当前位置： SCI文献检索 > JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA期刊下所有文献 > Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery.

Comparison of epsilon aminocaproic acid and tranexamic acid in pediatric cardiac surgery.

Abstract：

OBJECTIVE:This study compared the efficacy of aminocaproic acid and tranexamic acid in reducing postoperative blood loss, as well as blood and blood product requirements in children with cyanotic congenital heart disease. DESIGN:A prospective randomized study. SETTING:Cardiac center of a tertiary care, referral hospital. PARTICIPANTS:One hundred fifty children in the age group of 2 months to 14.5 years with cyanotic congenital heart disease undergoing corrective surgery on cardiopulmonary bypass (CPB). INTERVENTIONS:Patients were randomized into 3 groups. Group A was given aminocaproic acid in a dose of 100 mg/kg after anesthetic induction, 100 mg/kg on CPB and 100 mg/kg after protamine. Group T was given tranexamic acid, 10 mg/kg, after anesthetic induction, 10 mg/kg on CPB, and 10 mg/kg after protamine. Group C was the control group. MAIN RESULT:Control group had the longest sternal closure time, maximum blood loss at 24 hours, and maximum requirements of blood and blood products. Among the 2 groups given antifibrinolytics, there was no significant difference in postoperative blood loss, blood and product requirement, and reexploration rates. CONCLUSION:Aminocaproic acid and tranexamic acid are equally effective in reducing postoperative blood loss, as well as blood and blood product requirements in children with cyanotic heart disease undergoing corrective surgery as compared with the control group.

journal_name

J Cardiothorac Vasc Anesth

journal_title

Journal of cardiothoracic and vascular anesthesia

authors

Chauhan S,Das SN,Bisoi A,Kale S,Kiran U

doi

10.1053/j.jvca.2004.01.016

keywords:

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

141-3

issue

2

eissn

1053-0770

issn

1532-8422

pii

S1053077004000291

journal_volume

18

pub_type

临床试验,杂志文章,随机对照试验

相关文献

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA文献大全
  • The Impact of Initiation of an Intensivist-Led Patient Management Protocol on Outcomes After Cardiac Surgery.

    abstract：OBJECTIVES:Prolonged intensive care unit stay after cardiac surgery is associated with high mortality. The aim of this study was to evaluate the impact of the introduction of a quality improvement program under the supervision of an intensivist on the long-term mortality of high-risk patients with prolonged intensive c...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.12.048

    authors： Kogan A,Kassif Y,Frogel J,Levin S,Ram E,Peled Y,Raanani E,Sternik L

    更新日期：2021-01-04 00:00:00

  • Left atrial V waves following mitral valve replacement are not specific for significant mitral regurgitation.

    abstract：:Left atrial or pulmonary capillary wedge pressure V waves are used immediately after mitral valve replacement to evaluate valve competence. However, their correlation with hemodynamically significant regurgitation has not been established. Transesophageal echocardiography (TEE) was used to prospectively examine whethe...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/1053-0770(91)90035-r

    authors： Risk SC,D'Ambra MN,Griffin B,Fine R,O'Shea JP

    更新日期：1992-02-01 00:00:00

  • Long-term outcome of patients with perioperative myocardial infarction as diagnosed by troponin I after routine surgical coronary artery revascularization.

    abstract：OBJECTIVE:Diagnosis of perioperative myocardial infarction (P-MI) after coronary artery bypass graft (CABG) surgery traditionally relied on a combination of electrocardiographic and enzyme assay changes. Patients with Q-wave P-MIs who survive to hospital discharge have a poorer long-term prognosis. Troponin assays are ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2006.01.015

    authors： Riedel BJ,Grattan A,Martin CB,Gal J,Shaw AD,Royston D

    更新日期：2006-12-01 00:00:00

  • Femoral artery pressures are more reliable than radial artery pressures on initiation of cardiopulmonary bypass.

