当前位置： SCI文献检索 > JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA期刊下所有文献 > Methylprednisolone does not influence endotoxin translocation during cardiopulmonary bypass.

Methylprednisolone does not influence endotoxin translocation during cardiopulmonary bypass.

Abstract：

:This study investigated whether the prophylactic administration of methylprednisolone sodium succinate (MPSS) could prevent an increase in plasma endotoxin levels during cardiac surgery with cardiopulmonary bypass. MPSS (1 g/patient) or saline was given intravenously with induction in the steroid (n = 6) and control (n = 7) groups, respectively. Blood samples were collected preinduction and postinduction, during and after cardiopulmonary bypass, and 1 and 24 hours postoperatively. Plasma endotoxin was determined by a chromogenic Limulus amebocyte lysate assay. There was an intraoperative increase in the level of plasma endotoxin that occurred primarily after initiation of cardiopulmonary bypass and removal of the aortic cross-clamp. Endotoxin at 1 and 24 hours postoperatively was lower than the peak intraoperative levels and approached the preinduction level in both groups. The pump prime and other administered fluids contained low levels of endotoxin that were at or below the preinduction or postinduction level of the patients. MPSS did not prevent or attenuate the degree of endotoxemia during cardiopulmonary bypass. The loss of normal gut mucosal barrier function during cardiopulmonary bypass may result in endotoxemia and/or bacterial translocation, either of which could initiate or contribute to postoperative complications.

journal_name

J Cardiothorac Vasc Anesth

journal_title

Journal of cardiothoracic and vascular anesthesia

authors

Karlstad MD,Patteson SK,Guszcza JA,Langdon R,Chesney JT

doi

10.1016/1053-0770(93)90113-y

subject

Has Abstract

pub_date

1993-02-01 00:00:00

pages

23-7

issue

1

eissn

1053-0770

issn

1532-8422

pii

1053-0770(93)90113-Y

journal_volume

7

pub_type

临床试验,杂志文章,随机对照试验

相关文献

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA文献大全
  • Paravertebral ropivacaine, 0.3%, and bupivacaine, 0.25%, provide similar pain relief after thoracotomy.

    abstract：OBJECTIVE:This study was designed to determine whether ropivacaine plus fentanyl was as effective as bupivacaine plus fentanyl in a continuous thoracic paravertebral block after posterolateral thoracotomy. DESIGN:Patients were randomly assigned in a blinded fashion to receive 1 of 2 solutions for paravertebral analges...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,随机对照试验

    doi：10.1053/j.jvca.2006.02.032

    authors： Navlet MG,Garutti I,Olmedilla L,Pérez-Peña JM,San Joaquin MT,Martinez-Ragues G,Gomez-Caro L

    更新日期：2006-10-01 00:00:00

  • Perioperative myocardial ischemia in carotid endarterectomy under cervical plexus block and prophylactic nitroglycerin infusion.

    abstract：:Perioperative myocardial ischemia was evaluated in 36 consecutive carotid endarterectomy procedures carried out on patients with a high (72.2%) prevalence of ischemic heart disease. The procedures were performed under cervical plexus block plus a prophylactic intravenous nitroglycerin infusion. Findings of myocardial ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/1053-0770(93)90002-3

    authors： Landesberg G,Erel J,Anner H,Eidelman LA,Weinmann E,Luria MH,Admon D,Assaf J,Sapoznikov D,Berlatzky Y

    更新日期：1993-06-01 00:00:00

  • Platelet-induced vasomotion of isolated canine coronary artery in the presence of halothane or isoflurane.

    abstract：:To determine the effect of 1.5 MAC of two volatile anesthetics (halothane and isoflurane) on platelet-induced contraction of canine coronary artery, isolated, denuded coronary rings were suspended between two stirrups, placed into organ chambers filled with an oxygenated Krebs-Ringer solution, and connected to an isom...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/1053-0770(94)90058-2

    authors： Blaise GA,Parent M,Laurin S,Omri A,Reader TA,Moutquin JM

    更新日期：1994-04-01 00:00:00

  • Activated Coagulation Time and Hepcon Protamine Titration Device to Manage Unfractionated Heparin During Cardiopulmonary Bypass in a Hemophilia A Patient on Emicizumab.

