Abstract：
:Colonoscopic removal of large, sessile polyps is difficult, but can be successfully carried out by experienced endoscopists. "Piecemeal" resection with an electrocautery snare was performed at our institution in 108 patients with 132 such lesions. The mean size of the unresected polyps was 3.0 cm. Complications occurred in 3.0% of polypectomies (3.8% of patients), with bleeding necessitating transfusion in 2.3% of polypectomies (2.8% of patients), and microperforation (probable) in the remainder. No patient required emergency surgery due to a complication. In 65 patients (60%), colonoscopic resection and follow-up alone was carried out. Of these, adenomas recurred/persisted in 28%, most of which were successfully re-resected. Nearly half of all recurrent polyps occurred after at least one negative intervening examination. Carcinoma later appeared in 17% of the recurrences despite apparent initial complete resection of a previously benign polyp. Cure was ultimately achieved in 88% of endoscopically managed patients. Surgical resection was required in 27% of patients, mostly following the initial polypectomy when invasive carcinoma was found in the specimen. No residual tumor was later found in 41% of the colon specimens from these patients. Ninety-one percent of cancers were favorable stage, whether discovered early or late. Follow-up colonoscopy was achieved in 77% of patients over an average of 3.7 years. Metachronous polyps were excised in 52 patients (63%) and metachronous carcinoma was diagnosed in 3 patients (3.6%). An aggressive regimen of surveillance colonoscopy is warranted in these patients to detect and manage local recurrences and to remove subsequent adenomas. Endoscopic resection of large sessile adenomas can be safe and effective.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Walsh RM,Ackroyd FW,Shellito PCdoi
10.1016/s0016-5107(92)70421-0keywords:
subject
Has Abstractpub_date
1992-05-01 00:00:00pages
303-9issue
3eissn
0016-5107issn
1097-6779pii
S0016-5107(92)70421-0journal_volume
38pub_type
杂志文章abstract：BACKGROUND:Lymphangiohemangioma, also called lymphatic-venous or venolymphatic malformation, is a rare malformation of the lymphatics, with vascular elements. These are low-flow vascular lesions. OBJECTIVE:To evaluate the feasibility and efficacy of endoscopic injection sclerotherapy with doxycycline for low-flow vasc...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2007.06.023
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:New therapies are needed for pancreatic cancer. OBJECTIVE:To determine the feasibility and safety of a new endoscopic treatment. Secondary endpoints were to determine effects on tumor growth measured with CT scan and to find the overall survival. DESIGN:A cohort study of patients with local progression of ...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1016/j.gie.2012.08.006
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Although traditional transoral outlet reduction (TORe) involves argon plasma coagulation (APC) before endoscopic suturing, modified endoscopic submucosal dissection (ESD) has also been used. This study aims to evaluate the safety and efficacy of modified ESD-TORe in comparison with traditional APC-T...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2020.01.036
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Uncovered, rather than covered, metal stents are commonly used for palliation of malignant gastric outlet obstruction because of the low risk of stent migration, but tumor ingrowth risk is a major drawback. Few reports address malignant obstruction after gastric surgery. OBJECTIVE:Our purpose was to compare...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.08.030
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Many options are available for palliation of inoperable malignant stenoses of the esophagus. We report our experience with different modalities of endoscopic therapy. METHODS:From 1986 to 1996, we treated 125 patients with dysphagia caused by unresectable malignant tumors with endoscopic therapy. Seventy pa...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(98)70007-0
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND AND AIMS:EUS-guided liver biopsy sampling using FNA and, more recently, fine-needle biopsy (FNB) needles has been reported with discrepant diagnostic accuracy, in part due to differences in methodology. We aimed to compare liver histologic yields of 4 EUS-based needles and 2 percutaneous needles to identify ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2016.07.065
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Although total obstruction or secondary atresia of the esophagus is extremely rare, high-grade strictures are not uncommon. The retrograde approach was previously described to achieve dilation when the conventional antegrade method fails. SETTING:Gastroenterology laboratory in a tertiary referral center. P...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.08.008
