当前位置： SCI文献检索 > JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA期刊下所有文献 > Paravertebral ropivacaine, 0.3%, and bupivacaine, 0.25%, provide similar pain relief after thoracotomy.

Paravertebral ropivacaine, 0.3%, and bupivacaine, 0.25%, provide similar pain relief after thoracotomy.

Abstract：

OBJECTIVE:This study was designed to determine whether ropivacaine plus fentanyl was as effective as bupivacaine plus fentanyl in a continuous thoracic paravertebral block after posterolateral thoracotomy. DESIGN:Patients were randomly assigned in a blinded fashion to receive 1 of 2 solutions for paravertebral analgesia. SETTING:Multi-institutional university hospital. PARTICIPANTS:Sixty patients undergoing elective thoracotomy. INTERVENTIONS:A continuous paravertebral infusion of 0.1 mL/kg/h of either 0.3% ropivacaine/fentanyl, 3 microg/mL, or 0.25% bupivacaine/fentanyl, 3 microg/mL, was started on admission to the intensive care unit. MEASUREMENTS AND MAIN RESULTS:Pain scores (rest, deep breathing, and coughing), spirometry, subcutaneous opioids, or nonsteroidal anti-inflammatory drug consumption and adverse events were assessed for 48 hours. Both techniques provided adequate pain relief for the first 2 days after posterolateral thoracotomy. There were no differences between groups in pain scores at rest, coughing, or movement. There was an improvement of spirometry values between the first and second day in both groups. There were no differences in the requirements for rescue analgesia and side effects between groups. CONCLUSIONS:It is concluded that both bupivacaine, 0.25%, and ropivacaine, 0.3%, with fentanyl are equally effective for post-thoracotomy pain control when used via continuous paravertebral blockade.

journal_name

J Cardiothorac Vasc Anesth

journal_title

Journal of cardiothoracic and vascular anesthesia

authors

Navlet MG,Garutti I,Olmedilla L,Pérez-Peña JM,San Joaquin MT,Martinez-Ragues G,Gomez-Caro L

doi

10.1053/j.jvca.2006.02.032

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

644-7

issue

5

eissn

1053-0770

issn

1532-8422

pii

S1053-0770(06)00098-X

journal_volume

20

pub_type

杂志文章,随机对照试验

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