Advances in prostate cancer.

abstract：PURPOSE OF REVIEW:Human immunodeficiency virus infection is associated with an increased risk of non-Hodgkin lymphoma. Even with a decrease in AIDS-defining illnesses after the advent of highly active antiretroviral therapy, HIV-associated non-Hodgkin lymphoma remains an important problem. RECENT FINDINGS:Low CD4+ T-l...

journal_title：Current opinion in oncology

authors： Behler CM,Kaplan LD

更新日期：2006-09-01 00:00:00

abstract：:Over the past year, a number of important papers have appeared in the medical literature dealing with the chemotherapeutic management of gynecologic cancers. Among these papers, several studies have again demonstrated the superiority of platinum-based chemotherapy regimens for ovarian cancer compared with non-platinum...

journal_title：Current opinion in oncology

authors： Markman M

更新日期：1992-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Melanoma is the third most common metastatic brain tumor in the United States and is a major cause of morbidity and mortality. The development of more effective therapies for melanoma brain metastases is a major unmet clinical need and is summarized in this review. RECENT FINDINGS:Management strategi...

journal_title：Current opinion in oncology

authors： Tarhini AA,Agarwala SS

更新日期：2004-03-01 00:00:00

abstract：:Collaborative study groups have invested considerable effort in the last decade in defining the role of allogeneic and autologous bone marrow transplantation as consolidation treatment for first remission of acute myeloid leukemia in younger patients. These efforts have been able, more precisely, to quantitate the deg...

journal_title：Current opinion in oncology

authors： Burnett AK,Kell J

更新日期：2000-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The current status of postoperative adjuvant therapy for nonsmall cell lung cancer (NSCLC) is reviewed. RECENT FINDINGS:Cisplatin-based postoperative chemotherapy is a current standard of care for patients with stage II-III NSCLC who underwent complete resection. However, its benefit is limited. In t...

journal_title：Current opinion in oncology

authors： Mitsudomi T,Soh J

更新日期：2021-01-01 00:00:00

abstract：:The preclinical and clinical investigations of therapeutic approaches to melanoma have progressed significantly in the past year. This article reviews recently published information relevant to preclinical studies of the biologic function of stromal tissue, growth factors (and receptors), interferons, cytokines, and a...

journal_title：Current opinion in oncology

authors： Kirkwood JM

更新日期：1992-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Highlight recent data in lung and breast cancer leptomeningeal disease and address clinical trials that are open for patients. RECENT FINDINGS:Patients with lung and breast cancer leptomeningeal disease have survival outcomes of less than 1 year, despite advances in treatment strategy. Efforts to dev...

journal_title：Current opinion in oncology

authors： Gill CM,Brastianos PK

更新日期：2019-11-01 00:00:00

abstract：:The prophylactic or pre-emptive approach should help to restrict use of antibiotics and lead to better management of infection. It is clear that if effective pre-emptive therapy is available (be it as prophylaxis), the empiric additions of other agents should be taken into account and tailored accordingly. On the othe...

journal_title：Current opinion in oncology

authors： Klastersky J

更新日期：1996-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Significant advances have been made in the treatment of younger patients with acute myeloid leukemia over the past 3 decades, but prognosis in the elderly has remained dismal, with median survival times of only a few months. Although a small percentage of older patients may be cured by standard chemot...

journal_title：Current opinion in oncology

authors： Amadori S,Del Principe MI,Venditti A

更新日期：2014-11-01 00:00:00

abstract：:It is generally accepted that patients with chronic myelogenous leukemia in chronic phase under the age of 50 years who have HLA-identical siblings, should be offered bone marrow transplantation within the first year of diagnosis. The projected disease-free survival for these patients is 70% to 80% at 4 years, and mos...

journal_title：Current opinion in oncology

authors： Goldman JM

更新日期：1992-04-01 00:00:00

abstract：:The cancer patient often presents with fever and pulmonary infiltrates, in particular during the course of chemotherapy or after bone marrow transplantation. In these conditions, specific diagnoses are mainly related to an infective cause, but noninfectious processes, malignant or not, are also found alone or in combi...

journal_title：Current opinion in oncology

authors： Ninane V

更新日期：2001-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to update knowledge on therapy-related myeloid neoplasms (t-MN), taking into account the new 2008 WHO classification, new genome-wide approaches for the definition of susceptibility towards t-MN and the introduction of new more aggressive treatments in cancer patients. R...

journal_title：Current opinion in oncology

authors： Leone G,Fianchi L,Voso MT

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The effect of psychotherapy on the survival of cancer patients has been debated for the past 20 years, mainly due to contradictory findings in the studies published so far. Several reviews have been published, almost all of which criticize the methods used in the studies. In 2007, three replication st...

journal_title：Current opinion in oncology

authors： Boesen EH,Johansen C

更新日期：2008-07-01 00:00:00

abstract：:Twenty-three years after it was observed that successful treatment of Hodgkin's disease was associated with risk of a second malignancy related to treatment, the literature is maturing. Early reports of leukemia risk rising and falling between 5 and 10 years after treatment continue to be supported. The real problem i...

journal_title：Current opinion in oncology

authors： DeVita VT Jr

更新日期：1997-09-01 00:00:00

abstract：:The circumvention of P-glycoprotein function by pharmacologic agents is a major focus of clinical trials aimed at increasing the cytotoxicity of multidrug resistance-associated drugs, including doxorubicin. The success of this approach will likely depend on the clinical significance of P-glycoprotein expression, which...

journal_title：Current opinion in oncology

authors： Kruh GD,Goldstein LJ

更新日期：1993-11-01 00:00:00

abstract：:The clinical staging of bone tumors, even rare ones, has been much improved with the availability of better imaging techniques. Once diagnosis of a rare bone tumor has been made, close consultation between clinician, radiologist, and pathologist is essential for optimal treatment. Recent advances in the staging proced...

