Educational interest of systematic collection of adverse drug reactions (with regard to an experience of nearly 20 years).

abstract：AIM:To study the influence of media attention about statins and ADRs on the level of disproportionality, expressed as the reporting odds ratio (ROR) for statins in the Lareb database, based on patients' reports. METHODS:Patient reports about statins, before and after the broadcast of a consumer programme about statins...

journal_title：Pharmacoepidemiology and drug safety

authors： van Hunsel F,van Puijenbroek E,de Jong-van den Berg L,van Grootheest K

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:To examine the association between maternal use of beta-2-adrenergic agonists (β2AAs) and the risk of epilepsy in offspring. METHODS:A nationwide retrospective cohort study was performed based on Danish registries. Children of mothers who used β2AAs during pregnancy were allocated to the exposed group and othe...

journal_title：Pharmacoepidemiology and drug safety

authors： Chen J,Liang H,Miao M,Su X,Yang F,Thomsen RW,Yuan W,Li J

更新日期：2018-11-01 00:00:00

abstract：PURPOSE:The aim of the present study was to determine whether community pharmacists recommend appropriate medications and give valid information to pregnant women. METHODS:A total of 163 community pharmacists randomly selected in the Midi-Pyrénées area were interviewed by means of an open questionnaire. Ten scenarios ...

journal_title：Pharmacoepidemiology and drug safety

authors： Damase-Michel C,Vié C,Lacroix I,Lapeyre-Mestre M,Montastruc JL

更新日期：2004-10-01 00:00:00

abstract：PURPOSE:Drug-induced liver injury (DILI) is one of the primary targets for pharmacovigilance using medical information databases (MIDs). Because of diagnostic complexity, a standardized method for identifying DILI using MIDs has not yet been established. We applied the Digestive Disease Week Japan 2004 (DDW-J) scale, a...

journal_title：Pharmacoepidemiology and drug safety

authors： Hanatani T,Sai K,Tohkin M,Segawa K,Kimura M,Hori K,Kawakami J,Saito Y

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:This paper introduces an improved tool for designing matched-pairs randomized trials. The tool allows the incorporation of clinical and other knowledge regarding the relative importance of variables used in matching and allows for multiple types of missing data. The method is illustrated in the context of a clu...

journal_title：Pharmacoepidemiology and drug safety

authors： Greevy RA Jr,Grijalva CG,Roumie CL,Beck C,Hung AM,Murff HJ,Liu X,Griffin MR

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:Days supply (prescription duration) values are commonly used to estimate drug exposure and quantify adherence to therapy, yet accuracy is not routinely assessed, and potential inaccurate reporting has been previously identified. We examined the impact of cleaning days supply values on the measurement of adheren...

journal_title：Pharmacoepidemiology and drug safety

authors： Burden AM,Paterson JM,Gruneir A,Cadarette SM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess the validity of dispensed prescription to classify exposure to medications used episodically during pregnancy, and to explore individual trajectories of episodic medication use across pregnancy, using triptans for migraine as the motivating example. METHODS:We compared self-reported triptan use durin...

journal_title：Pharmacoepidemiology and drug safety

authors： Harris GE,Wood M,Nordeng H

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To develop and validate an algorithm to identify preterm infants in the absence of birth certificates within Medicaid data. METHODS:Medicaid fee-for-service claims data from Florida (FL) and Texas (TX) were linked to vital statistics data for infants who were continuously eligible during the first 3 months fol...

journal_title：Pharmacoepidemiology and drug safety

authors： Eworuke E,Hampp C,Saidi A,Winterstein AG

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:This study describes the use of psychotropic drugs in a sample of eight Italian psychiatric hospitals. METHODS:A cross-sectional approach was used to collect information about sociodemographic and clinical characteristics of the inpatient population, and about medications prescribed. Prescribing behaviour in...

journal_title：Pharmacoepidemiology and drug safety

authors： Barbui C,D'Avanzo B,Frattura L,Saraceno B

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:To assess the prevalence of adverse drug reactions (ADRs) occurring in patients with Alzheimer's disease (AD) or other dementia in France. METHODS:A cross-sectional multicentre study was conducted by the French network of the 31 regional pharmacovigilance centres on a given day. The subjects were selected by r...