更新日期：2007-02-01 00:00:00
abstract：BACKGROUND:EUS is a promising modality for pancreatic-cancer screening in high-risk persons, including familial pancreatic-cancer (FPC) kindreds. OBJECTIVE:To assess interobserver agreement for interpretation of EUS in persons at high risk for pancreatic cancer. DESIGN:Seventeen expert endosonographers blinded to pat...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.09.018
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:The long-term efficacy of sequential insertion of multiple plastic stents for benign biliary strictures is poorly defined. The aims of this study were to evaluate the long-term outcome (bile duct patency, complications) of this therapy and to identify predictors of a good outcome. METHODS:Retrospective revi...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2002.122955
更新日期：2002-05-01 00:00:00
abstract：:Endosonography was performed in 76 patients who had endoscopically detected gastroesophageal varices or questionable submucosal lesions, or who were being evaluated for pancreatic carcinoma or pancreatitis. The result were compared with surgery or autopsy results. The patients were divided retrospectively into four gr...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(95)70071-4
更新日期：1995-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Split-dose bowel preparation for colonoscopy results in superior preparation quality. However, some endoscopy units remain hesitant to prescribe split-dose preparation given theoretical concerns about possible aspiration caused by gastric residual fluid when a second dose is given close to the time ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2015.08.081
更新日期：2016-03-01 00:00:00
abstract：:Thirty patients with upper gastrointestinal bleeding due to a Mallory-Weiss tear were diagnosed by endoscopy. Seventeen patients had stopped bleeding spontaneously, and 13 were actively bleeding when examined. Ten of these 13 were successfully electrocoagulated with cessation of bleeding without morbidity or mortality...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(80)73301-1
更新日期：1980-11-01 00:00:00
abstract：BACKGROUND AND AIMS:Protruding lesions of the small bowel vary in wireless capsule endoscopy (WCE) images, and their automatic detection may be difficult. We aimed to develop and test a deep learning-based system to automatically detect protruding lesions of various types in WCE images. METHODS:We trained a deep convo...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2020.01.054
更新日期：2020-07-01 00:00:00
abstract：:Fifty cirrhotic patients with esophageal varices underwent endoscopic treatment in a prospective randomized trial carried out to compare variceal ligation with injection sclerotherapy, with respect to safety, efficacy, and complications in the initial session. Twenty-five patients each were treated using endoscopic va...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0016-5107(93)70050-4
更新日期：1993-03-01 00:00:00
abstract：BACKGROUND:Pentoxifylline can ameliorate pancreatitis in animal models because of its anti-tumor necrosis factor properties. OBJECTIVE:Our purpose was to study the safety and efficacy of pentoxifylline in the prevention of post-ERCP pancreatitis. DESIGN:Patients due to undergo ERCP for various indications were random...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2007.03.1045
更新日期：2007-09-01 00:00:00
abstract：BACKGROUND:Routine endoscopic mucosal biopsies are generally considered safe. However, the outcomes of performing large numbers of biopsies in subjects enrolled in research protocols have not been reported. OBJECTIVE:Our purpose was to assess the safety of taking numerous mucosal biopsy specimens during endoscopic pro...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2008.05.015
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:EUS-FNA can be used to accurately diagnose and stage GI and pulmonary neoplasms. This study evaluated the performance characteristics of a new compact linear EUS system during EUS-FNA. METHODS:A total of 37 patients enrolled in this prospective pilot study underwent clinically indicated EUS-FNA and/or celia...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(03)70038-8
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Retrograde double-balloon enteroscopy (rDBE) is technically a different procedure from its antegrade counterpart. Its unique indications, success rate, and learning curve have not been specifically reported. OBJECTIVE:To examine technical issues specific to the rDBE approach. DESIGN:Retrospective review. ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.12.038
更新日期：2007-04-01 00:00:00
