当前位置： SCI文献检索 > JOURNAL OF CLINICAL PERIODONTOLOGY期刊下所有文献 > Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers.

Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers.

Abstract：

OBJECTIVES:This study investigates the effect of a range of potential risk factors on the severity of gingival overgrowth in transplant patients medicated with ciclosporin in the absence of any calcium channel blockers. MATERIALS AND METHODS:One hundred dentate solid organ transplants medicated with ciclosporin (but not calcium channel blockers or phenytoin) were recruited for the study. Demographic, pharmacological and periodontal data were recorded and gingival overgrowth assessed from stone models. RESULTS:Univariate analysis identified the duration of transplant, papilla bleeding index, creatinine serum concentration, azathioprine and prednisolone dosage as risk factors for overgrowth severity. Multivariate modelling, excluding the periodontal parameters, gave a predictive model that included dosages of ciclosporin, azathioprine, prednisolone and weight (p<0.0001, adjusted-R2=19%). Adding the periodontal variables strengthened the model (p<0.0001, adjusted-R2=34.5%). CONCLUSION:The explanatory models in this study contain a number of variables that moderate inflammation (azathioprine and prednisolone) or are markers of it (papilla bleeding index). Dosage of each of the three immunosuppressants was identified as a risk factor for the severity of gingival change. This observation appears to have been masked by the effects of the calcium channel blockers in earlier studies.

journal_name

J Clin Periodontol

journal_title

Journal of clinical periodontology

authors

Thomason JM,Seymour RA,Ellis JS

doi

10.1111/j.1600-051X.2005.00657.x

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

273-9

issue

3

eissn

0303-6979

issn

1600-051X

pii

CPE657

journal_volume

32

pub_type

杂志文章

相关文献

JOURNAL OF CLINICAL PERIODONTOLOGY文献大全
  • Oral health and changes in lipid profile: A nationwide cohort study.

    abstract：AIM:We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. MATERIALS AND METHODS:We included nationwide health screening program participants who underwent oral health examination in...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.13373

    authors： Song TJ,Kim JW,Kim J

    更新日期：2020-12-01 00:00:00

  • Effect of 3 dentifrices containing triclosan and various additives. An experimental gingivitis study.

    abstract：BACKGROUND:The antiplaque and antigingivitis effect of 3 dentifrices was evaluated using the 21-day partial-mouth experimental model of gingivitis. METHOD:25 volunteers took part in this cross-over, double-blind study, carried out in 4 phases of 21 days each. For each phase of the study, a toothshield of the IV quadra...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1034/j.1600-051x.2000.027007494.x

    authors： Nogueira-Filho GR,Toledo S,Cury JA

    更新日期：2000-07-01 00:00:00

  • The use of metronidazole and amoxicillin in the treatment of advanced periodontal disease. A prospective, controlled clinical trial.

    abstract：:The present clinical trial was performed to study the effect of systemic administration of metronidazole and amoxicillin as an adjunct to mechanical therapy in patients with advanced periodontal disease. 16 individuals, 10 female and 6 male, aged 35-58 years, with advanced periodontal disease were recruited. A baselin...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-051x.1998.tb02455.x

    authors： Berglundh T,Krok L,Liljenberg B,Westfelt E,Serino G,Lindhe J

    更新日期：1998-05-01 00:00:00

  • Ridge regeneration of damaged extraction sockets using rhBMP-2: an experimental study in canine.

    abstract：OBJECTIVES:This study evaluated the dimensional ridge alteration in a buccal-bone-deficient extraction socket, and ridge regeneration following socket grafting accompanied by recombinant human bone morphogenetic protein 2 (rhBMP-2) or a collagen membrane covering. MATERIAL AND METHODS:In five beagle dogs, entire bucca...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.12414

    authors： Lee JS,Jung JS,Im GI,Kim BS,Cho KS,Kim CS

    更新日期：2015-07-01 00:00:00

  • Periodontal diseases and depression: A preclinical in vivo study.

    abstract：AIM:To analyse, through a pre-clinical in vivo model, the possible mechanisms linking depression and periodontitis at behavioural, microbiological and molecular levels. MATERIALS AND METHODS:Periodontitis (P) was induced in Wistar:Han rats (oral gavages with Porphyromonas gingivalis and Fusobacterium nucleatum) during...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.13420

    authors： Martínez M,Martín-Hernández D,Virto L,MacDowell KS,Montero E,González-Bris Á,Marín MJ,Ambrosio N,Herrera D,Leza JC,Sanz M,García-Bueno B,Figuero E

    更新日期：2021-01-12 00:00:00

  • Periodontal conditions, remaining teeth and oral hygiene habits in a group of Vietnamese refugees in Norway.

