Hyperbaric oxygen should not be used in the management of hemorrhagic cystitis in patients with Fanconi anemia.


:Hemorrhagic cystitis (HC) is a common complication after stem cell transplantation (SCT) that occurs more frequently in patients with Fanconi anemia (FA) because of hypersensitivity of their cells to the agents used in the preparation for SCT (chemo and radiation). Many HC cases respond to therapy with hyperhydration and maintenance of adequate platelet counts, but refractory cases may require additional measures such as the use of prostaglandins, alum, or hyperbaric oxygen (HBO). We report here an unusual complication to HBO therapy in a FA patient consisting of generalized edema mimicking capillary leak syndrome but with no pulmonary edema or ascites.


Pediatr Blood Cancer


Pediatric blood & cancer


Al-Seraihi A,Ayas M





Has Abstract


2007-11-01 00:00:00












  • Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

    abstract::We present three pediatric patients with BRAFV600E mutant high-grade gliomas treated by vemurafenib on a nominative authorization level at our institution. One patient with anaplastic ganglioglioma experienced confirmed partial tumor response and significant clinical improvement and she is alive 20 months after start ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Bautista F,Paci A,Minard-Colin V,Dufour C,Grill J,Lacroix L,Varlet P,Valteau-Couanet D,Geoerger B

    更新日期:2014-06-01 00:00:00

  • Persistent jaundice in an infant with homozygous beta thalassemia due to co-inherited Crigler-Najjar syndrome.

    abstract::Clinically apparent jaundice is unusual in patients with beta-thalassemia major. Co-inheritance of Gilbert syndrome has been reported to cause hyperbilirubinemia in these subjects. Crigler-Najjar syndrome is another rare disorder of bilirubin metabolism caused by mutation in the gene coding the enzyme UGT1A1. We repor...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Aggarwal V,Seth A,Sharma S,Aneja S,Sammarco P,Fabiano C

    更新日期:2010-04-01 00:00:00

  • Impact of Socioeconomic Status on Timing of Relapse and Overall Survival for Children Treated on Dana-Farber Cancer Institute ALL Consortium Protocols (2000-2010).

    abstract:BACKGROUND:Population-based evidence suggests that lower socioeconomic status (SES) negatively impacts the overall survival (OS) of children with leukemia; however, the relationships between SES and treatment-related mortality, relapse, and timing of relapse remain unclear. PROCEDURE:We examined OS, event-free surviva...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Bona K,Blonquist TM,Neuberg DS,Silverman LB,Wolfe J

    更新日期:2016-06-01 00:00:00

  • Prognostic factors and treatment outcome in childhood Hodgkin disease.

    abstract:BACKGROUND:The goals of this study included: (1) Identification of factors prognostic for event-free survival (EFS) and overall survival (OS), and (2) Definition of risk groups for risk adapted therapy in children with Hodgkin disease (HD). PROCEDURE:From 1991 to 2003, 69 children with newly diagnosed, untreated biops...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Oguz A,Karadeniz C,Okur FV,Citak EC,Pinarli FG,Bora H,Akyurek N

    更新日期:2005-10-15 00:00:00

  • Early cardiac outcomes following contemporary treatment for childhood acute myeloid leukemia: a North American perspective.

    abstract:BACKGROUND:Anthracycline agents are used for treatment of acute myeloid leukemia (AML) but may cause late-onset cardiomyopathy. Current frontline therapy for AML in North America, as reflected in the approach of the Children's Oncology Group (COG) and other pediatric consortia, is adapted from the anthracyline-intensiv...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Orgel E,Zung L,Ji L,Finklestein J,Feusner J,Freyer DR

    更新日期:2013-09-01 00:00:00

  • Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literature.

    abstract::Anaplastic oligodendroglioma (AO) is rare in children. Treatment typically consists of varying combinations of surgery, chemotherapy, and radiotherapy. We present a pediatric case of frontal lobe AO with periventricular subcallosal extension and local leptomeningeal involvement. The isocitrate dehydrogenase (IDH) wild...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Sorge C,Li R,Singh S,Reddy AT,Solomon DA,Perry A,Friedman GK

    更新日期:2017-12-01 00:00:00

  • Efficacy of surgery combined with postoperative 125 I interstitial brachytherapy for treatment of acinic cell carcinoma of the parotid gland in children and adolescents.

