Abstract:
BACKGROUND:Effective hemostatic treatment is mandatory for patients with actively bleeding Mallory-Weiss syndrome. This study evaluated the respective efficacy and the safety of endoscopic band ligation and endoscopic epinephrine injection in Mallory-Weiss syndrome. METHODS:Thirty-four consecutive patients with actively bleeding Mallory-Weiss syndrome were prospectively enrolled and were randomly assigned to undergo endoscopic band ligation or endoscopic injections of a 1:10,000 solution of epinephrine. Demographic characteristics, endoscopic variables, and outcome parameters, including rates of hemostasis and recurrent bleeding, were analyzed. RESULTS:The number of elastic bands applied was one or two; the mean volume of epinephrine injected was 18.0 mL: 95% CI[16.8, 19.2]. There was no significant difference between the groups with respect to age, gender, alcohol ingestion, presenting symptoms, Hb level, shock, comorbid diseases, coagulopathy, tear location, blood transfusion, or duration of hospitalization. Primary hemostasis was achieved in all 17 patients in the band ligation group and in 16 of 17 patients (94.1%) in the epinephrine injection group. There was no recurrence of bleeding or major complication in either group. CONCLUSIONS:In this small study, no difference was detected in the efficacy or the safety of band ligation vs. epinephrine injection for the treatment of actively bleeding Mallory-Weiss syndrome.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Park CH,Min SW,Sohn YH,Lee WS,Joo YE,Kim HS,Choi SK,Rew JS,Kim SJdoi
10.1016/s0016-5107(04)01284-2keywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
22-7issue
1eissn
0016-5107issn
1097-6779pii
S0016-5107(04)01284-2journal_volume
60pub_type
临床试验,杂志文章,随机对照试验abstract::Electronic chromoendoscopy technologies provide image enhancement and may improve the diagnosis of mucosal lesions. Although strides have been made in standardization of image characterization, especially with NBI, further image-to-pathology correlation and validation are required. There is promise for the development...
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journal_title:Gastrointestinal endoscopy
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pub_type: 临床试验,杂志文章,随机对照试验
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