Abstract:
OBJECTIVE:To analyze whether nasal continuous positive airway pressure (CPAP) reduces oxidative stress in patients with sleep apnea-hypopnea syndrome (SAHS). PATIENTS AND METHODS:Thirty-six patients with SAHS requiring nasal CPAP treatment and 10 controls in whom SAHS was ruled out were enrolled. Oxidative stress was evaluated by measuring plasma malondialdehyde (MDA) concentrations to assess lipid peroxidation at the beginning of the study and then again after a mean (SD) of 2.9 (0.6) months of nasal CPAP. Plasma MDA concentrations were determined by measuring thiobarbituric acid reactive substances. We controlled for the following factors known to influence oxidative stress: age, sex, use of vitamin supplements, smoking habit, body mass index (kg/m2), ischemic cardiopathy, hypertension, diabetes, and hypercholesterolemia. RESULTS:The mean age of patients with SAHS was 51.4 (9.9) years and the mean body mass index was 32.9 (5.3) kg/m2. Nasal CPAP was titrated to a mean pressure of 8.9 (3.4) cm H2O. The mean score on the Epworth sleepiness scale was 10.2 (4.3) before treatment and 4.2 (2.8) after treatment (P<.001). The apnea-hypopnea index decreased from 43.7 (22.6) before treatment to 4 (3.5) after treatment (P<.001). Mean MDA concentrations in patients with SAHS were 2.0 (1.1) micromol/mL before treatment and decreased significantly to 1.6 (.07) micromol/mL after treatment, whereas MDA concentrations remained unchanged in control subjects. CONCLUSIONS:Nasal CPAP treatment significantly reduced oxidative stress in patients with SAHS in our study.
journal_name
Arch Bronconeumoljournal_title
Archivos de bronconeumologiaauthors
Hernández C,Abreu J,Abreu P,Colino R,Jiménez Adoi
10.1016/s1579-2129(06)60130-4keywords:
subject
Has Abstractpub_date
2006-03-01 00:00:00pages
125-9issue
3eissn
0300-2896issn
1579-2129pii
13085561journal_volume
42pub_type
杂志文章abstract::Organizing pneumonia is a well-differentiated clinical and histologic entity whose onset is usually subacute with respiratory symptoms and pulmonary infiltrates. Its origin may be unknown (cryptogenic) or it may be associated with various medical conditions, infectious diseases, or drugs. Diagnosis is confirmed by the...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To analyze the network structure of collaboration between medical centers sharing authorship of scientific articles on smoking. MATERIAL AND METHODS:Articles reporting smoking research by authors from 2 or more Spanish medical centers between 1999 and the end of 2003 were identified through the Science Citat...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s1579-2129(07)60089-5
更新日期:2007-07-01 00:00:00
abstract:INTRODUCTION:The objective of this analysis was the evaluation of a new national circuit used for diagnosing alpha1 antitrypsin deficiency (AATD) based on multiplex technology using online registration and mail posted samples from dried blood spots (DBS) and buccal swabs. METHODS:This is an observational, ongoing stud...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.04.014
更新日期:2021-01-01 00:00:00
abstract::A review has been made of original articles on invasive pneumology techniques, interstitial diseases and lung transplantation, published in the Archivos de Bronconeumología during the year 2008. We have selected the publication by Martínez-Olondrins et al on the mediastinal staging of bronchogenic carcinoma by
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/S0300-2896(09)70271-6
更新日期:2009-01-01 00:00:00
abstract::In view of the presentations in the First National Forum of Trainee Pneumologists, the present article focuses on infectious pleural effusions and on the study of possible markers of malignant disease in asbestos-exposed individuals. The yield of the distinct techniques for the diagnosis of tuberculous pleural effusio...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/S0300-2896(09)72854-6
更新日期:2009-01-01 00:00:00
abstract::Chlamydia pneumoniae has often been implicated in respiratory tract infections concomitant with other pathogens. Although this agent has also been associated with other nonrespiratory diseases, to our knowledge it has never been described with autoimmune hemolytic anemia. We present a case of pneumonia in which C. pne...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:10.1016/s0300-2896(15)30772-9
更新日期:1996-05-01 00:00:00
abstract::Ten cases of pulmonary mycetoma diagnosed in our service between 1985-1992 were retrospectively studied. Clinical methodology followed in the study is commented and the different therapeutic options are reviewed, so the literature concerning this process. The unspecificity of serum precipitins with Aspergillus is emph...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)31048-6
