Abstract:
AIMS:To measure plasma concentrations of endothelin (ET)-1, NO metabolites (nitrate/nitrite; NOx) and 6-keto PGF1 alpha (PGF1 alpha) in maternal and fetal sheep blood, and to evaluate the effects of big ET-1 on hemodynamic response, blood gases and NO and 6-keto PGF1 alpha production in near term fetal sheep. METHODS:Hemodynamic parameters were measured during infusion of big ET-1 into the carotid vein in chronically catheterized fetal sheep on day 125 of gestation. Fetal arterial blood samples were obtained for ET-1, PGF1 alpha) and nitrate/nitrite (NOx) measurements. RESULTS:ET-1, NOx and PGF1 alpha plasma concentrations were all significantly higher in fetal compared with the maternal plasma. Big ET-1 significantly decreased fetal systolic and diastolic blood pressure and significantly increased fetal heart rate. Big ET-1 stimulated plasma PGF1 alpha), but not NOx , concentration. CONCLUSIONS:Circulatory regulating factors in the fetus were up-regulated. The effects of ET-1 on fetal hemodynamic response may be mediated via prostacyclin, but not via the NO pathway.
journal_name
J Perinat Medjournal_title
Journal of perinatal medicineauthors
Okawa T,Honda S,Sanpei M,Ishida T,Fujimori K,Sato Adoi
10.1515/JPM.2004.149keywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
495-9issue
6eissn
0300-5577issn
1619-3997journal_volume
32pub_type
杂志文章abstract:OBJECTIVE:This prospective observational study evaluated maternal symptoms and characteristics that predict successful labor induction with oral misoprostol. METHODS:A total of 244 consecutive women undergoing labor induction voluntarily completed a questionnaire about subjective sensations and pain scores during the ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm.2011.032
更新日期:2011-05-01 00:00:00
abstract::Background Monocytes, after neutrophils, are the most abundant white blood cells found in the amniotic cavity of women with intra-amniotic inflammation/infection. However, the origin of such cells has not been fully investigated. Herein, we determined (1) the origin of amniotic fluid monocytes/macrophages from women w...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2019-0262
更新日期:2019-10-25 00:00:00
abstract:OBJECTIVE:To compare the outcome of induction of labor and patient's preferences using a protocol with the first dose of prostaglandin E2 endocervical gel in the evening versus a protocol with the first dose in the morning. DESIGN:We performed a randomized trial comparing administration of prostaglandin E2 endocervica...
journal_title:Journal of perinatal medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1515/JPM.2000.003
更新日期:2000-01-01 00:00:00
abstract:AIM:The aim of this study was to review prenatally diagnosed tumors of the head and neck in the fetus and to report antenatal and postnatal outcomes. METHODS:PubMed/Medline, EMBASE/SCOPUS, Cochrane database and Google Scholar were reviewed over the last 20 years. No language or article type restriction was used. RESU...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2016-0074
更新日期:2017-02-01 00:00:00
abstract::The renin-angiotensin system and dietary sodium have been repeatedly implicated in the pathogenesis of pregnancy induced hypertension (PIH). Mechanisms responsible for increased vascular responsiveness to angiotensin II (A-II) observed in PIH are not completely understood. Plasma A-II levels and blood pressure are fun...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1984.12.4.167
更新日期:1984-01-01 00:00:00
abstract:OBJECTIVE:To assess risk factors for adverse perinatal and neonatal outcomes in "well-selected" singleton vaginal breech deliveries at term. METHODS:During the time span from January 2008 up to April 2015 a total of 786 singleton term breech deliveries with a planned vaginal delivery were identified in a retrospective...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0342
更新日期:2017-04-01 00:00:00
abstract::We assayed inorganic sulfate by ion chromatography in 49 amniotic fluid samples from pregnancies of 14 to 38 weeks gestation. In second trimester samples (14 to 26 weeks gestation), amniotic fluid sulfate concentrations (317 +/- 22 mumol/L, mean +/- SE; n = 32) were not different from previously reported maternal seru...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1992.20.6.443
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To determine pregnancy outcome in patients with short cervix on transvaginal ultrasound between 16 and 24 weeks' gestation treated with McDonald cerclage compared to weekly intramuscular injections of 17 alpha-hydroxyprogesterone caproate (17OHP-C). METHODS:From November 2003 through December 2006, asymptoma...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,随机对照试验
doi:10.1515/JPM.2009.083
更新日期:2009-01-01 00:00:00
abstract::In order to evaluate the determinants of high and low ponderal indices in triplets, we analyzed prospectively collected data from a cohort of 2181 triplet births. Low and high neonatal ponderal indices (birth weight/[length]3) were defined as below or above 1 SD from the mean. The mean ponderal index was of 2.4 +/- 0....
