ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy.

Abstract:

:Chronic radiation proctopathy is a common sequela of radiation therapy for malignancies in the pelvic region. A variety of medical and endoscopic therapies have been used for the management of bleeding from chronic radiation proctopathy. In this guideline, we reviewed the results of a systematic search of the literature from 1946 to 2017 to formulate clinical questions and recommendations on the role of endoscopy for bleeding from chronic radiation proctopathy. The following endoscopic modalities are discussed in our document: argon plasma coagulation, bipolar electrocoagulation, heater probe, radiofrequency ablation, and cryoablation. Most studies were small observational studies, and the evidence for effectiveness of endoscopic therapy for chronic radiation proctopathy was limited because of a lack of controlled trials and comparative studies. Despite this limitation, our systematic review found that argon plasma coagulation, bipolar electrocoagulation, heater probe, and radiofrequency ablation were effective in the treatment of rectal bleeding from chronic radiation proctopathy.

journal_name

Gastrointest Endosc

authors

Lee JK,Agrawal D,Thosani N,Al-Haddad M,Buxbaum JL,Calderwood AH,Fishman DS,Fujii-Lau LL,Jamil LH,Jue TL,Khashab MA,Law JK,Naveed M,Qumseya BJ,Sawhney MS,Storm AC,Yang J,Wani SB

doi

10.1016/j.gie.2019.04.234

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

171-182.e1

issue

2

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(19)31661-X

journal_volume

90

pub_type

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