Abstract:
PURPOSE:The risk of an injury increases exponentially with alcohol consumption on a given occasion, but the conclusion that alcohol-related injuries are attributable primarily to heavy drinking may or may not be correct. The prevention paradox states that a large number of people at small risk may contribute more cases of a particular condition than a smaller number of people who are individually at greater risk. We sought to determine the extent to which the prevention paradox applies in the relationship between alcohol consumption and injury. METHODS:We conducted a population-based case-control and case-crossover study in all 3 emergency departments in Boone County, Mo. Data were collected from 2,517 patients with an acute injury and 1,856 age- and sex-matched controls selected by random digit dialing. RESULTS:The population attributable fraction (PAF) associated with drinking in the 6 hours before injury-the proportion of injuries that would not have occurred in the absence of drinking-was 10.6% in case-crossover analysis and 8.5% in case-control analysis. The PAF that was due to what is usually considered nonhazardous alcohol consumption (fewer than 5 drinks for men, fewer than 4 for women) was 4.5% in case-crossover analysis and 3.1% in case-control analysis. The PAF that was due to alcohol dependence was 4.0%. CONCLUSIONS:Injury is associated more with an occasion of alcohol consumption than with alcohol dependence. A substantial proportion of the PAF that is due to an occasion of alcohol consumption is from what are usually considered low-risk quantities.
journal_name
Ann Fam Medjournal_title
Annals of family medicineauthors
Spurling MC,Vinson DCdoi
10.1370/afm.243keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
47-52issue
1eissn
1544-1709issn
1544-1717pii
3/1/47journal_volume
3pub_type
杂志文章abstract:PURPOSE:Avoidable hospitalizations due to adverse drug events and high-risk prescribing are common in older people. Primary care physicians prescribe most on-going medicines. Deprescribing has long been essential to best prescribing practice. We sought to explore the views of primary care physicians on the barriers and...
journal_title:Annals of family medicine
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更新日期:2004-01-01 00:00:00
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abstract::William Osler is quoted as saying, "Nothing will sustain you more potently than the power to recognize in your humdrum routine, as perhaps it may be thought, the true poetry of life-the poetry of the commonplace, of the plain, toil-worn woman, with their loves and their joys, their sorrows and their griefs."(1) A fami...
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更新日期:2014-05-01 00:00:00
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更新日期:2016-05-01 00:00:00
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更新日期:2004-09-01 00:00:00
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更新日期:2016-09-01 00:00:00