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2004.012
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The Apgar score is used worldwide to assess the newborn infant shortly after birth. Apgar scores, including mean scores and those with high cut-off scores, have been used to support claims that planned home birth is as safe as hospital birth. The purpose of this study was to determine the distribution of 5 m...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2014-0003
更新日期:2015-07-01 00:00:00
abstract::Histologic examination of the skeletal muscles in 8 fetuses and newborn patients with the Pena-Shokeir sequence revealed only minor nonspecific changes which could not be ascribed to any of the well defined myopathies. Muscle fiber diameters were increased in 2 out of 5 patients examined. No significant malformations ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1990.18.4.267
更新日期:1990-01-01 00:00:00
abstract::An infant is reported who was identified antenatally to have an extralobar sequestration and a pleural effusion. Chronic drainage of the effusion was achieved by placement of a pleuroamniotic shunt. After delivery the infant underwent several thoracocenteses and then definitive surgery to remove an extralobar sequestr...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1996.24.4.335
更新日期:1996-01-01 00:00:00
abstract::The occurrence, predictive factors and associated morbidity of bronchopulmonary dysplasia (BPD) was examined in a preterm birth cohort of 712 children, born before 37 weeks of gestation to residents of a geographically defined area between 1978-82. All cases of BPD (N = 16) were born at or before 32 weeks of gestation...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1988.16.5-6.437
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Placement of a cervical cerclage at mid-trimester in women at risk for preterm labor is a common procedure with apparent benefits for some women. However, the changes that occur in the cervix following this procedure remain incompletely identified. METHODS:We evaluated the endocervical concentrations of medi...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2011.132
更新日期:2011-11-25 00:00:00
abstract::Assessment of fetal movements by the pregnant woman is a useful screening test in high and low risk pregnancies. Decreased fetal movements to less than 10 during 12 hours is an expression of fetal distress, and may be the first alert of impending fetal death. Pregnancies with decreased fetal activity comprise a very h...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1983.11.3.175
更新日期:1983-01-01 00:00:00
abstract::The absence of one umbilical artery of single umbilical artery (SUA) is one of the most common congenital malformations in man. This vascular anomaly of the umbilical cord is frequently associated with other congenital malformations as well as some adverse perinatal events such as intrauterine growth retardation (IUGR...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1991.19.5.391
更新日期:1991-01-01 00:00:00
abstract:OBJECT:To assess whether transvaginal ultrasound is helpful in predicting the post-term onset of labor (> or = 1 weeks). SETTING:Antenatal clinic of a University hospital and referral center. SUBJECT AND MEHODS: One hundred and twenty singleton uncomplicated pregnancies in primiparous women were enrolled at 37 weeks o...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2001.045
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To examine the proportion of iatrogenic births among all preterm births over a 26-year period. PATIENTS AND METHODS:A registry-based survey of preterm deliveries between 1987 and 2012 analyzed by the onset of labor: spontaneous with intact membranes, preterm premature rupture of membranes (PPROM) or iatrogen...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2015-0271
更新日期:2016-07-01 00:00:00
abstract::This paper reports two cases of abruptio placentae assessed using pulsed Doppler at 29 and 30 weeks of gestation. Transvaginal pulsed Doppler showed abnormal uterine artery FVWs in both cases. One fetus with normal umbilical and normal middle cerebral artery FVWs was not acidotic and only midly hypoxic, whereas the ot...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1994.22.5.441
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To evaluate differences in placental lesions in twin pregnancies with and without mid-trimester sonographic cervical shortening.