    abstract：:Since 1975, about 3500 Vietnamese refugees have come to Norway. The purpose of the present study was to report on remaining teeth and periodontal conditions in a population of 200 adolescent and adult Vietnamese refugees. The mean number of remaining teeth ranged from 27.8 in the youngest age group to 24.6 in the olde...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1985.tb01352.x

    authors： Selikowitz HS,Gjermo P

    更新日期：1985-01-01 00:00:00

  • Computer-assisted densitometric image analysis (CADIA) for the assessment of alveolar bone density changes in furcations.

    abstract：:The purpose of this study was to test the applicability of computer-assisted densitometric image analysis (CADIA) for the quantitative assessment of alveolar bone density changes in furcations of multirooted teeth. In 21 patients, standardized radiographs were obtained immediately after and at 1, 6 and 12 months after...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1989.tb01611.x

    authors： Bräegger U,Pasquali L,Weber H,Kornman KS

    更新日期：1989-01-01 00:00:00

  • Comparison of periodontal disease in HIV seropositive subjects and controls (I). Clinical features.

    abstract：:The aims of this study were to investigate the prevalence and severity of periodontal diseases in HIV seropositive and assumed HIV seronegative individuals in the Edinburgh area. 29 HIV seropositive subjects were examined at baseline and at 3-monthly intervals. Attachment loss and dichotomous indicators of periodontal...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1995.tb00805.x

    authors： Smith GL,Cross DL,Wray D

    更新日期：1995-07-01 00:00:00

  • Eruption cyst formation associated with cyclosporin A.

    abstract：BACKGROUND:Cyclosporin A (CyA) is a potent immunomodulatory agent with a wide range of applications. Despite its therapeutic value, multiple adverse effects of CyA have been identified. This case report describes eruption cyst formation as a possible adverse effect of CyA administration during tooth eruption in a boy t...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2003.02028.x

    authors： Kuczek A,Beikler T,Herbst H,Flemmig TF

    更新日期：2003-05-01 00:00:00

  • Prevalence and distribution of bone defects in moderate and advanced adult periodontitis.

    abstract：:The purpose of the present investigation was to evaluate the prevalence and distribution of different forms of bone defects using direct observation during periodontal surgery. 286 patients with moderate or advanced adult periodontitis diagnosed during clinical and radiographic examination provided a sample of 5476 te...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.1999.260108.x

    authors： Vrotsos JA,Parashis AO,Theofanatos GD,Smulow JB

    更新日期：1999-01-01 00:00:00

  • Essential oil mouthwashes: a key component in oral health management.

    abstract：:This Supplement provides clear evidence that essential oil (EO) mouthwashes can be a beneficial, safe component of daily oral health routines. However, despite the wealth of supporting evidence, several issues are worthy of discussion. Patient compliance is a clear issue with oral home-care routines, and the emphasis ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.30.s5.8.x

    authors： Claffey N

    更新日期：2003-01-01 00:00:00

  • Comparison of the plaque removal efficacy of a new flossing aid (Quik Floss) to finger flossing.

    abstract：:The purpose of this clinical trial was to compare the effectiveness and safety of a new dental flossing device (Quik Floss) to finger flossing in plaque removal, reduction of gingival inflammation and patient preference. 30 healthy, non-flossing adults with 20 natural teeth, a plaque index (PI) of at least 1.8 and a g...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-051x.1996.tb00626.x

    authors： Carter-Hanson C,Gadbury-Amyot C,Killoy W

    更新日期：1996-09-01 00:00:00

  • Keratinized tissue gain after free gingival graft augmentation procedures around teeth and dental implants: A prospective observational study.

    abstract：AIM:The primary goal was to compare the amount of keratinized tissue width (KTW) gain after free gingival graft (FGG) procedures around implants and teeth after 6 and 12 months of healing. MATERIALS AND METHODS:Patients with mucogingival defects (<2 mm of KT) around teeth and implants underwent a gingival augmentation...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.13394

    authors： Golmayo P,Barallat L,Losada M,Valles C,Nart J,Pascual-La Rocca A

    更新日期：2021-02-01 00:00:00

  • Efficacy of a prototype brush head for a powered toothbrush. A multicentre study.

    abstract：PRIMARY OBJECTIVE:To evaluate a multicentre clinical trial design for testing powered toothbrushes. SECONDARY OBJECTIVE:To compare the efficacy of a prototype brush head (N2.3) for the Philips Jordan Sensiflex 2000 powered toothbrush (PTB) to that of Braun Oral-B D15 PTB in removing dental plaque MATERIAL AND METHODS...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1034/j.1600-051x.2002.291003.x

    authors： McCracken GI,Chapple IL,Milward M,Steen N,DeJager M,Heasman PA

    更新日期：2002-10-01 00:00:00

  • Exposure measurement in the association between periodontal disease and prematurity/low birth weight.

