Itraconazole (Sporanox) in superficial and systemic fungal infections.

abstract：INTRODUCTION:Latent tuberculosis infection (LTBI) accounts for almost a quarter of the world population, and, in 5-10% of the subjects with impaired immune-response against M. tuberculosis growth, it may progress to active tuberculosis (TB). In this review, we focus on the need to propose a screening for LTBI including...

journal_title：Expert review of anti-infective therapy

authors： Goletti D,Petrone L,Ippolito G,Niccoli L,Nannini C,Cantini F

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Drug-resistant tuberculous meningitis has been reported worldwide. Isoniazid mono-resistance is the most frequent cause of drug-resistant tuberculous meningitis, a life-threatening disease. Extensive drug-resistant tuberculous meningitis has also been reported in some isolated case reports. Areas covered: ...

journal_title：Expert review of anti-infective therapy

authors： Garg RK,Rizvi I,Malhotra HS,Uniyal R,Kumar N

更新日期：2018-11-01 00:00:00

abstract：:Introduction: Among the multidrug resistant pathogens, extended-spectrum beta-lactamase (ESBL-E) or carbapenemase-producing Enterobacteriaceae (CPE) are currently considered the main threat due to the scarcity of therapeutic options and their rapid spread around the globe. In addition to developing new antibiotics and...

journal_title：Expert review of anti-infective therapy

authors： Catho G,Huttner BD

更新日期：2019-08-01 00:00:00

abstract：:Evaluation of: Riedel S, Melendez JH, An AT, Rosenbaum JE, Zenilman JM. Procalcitonin as a marker for the detection of bacteremia and sepsis in the emergency department. Am. J. Clin. Pathol. 135(2), 182-189 (2011). In a recent report, Riedel et al. proposed a procalcitonin cutoff of 0.1 ng/ml to rule out bacteremia in...

journal_title：Expert review of anti-infective therapy

authors： Albrich WC,Mueller B

更新日期：2011-06-01 00:00:00

abstract：:Drug resistance in HIV-infected children is one of the main contributors to antiretroviral treatment (ART) failure, especially in developing countries. Sub-Saharan Africa has the largest burden of pediatric HIV infection in the world. Herein, we systematically review the current status of ART failure in HIV-infected A...

journal_title：Expert review of anti-infective therapy

authors： Jenabian MA,Costiniuk CT,Mboumba Bouassa RS,Chapdeleine Mekue Mouafo L,Brogan TV,Bélec L

更新日期：2015-01-01 00:00:00

abstract：:Meningococcal disease is a life-threatening condition and a major cause of bacterial meningitis and sepsis worldwide. In many fatal cases, meningococcal disease is rapidly progressive and death occurs within hours of the initial symptoms. The early identification of patients at high risk of death would be useful in or...

journal_title：Expert review of anti-infective therapy

authors： Montero-Martín M,Inwald DP,Carrol ED,Martinón-Torres F

更新日期：2014-11-01 00:00:00

abstract：:The acyclic nucleoside phosphonates [HPMPC: cidofovir, Vistide; PMEA: adefovir dipivoxil, Hepsera; and PMPA: tenofovir, Viread] have proven to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections, for example, cidofo...

journal_title：Expert review of anti-infective therapy

authors： De Clercq E

更新日期：2003-06-01 00:00:00

abstract：:GB virus C (GBV-C) is a member of the Flaviviridae family and the most closely related human virus to HCV. However, GBV-C does not replicate in hepatocytes, but rather in lymphocytes. GBV-C has a worldwide distribution and is transmitted sexually, parenterally and through mother-to-child transmission. Thus, co-infecti...

journal_title：Expert review of anti-infective therapy

authors： Schwarze-Zander C,Blackard JT,Rockstroh JK

更新日期：2012-05-01 00:00:00

abstract：:Inhaled antibiotics are not usually considered outside the setting of cystic fibrosis or Pneumocystis jiroveci prophylaxis. However, because they deliver high drug concentrations at the site of infection with negligible systemic absorption and toxicity, they are logical compliments to standard intravenous therapy for ...

journal_title：Expert review of anti-infective therapy

authors： Lesho E

更新日期：2005-06-01 00:00:00

abstract：:Neurocysticercosis is a major cause of neurologic disease worldwide. In India and other developing countries, single small enhancing computed tomographic lesions representing solitary cysticercus granuloma are a common cause of new-onset seizures. The interesting feature of these solitary enhancing lesions is their sp...

