Differentiation between carcinoid and sarcoid with F-18 FDG PET and In-111 pentetreotide.

Abstract:

:A patient who presented with weight loss and recurrent left lower lobe pneumonia was diagnosed with endobronchial carcinoid. Chest CT scan demonstrated extensive mediastinal and hilar lymphadenopathy suggesting stage IIIB disease, but radionuclide imaging with In-111 pentetreotide and F-18 FDG PET diagnosed 2 distinct pathologic processes based on functional differences between neuroendocrine tumors (expressing somatostatin receptors) and sarcoidosis (intensely FDG-avid). The possible association of carcinoid with sarcoidosis and sarcoid-like reactions in regional lymph nodes should always be considered, and the staging process should include both anatomic and functional imaging and biopsy confirmation of suspected metastatic lesions.

journal_name

Clin Nucl Med

authors

Avram AM,Mackie GC,Schneider BJ,Kalemkerian GP,Shulkin BL

doi

10.1097/01.rlu.0000204200.66112.a9

keywords:

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

197-200

issue

4

eissn

0363-9762

issn

1536-0229

pii

00003072-200604000-00003

journal_volume

31

pub_type

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