    abstract：OBJECTIVE:To compare radial and femoral artery perfusion pressure during initiation and various stages of cardiopulmonary bypass (CPB). DESIGN:Prospective study. SETTING:The cardiac center of a tertiary referral teaching institute. PARTICIPANTS:Sixty consecutive patients of all ages undergoing a variety of cardiac o...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：

    authors： Chauhan S,Saxena N,Mehrotra S,Rao BH,Sahu M

    更新日期：2000-06-01 00:00:00

  • A practical approach to echocardiographic assessment of perioperative diastolic dysfunction.

    abstract：:The Doppler assessment of diastolic dysfunction (DD) is not part of a standard comprehensive intraoperative echocardiographic examination. Although the reasons may be many, the lack of a simplified algorithm for the assessment of DD specific to the perioperative arena, the implications of this diagnosis on clinical ca...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,评审

    doi：10.1053/j.jvca.2012.07.012

    authors： Mahmood F,Jainandunsing J,Matyal R

    更新日期：2012-12-01 00:00:00

  • Cardiorespiratory changes in patients undergoing pulmonary resection using different anesthetic management techniques.

    abstract：OBJECTIVE:Pulmonary resection may be associated with considerable alterations of the cardiorespiratory system. The ideal anesthetic regimen for these patients is not yet definitely determined. DESIGN:Prospective, randomized study. SETTING:Single-institutional, clinical investigation in a thoracic anesthesia departmen...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s1053-0770(96)80045-0

    authors： Boldt J,Müller M,Uphus D,Padberg W,Hempelmann G

    更新日期：1996-12-01 00:00:00

  • Impact of Intubation Time on Survival following Coronary Artery Bypass Grafting: Insights from the Surgical Treatment for Ischemic Heart Failure (STICH) Trial.

    abstract：OBJECTIVE:The authors aimed to assess determinants of intubation time and evaluate its impact on 30-day and 1-year postoperative survival in Surgical Treatment for Ischemic Heart Failure (STICH) trial patients. DESIGN, SETTING, PARTICIPANTS, AND INTERVENTIONS:A multivariable Cox proportional hazards model was used amo...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2017.12.038

    authors： Bouabdallaoui N,Stevens SR,Doenst T,Wrobel K,Bouchard D,Deja MA,Michler RE,Chua YL,Kalil RAK,Selzman CH,Daly RC,Sun B,Djokovic LT,Sopko G,Velazquez EJ,Rouleau JL,Lee KL,Al-Khalidi HR,STICH Trial Investigators.

    更新日期：2018-06-01 00:00:00

  • Outcomes of Infant Cardiac Surgery for Congenital Heart Disease Concomitant With Persistent Pneumonia: A Retrospective Cohort Study.

    abstract：OBJECTIVES:There is still controversy about whether an infant should have cardiac surgery concomitant with ongoing persistent pneumonia. This study analyzes the outcome of surgical treatment for infants with left-to-right shunt congenital heart disease accompanied with persistent pneumonia and discusses the perioperati...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2018.05.039

    authors： Luo H,Qin G,Wang L,Ye Z,Pan Y,Huang L,Luo W,Guo Q,Peng Y,Wang E

    更新日期：2019-02-01 00:00:00

  • Total intravenous anesthesia with ketamine for pediatric interventional cardiac procedures.

    abstract：OBJECTIVE:To evaluate the safety and efficacy of ketamine in pediatric patients undergoing interventional cardiac procedures. DESIGN:A retrospective clinical study. SETTING:A single, tertiary referral center. PARTICIPANTS:Patients (n = 107) undergoing interventional cardiac procedures between July 1996 and July 1998...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/s1053-0770(00)90053-3

    authors： Singh A,Girotra S,Mehta Y,Radhakrishnan S,Shrivastava S

    更新日期：2000-02-01 00:00:00

  • Real-time measurement of rectal mucosal microcirculation during cardiopulmonary bypass.

    abstract：OBJECTIVES:Mesenteric ischemia is still a fatal event after cardiac procedures. No adequate intraoperative methods are available to monitor the gastrointestinal mucosal microcirculation in real-time conditions. The aim of the study was to assess a newly designed microprobe using laser Doppler flowmetry and remission sp...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2014.07.003

    authors： Kiessling AH,Reyher C,Philipp M,Beiras-Fernandez A,Moritz A

    更新日期：2015-02-01 00:00:00

  • Left Atrial Appendage Velocity as a Predictor of Atrial Fibrillation After Cardiac Surgery.