    abstract:BACKGROUND:Acinic cell carcinoma (AciCC) is rare in children; therefore, reaching a consensus on its management is challenging and radiotherapy is limited by concerns about long-term toxicity. The purpose of this study is to analyze the effectiveness and safety of surgery plus postoperative 125 I interstitial brachythe...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Li J,Zhang J,Lyu XM,Huang MW,Zheng L,Zhang JG

    更新日期:2020-07-01 00:00:00

  • Role of bone marrow biopsy for staging new patients with Ewing sarcoma: A systematic review.

    abstract::The incidence of bone marrow metastasis (BMM) in newly diagnosed Ewing sarcoma (ES) is variable across studies. An optimal staging strategy for detecting BMM is not defined. While bone marrow (BM) biopsy and/or aspirate (BMBA) have been the gold standard, [F-18]fluorodeoxyglucose positron emission tomography (FDG-PET)...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Campbell KM,Shulman DS,Grier HE,DuBois SG

    更新日期:2021-02-01 00:00:00

  • Osteoporosis in children with cancer.

    abstract::As increasing numbers of childhood cancer patients are surviving, the long-term complications of the disease and its treatment have become ever more increasingly important. Reduced bone mineral density and increased fracture risk have been reported during and after treatment of children with cancer. The causes of oste...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: van der Sluis IM,van den Heuvel-Eibrink MM

    更新日期:2008-02-01 00:00:00

  • Significant inconsistency among pediatric oncologists in the use of the neutropenic diet.

    abstract:BACKGROUND:The role of the neutropenic diet in the development of infections in oncology and stem cell transplant (SCT) patients is controversial. There is no data on the use of the neutropenic diet among pediatric oncologists. METHODS:A self-administered electronic survey was sent to 1,639 pediatric oncologists at 19...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Braun LE,Chen H,Frangoul H

    更新日期:2014-10-01 00:00:00

  • A prognostic evaluation of vascular endothelial growth factor in children and young adults with osteosarcoma.

    abstract:BACKGROUND:The potential role of VEGF in osteosarcoma has been evaluated in several studies. The majority of them included heterogeneous and limited series of patients, giving conflicting results. The aim of presented study is to evaluate the prognostic role of VEGF-A in biopsy samples of clinically homogeneous group o...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Ługowska I,Woźniak W,Klepacka T,Michalak E,Szamotulska K

    更新日期:2011-07-15 00:00:00

  • Review of radiotherapy dose and volume for intracranial ependymoma.

    abstract:BACKGROUND:Radiotherapy (RT) is well established in the management of intracranial ependymoma (EP) and post-operative RT is employed for the majority of patients. There are no randomised trials of RT in EP and evidence for dose and volume relies on retrospective single institution series, usually comprising a heterogen...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Taylor RE

    更新日期:2004-05-01 00:00:00

  • Assessment of Financial Burden as a Standard of Care in Pediatric Oncology.

    abstract::Family financial hardship has emerged as a burden of pediatric cancer treatment with negative implications for family well-being. As part of an extensive project to create evidence-based standards for the psychosocial care of children with cancer, we performed a literature review of pediatric cancer-associated financi...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Pelletier W,Bona K

    更新日期:2015-12-01 00:00:00

  • Evaluating physical function in an adolescent bone tumor population.

    abstract:BACKGROUND:Survival rates for patients with bone tumors have increased dramatically over the past few decades. Unfortunately, many patients face functional limitations resulting from disease management, but there is little evidence regarding physical functioning in adolescents with bone tumors. This lack is largely due...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Pakulis PJ,Young NL,Davis AM

    更新日期:2005-10-15 00:00:00

  • Changes in hepatitis B antibody status after chemotherapy in children with acute lymphoblastic leukemia.

    abstract:BACKGROUND:Children with cancer may be at an increased risk of infection with hepatitis B virus (HBV) when levels of hepatitis B antibodies are reduced owing to chemotherapy-induced immunosuppression. This study evaluated the changes in HBV antibody status and HBV infections after chemotherapy in children with acute ly...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Choi YB,Lee NH,Yi ES,Kim YJ,Koo HH

    更新日期:2019-12-01 00:00:00

  • Malignant ectomesenchymoma in children and adolescents: report from the Cooperative Weichteilsarkom Studiengruppe (CWS).

    abstract:BACKGROUND:Malignant ectomesenchymoma (MEM) is a soft tissue tumor with heterologous rhabdomyoblastic components believed to arise from pluripotent migratory neural crest cells. To date merely 50 cases have been published and the knowledge about the course of disease and optimal treatment is limited. METHODS:Six patie...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Dantonello TM,Leuschner I,Vokuhl C,Gfroerer S,Schuck A,Kube S,Nathrath M,Bernbeck B,Kaatsch P,Pal N,Ljungman G,Bielack SS,Klingebiel T,Koscielniak E,CWS.