    abstract：:In the perioperative management of patients with hemophilia A, emicizumab prevents the accurate measurement of common clotting assays, including the activated clotting time (ACT), which is essential for high-dose heparin monitoring during cardiopulmonary bypass surgery. The authors describe the successful perioperativ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.08.058

    authors： Isaacs J,Welsby IJ,Schroder JN,Onwuemene OA

    更新日期：2020-08-27 00:00:00

  • Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol.

    abstract：OBJECTIVE:To evaluate reports from the published literature of all randomized clinical trials (RCT) comparing postoperative sedation with dexmedetomidine versus propofol in adult patients, after open cardiac surgery. DESIGN:A computerized search on Medline, EMBASE, Web of Science, and Agency for Healthcare Research an...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.10.022

    authors： Abowali HA,Paganini M,Enten G,Elbadawi A,Camporesi EM

    更新日期：2020-10-17 00:00:00

  • Measuring cardiac output in one-lung ventilation: a comparison of pulmonary artery and transpulmonary aortic measurements in pigs.

    abstract：OBJECTIVE:The agreement between cardiac output measurements via pulmonary artery thermodilution (CO[PA]) and transpulmonary aortic thermodilution (CO[AT]) during one-lung ventilation was studied. DESIGN:Animal study with repeated simultaneous measurements comparing 2 cardiac output measurement techniques. SETTING:Exp...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2004.01.026

    authors： Hüter L,Schwarzkopf K,Preussler NP,Gaser E,Schubert H,Karzai W,Schreiber T

    更新日期：2004-04-01 00:00:00

  • The Edmonton Frail Scale Improves the Prediction of 30-Day Mortality in Elderly Patients Undergoing Cardiac Surgery: A Prospective Observational Study.

    abstract：OBJECTIVES:To investigate whether the Edmonton Frail Scale (EFS), a multidimensional frailty assessment tool, improves the prediction of 30-day or in-hospital mortality over the use of the European System for Cardiac Outcome Risk Evaluation (EuroSCORE) II alone. DESIGN:Single-center prospective observational study. S...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2018.05.038

    authors： Amabili P,Wozolek A,Noirot I,Roediger L,Senard M,Donneau AF,Hubert MB,Brichant JF,Hans GA

    更新日期：2019-04-01 00:00:00

  • A Focused Transesophageal Echocardiography Protocol for Intraoperative Management During Orthotopic Liver Transplantation.

    abstract：OBJECTIVE:The value of a simplified, focused intraoperative transesophageal echocardiography (TEE) protocol in patients undergoing liver transplantation (LT) is unknown. We sought to create and assess a 5-view LT TEE examination focused on 5 prespecified common causes of hypotension during LT. DESIGN:Retrospective coh...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2020.01.028

    authors： Vanneman MW,Dalia AA,Crowley JC,Luchette KR,Chitilian HV,Shelton KT

    更新日期：2020-07-01 00:00:00

  • The operating surgeon is an independent predictor of chest tube drainage following cardiac surgery.

    abstract：OBJECTIVES:Bleeding into the chest is a major cause of blood transfusion and adverse outcomes following cardiac surgery. The authors investigated predictors of bleeding following cardiac surgery to identify potentially correctable factors. DESIGN:Data were retrieved from the medical records of patients undergoing card...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2013.09.010

    authors： Dixon B,Reid D,Collins M,Newcomb AE,Rosalion A,Yap CH,Santamaria JD,Campbell DJ

    更新日期：2014-04-01 00:00:00

  • Effects of levosimendan on left ventricular function: correlation with plasma concentrations in conscious dogs.

    abstract：OBJECTIVES:To test the hypothesis that the hemodynamic and left ventricular functional actions of levosimendan (Orion Pharmaceutica, Espoo, Finland), a new myofilament calcium sensitizer with phosphodiesterase-inhibiting properties, in conscious dogs are correlated with plasma concentrations of the drug measured with r...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/s1053-0770(97)90252-4

    authors： McGough MF,Pagel PS,Lowe D,Hettrick DA,Kersten JR,Warltier DC

    更新日期：1997-02-01 00:00:00

  • Blood conservation: the CEO perspective.