journal_title：Current opinion in oncology

authors： Dirix LY,Van Oosterom AT

更新日期：1991-08-01 00:00:00

abstract：:Enormous progress has been made in the last several years in delineating signal transduction pathways associated with cell proliferation and apoptosis. The components of these pathways, which include both oncogenes and tumor suppressors, may provide viable targets for therapeutic intervention for the treatment of canc...

journal_title：Current opinion in oncology

authors： Huang PS,Heimbrook DC

更新日期：1997-01-01 00:00:00

abstract：PURPOSE OF REVIEW:AIDS-related malignancies are an ongoing cause of mortality in individuals with HIV infection. In the HIV-negative setting, high-dose chemotherapy or stem cell transplantation is an option for patients with hematologic malignancies. Prior to the advent of effective HIV therapy, stem cell transplantati...

journal_title：Current opinion in oncology

authors： Krishnan A,Forman SJ

更新日期：2010-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The review focuses on the most recent advances in the diagnostic and prognostic work-up of adult acute lymphoblastic leukemia (ALL) and its implications in the clinical management of the disease. RECENT FINDINGS:ALL can be identified on the basis of morphologic, cytochemical and immunophenotypic crit...

journal_title：Current opinion in oncology

authors： Vitale A,Guarini A,Chiaretti S,Foà R

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Neuroendocrine tumors (previously referred to as carcinoids) are ill-understood, enigmatic malignancies that, although slow-growing compared with adenocarcinomas, can behave aggressively. In 2004, they comprised 1.25% of all malignancies; their incidence is increasing by approximately 6% per year. The...

journal_title：Current opinion in oncology

authors： Gustafsson BI,Kidd M,Modlin IM

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the most recent developments and implications in regard to isocitrate dehydrogenase mutations in chondrosarcoma, a disease in which currently available systemic therapies have proven inefficacious, with an emphasis on how disruption in normal cellular metabolism plays a role in on...

journal_title：Current opinion in oncology

authors： Azzi G,Velez M,Mathias-Machado MC

更新日期：2014-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an overview of recent updates in understanding the mechanisms by which glioblastoma cells interact with their cellular and molecular partners within the microenvironment. RECENT FINDINGS:We have now a better knowledge of the cell populations involved in Glioblastoma (GBM) invasio...

journal_title：Current opinion in oncology

authors： Chouleur T,Tremblay ML,Bikfalvi A

更新日期：2020-11-01 00:00:00

abstract：:Perioperative brachytherapy results in a better local control rate than surgery alone for extremity soft tissue sarcoma. Brachytherapy enables the delivery of a high radiation dose to a limited volume of tissue, allows the reduction of radiation treatment time, enables direct visualization of the tumor bed and surroun...

journal_title：Current opinion in oncology

authors： Ballo MT,Lee AK

更新日期：2003-07-01 00:00:00

abstract：:Over the past decade, high-dose chemotherapy followed by autologous bone marrow support (ABMS) has been employed with increasing frequency to treat patients with a variety of solid tumors. This paper explores the rationale and relevant clinical data for the use of this approach to treat patients with breast and ovaria...

journal_title：Current opinion in oncology

authors： Shpall EJ,Jones RB,Bearman S

更新日期：1994-03-01 00:00:00

abstract：:Over the past year, several research areas have been noteworthy. This article discusses decision making related to breast cancer treatment, the effects of treatment on measures of psychological distress, and studies related to quality-of-life among breast cancer patients. In addition, an area of continued interest inv...

journal_title：Current opinion in oncology

authors： Stefanek ME

更新日期：1993-11-01 00:00:00

abstract：PURPOSE OF REVIEW:This paper reviews the advances in surgery in head and neck cancer patients. RECENT FINDINGS:Sentinel node biopsy is a promising diagnostic technique to detect occult lymph node metastases, especially in oral carcinomas. Fludeoxyglucose-PET seems to be useful in detecting recurrent (laryngeal) carcin...

journal_title：Current opinion in oncology

authors： de Bree R,Leemans CR

更新日期：2010-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Current treatment modalities provide limited improvement in the natural course of lung cancer, and prognosis remains poor. Lung cancer is a malignancy with great molecular heterogeneity. The complexity of the signalling process leading to cancer cell proliferation and to the neoplastic phenotype suppo...

journal_title：Current opinion in oncology

authors： Cascone T,Gridelli C,Ciardiello F

更新日期：2007-03-01 00:00:00

abstract：:The interferons are complex proteins that have been widely tested as therapy for neoplastic diseases. Interferon (IFN)-alpha has been the most extensively studied in melanoma. It produces responses in about 16% of metastatic melanomas, about one third of which are complete. It has been combined with chemotherapy and b...

journal_title：Current opinion in oncology

authors： Agarwala SS,Kirkwood JM

更新日期：1996-03-01 00:00:00

abstract：:Recent publications dealing with the pathology of squamous carcinomas of the head and neck have been critically reviewed with particular reference to potential prognostic factors and improved methods for identifying nodal metastases. The topics covered include cytophotometry and proliferative patterns, molecular biolo...

journal_title：Current opinion in oncology

authors： Carter RL

更新日期：1993-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Relapse has become the leading cause of death following allogeneic hematopoietic stem cell transplantation (HSCT). Despite improved understanding of the biology that underlies the graft-versus-leukemia/tumor effect the relapse rate did not decrease over the past 20 years. In general, prognosis is poor...

journal_title：Current opinion in oncology

authors： Kröger N

更新日期：2011-03-01 00:00:00