    更新日期:2013-02-01 00:00:00

  • Sleep disordered breathing risk in childhood cancer survivors: an exploratory study.

    abstract:BACKGROUND:Sleep disordered breathing (SDB) is emerging as a significant health condition for children. The purpose of this study is to evaluate SDB symptoms in childhood cancer survivors and identify associations with quality of life (QOL) and psychological symptoms. PROCEDURE:A sample of 62 survivors aged 8-18 years...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Kathy R,Anna G,Gallicchio L,Gamaldo C

    更新日期:2015-04-01 00:00:00

  • A unique phenotype of T-cell acute lymphoblastic leukemia in a patient with GATA2 haploinsufficiency.

    abstract::Germline or acquired mutations involving the GATA-binding protein gene (GATA2) have been linked to a variety of clinical conditions. In addition, patients harboring GATA2 mutations have a striking predisposition to develop myeloid malignancies, such as myelodysplastic syndrome or acute myeloid leukemia, but not acute ...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Esparza O,Xavier AC,Atkinson TP,Hill BC,Whelan K

    更新日期:2019-06-01 00:00:00

  • Local lymph node involvement in pediatric renal cell carcinoma: a report from the Italian TREP project.

    abstract:BACKGROUND:One of the most important adverse prognostic factors for adult renal cell carcinoma (RCC) is the retroperitoneal lymph node involvement. The aim of this article is to study the prognostic significance of local lymph node involvement in pediatric RCC and the role of retroperitoneal lymph node dissection (RLND...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Indolfi P,Bisogno G,Cecchetto G,Spreafico F,De Salvo GL,Collini P,Jenkner A,Inserra A,Schiavetti A,di Martino M,Casale F

    更新日期:2008-10-01 00:00:00

  • Household material hardship in families of children post-chemotherapy.

    abstract::Poverty is an important patient-reported outcome of therapy and a potential predictor of outcome disparities in pediatric cancer. We previously identified that nearly 30% of pediatric cancer families experience household material hardship (HMH), a concrete measure of poverty including food, energy, or housing insecuri...

    journal_title:Pediatric blood & cancer

    pub_type: 临床试验,杂志文章


    authors: Bilodeau M,Ma C,Al-Sayegh H,Wolfe J,Bona K

    更新日期:2018-01-01 00:00:00

  • Treatment outcome and pattern of failure in hepatoblastoma treated with a consensus protocol in Hong Kong.

    abstract:BACKGROUND AND AIM:We reviewed the results and pattern of failure of the consensus HB/HCC 1996 treatment protocol for pediatric hepatoblastoma (HB) in Hong Kong. The role of SIOPEL and Children's Hepatic tumors International Collaboration (CHIC) risk stratification was evaluated. METHODS:Patients enrolled on the proto...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Liu APY,Ip JJK,Leung AWK,Luk CW,Li CH,Ho KKH,Lo R,Chan EKW,Chan ACY,Chung PHY,Chiang AKS

    更新日期:2019-01-01 00:00:00

  • Second cancer risk in childhood cancer survivors treated with intensity-modulated radiation therapy (IMRT).

    abstract:BACKGROUND:Treatment with radiotherapy (RT) is associated with an increased risk of second malignant neoplasms (SMNs) in childhood cancer survivors; it is unclear how treatment with intensity-modulated radiation therapy (IMRT) impacts this risk. We provide the first report of SMN risk in a cohort of childhood cancer su...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Casey DL,Friedman DN,Moskowitz CS,Hilden PD,Sklar CA,Wexler LH,Wolden SL

    更新日期:2015-02-01 00:00:00

  • Anaphylactoid reaction to high-dose methotrexate and successful desensitization.

    abstract::Anaphylactic/anaphylactoid reaction to methotrexate (MTX) is uncommon. It may occur with the first dose (non-allergic reactions) or after a previous exposure to the drug (allergic or specific reactions). Desensitization has been shown effective in children with allergic-type reactions permitting the continuation of hi...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Oulego-Erroz I,Maneiro-Freire M,Bouzón-Alejandro M,Vázquez-Donsión M,Couselo JM