    abstract：:Hospital CEOs are concerned about more than just cost of services to their patients. The advancement of patient car along with maintaining or improving patient safety are also key elements to the CEO, to limit patient risks, hospital liability, and negative public relations. The CEO is accountable to the hospital staf...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2004.06.003

    authors： Morgan TO

    更新日期：2004-08-01 00:00:00

  • Effect of prostaglandin E1 on myocardial contractility in dogs anesthetized with halothane: load-independent and noninvasive assessment using transesophageal echocardiography.

    abstract：:The presence of an inotropic action of prostaglandin E1 (PGE1) in vivo is controversial, and there are conflicting results obtained by various indices of myocardial contractility. In this study, a direct effect of PGE1 on contractility was investigated in dogs by use of a load-independent contractile index: left ventr...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/1053-0770(92)90102-d

    authors： Kikura M,Ikeda T,Kazama T,Ikeda K

    更新日期：1992-10-01 00:00:00

  • Innovations in Preoperative Planning: Insights into Another Dimension Using 3D Printing for Cardiac Disease.

    abstract：:Two-dimensional visualization of complex congenital heart disease has limitations in that there is variation in the interpretation by different individuals. Three-dimensional printing technology has been in use for decades but is currently becoming more commonly used in the medical field. Congenital heart disease serv...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,评审

    doi：10.1053/j.jvca.2017.11.037

    authors： Farooqi KM,Mahmood F

    更新日期：2018-08-01 00:00:00

  • Hypothermic versus normothermic cardiopulmonary bypass in patients with valvular heart disease.

    abstract：OBJECTIVE:The aim of this study was to test the hypothesis that normothermic cardiopulmonary bypass (CPB) is as effective as hypothermic CPB in terms of cardiac protection (cTnI level) and outcome in patients with valvular heart disease. DESIGN:Prospective randomized study. SETTING:A tertiary cardiothoracic referral ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,随机对照试验

    doi：10.1053/j.jvca.2013.03.009

    authors： Lomivorotov VV,Shmirev VA,Efremov SM,Ponomarev DN,Moroz GB,Shahin DG,Kornilov IA,Shilova AN,Lomivorotov VN,Karaskov AM

    更新日期：2014-04-01 00:00:00

  • Impact of Intubation Time on Survival following Coronary Artery Bypass Grafting: Insights from the Surgical Treatment for Ischemic Heart Failure (STICH) Trial.

    abstract：OBJECTIVE:The authors aimed to assess determinants of intubation time and evaluate its impact on 30-day and 1-year postoperative survival in Surgical Treatment for Ischemic Heart Failure (STICH) trial patients. DESIGN, SETTING, PARTICIPANTS, AND INTERVENTIONS:A multivariable Cox proportional hazards model was used amo...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2017.12.038

    authors： Bouabdallaoui N,Stevens SR,Doenst T,Wrobel K,Bouchard D,Deja MA,Michler RE,Chua YL,Kalil RAK,Selzman CH,Daly RC,Sun B,Djokovic LT,Sopko G,Velazquez EJ,Rouleau JL,Lee KL,Al-Khalidi HR,STICH Trial Investigators.

    更新日期：2018-06-01 00:00:00

  • Laryngeal mask airway for therapeutic fiberoptic bronchoscopic procedures.

    abstract：:These cases illustrate the advantages of the laryngeal mask as compared with an endotracheal tube or oxygen face mask for selected patients undergoing therapeutic bronchoscopic procedures. The advantages include a larger internal diameter allowing easier passage of instruments, reduced work of breathing, lack of disco...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/s1053-0770(05)80017-5

    authors： Birmingham B,Mentzer SJ,Body SC

    更新日期：1996-06-01 00:00:00

  • Meta-Analysis of the Outcome After Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation in Adult Patients.

    abstract：OBJECTIVE:This study was planned to pool existing data on outcome and to evaluate the efficacy of postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) in adult patients. DESIGN:Systematic review of the literature and meta-analysis. SETTING:Multi-institutional study. PARTICIPANTS:Adult patients w...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,meta分析,评审

    doi：10.1053/j.jvca.2017.08.048

    authors： Biancari F,Perrotti A,Dalén M,Guerrieri M,Fiore A,Reichart D,Dell'Aquila AM,Gatti G,Ala-Kokko T,Kinnunen EM,Tauriainen T,Chocron S,Airaksinen JKE,Ruggieri VG,Brascia D