METHODS:Two groups of women were identified: those with twin gestations and a cervical length journal_title:Journal of perinatal medicine pub_type: 杂志文章 doi:10.1515/jpm.2010.077 更新日期:2010-09-01 00:00:00
abstract:AIM:To assess the sonographic cervical characteristics between nulliparous and multiparous women. SUBJECT AND METHODS:Transvaginal three-dimensional ultrasound and power Doppler using the virtual organ computer-aided analysis (VOCAL) program were performed on 71 nulliparas and 59 multiparas at a mean gestational age o...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2007.007
更新日期:2007-01-01 00:00:00
abstract::Objective To determine the association between pre-gravid obesity and stillbirth. Methods A retrospective study of a population-based dataset of births at ≥34 weeks' gestation. We excluded fetal deaths due to lethal anomalies and intrapartum fetal deaths. We calculated the incidence of stillbirths, neonatal respirator...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2018-0266
更新日期:2019-04-24 00:00:00
abstract::Dilatation of the fetal cerebral ventricles (ventriculomegaly) is a generic sonographic sign common to several pathological entities carrying different prognoses. The main causes of fetal ventriculomegaly are aqueductal stenosis, Chiari II malformation, Dandy-Walker complex and agenesis of the corpus callosum. Ventric...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/JPM.2004.002
更新日期:2004-01-01 00:00:00
abstract:AIMS:Psychosocial stress during pregnancy (PSP) is a risk factor of growing interest in the etiology of preterm birth (PTB). This literature review assesses the published evidence concerning the association between PSP and PTB, highlighting established and hypothesized physiological pathways mediating this association....
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2012-0295
更新日期:2013-11-01 00:00:00
abstract::A survey of the clinical records of fifteen fetuses with trisomy 21, six fetuses with trisomy 18, and two fetuses with trisomy 13 was made in order to find out typical patterns of fetal heart rate (FHR) possibly associated with these conditions. Antepartal FHR patterns of 55 normal pregnancies and intrapartal FHR patt...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1982.10.5.242
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To analyze data from a registry of Japanese neonates with hypoxic respiratory failure associated with pulmonary hypertension (PH) to compare the effectiveness of inhaled nitric oxide (iNO) in neonates born <34 weeks vs. ≥34 weeks gestational age (GA). MATERIALS AND METHODS:iNO was administered according to a...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpm-2017-0040
更新日期:2018-08-28 00:00:00
abstract:OBJECTIVE:To determine whether first-trimester measurements of maternal serum PAPP-A and free beta hCG levels were associated with adverse pregnancy outcomes. STUDY DESIGN:First trimester maternal serum free beta hCG and PAPP-A were measured in 490 singleton pregnancies. Pregnancies were followed by the fetal-maternal...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2006.026
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To examine the obstetrical risk factors for death and brain injury among extremely-low-birth-weight (ELBW) infants (birth weight <1000 g). STUDY DESIGN:Study subjects were 121 ELBW infants born at a single tertiary perinatal center. Death among ELBW infants was considered to have occurred when subjects died ...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/JPM.2007.111
更新日期:2007-01-01 00:00:00
abstract::The outbreak of the SARS-CoV-2 elicited a surge in publications. Obstetric reports were with few exceptions characterized by small sample sizes with potentially limited generalizability. In this review, evidence suggests increased susceptibility to COVID-19 in pregnancy; common pregnancy comorbidities may help explain...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章,评审
doi:10.1515/jpm-2020-0399
更新日期:2020-11-26 00:00:00
abstract::On 11 near term pregnant sheep the response of the fetal transcutaneous oxygen partial pressure (tcPO2) was compared with the alteration of the oxygen saturation (SO2) and the PO2 in the fetal aorta (FA), fetal heart rate (FHR) and fetal arterial blood pressure (FA BP) following the reduction of uterine blood flow (UB...
journal_title:Journal of perinatal medicine
pub_type: 杂志文章
doi:10.1515/jpme.1980.8.2.85
更新日期:1980-01-01 00:00:00