Transformation of folate-consuming Lactobacillus gasseri into a folate producer.

Abstract:

:Five genes essential for folate biosynthesis in Lactococcus lactis were cloned on a broad-host-range lactococcal vector and were transferred to the folate auxotroph Lactobacillus gasseri. As a result L. gasseri changed from a folate consumer to a folate producer. This principle can be used to increase folate levels in many fermented food products.

journal_name

Appl Environ Microbiol

authors

Wegkamp A,Starrenburg M,de Vos WM,Hugenholtz J,Sybesma W

doi

10.1128/aem.70.5.3146-3148.2004

keywords:

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

3146-8

issue

5

eissn

0099-2240

issn

1098-5336

journal_volume

70

pub_type

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