    更新日期：2018-06-01 00:00:00

  • Reactive oxygen species and mitochondrial adenosine triphosphate-regulated potassium channels mediate helium-induced preconditioning against myocardial infarction in vivo.

    abstract：OBJECTIVES:Helium produces preconditioning by activating prosurvival kinases, but the roles of reactive oxygen species (ROS) or mitochondrial adenosine triphosphate-regulated potassium (K(ATP)) channels in this process are unknown. The authors tested the hypothesis that ROS and mitochondrial K(ATP) channels mediate hel...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2008.04.005

    authors： Pagel PS,Krolikowski JG,Pratt PF Jr,Shim YH,Amour J,Warltier DC,Weihrauch D

    更新日期：2008-08-01 00:00:00

  • Effect of pretreatment with simvastatin on spinal cord ischemia-reperfusion injury in rats.

    abstract：OBJECTIVE:The aim of this study was to evaluate the pretreatment effect of simvastatin on spinal cord ischemia-reperfusion injury. DESIGN:Prospective, interventional study. SETTING:University research laboratory. PARTICIPANTS:Forty-five male Sprague-Dawley rats. INTERVENTIONS:Rats were treated with oral simvastatin...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2012.01.025

    authors： Hwang J,Han JI,Han S

    更新日期：2013-02-01 00:00:00

  • Anesthesia for percutaneous transcatheter closure of perimembranous ventricular septal defect.

    abstract：OBJECTIVE:To review the anesthetic management for percutaneous transcatheter closure of perimembranous ventricular septal defect (VSD) with an Amplatzer asymmetric occluder device and to highlight the hemodynamic effects and potential complications associated with its delivery. DESIGN:Retrospective review of prospecti...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2005.05.023

    authors： Kapoor MC,Sharma S,Sharma VK,Dugal JS,Singh C

    更新日期：2006-04-01 00:00:00

  • Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Vascular Surgery.

    abstract：OBJECTIVE:The National Inpatient Sample (NIS) from years 2010 through 2012 was utilized to determine the incidence, predictive risk factors, and outcomes of heparin-induced thrombocytopenia (HIT) in patients undergoing vascular surgery. DESIGN:Retrospective population-based study. SETTING:Data from the National Inpat...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2017.05.024

    authors： Chaudhry R,Wegner R,Zaki JF,Pednekar G,Tse A,Kukreja N,Grewal N,Williams GW

    更新日期：2017-10-01 00:00:00

  • Inadvertent Hypothermia After Procedural Sedation and Analgesia in a Cardiac Catheterization Laboratory: A Prospective Observational Study.

    abstract：OBJECTIVES:To identify the prevalence of and risk factors for inadvertent hypothermia after procedures performed with procedural sedation and analgesia in a cardiac catheterization laboratory. DESIGN:A single-center, prospective observational study. SETTING:A tertiary-care private hospital in Australia. PARTICIPANTS...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2015.06.002

    authors： Conway A,Kennedy W,Sutherland J

    更新日期：2015-10-01 00:00:00

  • Methicillin-resistant Staphylococcus species in a cardiac surgical intensive care unit: a 5-year experience.

    abstract：OBJECTIVES:Methicillin-resistant Staphylococcus is a growing problem in intensive care units (ICUs). The aim of this study was to describe the epidemiology of methicillin-resistant Staphylococcus isolates in a cardiac surgical ICU over a 5-year period and to determine the risk factors and outcome of this condition. ME...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2004.12.002

    authors： Zangrillo A,Landoni G,Fumagalli L,Bove T,Bellotti F,Sottocorna O,Roberti A,Marino G

    更新日期：2006-02-01 00:00:00

  • Markers of splanchnic perfusion and intestinal translocation of endotoxins during cardiopulmonary bypass: effects of dopamine and milrinone.