journal_title：Expert review of anti-infective therapy

authors： Garg RK

更新日期：2008-02-01 00:00:00

abstract：INTRODUCTION:Onychomycosis is a chronic fungal infection of the nail bed, matrix or plate. It accounts for roughly 50% of all nail disease. As the prevalence of onychomycosis is increasing, a critical review of diagnostic techniques and treatment options is required. Areas covered: This review discusses the current dia...

journal_title：Expert review of anti-infective therapy

authors： Gupta AK,Mays RR,Versteeg SG,Shear NH,Piguet V

更新日期：2018-12-01 00:00:00

abstract：:Pre- and neonatal screening for congenital toxoplasmosis rests upon the assumption that treatment is beneficial on either acute symptoms or in preventing later reactivation. Postpartum treatment of congenital toxoplasmosis with sulfadiazine and pyrimethamine has remained almost unchanged for 50 years. More recently, s...

journal_title：Expert review of anti-infective therapy

authors： Petersen E,Schmidt DR

更新日期：2003-06-01 00:00:00

abstract：:A current focus in HIV management is improving adherence by minimizing pill burden with convenient formulations, including fixed-dose combinations (FDCs). Darunavir, a HIV protease inhibitor, co-administered with low-dose ritonavir (800/100 mg once daily), is recommended in guidelines in combination with other antiret...

journal_title：Expert review of anti-infective therapy

authors： Kakuda TN,Crauwels H,Opsomer M,Tomaka F,van de Casteele T,Vanveggel S,Iterbeke K,de Smedt G

更新日期：2015-06-01 00:00:00

abstract：:Inflammation represents a complex biologic and biochemical process involving cells of the immune system and a plethora of biologic mediators in response to mechanical, chemical or infectious injuries. When mobilization of effector cells and molecules becomes excessive, the beneficial aspect of this response--to limit ...

journal_title：Expert review of anti-infective therapy

authors： Labro MT

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Microorganisms of clinical importance frequently develop resistance to drug therapy, now a growing problem. The experience with Mycobacterium tuberculosis is a representative example of increasing multi-drug resistance. To avoid reaching a crisis in which patients could be left without adequate treatment, ...

journal_title：Expert review of anti-infective therapy

authors： Guevara Salazar JA,Morán Díaz JR,Ramírez Segura E,Trujillo Ferrara JG

更新日期：2020-10-26 00:00:00

abstract：:Hospital infection due to multidrug-resistant Gram-positive bacteria may often represent a life-threatening challenge; thus, to appropriately combat them, clinicians should be confident and systematically apply several important pharmacodynamic concepts. The concept of 'correct antibiotic treatment' should include, in...

journal_title：Expert review of anti-infective therapy

authors： Pea F,Viale P

更新日期：2007-04-01 00:00:00

abstract：:As a consequence of antibiotic overuse and misuse, nosocomial infections caused by multidrug-resistant bacteria represent a physician's nightmare throughout the world. No newer antimicrobials active against Pseudomonas aeruginosa, the main multidrug-resistant nosocomial pathogen, are available or under investigation. ...

journal_title：Expert review of anti-infective therapy

authors： Giamarellou H

更新日期：2006-08-01 00:00:00

abstract：:Escherichia coli has become multiresistant by way of production of a variety of β-lactamases. The prevalence of CTX-M-producing E. coli has reached 60-79% in certain parts of Asia. The acquisition of CTX-M plasmids by E. coli sequence type 131, a successful clone of E. coli, has caused further dissemination of CTX-M-p...

journal_title：Expert review of anti-infective therapy

authors： Sidjabat HE,Paterson DL

更新日期：2015-05-01 00:00:00

abstract：:In recent decades, the incidence of aspergillosis, candidiasis and clinically important deep mycoses has been increasing, with advances in transplantation medicine and anticancer chemotherapy. Micafungin (FK463, Fujisawa Healthcare) has been developed as a novel type of antifungal agent, which inhibits 1,3-beta-D-gluc...

journal_title：Expert review of anti-infective therapy

authors： Higashiyama Y,Kohno S

更新日期：2004-06-01 00:00:00

abstract：:Antibiotic resistance is an important factor influencing clinical outcome for patients in intensive care units. It is also associated with increased healthcare costs resulting from prolonged patient stays. The problem of antibiotic resistance is particularly acute in intensive care units because they house seriously i...