更新日期:1994-08-01 00:00:00
abstract::We report a case of pleural effusion, pericardial thickening, and pulmonary involvement in a patient with dry cough, dyspnea, edema, and changes in the skin of the lower limbs. Treatment with cabergoline (Sogilen) had been started 4 months earlier. Pleural effusion, pericardial thickening, and impaired pulmonary funct...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60118-9
更新日期:2007-09-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2017.11.015
更新日期:2018-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60376-5
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVE:To assess the effect of adequate outpatient care as defined by guidelines of the Global Initiative for Asthma (GINA) on the long-term outcome of near-fatal asthma. PATIENTS AND METHODS:Fifty-three patients who had experienced a near-fatal attack of asthma were treated according to the GINA guidelines and fol...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30789-4
更新日期:1996-04-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60232-2
更新日期:2005-06-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2015.07.017
更新日期:2016-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,多中心研究
doi:10.1016/s0300-2896(03)75414-3
更新日期:2003-09-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2003-12-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/S0300-2896(10)70026-0
更新日期:2010-01-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2008-09-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2012.08.002
更新日期:2013-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(01)75065-x
更新日期:2001-05-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(07)60008-1
更新日期:2006-12-01 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/j.arbres.2020.05.030
更新日期:2020-06-26 00:00:00
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journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s1579-2129(06)60284-x
更新日期:2005-10-01 00:00:00
abstract::The prevalence of primary ciliary dyskinesia syndrome (PCDS) in Western countries is of 1/40,000 but is 13% in patients with bronchiectasis. The aim of this study was to determine the prevalence of PCDS in patients with bronchiectasis and sinusitis, including whether or not these patients present specific clinical sig...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)31145-5
更新日期:1994-01-01 00:00:00
abstract::Sixty patients diagnosed as having chronic respiratory diseases were surveyed in order to establish how many knew the name of their disease, the medications they were taking, the name of the medical specialty dedicated to treating their condition and the nature of spirometry. Only 23 patients (38%) knew the name of th...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)31111-x
更新日期:1994-03-01 00:00:00
abstract:INTRODUCTION:Primary palmar hyperhidrosis (PPH) mainly affects the sympathetic ganglia. This study aims to analyze the histopathological changes in the sympathetic ganglia of patients with PPH. MATERIAL AND METHOD:We studied 55 tissue samples from 35 patients with PPH who underwent T2-T3 gangliectomy for definitive tr...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(03)75337-x
更新日期:2003-03-01 00:00:00
abstract::This prospective descriptive study evaluated the utility of dobutamine in studying pulmonary vascular compliance in patients with lung neoplasms who are high risk candidates for lung resection. Seventeen consecutive patients meeting one of the following inclusion criteria were enrolled: FEV1 < 60% of theoretical value...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:10.1016/s0300-2896(15)30613-x
更新日期:1997-05-01 00:00:00
abstract::Changes in nutritional status, such as weight loss and malnutrition, are a very common complication in patients with chronic obstructive pulmonary disease (COPD). These changes primarily affect the patients' quality of life and functional capacity and they are also independent prognostic indicators of both morbidity a...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章,评审
doi:
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:To determine the number of smokers, their demographic characteristics, and the stages of change among patients visiting health care centers. PATIENTS AND METHODS:Descriptive cross-sectional study carried out at 7 primary health care centers in Health District 5 of the Autonomous Community of Valencia. RESU...
journal_title:Archivos de bronconeumologia
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00