Abstract:
BACKGROUND AND AIMS:EUS-guided liver biopsy sampling using FNA and, more recently, fine-needle biopsy (FNB) needles has been reported with discrepant diagnostic accuracy, in part due to differences in methodology. We aimed to compare liver histologic yields of 4 EUS-based needles and 2 percutaneous needles to identify optimal number of needle passes and suction. METHODS:Six needle types were tested on human cadaveric tissue: one 19G FNA needle, one existing 19G FNB needle, one novel 19G FNB needle, one 22G FNB needle, and two 18G percutaneous needles (18G1 and 18G2). Two needle excursion patterns (1 vs 3 fanning passes) were performed on all EUS needles. Primary outcome was number of portal tracts. Secondary outcomes were degree of fragmentation and specimen adequacy. Pairwise comparisons were performed using t tests, with a 2-sided P < .05 considered to be significant. Multivariable regression analysis was performed. RESULTS:In total, 288 liver biopsy samplings (48 per needle type) were performed. The novel 19G FNB needle had significantly increased mean portal tracts compared with all needle types. The 22G FNB needle had significantly increased portal tracts compared with the 18G1 needle (3.8 vs 2.5, P < .001) and was not statistically different from the 18G2 needle (3.8 vs 3.5, P = .68). FNB needles (P < .001) and 3 fanning passes (P ≤ .001) were independent predictors of the number of portal tracts. CONCLUSIONS:A novel 19G EUS-guided liver biopsy needle provides superior histologic yield compared with 18G percutaneous needles and existing 19G FNA and core needles. Moreover, the 22G FNB needle may be adequate for liver biopsy sampling. Investigations are underway to determine whether these results can be replicated in a clinical setting.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Schulman AR,Thompson CC,Odze R,Chan WW,Ryou Mdoi
10.1016/j.gie.2016.07.065subject
Has Abstractpub_date
2017-02-01 00:00:00pages
419-426issue
2eissn
0016-5107issn
1097-6779pii
S0016-5107(16)30469-2journal_volume
85pub_type
杂志文章abstract:BACKGROUND:The role of Helicobacter pylori in patients with cirrhosis and increased prevalence of peptic ulcers is still poorly defined. The objective is to evaluate the effect of H pylori eradication on ulcer recurrence in patients with cirrhosis. METHODS:The study was conducted at a single, tertiary, referral hospit...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(05)01633-0
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Endoscopic resection of large colorectal lesions is associated with high complication rates. OBJECTIVE:To evaluate the effect of prophylactic clip closure of polypectomy sites after resection of large (≥2 cm) sessile and flat colorectal lesions. DESIGN:Retrospective study. SETTING:Tertiary referral center...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2012.10.024
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Capsule endoscopy allows the direct visualization of the entire small bowel. There is limited data on the clinical significance of permanent capsule retention. OBJECTIVE:Our purpose was to document the frequency, findings, risk factors, management, and outcomes of permanent capsule retention. DESIGN:Retros...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2006.02.036
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND AND AIMS:An increasing number of patients are undergoing GI endoscopic procedures with active prescriptions for direct oral anticoagulants (DOACs). DOACs have been associated with a higher risk of GI bleeding (GIB) compared with warfarin. Our aims were to compare the risk of postendoscopic GIB and thromboemb...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2020.02.038
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Confocal laser endomicroscopy (CLE) may be used to diagnose gastric cancer and intestinal metaplasia, but the impact of CLE experience on the accuracy of confocal diagnosis of gastric cancer and intestinal metaplasia is not clear. OBJECTIVE:To establish the sensitivity, specificity, and intragroup interobse...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2011.01.068
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Acute nonvariceal upper-GI hemorrhage (NVUGIH) is associated with significant morbidity and mortality. OBJECTIVE:To examine the relationship between hospital volume and outcomes of NVUGIH. DESIGN:A cross-sectional study. SETTING:Participating hospitals from the Nationwide Inpatient Sample 2004. PATIENTS:...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.12.061
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) is the standard of care for treating gastric intramucosal neoplasias in Japan. However, it is seldom performed in Western countries, mainly because it is technically very challenging. Several traction methods have been proposed to facilitate submucosal dissection, but t...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2011.07.037
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:EUS-guided celiac plexus neurolysis (EUS-CPN) improves pain control in patients with pancreatic cancer. EUS allows visualization of the celiac ganglion. OBJECTIVE:To determine predictors of response to EUS-CPN in a cohort of 64 patients with pancreatic malignancy. DESIGN:Retrospective analysis of prospecti...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2010.10.029
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Transgastric flexible endoscopic anastomosis might offer advantages over open and laparoscopic surgery, especially for bariatrics or patients with obstructive malignancy. OBJECTIVE:To develop methods for performing transgastric anastomosis. DESIGN/RESULTS:Twelve gastrojejunal anastomoses were formed in pig...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2005.09.035
更新日期:2006-02-01 00:00:00
abstract::A study of selective sedation for colonoscopy was conducted in two parts. All procedures were performed by one experienced colonoscopist. In the first phase, 41 patients received intravenous sedation before colonoscopy and were then prospectively randomized to either a "not-reversed" group, which did not receive fluma...
journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1994-11-01 00:00:00
abstract:BACKGROUND:Routine endoscopic mucosal biopsies are generally considered safe. However, the outcomes of performing large numbers of biopsies in subjects enrolled in research protocols have not been reported. OBJECTIVE:Our purpose was to assess the safety of taking numerous mucosal biopsy specimens during endoscopic pro...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.05.015
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Endoscopic abnormalities have been described in adult patients with celiac disease that may suggest the diagnosis, especially when the presentation is atypical. METHODS:The duodenum of 140 children undergoing EGD for various different indications was evaluated macroscopically and histologically. RESULTS:Hi...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2001.119217
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Duodenal diverticulum (DD) is a rare cause of upper-GI bleeding. The diagnosis and treatment of DD bleeding (DDB) is challenging. Surgical management was the mainstay of therapy before the 1990s. OBJECTIVE:To evaluate the clinical feature, diagnosis, and management of cases of DDB at our institution and the...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,评审
doi:10.1016/j.gie.2007.06.001
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:This study was designed to demonstrate the efficacy and safety of a novel endoscopic full-thickness plication device for the treatment of GERD. METHODS:Gastric pressures and reflux from the gastroesophageal junction were measured in 20 excised pig stomachs before and after full-thickness plication within 1 ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2002.125250
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Preoperative diagnosis of solid pancreatic lesions remains challenging despite advancement in imaging technologies. EUS has the benefit of being a minimally invasive, well-tolerated procedure, although results are operator-dependent. The addition of FNA (EUS-guided FNA) provides samples for cytopathologic an...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,meta分析
doi:10.1016/j.gie.2011.08.049
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Diagnostic natural-orifice transluminal endoscopic surgery (NOTES) peritoneoscopy can easily be performed with standard endoscopic equipment in animal studies. The efficacy and optimal transgastric site for NOTES access in humans, however, has not been determined. OBJECTIVE:To characterize the efficacy of v...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2010.03.1070
更新日期:2010-08-01 00:00:00
abstract::Twenty patients with dysphagia due to inoperable esophageal cancer were randomized to receive either contact or noncontact endoscopic laser treatment. Treatment groups were similar with respect to age, dysphagia score, and tumor dimensions. The median number of initial treatment sessions was two in both groups, and th...
journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0016-5107(89)72842-x
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND AND AIMS:Right aberrant hepatic ducts are an anatomic variant with clinical relevance because of the risk of injury during cholecystectomy. Treatment options for aberrant hepatic duct injuries are not standardized. This study aims to analyze the long-term results of endoscopic treatment of aberrant hepatic d...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2019.09.043
更新日期:2020-03-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2005.08.042
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:A recent American Society for Gastrointestinal Endoscopy Technology Status Evaluation Report recommended comparative studies of water-aided colonoscopy methods to refine the optimal insertion technique. OBJECTIVE:Air insufflation (AI), water immersion (WI), and water exchange (WE) were compared head-to-head...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.gie.2014.07.029
更新日期:2015-03-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2012.01.046
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The diagnostic yield of EUS-guided FNA (EUS-FNA) of solid pancreatic masses is a potential benchmark for EUS-FNA quality, because the majority of EUS-FNA of solid pancreatic masses should be diagnostic for malignancy. OBJECTIVES:To determine the cytologic diagnostic rate of malignancy in EUS-FNA of solid pa...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,多中心研究
doi:10.1016/j.gie.2007.01.017
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Video capsule endoscopy (VCE) is most commonly performed in the outpatient setting to evaluate obscure GI bleeding. OBJECTIVE:To determine the impact of gender and inpatient status on VCE findings. DESIGN:Retrospective study. SETTING:Two tertiary medical centers and a VA medical center. PATIENTS:A total ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2011.07.019
更新日期:2011-11-01 00:00:00
abstract::This prospective study compares the accuracy of barium enema examination performed by experienced radiologists to colonoscopy performed by experienced gastroenterologists blinded to the radiographic findings to detect proximal, synchronous lesions in patients with polyps detected during fiberoptic sigmoidoscopy. Three...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(91)70822-5
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:Detailed imaging of the common bile duct and main pancreatic duct is possible with endosonography. Utilizing a custom manufactured flexible needle, we have developed a technique of performing endosonography-guided cholangiopancreatography (EGCP). METHODS:Of 205 patients undergoing ERCP, complete ductography...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(06)80108-2
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:Endoscopic submucosal dissection (ESD) is a well-accepted method for removing superficial mucosal tumors; however, there is limited data on the use of this method for removing subepithelial tumors. OBJECTIVE:To investigate the efficacy, safety, and outcome of ESD for gastric subepithelial tumors and determi...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2011.08.029
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:EUS-guided biliary drainage (EUS-BD) has emerged as an alternative rescue method in patients with failed ERCP. Opportunities for teaching and training are limited because of a low case volume at most centers. OBJECTIVE:To evaluate a stereolithography/3-dimensional (3D) printing bile duct prototype for teach...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2014.09.011
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND AND AIMS:In chronic pancreatitis (CP), fibrotic pancreatic duct (PD) strictures pose a therapeutic challenge, because endoscopic dilatation requires multiple procedures with suboptimal results. Biodegradable self-expandable stents (BD-SESs) may serve as an alternative in this setting. METHODS:Patients with ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2017.08.018
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the effectiveness of endoscopic sphincterotomy for preoperative and postoperative complications of hepatic hydatid disease. METHODS:Nineteen patients underwent endoscopic treatment for complications of hepatic hydatid disease. Indications for ERCP in 5 patients treated ...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2001.118256
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Preoperative radiologic localization of insulinomas often fails because of the small size of these tumors. Endoscopic ultrasound (EUS) can localize insulinomas in up to 80% of the cases. The aim of this study was to compare EUS and computed tomography (CT) diagnostic accuracy for insulinomas. METHODS:We rev...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(00)70288-4
更新日期:2000-05-01 00:00:00