    abstract：AIM:To compare the use of different definitions for exposure measurement in cases of association between periodontal disease (PD) and prematurity and/or low birth weight (PLBW). MATERIAL AND METHODS:A database from a previous case-control study was used to compare four different definitions for periodontitis: at least...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2007.01141.x

    authors： Gomes-Filho IS,Cruz SS,Rezende EJ,Dos Santos CA,Soledade KR,Magalhães MA,de Azevedo AC,Trindade SC,Vianna MI,Passos Jde S,Cerqueira EM

    更新日期：2007-11-01 00:00:00

  • The involvement of nervous and some inflammatory response mechanisms in the acute snuff-induced gingival hyperaemia in humans.

    abstract：BACKGROUND AND AIM:Tobacco users and especially cigarette smokers are at higher risk than non-smokers for periodontal disease. The pathogenic mechanism has been proposed to be the vasoconstrictive properties of nicotine, with reduced gingival blood flow (GBF) as a contributing factor in the development of periodontal d...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2002.290911.x

    authors： Mavropoulos A,Aars H,Brodin P

    更新日期：2002-09-01 00:00:00

  • Meta-analysis of the effect of scaling and root planing, surgical treatment and antibiotic therapies on periodontal probing depth and attachment loss.

    abstract：OBJECTIVE:This paper reports a meta-analysis of studies that have investigated the effect of scaling and root planing on periodontal probing depth and attachment loss. MATERIAL AND METHODS:The criteria used for inclusion of studies were as follows: root planing and scaling alone was one of the primary treatment arms; ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,meta分析

    doi：10.1034/j.1600-051x.2002.291102.x

    authors： Hung HC,Douglass CW

    更新日期：2002-11-01 00:00:00

  • The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis-A randomized clinical trial.

    abstract：AIM:To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral halitosis. MATERIALS AND METHODS:Forty-six adults with intra-oral halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral halitosis was ev...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jcpe.12779

    authors： Erovic Ademovski S,Mårtensson C,Persson GR,Renvert S

    更新日期：2017-10-01 00:00:00

  • The comparative effect of acidified sodium chlorite and chlorhexidine mouthrinses on plaque regrowth and salivary bacterial counts.

    abstract：:Acidified sodium chlorite (ASC) is recognised as a highly potent, broad spectrum antimicrobial system that has been successfully developed for uses in veterinary, food processing and medical device fields. The current studies aimed to investigate the persistence of antimicrobial action and plaque inhibitory properties...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-051x.1997.tb00236.x

    authors： Yates R,Moran J,Addy M,Mullan PJ,Wade WG,Newcombe R

    更新日期：1997-09-01 00:00:00

  • A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years.

    abstract：OBJECTIVE:To systematically review the incidence of biological and technical complications in implant therapy reported in prospective longitudinal studies of at least 5 years. METHODS:A MEDLINE search was conducted for prospective longitudinal studies with follow-up periods of at least 5 years. Screening and data abst...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1034/j.1600-051x.29.s3.12.x

    authors： Berglundh T,Persson L,Klinge B

    更新日期：2002-01-01 00:00:00

  • Periodontal status in insulin-dependent diabetic adolescents.

    abstract：:A cross-sectional study was designed to evaluate the periodontal status of 85 12-18 year-old French adolescents with insulin-dependent diabetes (IDDM) and 38 healthy controls in the same age group. The clinical examination consisted of plaque control and gingival inflammation evaluation and probing attachment level. T...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1992.tb01710.x

    authors： de Pommereau V,Dargent-Paré C,Robert JJ,Brion M

    更新日期：1992-10-01 00:00:00

  • Prevalence of periodontitis in an adult population from an urban area in North Italy: findings from a cross-sectional population-based epidemiological survey.

    abstract：AIM:There is a paucity of up-to-date data regarding prevalence and risk indicators of periodontitis in Italy. Therefore, the aim of this study was to evaluate the prevalence of periodontitis and its risk indicators among adults from an urban area in North Italy. MATERIAL AND METHODS:This cross-sectional survey used a ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.12420

    authors： Aimetti M,Perotto S,Castiglione A,Mariani GM,Ferrarotti F,Romano F

    更新日期：2015-07-01 00:00:00

  • Probing pocket depth at mobile/nonmobile teeth.

