Unexpectedly, alpha(2)-agonist treatment of mice heterozygous for the alpha(2A)-AR (alpha(2A)-AR(+/-)) lowers blood pressure ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tan CM,Wilson MH,MacMillan LB,Kobilka BK,Limbird LE

更新日期：2002-09-17 00:00:00

abstract：:Replication-defective human adenovirus (Ad) group C transducing vectors, most of which have the E1A, E1B, and E3 genes deleted, are highly inflammatory despite the fact that the parental viruses typically cause subclinical or mild infections. To investigate this paradox, the roles that the E1A, E1B, and E3 genes play ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Schaack J,Bennett ML,Colbert JD,Torres AV,Clayton GH,Ornelles D,Moorhead J

更新日期：2004-03-02 00:00:00

abstract：:We tested a theoretical prediction that patterns of excitatory input activity that consistently fail to activate target neurons sufficiently to induce synaptic potentiation will instead cause a specific synaptic depression. To realize this situation experimentally, the Schaffer collateral projection to area CA1 in rat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dudek SM,Bear MF

更新日期：1992-05-15 00:00:00

abstract：:The remarkable strength of glasses is examined using the random first order transition theory of the glass transition. The theory predicts that strength depends on elastic modulus but also on the configurational energy frozen in when the glass is prepared. The stress catalysis of cooperative rearrangements of the type...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wisitsorasak A,Wolynes PG

更新日期：2012-10-02 00:00:00

abstract：:We explore the question of what are the best ligands for macromolecular targets. A survey of experimental data on a large number of the strongest-binding ligands indicates that the free energy of binding increases with the number of nonhydrogen atoms with an initial slope of approximately -1.5 kcal/mol (1 cal = 4.18 J...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kuntz ID,Chen K,Sharp KA,Kollman PA

更新日期：1999-08-31 00:00:00

abstract：:A total of 289,868 locus tests, based on 28 different protein phenotypes and using one-dimensional electrophoresis to detect variant proteins, has yielded one probable mutation in the offspring of "proximally exposed" parents, who received an estimated average gonadal exposure of 31 to 39 rem in the atomic bombings of...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Neel JV,Satoh C,Hamilton HB,Otake M,Goriki K,Kageoka T,Fujita M,Neriishi S,Asakawa J

更新日期：1980-07-01 00:00:00

abstract：:A pure population of mast cells was obtained after 14 days of culturing mouse bone marrow cells in the presence of medium derived from concanavalin A-stimulated mouse spleen cells. The cells were characterized as mast cells by their morphologic appearance and histologic staining, by their histamine content (450 ng per...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Razin E,Cordon-Cardo C,Good RA

更新日期：1981-04-01 00:00:00

abstract：:Mus poschiavinus x M. musculus hybrids, which had seven metacentric chromosomes derived from the poschiavinus complement, were repeatedly backcrossed to M. musculus and selected for the chromosome carrying the H-2 complex. A line called T1/Klj was established which had one metacentric chromosome. It was shown by linka...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Klein J

更新日期：1971-07-01 00:00:00

abstract：:All cell functions that involve membrane deformation or a change in cell shape (e.g., endocytosis, exocytosis, cell motility, and cytokinesis) are regulated by membrane tension. While molecular contacts between the plasma membrane and the underlying actin cytoskeleton are known to make significant contributions to mem...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Nambiar R,McConnell RE,Tyska MJ

更新日期：2009-07-21 00:00:00

abstract：:The ability of a specialized herbivore to overcome the chemical defense of a particular plant taxon not only makes it accessible as a food source but may also provide metabolites to be exploited for communication or chemical defense. Phyllotreta flea beetles are adapted to crucifer plants (Brassicales) that are defend...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Beran F,Pauchet Y,Kunert G,Reichelt M,Wielsch N,Vogel H,Reinecke A,Svatoš A,Mewis I,Schmid D,Ramasamy S,Ulrichs C,Hansson BS,Gershenzon J,Heckel DG

更新日期：2014-05-20 00:00:00

abstract：:We show that the motion of a slightly compressible fluid is near that of an incompressible fluid. That is, for a given initial velocity field, the motion of a compressible fluid with large sound speed is near to that of an idealized incompressible fluid. We consider the compressible fluid motion in Lagrangian coordina...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ebin DG

更新日期：1975-02-01 00:00:00

abstract：:The coupling of calcium transport to ATP hydrolysis in rabbit muscle sarcoplasmic reticulum vesicles was determined under steady-state conditions in the presence of 5 mM oxalate and using various concentrations of vesicles to modulate the concentration of free Ca2+ in the medium. This experimental approach takes advan...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gafni A,Boyer PD

更新日期：1985-01-01 00:00:00

abstract：:All decisions, whether they are personal, public, or business-related, are based on the decision maker's beliefs and values. Science can and should help decision makers by shaping their beliefs. Unfortunately, science is not easily accessible to decision makers, and scientists often do not understand decision makers' ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： von Winterfeldt D

更新日期：2013-08-20 00:00:00

abstract：:Neutrinos represent a new "window" to the Universe, spanning a large range of energy. We discuss the science of neutrino astrophysics and focus on two energy regimes. At "lower" energies ( approximately 1 MeV), studies of neutrinos born inside the sun, or produced in interactions of cosmic rays with the atmosphere, ha...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Besson D,Cowen D,Selen M,Wiebusch C