    更新日期:2010-09-01 00:00:00

  • Management of severe congenital protein C deficiency with a direct oral anticoagulant, edoxaban: A case report.

    abstract::A male patient diagnosed with severe congenital protein C (PC) deficiency during the neonatal period was treated with long-term warfarin but frequently developed purpura fulminans and bleeding. At four years of age, edoxaban was initiated (direct oral anticoagulant [DOAC]). His d-dimer and fibrin/fibrinogen degradatio...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Watanabe K,Arakawa Y,Yanagi M,Isobe K,Mori M,Koh K

    更新日期:2019-06-01 00:00:00

  • A man-made disease: Fetal neonatal alloimmune thrombocytopenia due to incompatibility between oocyte donor and gestational mother.

    abstract::The incompatibility causing fetal and neonatal alloimmune thrombocytopenia (FNAIT) results from a fetus inheriting a paternal human platelet antigen (HPA), which is different from the maternal HPA. We present a unique case of FNAIT in a pregnancy involving an oocyte recipient mother with Turner syndrome. This is the f...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Barg AA,Ifrah AD,Strauss T,Simchen MJ,Orvieto R,Rosenberg N,Kenet G

    更新日期:2017-08-01 00:00:00

  • Hepatoblastoma in patients with molecularly proven familial adenomatous polyposis: Clinical characteristics and rationale for surveillance screening.

    abstract::Familial adenomatous polyposis (FAP) due to APC mutation is associated with an increased risk of hepatoblastoma. All cases of hepatoblastoma in patients with FAP reported in the literature were reviewed. One hundred and nine patients were identified. Thirty-five patients (of 49 with data) were diagnosed with hepatobla...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Trobaugh-Lotrario AD,López-Terrada D,Li P,Feusner JH

    更新日期:2018-08-01 00:00:00

  • Upfront use of gemtuzumab ozogamicin in young children with CD33-positive AML.

    abstract::Gemtuzumab ozogamicin (GO) is a humanized anti-CD33 antibody used for treating patients with CD33+ acute myeloid leukemia (AML). We report three young children (two infants and one toddler) with AML treated with GO 9 mg/m(2). Two received two doses at diagnosis alone with conventional chemotherapy and one received one...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Sayar D,Burstein Y,Bielorai B,Toren A,Dvir R

    更新日期:2010-07-15 00:00:00

  • The Benefits and Challenges of Preconsent in a Multisite, Pediatric Sickle Cell Intervention Trial.

    abstract::Enrollment of patients in sickle cell intervention trials has been challenging due to difficulty in obtaining consent from a legal guardian and lack of collaboration between emergency medicine and hematology. We utilized education and preconsent in a pediatric multisite sickle cell intervention trial to overcome these...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,多中心研究


    authors: Nimmer M,Czachor J,Turner L,Thomas B,Woodford AL,Carpenter K,Gonzalez V,Liem RI,Ellison A,Casper TC,Brousseau DC,sickle cell working group of the Pediatric Emergency Care Applied Research Network (PECARN).

    更新日期:2016-09-01 00:00:00

  • NHL in adolescents and young adults: A unique population.

    abstract::Non-Hodgkin lymphoma (NHL) is a heterogeneous group of lymphoid malignancies with high incidence in adolescents and young adults (AYAs). The most common diseases include diffuse large B-cell lymphoma, anaplastic large cell lymphoma, Burkitt lymphoma, lymphoblastic lymphoma, and primary mediastinal large B-cell lymphom...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章,评审


    authors: Hochberg J,Flower A,Brugieres L,Cairo MS

    更新日期:2018-08-01 00:00:00

  • Brachiocephalic vein for percutaneous ultrasound-guided central line positioning in children: A 20-month preliminary experience with 109 procedures.

    abstract:BACKGROUND:Ultrasound-guided (USG) cannulation of the brachiocephalic vein (BCV) is gaining worldwide consensus for central venous access in children. This study reports a 20-month experience with this approach in children. METHODS:All patients who underwent percutaneous USG central venous catheter (CVC) positioning i...

    journal_title:Pediatric blood & cancer

    pub_type: 杂志文章


    authors: Avanzini S,Mameli L,Disma N,Zanaboni C,Dato A,Montobbio G,Montagnini L,Bevilacqua M,Pierri F,Conte M,Amoroso L,Pala G,Pestarino S,Castagnola E,Molinari AC,Micalizzi C,Morreale G,Mattioli G,Pini Prato A

    更新日期:2017-02-01 00:00:00