Age, anemia, and obesity-associated oxygen desaturation during upper gastrointestinal endoscopy.

Abstract:

:Although upper gastrointestinal endoscopy is generally a safe procedure, it is known to be associated with arterial oxygen desaturation. We studied 82 patients undergoing diagnostic upper gastrointestinal endoscopy following a standard premedication consisting of xylocaine throat spray and intravenous midazolam. The mean duration of endoscopy was 8.5 +/- 0.42 min and the mean dose of midazolam was 6.3 +/- 0.15 mg. The baseline SaO2 was 94.91 +/- 0.27% and it decreased after pre-medication to 92.84 +/- 0.40% (p < 0.001) and after intubation to 91.21 +/- 0.40% (p < 0.001). A fall greater than 4% saturation occurred for 15.68% of the total endoscopy time. SaO2 < 90% was seen for 16.7% and SaO2 < 85% occurred for 2.33% total endoscopy time. In patients > 65 years old, hemoglobin < 10 g/dl, or body mass index > 28, the baseline saturation was significantly lower and a reduced SaO2 was seen throughout the procedure. We identify old age, anemia, and obesity as independent risk factors for arterial oxygen desaturation. We recommend continuous monitoring before sedation, and giving supplemental oxygen to patients with these risk factors from the outset of upper gastrointestinal endoscopy.

journal_name

Gastrointest Endosc

authors

Dhariwal A,Plevris JN,Lo NT,Finlayson ND,Heading RC,Hayes PC

doi

10.1016/s0016-5107(92)70564-1

keywords:

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

684-8

issue

6

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(92)70564-1

journal_volume

38

pub_type

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