Abstract:
PURPOSE:Multimorbidity is associated with adverse outcomes, yet research on the determinants of its incidence is lacking. We investigated which sociodemographic, health, and individual lifestyle (eg, physical activity, smoking behavior, body mass index) characteristics predict new cases of multimorbidity. METHODS:We used data from 4,564 participants aged 50 years and older in the English Longitudinal Study of Aging that included a 10-year follow-up period. Discrete time-to-event (complementary log-log) models were constructed for exploring the associations of baseline characteristics with outcomes between 2002-2003 and 2012-2013 separately for participants with no initial conditions (n = 1,377) developing multimorbidity, any increase in conditions within 10 years regardless of initial conditions, and the impact of individual conditions on incident multimorbidity. RESULTS:The risks of developing multimorbidity were positively associated with age, and they were greater for the least wealthy, for participants who were obese, and for those who reported the lowest levels of physical activity or an external locus of control (believing that life events are outside of one's control) for all groups regardless of baseline conditions (all linear trends <.05). No significant associations were observed for sex, educational attainment, or social detachment. For participants with any increase in conditions (n = 4,564), a history of smoking was the only additional predictor. For participants with a single baseline condition (n = 1,534), chronic obstructive pulmonary disease (COPD), asthma, and arrhythmia showed the strongest associations with subsequent multimorbidity. CONCLUSIONS:Our findings support the development and implementation of a strategy targeting the prevention of multimorbidity for susceptible groups. This approach should incorporate behavior change addressing lifestyle factors and target health-related locus of control.
journal_name
Ann Fam Medjournal_title
Annals of family medicineauthors
Mounce LTA,Campbell JL,Henley WE,Tejerina Arreal MC,Porter I,Valderas JMdoi
10.1370/afm.2271subject
Has Abstractpub_date
2018-07-01 00:00:00pages
322-329issue
4eissn
1544-1709issn
1544-1717pii
16/4/322journal_volume
16pub_type
杂志文章abstract:PURPOSE:Adolescent mothers are at risk for rapidly becoming pregnant again and for depression, school dropout, and poor parenting. We evaluated the impact of a community-based home-visiting program on these outcomes and on linking the adolescents with primary care. METHODS:Pregnant adolescents aged 12 to 18 years, pre...
journal_title:Annals of family medicine
pub_type: 杂志文章,随机对照试验
doi:10.1370/afm.629
更新日期:2007-05-01 00:00:00
abstract::As a result of a large and compelling body of evidence documenting the impacts of social determinants, such as income and education, on health outcomes, health care systems are beginning to incorporate social and economic risk data into health care delivery decisions. But there is a risk that some of these efforts cou...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2339
更新日期:2019-01-01 00:00:00
abstract::Behavioral change is at the heart of effective primary care, but when patients don't change, how do we account for our days? In this personal essay, I relate an encounter with a patient who wants to quit smoking, lose weight, and control her diabetes. I am discouraged when she deflects my recommendations, but a collea...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1781
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:We undertook a study to understand how women who are victims of intimate partner violence (IPV) want physicians to manage these abusive relationships in the primary care office. METHODS:Thirty-two mothers in IPV shelters or support groups in southwestern Ohio were interviewed to explore their abuse experien...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.74
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:In this study, we compared the rate of depression diagnoses in adults with and without diabetes mellitus, while carefully controlling for number of primary care visits. METHODS:We matched adults with incident diabetes (n = 2,932) or prevalent diabetes (n = 14,144) to nondiabetic control patients based on (1) a...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.964
更新日期:2009-07-01 00:00:00
abstract:PURPOSE:The health care system in the United States is inherently hierarchical. Patients are "nested" within physicians who in turn are "nested" within practices. Much of the research data gathered in practice-based research networks (PBRNs) also have similar patterns of nesting (clustering). When research data are nes...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.340
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:Overtreatment of screen-detected localized prostate cancer (LPC) is an important public health concern, since the survival benefit of aggressive treatment (surgery or radiation) has not been well established. We investigated the survival expectations of patients who had LPC with and without their chosen treatme...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1926
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Qualitative research projects often involve the collaborative efforts of a research team. Challenges inherent in teamwork include changes in membership and differences in analytical style, philosophy, training, experience, and skill. This article discusses teamwork issues and tools and techniques used to improv...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.290
更新日期:2005-07-01 00:00:00
abstract::Large panel sizes are often held responsible for worse access to appointments in primary care. We evaluated the relationship between appointment backlog, panel size, and primary care clinician time in clinic, using Spearman correlation and multiple regression in a retrospective analysis. We found no independent associ...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2313
更新日期:2018-11-01 00:00:00
abstract::During a night of severe pain and weakness, I found several plausible-sounding diagnoses online: occipital neuralgia, nerve damage, and meningitis. The next day, I consulted a physician who did not offer professional guidance; instead the physician suggested tests entirely based on my self-diagnoses. What resulted was...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2414
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The 5As (ask, advise, assess, assist, arrange) are recommended as a strategy for brief physical activity counseling in primary care. There is no reference standard for measurement, however, and patient participation is not well understood. This study's objectives were to (1) develop a coding scheme to measur...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1299
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:The risk of an injury increases exponentially with alcohol consumption on a given occasion, but the conclusion that alcohol-related injuries are attributable primarily to heavy drinking may or may not be correct. The prevention paradox states that a large number of people at small risk may contribute more cases...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.243
更新日期:2005-01-01 00:00:00
abstract::Cultural values and beliefs about the primary care physician bolster the myth of the lone physician: a competent professional who is esteemed by colleagues and patients for his or her willingness to sacrifice self, accept complete responsibility for care, maintain continuity and accessibility, and assume the role of l...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1353
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Practice transformation is the cornerstone of the future of family medicine and health care reform, but little is known about how the process occurs. We sought to develop and test a model of the natural history of practice transformation. METHODS:We developed an outcomes-based model of how a practice moves thr...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1497
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:Up to 50% of urinary tract infections (UTIs) in young children are missed in primary care. Urine culture is essential for diagnosis, but urine collection is often difficult. Our aim was to derive and internally validate a 2-step clinical rule using (1) symptoms and signs to select children for urine collection;...
