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Inhibitors of stone formation in hypercalciuric children with and without stone disease.

Abstract：

:The extretion of two inhibitors of urinary stone formation (citrate, magnesium) was evaluated in 71 hypercalciuric children and 50 controls. Patients were classified into two groups: 42 nonstone former (NSF), 22 boys and 20 girls, 3-14 years old, and 29 stone formers (SF), 18 boys and 11 girls, 2.5-18 years old. Our study was unable to show significant differences in magnesium and citrate urinary outputs between controls and patient groups. The Mg/Ca ratio was found significantly lower in hypercalcuric children than in controls (p less than 0.001), but not between NSF and SF patients. Our data demonstrated that both NSF and SF groups had a significantly lower citrate/Ca ratio than controls (p less than 0.001), also it was lower in SF than in NSF (p less than 0.05). We found no significant difference in citrate excretion between boys and girls neither in patients nor in controls.

journal_name

Eur Urol

journal_title

European urology

authors

al-Qadreh A,Athanasopoulou H,Voskaki I

doi

10.1159/000474843

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

227-30

issue

3

eissn

0302-2838

issn

1873-7560

journal_volume

21

pub_type

杂志文章

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