    abstract：OBJECTIVE:To determine if there is an association between left atrial appendage velocity and the development of postoperative atrial fibrillation (POAF). DESIGN:Single institution retrospective study performed between January 2013 and December 2013. SETTING:Single-institution, university hospital. PARTICIPANTS:Five ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2015.08.023

    authors： Ngai J,Leonard J,Echevarria G,Neuburger P,Applebaum R

    更新日期：2016-04-01 00:00:00

  • Role of magnesium sulfate in postoperative pain management for patients undergoing thoracotomy.

    abstract：OBJECTIVE:The purpose of this study was to investigate the effect of magnesium sulfate on pain management for post-thoracotomy patients. DESIGN:A prospective, randomized, controlled clinical study. SETTING:University hospital. PARTICIPANTS:Twenty-four patients undergoing thoracotomy. INTERVENTIONS:After thoracotomy...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,随机对照试验

    doi：10.1053/j.jvca.2006.11.013

    authors： Ozcan PE,Tugrul S,Senturk NM,Uludag E,Cakar N,Telci L,Esen F

    更新日期：2007-12-01 00:00:00

  • Preoperative Invasive Hemodynamic Determinants of Survival Among Patients Undergoing Aortic or Mitral Valve Surgery.

    abstract：OBJECTIVES:To evaluate the association of preoperative invasive hemodynamic parameters with mortality in valvular heart surgery. DESIGN:Retrospective cohort study. SETTING:Single tertiary academic medical center. PARTICIPANTS:A total of 382 patients who underwent preoperative right and/or left heart catheterization ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2017.09.041

    authors： Zhuo DX,Bilchick KC,Mazimba S

    更新日期：2018-06-01 00:00:00

  • Gastric intramucosal pH: a predictor of survival in cardiac surgery patients with low cardiac output?

    abstract：OBJECTIVE:To assess the value of gastric intramucosal pH measurement in patients with low output after cardiac surgery. DESIGN:Prospective clinical study. SETTING:University hospital. PARTICIPANTS:Fifteen patients with low output after cardiac surgery were included. Those who survived the first postoperative day (n ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/s1053-0770(97)90211-1

    authors： Böhrer H,Schmidt H,Motsch J,Gust R,Bach A,Martin E

    更新日期：1997-04-01 00:00:00

  • Exogenous surfactant may improve oxygenation but not mortality in adult patients with acute lung injury/acute respiratory distress syndrome: a meta-analysis of 9 clinical trials.

    abstract：OBJECTIVE:To evaluate whether exogenous surfactant therapy may be useful in adult patients with acute lung injury or acute respiratory distress syndrome, using a meta-analysis of published clinical trials. DESIGN:A comprehensive literature search was performed to identify all randomized clinical trials examining the e...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,meta分析

    doi：10.1053/j.jvca.2011.11.006

    authors： Meng H,Sun Y,Lu J,Fu S,Meng Z,Scott M,Li Q

    更新日期：2012-10-01 00:00:00

  • Methylprednisolone does not influence endotoxin translocation during cardiopulmonary bypass.

    abstract：:This study investigated whether the prophylactic administration of methylprednisolone sodium succinate (MPSS) could prevent an increase in plasma endotoxin levels during cardiac surgery with cardiopulmonary bypass. MPSS (1 g/patient) or saline was given intravenously with induction in the steroid (n = 6) and control (...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/1053-0770(93)90113-y

    authors： Karlstad MD,Patteson SK,Guszcza JA,Langdon R,Chesney JT

    更新日期：1993-02-01 00:00:00

  • Bilateral Erector Spinae Blocks Decrease Perioperative Opioid Use After Pediatric Cardiac Surgery.

    abstract：OBJECTIVE:The present study examined the feasibility and efficacy of continuous bilateral erector spinae blocks for post-sternotomy pain in pediatric cardiac surgery. DESIGN:Prospective cohort study; patients were retrospectively matched 1:2 to control patients. Conditional logistic regression was used to compare dich...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.10.009

    authors： Roy N,Brown ML,Parra MF,Sleeper LA,Alrayashi W,Nasr VG,Eklund SE,Cravero JP,Del Nido PJ,Brusseau R