journal_title：Pharmacoepidemiology and drug safety

authors： Laroche ML,Perault-Pochat MC,Ingrand I,Merle L,Kreft-Jais C,Castot-Villepelet A,Durrieu G,Gras V,Guy C,Jean-Pastor MJ,Jonville-Béra AP,Merlet-Chicoine I,Miremont-Salamé G,Nourhashemi F,Charmes JP,French Centres of Pharmacov

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Little is known about opioid use after bariatric surgery among patients who did not use opioids chronically before surgery. Our purpose was to determine opioid use the year after bariatric surgery among patients who did not use opioids chronically pre-surgery and to identify pre-surgery characteristics associat...

journal_title：Pharmacoepidemiology and drug safety

authors： Raebel MA,Newcomer SR,Bayliss EA,Boudreau D,DeBar L,Elliott TE,Ahmed AT,Pawloski PA,Fisher D,Toh S,Donahoo WT

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Pre-licensure studies have limited ability to detect rare adverse events (AEs) to vaccines, requiring timely post-licensure studies. With the increasing availability of electronic health records (EHR) near real-time vaccine safety surveillance using these data has emerged as an option. We reviewed methods curre...

journal_title：Pharmacoepidemiology and drug safety

authors： Leite A,Andrews NJ,Thomas SL

更新日期：2016-03-01 00:00:00

abstract：:When a biological hypothesis of causal effect can be inferred, the hypothesis can sometimes be tested in the selfsame database that gave rise to the study data from which the hypothesis grew. Valid testing happens when the inferred biological hypothesis has scientific implications that predict new relations between ob...

journal_title：Pharmacoepidemiology and drug safety

authors： Walker AM

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Stimulants and atomoxetine should generally not be used or used only with caution in adults with pre-existing cardiovascular conditions. The extent to which pre-existing cardiovascular conditions influence initiation of these ADHD medications in adults is not known. METHODS:We performed a retrospective coho...

journal_title：Pharmacoepidemiology and drug safety

authors： Gerhard T,Winterstein AG,Olfson M,Huang C,Saidi A,Crystal S

更新日期：2010-05-01 00:00:00

abstract：:Sixteen pathologically confirmed and 14 suspected cases of a new disease entity, fibrosing colonopathy, have been described in the UK and the US in children with cystic fibrosis since 1991. The patterns of use of pancreatic enzyme supplements in cases were compared with use in controls and in the market, in the 2 year...

journal_title：Pharmacoepidemiology and drug safety

authors： Bakowski MT,Prescott P

更新日期：1997-09-01 00:00:00

abstract：PURPOSE:To compare the frequency of adverse drug reactions (ADRs) recorded by doctors with perceived ADRs reported by patients during hospitalization and post-discharge and to compare both to formal reporting in Thailand. SETTING:Tertiary teaching hospital, North-East Thailand. METHODS:Over a 6-month period doctors w...

journal_title：Pharmacoepidemiology and drug safety

authors： Jarernsiripornkul N,Kakaew W,Loalukkana W,Krska J

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:To investigate the occurrence of adverse drug reactions (ADRs) and associated risk factors in a pediatric hospital in northeast Brazil, from August to December 2001. SUBJECTS/SETTING:Two hundred seventy two patients hospitalized for more than 24 hours. METHODS:Prospective cohort study. Daily visits were perfo...

journal_title：Pharmacoepidemiology and drug safety

authors： dos Santos DB,Coelho HL

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Current guidelines for the empiric treatment of uncomplicated urinary tract infection in women recommend that first-line trimethoprim-sulfamethoxazole (TMP-SMX) or ofloxacin be given for 3 days and nitrofurantoin for 5 days. Increasing the duration of treatment raises costs, and perhaps, the incidence of adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kahan NR,Chinitz DP,Kahan E

更新日期：2004-04-01 00:00:00

abstract：PURPOSE:Our aim was to describe and assess the medicinal products and doses used for euthanasia in a series of cases, identified within an epidemiological death certificate study in Belgium, where euthanasia was until recently legally forbidden and where guidelines for euthanasia are not available. METHODS:In a random...

journal_title：Pharmacoepidemiology and drug safety

authors： Vander Stichele RH,Bilsen JJ,Bernheim JL,Mortier F,Deliens L

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:This study examined recent trends and correlates of prescription opioid use and long-term use in the United States. METHODS:Data were from 47 356 adult participants of National Health and Nutrition Survey from 1999-2000 to 2013-2014. Participants were asked about prescription medications used in the past 30 da...