    abstract：:The aim of the present investigation was to study the influence of an increased tooth mobility on the resistance offered by the periodontal tissues to probing. 6 beagle dogs were used. At the start of the experiment, the animals had clean teeth and normal gingival and periodontal conditions. In each dog, a device was ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1992.tb02166.x

    authors： Neiderud AM,Ericsson I,Lindhe J

    更新日期：1992-11-01 00:00:00

  • Periodontal infection as a possible severity factor for rheumatoid arthritis.

    abstract：OBJECTIVE:Clinical effects of periodontal treatment on biochemical and clinical markers of disease severity in rheumatoid arthritis (RA) patients with periodontal disease were evaluated. METHODS:Forty-two patients were assigned to two groups, G1 (n=16) and G2 (n=26). G1 patients were submitted to oral hygiene instruct...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章

    doi：10.1111/j.1600-051X.2005.00689.x

    authors： Ribeiro J,Leão A,Novaes AB

    更新日期：2005-04-01 00:00:00

  • A systematic review of the effectiveness of self-performed mechanical plaque removal in adults with gingivitis using a manual toothbrush.

    abstract：OBJECTIVE:To assess the effectiveness of self-performed mechanical plaque removal in adults with gingivitis using a manual toothbrush with respect to the level of plaque and gingivitis in controlled studies of at least 6 months duration. SEARCH: Medline-PubMed up to and including September 2004. RESULTS:Out of 3223 ti...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1111/j.1600-051X.2005.00795.x

    authors： van der Weijden GA,Hioe KP

    更新日期：2005-01-01 00:00:00

  • Lactate dehydrogenase activity in gingival crevicular fluid collected with filter paper strips: analysis in subjects with non-inflamed and mildly inflamed gingiva.

    abstract：:A previous study of lactate dehydrogenase (LDH) in gingival crevicular fluid (GCF) suggested that the concentration is 10 to 25 times that of serum (means = 2300 international units/1 versus 100 IU/1 for serum). That study used capillary tubes to collect microliter amounts of GCF. Since invasive collection techniques ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1985.tb01374.x

    authors： Lamster IB,Mandella RD,Gordon JM

    更新日期：1985-02-01 00:00:00

  • Pleiotropic effects of vitamin D3 on CD4+ T lymphocytes mediated by human periodontal ligament cells and inflammatory environment.

    abstract：AIMS:Both, vitamin D3 and human periodontal ligament cells (hPDLCs) possess immunosuppressive properties, but their combined effect on immune cells has never been investigated. Here, we analysed the impact of vitamin D3 on the immunosuppressive properties of hPDLCs towards CD4+ T lymphocytes. MATERIAL AND METHODS:Allo...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.13283

    authors： Behm C,Blufstein A,Gahn J,Kubin B,Moritz A,Rausch-Fan X,Andrukhov O

    更新日期：2020-06-01 00:00:00

  • Detection of high-risk groups and individuals for periodontal diseases: laboratory markers based on the microbiological analysis of subgingival plaque.

    abstract：:Periodontal microbiology is reviewed with regard to the potential of certain characteristics to serve as markers of high risk groups or individuals for periodontal diseases. The generally accepted associations between particular organisms and the various periodontal diseases are discussed. The usefulness of various cl...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1600-051x.1990.tb01040.x

    authors： Maiden MF,Carman RJ,Curtis MA,Gillett IR,Griffiths GS,Sterne JA,Wilton JM,Johnson NW

    更新日期：1990-01-01 00:00:00

  • Chemiluminescent assay of alkaline phosphatase in human gingival crevicular fluid: investigations with an experimental gingivitis model and studies on the source of the enzyme within crevicular fluid.

    abstract：:The purpose of this study was to investigate how levels of gingival crevicular fluid (GCF) alkaline phosphatase (ALP) change in relation to levels of plaque and gingival inflammation in 20 adults during a 21 day period of experimental gingivitis. The source of ALP within GCF was also investigated using a repeat sampli...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1996.tb01829.x

    authors： Chapple IL,Socransky SS,Dibart S,Glenwright HD,Matthews JB

    更新日期：1996-06-01 00:00:00

  • Assessment of pain in cervical dentinal sensitivity studies. A review.

    abstract：:Traditionally cervical dentinal sensitivity (CDS) has been evaluated mainly subjectively on the basis of the individual patient's subjective response, e.g., in the form of verbal rating and visual analogue scales and questionnaires. The stimuli used for evaluating this response can be grouped into 4 main categories: m...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,评审

    doi：10.1111/j.1600-051x.1993.tb00378.x

    authors： Gillam DG,Newman HN

    更新日期：1993-07-01 00:00:00