更新日期：1999-12-07 00:00:00

abstract：:IL-17 has been implicated in a number of inflammatory diseases, but the conditions of antigen exposure that drive the generation of Th17 responses have not been well defined. Epicutaneous (EC) immunization of mice with ovalbumin (OVA), which causes allergic skin inflammation with many characteristics of the skin lesio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： He R,Oyoshi MK,Jin H,Geha RS

更新日期：2007-10-02 00:00:00

abstract：:Genetically obese (ob/ob) mice, mice that became obese after treatment with gold thioglucose, and lean animals were studied in the euthyroid state, after induction of hypothyroidism, and after treatment with triiodothyronine. The activity of glycerol 3-phosphate dehydrogenase (sn-glycerol-3-phosphate:(acceptor) oxidor...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： York DA,Bray GA,Yukimura Y

更新日期：1978-01-01 00:00:00

abstract：:The CuAAC reaction (click chemistry) has been used in conjunction with solid-phase synthesis to produce catalytically active hairpin ribozymes around 100 nucleotides in length. Cross-strand ligation through neighboring nucleobases was successful in covalently linking presynthesized RNA strands with high efficiency (tr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： El-Sagheer AH,Brown T

更新日期：2010-08-31 00:00:00

abstract：:Several tissue culture cell lines that were transformed by a tumor virus have been found to react with an agglutinin, while under identical conditions their untransformed parent cell lines did not agglutinate. Since a short treatment of the parent cell line with low concentrations of proteases exposed the same aggluti...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Burger MM

更新日期：1969-03-01 00:00:00

abstract：:NKp46 is a cell surface receptor expressed on natural killer (NK) cells, on a minute subset of T cells, and on a population of innate lymphoid cells that produce IL-22 and express the transcription factor retinoid-related orphan receptor (ROR)-γt, referred to as NK cell receptor (NKR)(+)ROR-γt(+) cells. Here we descri...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Narni-Mancinelli E,Chaix J,Fenis A,Kerdiles YM,Yessaad N,Reynders A,Gregoire C,Luche H,Ugolini S,Tomasello E,Walzer T,Vivier E

更新日期：2011-11-08 00:00:00

abstract：:Direct cell-cell communication is crucial for many processes in biology, particularly embryogenesis, interactions between hematopoetic cells, and in the nervous system. This communication is often mediated by the binding of receptors to cognate ligands at a cell-cell junction. One such interaction that is very importa...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Qi S,Krogsgaard M,Davis MM,Chakraborty AK

更新日期：2006-03-21 00:00:00

abstract：:The number of x-irradiated mammalian cells surviving is markedly increased when the cells are incubated with an uncoupler of oxidative phosphorylation prior to or immediately after irradiation. This increase is greater in plateau-phase cells than in exponentially growing cells. The increase in survival is related to t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Laval F

更新日期：1980-05-01 00:00:00

abstract：:In response to hypoxia the hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of a network of genes encoding erythropoietin, vascular endothelial growth factor, and several glycolytic enzymes. HIF-1 consists of a heterodimer of two basic helix-loop-helix PAS (Per/Arnt/Sim) proteins, HIF-1alpha and ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kallio PJ,Pongratz I,Gradin K,McGuire J,Poellinger L

更新日期：1997-05-27 00:00:00

abstract：:Age-related macular degeneration (AMD) is the most common cause of blindness for individuals age 50 and above in the developed world. Abnormal growth of choroidal blood vessels, or choroidal neovascularization (CNV), is a hallmark of the neovascular (wet) form of advanced AMD and leads to significant vision loss. A gr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hasegawa E,Inafuku S,Mulki L,Okunuki Y,Yanai R,Smith KE,Kim CB,Klokman G,Bielenberg DR,Puli N,Falck JR,Husain D,Miller JW,Edin ML,Zeldin DC,Lee KSS,Hammock BD,Schunck WH,Connor KM

更新日期：2017-09-05 00:00:00

abstract：:This study demonstrates that significantly shortened telomeres are a hallmark of cardiomyocytes (CMs) from individuals with end-stage hypertrophic cardiomyopathy (HCM) or dilated cardiomyopathy (DCM) as a result of heritable defects in cardiac proteins critical to contractile function. Positioned at the ends of chromo...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chang ACY,Chang ACH,Kirillova A,Sasagawa K,Su W,Weber G,Lin J,Termglinchan V,Karakikes I,Seeger T,Dainis AM,Hinson JT,Seidman J,Seidman CE,Day JW,Ashley E,Wu JC,Blau HM

更新日期：2018-09-11 00:00:00

abstract：:Electrically excitable cells harness voltage-coupled calcium influx to transmit intracellular signals, typically studied in neurons and cardiomyocytes. Despite intense study in higher organisms, investigations of voltage and calcium signaling in bacteria have lagged due to their small size and a lack of sensitive tool...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bruni GN,Weekley RA,Dodd BJT,Kralj JM

更新日期：2017-08-29 00:00:00

abstract：:A structural gene for the alpha-subunit of RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase; EC 2.7.7.6) has been identified and mapped between spcA and trkA, near 64 min on the E. coli chromosome. It appears to be coordinately expressed and possibly cotranscribed with the genes for ribosomal proteins...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jaskunas SR,Burgess RR,Nomura M

更新日期：1975-12-01 00:00:00