Patterns of stromal elements in an implanted ureteric transitional cell carcinoma. An immunohistochemical and ultrastructural study.

Abstract:

:The results of the study of three implanted ureteric tumors from a primary transitional cell carcinoma of the renal pelvis are reported. Using both light microscopic immunohistochemistry and transmission electron microscopy, the stroma of the tumor showed consistent evidence for the production of at least its collagenous component by the neoplastic cells. Our findings argue with the notion that occasional fibroblasts and other cells of mesenchymal origin could play a major role in this phenomenon. Therefore, it seems plausible to suggest that what is happening in these tumors is similar to the behavior of malignant cells in scirrhous 'infiltrating' carcinoma of the breast and other sites.

journal_name

Eur Urol

journal_title

European urology

authors

Al-Zuhair AG,Al-Adnani MS,Al-Bader AA,Ek AG,Sabha M

doi

10.1159/000472741

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

79-82

issue

1-2

eissn

0302-2838

issn

1873-7560

journal_volume

13

pub_type

杂志文章
  • Retrocaval ureter.

    abstract::3 cases of retrocaval ureter (one of them presenting multiple urological anomalies) are discussed. In the presence of hydronephrosis, early operative reposition of the ureter is essential. Provided that the condition is diagnosed before extreme renal deterioration, the surgical repair can salvage remaining renal funct...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473971

    authors: Eidelman A,Yuval E,Simon D,Sibi Y

    更新日期:1978-01-01 00:00:00

  • Postchemotherapy retroperitoneal lymph node dissection in advanced germ cell tumours of the testis.

    abstract:OBJECTIVES:To review the role of postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) in patients with advanced testicular germ cell tumours (TGCT) with special attention towards the indication, surgical technique, and oncological outcome. METHODS:A structured review of the literature until May 2007 using...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2007.10.033

    authors: Heidenreich A,Thüer D,Polyakov S

    更新日期:2008-02-01 00:00:00

  • The 111 Study: A Single-arm, Phase 3 Trial Evaluating One Cycle of Bleomycin, Etoposide, and Cisplatin as Adjuvant Chemotherapy in High-risk, Stage 1 Nonseminomatous or Combined Germ Cell Tumours of the Testis.

    abstract:BACKGROUND:Standard management in the UK for high-risk stage 1 nonseminoma germ cell tumours of the testis (NSGCTT) is two cycles of adjuvant bleomycin, etoposide (360 mg/m2), and cisplatin (BE360P) chemotherapy, or surveillance. OBJECTIVE:To test whether one cycle of BE500P achieves similar recurrence rates to two cy...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2019.11.022

    authors: Cullen M,Huddart R,Joffe J,Gardiner D,Maynard L,Hutton P,Mazhar D,Shamash J,Wheater M,White J,Goubar A,Porta N,Witts S,Lewis R,Hall E,111 Trial Management Group.

    更新日期:2020-03-01 00:00:00

  • E-cigarettes and Urologic Health: A Collaborative Review of Toxicology, Epidemiology, and Potential Risks.

    abstract:CONTEXT:Use of electronic cigarettes (ECs) is on the rise in most high-income countries. Smoking conventional cigarettes is a known risk factor for urologic malignancy incidence, progression, and mortality, as well as for other urologic health indicators. The potential impact of EC use on urologic health is therefore o...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2016.12.022

    authors: Bourke L,Bauld L,Bullen C,Cumberbatch M,Giovannucci E,Islami F,McRobbie H,Silverman DT,Catto JWF

    更新日期:2017-06-01 00:00:00

  • Prevention and management of postprostatectomy sexual dysfunctions part 2: recovery and preservation of erectile function, sexual desire, and orgasmic function.

    abstract:CONTEXT:Sexual dysfunction is common in patients who undergo radical prostatectomy (RP) for prostate cancer (PCa). OBJECTIVE:Review the available literature concerning prevention of, and management strategies for, post-RP sexual dysfunction in terms of postoperative treatments for erectile function (EF), sexual desire...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2012.04.047

    authors: Salonia A,Burnett AL,Graefen M,Hatzimouratidis K,Montorsi F,Mulhall JP,Stief C

    更新日期:2012-08-01 00:00:00

  • The Impact of Design and Performance in Prostate-Specific Antigen Screening: Differences Between ERSPC Centers.

    abstract::The European Randomized study of Screening for Prostate Cancer (ERSPC) has shown a 20% relative reduction in prostate cancer mortality after 16yr [rate ratio (RR) 0.80], but centers varied by attendance, screen interval, biopsy compliance, contamination in the control arm, and treatments. We used a microsimulation mod...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2019.04.007

    authors: Heijnsdijk EAM,Adolfsson J,Auvinen A,Roobol MJ,Hugosson J,de Koning HJ

    更新日期:2019-09-01 00:00:00

  • A proposal for reclassification of the Fuhrman grading system in patients with clear cell renal cell carcinoma.