abstract：:Twenty patients undergoing clinically indicated elective colonoscopy were prospectively monitored noninvasively for alterations in cardiorespiratory function. Most of the patients were elderly and many had either cardiac or pulmonary disease. All subjects were premedicated with intramuscular meperidine and continuousl...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(89)72764-4
更新日期：1989-05-01 00:00:00
abstract：BACKGROUND:A combination of midazolam and opioid is usually used to achieve sedation and analgesia during colonoscopy. Two commonly used opioids are meperidine and fentanyl, but few studies have compared their efficacy. OBJECTIVE:This randomized trial aimed to compare the efficacy and recovery time of 2 sedation regim...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2008.09.033
更新日期：2009-03-01 00:00:00
abstract：:We investigated the endoscopic and histologic features of 74 nonpolypoid neoplasias of the colorectum measuring 15 mm or less in diameter. Colonoscopically, they were characterized by flat growth, being either slightly elevated with a central depression or else completely flat against the surrounding mucosa. Of the 54...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(05)80595-4
更新日期：1995-02-01 00:00:00
abstract：BACKGROUND:Celiac disease (CD) is a gluten-dependent enteropathy. The current standard for diagnosing CD involves obtaining 4 biopsy samples from the descending duodenum. It has been suggested that duodenal bulb biopsies may also be useful. OBJECTIVE:To assess the utility of bulbar biopsies for the diagnosis of CD in ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2010.05.021
更新日期：2010-09-01 00:00:00
abstract：:We compared the results of ultrasonically guided fine needle aspiration biopsy and laparoscopy in 63 patients who underwent both procedures. In this series, fine needle biopsy showed a sensitivity of 75.6% with a 84.1% overall accuracy. Laparoscopy demonstrated a 74.3% sensitivity with an overall accuracy of 82.7%. Th...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(88)71318-8
更新日期：1988-05-01 00:00:00
abstract：BACKGROUND:Although the early use of a risk stratification score in upper GI bleeding is recommended, existing risk scores are not widely used in clinical practice. OBJECTIVE:We sought to develop and validate an easily calculated bedside risk score, AIMS65, by using data routinely available at initial evaluation. DES...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.gie.2011.06.024
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:A histopathologic diagnosis of metastasis in enlarged mediastinal lymph nodes usually results in non-surgical management. Cytologic specimens obtained by EUS-guided FNA can be used to detect malignancy in posterior mediastinal lymph nodes. The purpose of this study was to determine the rate of thoracic surge...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(04)01709-2
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:Use of colonoscopy is thought to reduce colorectal cancer (CRC) mortality, but its impact at the population level is unclear. OBJECTIVE:To estimate the effect of current colonoscopy use on CRC mortality and its further potential in reducing CRC mortality. DESIGN:Population-level analysis was performed by u...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2010.12.005
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND AND AIMS:Early neoplasia in Barrett's esophagus (BE) can be effectively and safely removed by endoscopic resection (ER) using multiband mucosectomy (MBM). This study aimed to document performance of a novel MBM device designed for improved visualization, easier passage of accessories, and better suction powe...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.gie.2018.06.030
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Little is known about gastric neoplasms arising from hyperplastic polyps (HPs). OBJECTIVE:To investigate the risk factors associated with neoplasms within HPs and to evaluate the role of alterations of the p16-cyclin D1-pRb pathway in the malignant transformation of HPs. DESIGN:Retrospective, case-control ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2014.04.020
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Biliary tract malignancies can be assessed with either EUS or SpyGlass cholangioscopy (SGC). OBJECTIVE:To evaluate the impact of EUS and guided biopsy before considering SGC in patients who had biliary strictures with negative ductal brushing. DESIGN:Prospective, observational study. SETTING:Tertiary leve...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2013.05.020
更新日期：2013-12-01 00:00:00
abstract：:Twenty patients with dysphagia due to inoperable esophageal cancer were randomized to receive either contact or noncontact endoscopic laser treatment. Treatment groups were similar with respect to age, dysphagia score, and tumor dimensions. The median number of initial treatment sessions was two in both groups, and th...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0016-5107(89)72842-x
更新日期：1989-09-01 00:00:00