    abstract：OBJECTIVES:To investigate markers of splanchnic perfusion and the extent of endotoxemia during cardiopulmonary bypass (CPB) and to compare the effects of dopamine and milrinone on both splanchnic perfusion and endotoxemia. DESIGN:Prospective, randomized, blinded study. SETTING:University teaching hospital. PARTICIPA...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s1053-0770(99)90266-5

    authors： McNicol L,Andersen LW,Liu G,Doolan L,Baek L

    更新日期：1999-06-01 00:00:00

  • Comparison of minithoracotomy and conventional sternotomy approaches for valve surgery.

    abstract：OBJECTIVE:To compare patients undergoing valve surgery through a minithoracotomy approach with a matched group undergoing conventional valve surgery. DESIGN:Control study. SETTING:University hospital, single center. PARTICIPANTS:Forty-one consecutive patients scheduled for valve surgery by minithoracotomy approach w...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 临床试验,杂志文章

    doi：10.1016/s1053-0770(03)00051-x

    authors： de Vaumas C,Philip I,Daccache G,Depoix JP,Lecharny JB,Enguerand D,Desmonts JM

    更新日期：2003-06-01 00:00:00

  • Right Ventricular Systolic Performance Determined by 2D Speckle-Tracking Echocardiography and Acute Kidney Injury After Cardiac Surgery.

    abstract：OBJECTIVE:An association between central venous pressure and acute kidney injury (AKI) has been observed following cardiac surgery, but it is unknown whether this reflects intravascular volume status or impaired right ventricular (RV) myocardial performance. This study was performed to test the hypothesis that decrease...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2018.09.012

    authors： Yockelson SR,Heitner SB,Click S,Geleto G,Treggiari MM,Hutchens MP

    更新日期：2019-03-01 00:00:00

  • The Precision of Pulmonary Artery Catheter Bolus Thermodilution Cardiac Output Measurements Varies With the Clinical Situation.

    abstract：OBJECTIVE:To investigate the effects of ventilatory mode, injectate temperature, and clinical situation on the precision of cardiac output measurements. DESIGN:Randomized, prospective observational study. SETTING:Single university hospital. PARTICIPANTS:Forty patients undergoing planned cardiac surgery, receiving a ...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章,随机对照试验

    doi：10.1053/j.jvca.2014.12.016

    authors： Kirkeby-Garstad I,Trønnes H,Stenseth R,Sellevold OF,Aadahl P,Skogvoll E

    更新日期：2015-08-01 00:00:00

  • Adenosine diphosphate-induced single-platelet count aggregation and bleeding in clopidogrel-treated patients undergoing coronary artery bypass grafting.

    abstract：OBJECTIVES:To investigate the association between adenosine diphosphate (ADP)-induced platelet aggregation measured by single-platelet count testing and postoperative blood loss in clopidogrel-treated patients with acute coronary syndromes undergoing coronary artery bypass grafting (CABG). DESIGN:Prospective observati...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2013.10.007

    authors： Dalén M,van der Linden J,Holm M,Lindvall G,Ivert T

    更新日期：2014-04-01 00:00:00

  • Methylene blue does not neutralize heparin after cardiopulmonary bypass.

    abstract：OBJECTIVE:It was hypothesized that methylene blue could neutralize heparin in patients after cardiopulmonary bypass and become an alternative to protamine. DESIGN:This was a prospective unblinded study with patients serving as their own controls. SETTING PARTICIPANTS: A single, large university hospital. This study wa...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1016/s1053-0770(05)80007-2

    authors： Metz S,Horrow JC,Goel IP,Kuretu ML,Bellwoar C

    更新日期：1996-06-01 00:00:00

  • Outcomes of Infant Cardiac Surgery for Congenital Heart Disease Concomitant With Persistent Pneumonia: A Retrospective Cohort Study.

    abstract：OBJECTIVES:There is still controversy about whether an infant should have cardiac surgery concomitant with ongoing persistent pneumonia. This study analyzes the outcome of surgical treatment for infants with left-to-right shunt congenital heart disease accompanied with persistent pneumonia and discusses the perioperati...

    journal_title：Journal of cardiothoracic and vascular anesthesia

    pub_type： 杂志文章

    doi：10.1053/j.jvca.2018.05.039

    authors： Luo H,Qin G,Wang L,Ye Z,Pan Y,Huang L,Luo W,Guo Q,Peng Y,Wang E

    更新日期：2019-02-01 00:00:00