    abstract:BACKGROUND:The conventional Fuhrman grading system, which categorizes renal cell carcinoma (RCC) with grades I, II, III, and IV, is the most widely used predictor assessment of RCC cancer-specific mortality (CSM). OBJECTIVES:The aim of this study was to test the prognostic ability of simplified Fuhrman grading schemes...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2009.06.008

    authors: Sun M,Lughezzani G,Jeldres C,Isbarn H,Shariat SF,Arjane P,Widmer H,Pharand D,Latour M,Perrotte P,Patard JJ,Karakiewicz PI

    更新日期:2009-11-01 00:00:00

  • Case of duplication of the urethra in an adult male, presenting with symptoms of bladder outlet obstruction.

    abstract::Duplication of the urethra is a rare congenital anomaly, usually found in children and adolescents. The authors present a rare case of urethral duplication, presenting in a 58-yr-old man, with symptoms of bladder outlet obstruction. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2007.01.019

    authors: Slavov C,Donkov I,Popov E

    更新日期:2007-10-01 00:00:00

  • Epidemiological and clinical aspects of carcinoma in situ of the testis.

    abstract::Despite the high cure rate in men with testicular cancer, efforts should be made to diagnose the disease at the preinvasive stage. The disease, which affects young males, is potentially lethal. Furthermore, testicular neoplasia diagnosed at the stage of CIS can be cured without the negative impact on the life-quality ...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:

    authors: Giwercman A,von der Maase H,Skakkebaek NE

    更新日期:1993-01-01 00:00:00

  • Priapism of the clitoris.

    abstract::Priapism of the clitoris is a rare entity. A case of painful priapism is reported in a patient who had previously suffered a radical cystectomy for bladder carcinoma pT3-GIII, followed by local recurrence in the pelvis. From a symptomatic point of view she showed a good response to conservative treatment (analgesics a...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474228

    authors: Monllor J,Taño F,Arteaga PR,Galbis F

    更新日期:1996-01-01 00:00:00

  • 'Sting' procedure in the treatment of secondary reflux in children.

    abstract::The authors present their experience (24 children) with the endoscopic subureteral injection of Teflon paste in the correction of secondary vesicoureteral reflux: reimplantation failure; ureterocele; obstructive bladder; exstrophy; postchemocystitis, and Hutch's diverticulum. Of these 24 cases (31 refluxing ureters), ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000464067

    authors: Aubert D,Zoupanos G,Destuynder O,Hurez F

    更新日期:1990-01-01 00:00:00

  • Polyamines and prostatic carcinoma: clinical and therapeutic implications.

    abstract::The erythrocyte polyamines, spermidine and spermine, are known proliferation markers. The authors present their experience with polyamines and prostatic carcinoma. 229 patients with prostatic carcinoma had polyamine erythrocyte determination at diagnosis. Previous results confirmed a tendency to spermidine increase wi...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474279

    authors: Cipolla B,Guillé F,Moulinoux JP,Quemener V,Staerman F,Corbel L,Lobel B

    更新日期:1993-01-01 00:00:00

  • Pharmacokinetic profile of fosfomycin trometamol (Monuril).

    abstract::The kinetics of fosfomycin in serum and in urine was studied in 5 healthy volunteers after intravenous administration of disodium fosfomycin and after oral administration of trometamol fosfomycin at 50 mg/kg. The presence of secondary peaks in serum kinetics, more evident after oral administration, requires the use of...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472864

    authors: Segre G,Bianchi E,Cataldi A,Zannini G

    更新日期:1987-01-01 00:00:00

  • Age-adjusted incidence, mortality, and survival rates of stage-specific renal cell carcinoma in North America: a trend analysis.

    abstract:BACKGROUND:The rising incidence of renal cell carcinoma (RCC) has been largely attributed to the increasing use of imaging procedures. OBJECTIVE:Our aim was to examine stage-specific incidence, mortality, and survival trends of RCC in North America. DESIGN, SETTING, AND PARTICIPANTS:We computed age-adjusted incidence...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2010.10.029

    authors: Sun M,Thuret R,Abdollah F,Lughezzani G,Schmitges J,Tian Z,Shariat SF,Montorsi F,Patard JJ,Perrotte P,Karakiewicz PI

    更新日期:2011-01-01 00:00:00

  • A Specific Mapping Study Using Fluorescence Sentinel Lymph Node Detection in Patients with Intermediate- and High-risk Prostate Cancer Undergoing Extended Pelvic Lymph Node Dissection.