    更新日期：2020-10-12 00:00:00

  • Modified rapid shallow breathing index adjusted with anthropometric parameters increases predictive power for extubation failure compared with the unmodified index in postcardiac surgery patients.

    abstract：OBJECTIVE:The aim of this study was to determine the best predictors of successful extubation after cardiac surgery, by modifying the rapid shallow breathing index (RSBI) based on patients' anthropometric parameters. DESIGN:Single-center prospective observational study. SETTING:Two general intensive care units at a s...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2014.06.022

    authors： Takaki S,Kadiman SB,Tahir SS,Ariff MH,Kurahashi K,Goto T

    更新日期：2015-02-01 00:00:00

  • Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Vascular Surgery.

    abstract：OBJECTIVE:The National Inpatient Sample (NIS) from years 2010 through 2012 was utilized to determine the incidence, predictive risk factors, and outcomes of heparin-induced thrombocytopenia (HIT) in patients undergoing vascular surgery. DESIGN:Retrospective population-based study. SETTING:Data from the National Inpat...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2017.05.024

    authors： Chaudhry R,Wegner R,Zaki JF,Pednekar G,Tse A,Kukreja N,Grewal N,Williams GW

    更新日期：2017-10-01 00:00:00

  • A cadaver study to measure the adult glottis and subglottis: defining a problem associated with the use of double-lumen tubes.

    abstract：OBJECTIVE:To test the hypothesis that the adult cricoid diameter is the same or less than that of the glottis. DESIGN:Prospective. SETTING:A city mortuary. PARTICIPANTS:Adult cadavers undergoing autopsy. INTERVENTIONS:After removal of the organs, the trachea was opened above the first ring to allow access to the cr...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/jcan.2002.31066

    authors： Seymour AH,Prakash N

    更新日期：2002-04-01 00:00:00

  • Multidisciplinary approach to transvenous lead extraction: a single center's experience.

    abstract：OBJECTIVE:To evaluate the success and complication rates of a single center's multidisciplinary approach to transvenous lead extraction. SETTING:One university hospital. PARTICIPANTS:One hundred ninety-five patients scheduled for transvenous lead extraction. INTERVENTIONS:A multidisciplinary approach to transvenous ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2014.11.010

    authors： Maus TM,Shurter J,Nguyen L,Birgersdotter-Green U,Pretorius V

    更新日期：2015-04-01 00:00:00

  • Hydroxocobalamin Versus Methylene Blue for Vasoplegic Syndrome in Cardiothoracic Surgery: A Retrospective Cohort.

    abstract：OBJECTIVE:To compare methylene blue with hydroxocobalamin as a rescue therapy for vasoplegic syndrome. DESIGN:Retrospective cohort. SETTING:Academic medical center. PARTICIPANTS:Patients undergoing cardiothoracic surgery treated for vasoplegic syndrome. INTERVENTIONS:Thirty-five patients were treated with methylene...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.01.033

    authors： Furnish C,Mueller SW,Kiser TH,Dufficy L,Sullivan B,Beyer JT

    更新日期：2020-07-01 00:00:00

  • Effects of hemodilution, blood loss, and consumption on hemostatic factor levels during cardiopulmonary bypass.

    abstract：OBJECTIVES:The purpose of this study was to determine quantitatively the effects of consumption, hemodilution, and blood loss on coagulation and fibrinolytic factor levels during cardiopulmonary bypass. DESIGN:A combination of measured levels of prothrombin, antithrombin, fibrinogen, plasminogen, and antiplasmin along...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2004.11.046

    authors： Chandler WL

    更新日期：2005-08-01 00:00:00

  • A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality.