journal_title:Annals of family medicine
pub_type: 杂志文章,多中心研究
doi:10.1370/afm.1954
更新日期:2016-07-01 00:00:00
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journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1949
更新日期:2016-09-01 00:00:00
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journal_title:Annals of family medicine
pub_type: 杂志文章,多中心研究
doi:10.1370/afm.2179
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:This review summarizes the evidence regarding the efficacy of adjuvant steroids for pain reduction in acute pharyngitis. METHODS:We searched for randomized controlled trials, using MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews, published between 1966 and December 2008. Two reviewers assessed...
journal_title:Annals of family medicine
pub_type: 杂志文章,评审
doi:10.1370/afm.1038
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:We wanted to understand the views of patients and clinicians on the central concept of healing and to identify major facilitators of and barriers to promoting healing in primary care. METHODS:We undertook a qualitative analysis of focus group discussions. Participants were drawn from primary care clinics of a ...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.838
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:The explosion of evidence in the last decade supporting the role of spirituality in whole-person patient care has prompted proposals for a move to a biopsychosocial-spiritual model for health. Making this paradigm shift in today's multicultural societies poses many challenges, however. This article presents 2 t...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.864
更新日期:2008-09-01 00:00:00
abstract::Tobacco use, lack of physical activity and poor diet, and alcohol consumption are leading causes of death in the United States. We estimated screening and counseling rates by using a nationally representative sample of adults aged 35 years and older with a preventive care supplement to the 2014 Medical Expenditure Pan...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2363
更新日期:2019-03-01 00:00:00
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journal_title:Annals of family medicine
pub_type: 杂志文章
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更新日期:2004-11-01 00:00:00
abstract:PURPOSE:The US Preventive Services Task Force (USPSTF) is authorized by the US government to review and disseminate the scientific evidence for clinical preventive services. The purpose of this study was to evaluate the alignment of Medicare preventive services coverage with the recommendations of the USPSTF before imp...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1194
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To address doubts regarding National Lung Screening Trial (NLST) generalizability, we analyzed over 6,000 lung cancer screenings (LCSs) within a community health system. METHODS:Our LCS program included 10 sites, 7 hospitals (2 non-university tertiary care, 5 community) and 3 free-standing imaging centers. Pri...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2519
更新日期:2020-05-01 00:00:00
abstract::Hatpins is a first-person narrative that delves into a physician's experience of a patient death during the early years of residency. The essay reflects on the conflicted physician-patient relationships that can develop even over the short tenure of residency. While residency seeks to create medically prepared and com...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.2135
更新日期:2017-11-01 00:00:00
abstract::Two voices tell the story of an evolving doctor-patient relationship. Seizures are the first indication of squamous cell lung cancer metastatic to the brain. Both doctor and patient describe the course of the illness, treatment, and remarkable recovery, each from his own perspective. The patient describes how the canc...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.9
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:We wanted to identify differences between diabetic patients who smoke and those who do not smoke to design more effective strategies to improve their diabetes care and encourage smoking cessation. METHODS:A random sample of adult health plan members with diabetes were mailed a survey questionnaire, with tel...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.36
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the association between the prevalence of both diabetes-concordant and diabetes-discordant conditions and the quality of diabetes care at the family practice level in England. We hypothesized that the prevalence of concordant (or discordant) conditions would be associate...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.1848
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:A randomized controlled trial found that patients with diabetes had lower HbA1c levels after 6 months of peer health coaching than patients who did not receive coaching. This paper explores whether the peer coaches in that trial, all low-income patients with diabetes, mastered and utilized an evidence-based hea...
journal_title:Annals of family medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Most new mothers return to work soon after childbirth. A need exists to reexamine the definition of postpartum health and evaluate employed women's recovery from childbirth in association with such factors as delivery type and breastfeeding. METHODS:Using a prospective cohort design, we recruited Minnesota wom...
journal_title:Annals of family medicine
pub_type: 杂志文章
doi:10.1370/afm.519
更新日期:2006-03-01 00:00:00