    abstract::Sentinel lymph node (SLN) detection techniques have the potential to change the standard of surgical care for patients with prostate cancer. We performed a lymphatic mapping study and determined the value of fluorescence SLN detection with indocyanine green (ICG) for the detection of lymph node metastases in intermedi...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.01.034

    authors: Nguyen DP,Huber PM,Metzger TA,Genitsch V,Schudel HH,Thalmann GN

    更新日期:2016-11-01 00:00:00

  • Stool Microbiome Profiling of Patients with Metastatic Renal Cell Carcinoma Receiving Anti-PD-1 Immune Checkpoint Inhibitors.

    abstract::Preclinical models and early clinical data suggest an interplay between the gut microbiome and response to immunotherapy in solid tumors including metastatic renal cell carcinoma (mRCC). We sought to characterize the stool microbiome of mRCC patients receiving a checkpoint inhibitor (CPI) and to assess treatment-relat...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2020.07.011

    authors: Salgia NJ,Bergerot PG,Maia MC,Dizman N,Hsu J,Gillece JD,Folkerts M,Reining L,Trent J,Highlander SK,Pal SK

    更新日期:2020-10-01 00:00:00

  • BCG treatment of existing Ta, T1 tumours or carcinoma in situ of the bladder.

    abstract::There are theoretical limits to the efficacy of intravesical instillation of anticancer agents as a method to prevent recurrence of superficial bladder cancer. Studies on the direct efficacy of intravesical instillation of bacillus Calmette-Guérin (BCG) to treat existing papillary tumours (Ta, T1) have shown a complet...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1159/000475202

    authors: Akaza H

    更新日期:1995-01-01 00:00:00

  • Renal cell carcinoma guideline.

    abstract:OBJECTIVES:The European Association of Urology (EAU) Guideline Group for renal cell carcinoma (RCC) prepared this guideline to help urologists assess the evidence-based management of RCC and to incorporate the guideline recommendations into their clinical practice. METHODS:The recommendations provided in the current g...

    journal_title:European urology

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.eururo.2007.03.035

    authors: Ljungberg B,Hanbury DC,Kuczyk MA,Merseburger AS,Mulders PF,Patard JJ,Sinescu IC,European Association of Urology Guideline Group for renal cell carcinoma.

    更新日期:2007-06-01 00:00:00

  • The early detection and diagnosis of bladder cancer: a critical review of the options.

    abstract::Bladder cancer has a high worldwide incidence matched by a tendency to recur, necessitating close and regular follow-up. Current methods of investigation of bladder cancer involve cystoscopy, ultrasound scanning and contrast urography, with additional information provided by cytology. These methods, although having a ...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1159/000052519

    authors: Saad A,Hanbury DC,McNicholas TA,Boustead GB,Woodman AC

    更新日期:2001-06-01 00:00:00

  • Efficacy, safety, and tolerability of mirabegron in patients aged ≥65yr with overactive bladder wet: a phase IV, double-blind, randomised, placebo-controlled study (PILLAR).

    abstract:BACKGROUND:The majority of patients with overactive bladder (OAB) are aged >65yr. There has been no prospectively designed study assessing treatment efficacy with the β3-adrenoreceptor agonist, mirabegron, specifically in this age group. OBJECTIVE:A phase IV study comparing flexibly dosed mirabegron versus placebo in ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2019.10.002

    authors: Wagg A,Staskin D,Engel E,Herschorn S,Kristy RM,Schermer CR

    更新日期:2020-02-01 00:00:00

  • Trigonal injection of botulinum toxin A in patients with refractory bladder pain syndrome/interstitial cystitis.

    abstract:BACKGROUND:Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease without an effective treatment, characterized by pain during bladder filling. Most nociceptive bladder afferents course in the trigone. OBJECTIVE:To evaluate efficacy and tolerability of trigonal injection of botulinum toxin A (BoNTA)...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2010.02.031

    authors: Pinto R,Lopes T,Frias B,Silva A,Silva JA,Silva CM,Cruz C,Cruz F,Dinis P

    更新日期:2010-09-01 00:00:00

  • Urachal Carcinoma Shares Genomic Alterations with Colorectal Carcinoma and May Respond to Epidermal Growth Factor Inhibition.

    abstract::Metastatic urachal carcinoma is a rare, understudied, and aggressive malignancy with limited treatment options. Histologically, urachal carcinomas resemble enteric adenocarcinomas and anecdotally respond to systemic therapies utilized in colorectal cancer. Targeted exome sequencing of archival primary tumor tissue fro...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.04.037

    authors: Collazo-Lorduy A,Castillo-Martin M,Wang L,Patel V,Iyer G,Jordan E,Al-Ahmadie H,Leonard I,Oh WK,Zhu J,McBride RB,Cordon-Cardo C,Solit DB,Sfakianos JP,Galsky MD

    更新日期:2016-11-01 00:00:00

  • EAU guidelines for the management of urinary and male genital tract infections. Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU).

    abstract::A short version of the UTI Guidelines elaborated by the Urinary Tract Infection Working Group of the Health Care Office of the European Association of Urology is presented. The topics include classification, diagnosis, treatment and follow-up of uncomplicated UTI, UTI in children, UTI in diabetes mellitus, renal insuf...

    journal_title:European urology

    pub_type: 指南,杂志文章,实务指引

    doi:10.1159/000049840

    authors: Naber KG,Bergman B,Bishop MC,Bjerklund-Johansen TE,Botto H,Lobel B,Jinenez Cruz F,Selvaggi FP,Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU).