journal_title：Expert review of anti-infective therapy

authors： Johnson AP

更新日期：2003-08-01 00:00:00

abstract：:Objectives: Extent of post-treatment fibrosis change in patients with different stages of fibrosis not fully known. We aimed to study changes in liver fibrosis in chronic hepatitis C patients who were treated with pegylated interferon/ribavirin (PEG/RBV) or direct acting antivirals (DAAs). Methods: Retrospective evalu...

journal_title：Expert review of anti-infective therapy

authors： Abdelsameea E,Alsebaey A,Abdel-Samiee M,Abdel-Razek W,Salama M,Waked I

更新日期：2020-12-29 00:00:00

abstract：:Chronic rhinosinusitis (CRS) is a common health care problem, yet many aspects of this diagnosis remain poorly understood. Its etiology is often debated and remains a significant area of research. The diagnosis of CRS is based on subjective symptoms, duration of symptoms and objective evidence of inflammation. Each of...

journal_title：Expert review of anti-infective therapy

authors： Manes RP,Batra PS

更新日期：2013-01-01 00:00:00

abstract：:Ebola and Marburg viruses are emerging/re-emerging pathogens that pose a significant threat to human health. These naturally occurring viral infections frequently cause a lethal hemorrhagic fever in humans and nonhuman primates. The disastrous consequences of infection with these viruses have been pursued as potential...

journal_title：Expert review of anti-infective therapy

authors： Paragas J,Geisbert TW

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Tocilizumab, an inhibitor of the interleukin-6 receptor, may decrease the inflammatory response and control the symptoms of severe coronavirus disease 2019 (COVID-19), but the evidence is scarce. METHODS:This retrospective study included patients with severe COVID-19 requiring oxygen therapy who received to...

journal_title：Expert review of anti-infective therapy

authors： Tomasiewicz K,Piekarska A,Stempkowska-Rejek J,Serafińska S,Gawkowska A,Parczewski M,Niścigorska-Olsen J,Łapiński TW,Zarębska-Michaluk D,Kowalska JD,Horban A,Flisiak R

更新日期：2021-01-01 00:00:00

abstract：:Diarrhoea is one of the most commonly occurring diseases. This article presents a review of the current state of the treatment of acute infectious diarrhoea, as well as of the most important pathogens. The general principles of the therapy of diarrhoea are exemplified, followed by a description of the targeted antimic...

journal_title：Expert review of anti-infective therapy

authors： Lübbert C

更新日期：2016-01-01 00:00:00

abstract：:Lymphatic filariasis (LF) is an important public health problem endemic in 73 countries, where it is a major cause of acute and chronic morbidity and a significant impediment to socioeconomic development. It is targeted for elimination by 2020, through preventive chemotherapy using albendazole in combination with eith...

journal_title：Expert review of anti-infective therapy

authors： Rebollo MP,Bockarie MJ

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:The pathogenic and highly transmissible etiological agent, SARS-CoV-2, has caused a serious threat COVID-19 pandemic. WHO has declared the epidemic a public health emergency of international concern owing to its high contagiosity, mortality rate, and morbidity. Till now, there is no approved vaccine or dru...

journal_title：Expert review of anti-infective therapy

authors： Hossain MJ,Rahman SMA

更新日期：2020-12-23 00:00:00

abstract：:HIV-associated nephropathy (HIVAN) is the most well-known and aggressive kidney disease in HIV-1-infected patients. A variant of focal segmental glomerulosclerosis, it is characterized by the collapse of the glomerular tuft with podocyte hypertrophy/hyperplasia and foot process effacement, often with concurrent tubula...

journal_title：Expert review of anti-infective therapy

authors： Atta MG,Lucas GM,Fine DM

更新日期：2008-06-01 00:00:00

abstract：:Management of anaerobic infections encompasses surgical procedures, antibacterial therapy and adjuncts. At present, metronidazole, penems, beta-lactam/beta-lactamase inhibitor combinations and chloramphenicol have the highest activity against obligate anaerobes. Tigecycline is a promising new agent. Other antibacteria...

journal_title：Expert review of anti-infective therapy

authors： Boyanova L,Kolarov R,Mitov I

更新日期：2007-08-01 00:00:00

abstract：:Fluoroquinolones are an important group of antibiotics that are used widely in the treatment of various infectious diseases in adults as a result of their excellent spectrum of activity, significant tissue penetration and convenient routes of administration. Their use in children, however, has been limited until recen...

journal_title：Expert review of anti-infective therapy

authors： Velissariou IM

更新日期：2006-10-01 00:00:00