journal_title：Pharmacoepidemiology and drug safety

authors： Mojtabai R

更新日期：2018-05-01 00:00:00

abstract：PURPOSE:To characterize the nature of a heparin contaminant's clinical effects in cases reported to the Adverse Event Reporting System (AERS). The FDA received reports of heparin-associated adverse events (AEs) starting in late 2007-early 2008 during a national investigation of allergic-type events. The investigation i...

journal_title：Pharmacoepidemiology and drug safety

authors： McMahon AW,Pratt RG,Hammad TA,Kozlowski S,Zhou E,Lu S,Kulick CG,Mallick T,Dal Pan G

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Outcome misclassification may occur in observational studies using administrative databases. We evaluated a two-step multiple imputation approach based on complementary internal validation data obtained from two subsamples of study participants to reduce bias in hazard ratio (HR) estimates in Cox regressions....

journal_title：Pharmacoepidemiology and drug safety

authors： Ni J,Leong A,Dasgupta K,Rahme E

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:Estimating drug effectiveness and safety among older adults in population-based studies using administrative health care claims can be hampered by unmeasured confounding as a result of frailty. A claims-based algorithm that identifies patients likely to be dependent, a proxy for frailty, may improve confounding...

journal_title：Pharmacoepidemiology and drug safety

authors： Faurot KR,Jonsson Funk M,Pate V,Brookhart MA,Patrick A,Hanson LC,Castillo WC,Stürmer T

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:A recent regulatory warning and case reports have described the development of muscle complications with the use of 5-α reductase inhibitors (5ARIs). We wished to determine if there was a link between rhabdomyolysis and 5ARI usage. METHODS:We used a matched cohort design and linked administrative data from the...

journal_title：Pharmacoepidemiology and drug safety

authors： Welk B,McArthur E,Ordon M,Dirk J,Dixon S,Garg AX

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To assess the extent, characteristics and determinants of benzodiazepine prescription in outpatient Primary Health Care. METHODS:A clinical audit of a stratified random sample of Primary Health Care Centres in the seven islands and 1.6 million inhabitants region of 'Canarias' in Spain was carried out. From t...

journal_title：Pharmacoepidemiology and drug safety

authors： de las Cuevas C,Sanz E,de la Fuente JA,Cabrera C,Mateos A

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:Warfarin is commonly used among patients who receive influenza, pneumococcal, and tetanus and diphtheria toxoid vaccines, and persons on warfarin therapy may also receive Hepatitis A vaccine. There has been concern that vaccinations could potentially alter coagulation parameters in patients on warfarin therapy....

journal_title：Pharmacoepidemiology and drug safety

authors： Jackson ML,Nelson JC,Chen RT,Davis RL,Jackson LA,Vaccine Safety Datalink investigators.

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:In post-marketing drug safety surveillance, data mining can potentially detect rare but serious adverse events. Assessing an entire collection of drug-event pairs is traditionally performed on a predefined level of granularity. It is unknown a priori whether a drug causes a very specific or a set of related adv...

journal_title：Pharmacoepidemiology and drug safety

authors： Kulldorff M,Dashevsky I,Avery TR,Chan AK,Davis RL,Graham D,Platt R,Andrade SE,Boudreau D,Gunter MJ,Herrinton LJ,Pawloski PA,Raebel MA,Roblin D,Brown JS

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Risk assessment for natural health products (NHPs) may not be evaluated similarly to therapeutic products by Health Canada in terms of notification of harms to consumers and health professionals. In this descriptive study, we evaluated risk communications (RCs) issued by Health Canada for NHPs and for therapeut...

journal_title：Pharmacoepidemiology and drug safety

authors： Bateman J,Charrois TL,Gardiner P,Vohra S

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Drug induced Torsades de Pointes (TdP) is a major concern for new drugs seeking regulatory approval. Prolongation of QT intervals greater than 60 millisecond or to longer than 500 millisecond in an individual patient has been considered to be associated with a higher risk. The purpose of this study is to identi...

journal_title：Pharmacoepidemiology and drug safety

authors： Lin YL,Kung MF

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Tramadol is a weak opioid analgesic, which is generally considered to be safe. However, conflicting data exist on the dependence potential of tramadol. OBJECTIVE:The aim of this study was to investigate occurrence of tramadol dependence and associated risk factors using spontaneously reported adverse drug r...

journal_title：Pharmacoepidemiology and drug safety

authors： Tjäderborn M,Jönsson AK,Ahlner J,Hägg S

更新日期：2009-12-01 00:00:00