Abstract：
:Nausea and vomiting are considered one of the most distressing side-effects of chemotherapy. Complete control of acute and delayed emesis improves quality of life and increases adherence to treatment. The frequency of nausea and vomiting depends primarily on the emetogenic potential of the chemotherapeutic agents used. With the standard antiemetic therapy (5HT-3 receptor antagonists in combination with dexamethasone) approximately 13% of patients receiving chemotherapy have vomiting in the acute phase and almost 50% in the delayed phase. A new group of antiemetic drugs, the neurokinin-1 receptor antagonists, in combination with standard therapy significantly improves emesis protection in the acute and in the delayed phase, although control of nausea is not so effective. Nowadays chemotherapy-induced emesis still occurs. Recent developments in antiemetic therapy and responsibility to achieve the best control of nausea and vomiting in patients receiving chemotherapy justified a review of this problem, which is frequently underestimated by physicians and nurses.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Gómez-Raposo C,Feliú-Batlle J,González-Baróna Mdoi
10.1157/13084022keywords:
subject
Has Abstractpub_date
2006-02-04 00:00:00pages
143-51issue
4eissn
0025-7753issn
1578-8989pii
S0025-7753(06)71859-0journal_volume
126pub_type
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