'Atypical TIAs' may herald cardiac rather than cerebral events.

Abstract:

:Sixty-four patients with atypical transient cerebral or visual symptoms that could not be classified as unequivocal TIAs nor as migraine, epilepsy or neurosis, were followed up for a mean of 3.75 years (range 11 months and 9 years, 240 patient years). Their mean age was 55 years. Only two patients suffered a (non-disabling) stroke, but eight patients had a major cardiac event: fatal myocardial infarction in three, sudden death in one and non-fatal myocardial infarction in four patients. Seven of these eight patients were known to have cardiovascular risk factors. Visual symptoms were relatively benign with regard to cardiac events (2 events in 28 patients), whereas dizziness alone and focal sensory symptoms alone were more strongly associated with subsequent cardiac complications (2 out of 4, and 4 out of 13 patients, respectively). In a control group of 185 patients with 'typical' TIAs or minor strokes, followed for a total of 233 patient years, seven patients had a ischaemic stroke, and only one a cardiac event. Our results suggest that patients with atypical transient cerebral deficits and cardiovascular risk factors may carry a low risk of subsequent stroke, but a high risk of major cardiac events.

journal_name

Clin Neurol Neurosurg

authors

Koudstaal PJ,van Gijn J,Naarding P,de Kluyver E,Pop GA,Staal A

doi

10.1016/0303-8467(91)90049-u

keywords:

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

107-14

issue

2

eissn

0303-8467

issn

1872-6968

pii

0303-8467(91)90049-U

journal_volume

93

pub_type

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