    更新日期:2001-11-01 00:00:00

  • Genomic Predictors of Outcome in Prostate Cancer.

    abstract:CONTEXT:Given the highly variable behavior and clinical course of prostate cancer (PCa) and the multiple available treatment options, a personalized approach to oncologic risk stratification is important. Novel genetic approaches offer additional information to improve clinical decision making. OBJECTIVE:To review the...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2015.04.008

    authors: Boström PJ,Bjartell AS,Catto JW,Eggener SE,Lilja H,Loeb S,Schalken J,Schlomm T,Cooperberg MR

    更新日期:2015-12-01 00:00:00

  • Robotic-assisted laparoscopic prostatectomy: functional and pathologic outcomes with interfascial nerve preservation.

    abstract:INTRODUCTION:Robotic-assisted laparoscopic radical prostatectomy (RLRP) is increasingly becoming an alternative to open and laparoscopic radical prostatectomy in the treatment of localized prostate cancer. RLRP has been associated with low morbidity, short convalescence and comparable oncologic and functional outcomes....

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2006.10.019

    authors: Zorn KC,Gofrit ON,Orvieto MA,Mikhail AA,Zagaja GP,Shalhav AL

    更新日期:2007-03-01 00:00:00

  • Iodine-125-seed implantation combined with external radiotherapy under potentially curative intention in patients with advanced stage-C prostatic cancer.

    abstract::We report on 18 patients, aged 43-77 years, with clinical stage-C adenocarcinoma of the prostate, primarily treated by pelvic lymphadenectomy and 125I-seed implantation. After lymphadenectomy, the staging assessment differed from the preoperative diagnosis as follows: 4 patients were classified as stage C; 6 as D1, an...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472587

    authors: Frick J,Scrinzi U,Kunit G,Kogelnik HD

    更新日期:1986-01-01 00:00:00

  • Radical retropubic prostatectomy after transurethral prostatic resection.

    abstract::In 16 patients who underwent radical retropubic prostatectomy because of adenocarcinoma of the prostate after previous transurethral resection, the difficulty of the operation, the morbidity rate, and the survival time were evaluated. Eleven patients had tumours staged A2, 5 patients tumours staged B1. Duration of the...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473428

    authors: Bandhauer K,Senn E

    更新日期:1988-01-01 00:00:00

  • Ileal orthotopic bladder substitute combined with an afferent tubular segment: long-term upper urinary tract changes and voiding pattern.

    abstract:OBJECTIVE:Assessment of the long-term morbidity of the upper urinary tract and of the voiding pattern in men with an ileal orthotopic bladder substitute with an afferent tubular segment. MATERIALS AND METHODS:Men surviving more than 5 years after radical cystectomy and orthotopic bladder substitution were evaluated. T...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2004.07.009

    authors: Perimenis P,Burkhard FC,Kessler TM,Gramann T,Studer UE

    更新日期:2004-11-01 00:00:00

  • Upper tract tumours in patients with vesico-ureteral reflux and recurrent bladder tumours.

    abstract::27 patients with recurrent low-grade, low-stage transitional cell carcinoma (TCC) of the bladder and uni- or bilateral vesico-ureteral reflux were followed for up to 18 years in order to study a possible higher incidence of TCC of the upper tract. None of the patients developed tumours of the upper collecting system d...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472439

    authors: Mukamel E,Nissenkorn I,Glanz I,Vilcovsky E,Servadio C

    更新日期:1985-01-01 00:00:00

  • Adjuvant chemotherapy for invasive bladder cancer: a 2013 updated systematic review and meta-analysis of randomized trials.

    abstract:CONTEXT:The role of adjuvant chemotherapy remains poorly defined for the management of muscle-invasive bladder cancer (MIBC). The last meta-analysis evaluating adjuvant chemotherapy, conducted in 2005, had limited power to fully support its use. OBJECTIVE:To update the current evidence of the benefit of postoperative ...

    journal_title:European urology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.eururo.2013.08.033

    authors: Leow JJ,Martin-Doyle W,Rajagopal PS,Patel CG,Anderson EM,Rothman AT,Cote RJ,Urun Y,Chang SL,Choueiri TK,Bellmunt J

    更新日期:2014-07-01 00:00:00