    abstract：OBJECTIVE:Reducing mortality is a key target in critical care and perioperative medicine. The authors aimed to identify all nonsurgical interventions (drugs, techniques, strategies) shown by randomized trials to increase mortality in these clinical settings. DESIGN:A systematic review of the literature followed by a c...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2019.03.022

    authors： Sartini C,Lomivorotov V,Pisano A,Riha H,Baiardo Redaelli M,Lopez-Delgado JC,Pieri M,Hajjar L,Fominskiy E,Likhvantsev V,Cabrini L,Bradic N,Avancini D,Wang CY,Lembo R,Novikov M,Paternoster G,Gazivoda G,Alvaro G,Roasio

    更新日期：2019-10-01 00:00:00

  • Echocardiographic Predictors of Immediate Postoperative Outcomes in Patients With Severe Left Ventricular Systolic Dysfunction Undergoing On-Pump Coronary Artery Bypass Grafting.

    abstract：OBJECTIVES:The postoperative course following on-pump coronary artery bypass grafting (CABG) in patients with severe left ventricular (LV) systolic dysfunction is often unpredictable. Therefore, the aim of this study was to identify predictors of poor postoperative outcome in this subset of patients. DESIGN:Prospectiv...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2016.04.025

    authors： Jha AK,Malik V,Gharde P,Chauhan S,Kiran U,Hote MP

    更新日期：2017-02-01 00:00:00

  • Blood salvage in cardiac surgery.

    abstract：:The aim of this study was to evaluate blood salvage provided by an intraoperative blood recovery system (IBRS) and a mediastinal drainage blood recovery system (MBRS) during and after cardiac surgery. Sixty-six patients undergoing aortocoronary bypass surgery were randomly assigned to three groups of 22 patients each....

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/1053-0770(91)90119-e

    authors： Parrot D,Lançon JP,Merle JP,Rerolle A,Bernard A,Obadia JF,Caillard B

    更新日期：1991-10-01 00:00:00

  • The influence of propofol and midazolam/halothane anesthesia on hepatic SvO2 and gastric mucosal pH during cardiopulmonary bypass.

    abstract：OBJECTIVE:Because propofol is known to reduce vascular resistance, the objective of this study was to compare the indices of hepatosplanchnic circulation and oxygenation during cardiopulmonary bypass (CPB) in patients anesthetized with either propofol or midazolam/halothane. DESIGN:A prospective, randomized, nonblinde...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s1053-0770(98)90195-1

    authors： Christiansen CL,Ahlburg P,Jakobsen CJ,Andresen EB,Paulsen PK

    更新日期：1998-08-01 00:00:00

  • The Effect of Modified Ultrafiltration on Serum Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery.

    abstract：OBJECTIVE:The aim of this study was to investigate whether the use of modified ultrafiltration at the end of cardiopulmonary bypass for cardiac surgical procedures significantly changes vancomycin serum concentrations. DESIGN:Prospective study. SETTING:Single tertiary cardiac center. PARTICIPANTS:Twenty-six elective...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2018.06.004

    authors： Crimi E,Hernandez-Barajas D,Seller A,Ashton J,Martin M,Vasilopoulos T,Gravenstein N

    更新日期：2019-01-01 00:00:00

  • Tricuspid Regurgitation in Congestive Heart Failure: Management Strategies and Analysis of Outcomes.

    abstract：:Tricuspid regurgitation is a notable aspect of congestive heart failure and is linked with worse outcomes if untreated. Functional tricuspid regurgitation commonly is seen in patients with heart failure, particularly in patients presenting for surgical management, such as those for mechanical cardiac assist device imp...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,评审

    doi：10.1053/j.jvca.2020.06.022

    authors： Ramsdell GC,Nelson JA,Pislaru SV,Ramakrishna H

    更新日期：2020-06-12 00:00:00

  • Methicillin-resistant Staphylococcus species in a cardiac surgical intensive care unit: a 5-year experience.

    abstract：OBJECTIVES:Methicillin-resistant Staphylococcus is a growing problem in intensive care units (ICUs). The aim of this study was to describe the epidemiology of methicillin-resistant Staphylococcus isolates in a cardiac surgical ICU over a 5-year period and to determine the risk factors and outcome of this condition. ME...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2004.12.002

    authors： Zangrillo A,Landoni G,Fumagalli L,Bove T,Bellotti F,Sottocorna O,Roberti A,Marino G

    更新日期：2006-02-01 00:00:00