A puerperal haemorrhagic state due to a henarin-like anticoagulant.

Abstract:

:The occurrence of a severe generalized haemorrhagic state in an obstetric case due to a heparin-like anticoagulant is described. This appeared in the post-partum period apparently following a compatible blood transfusion. The pattern of results found in conventional laboratory tests for elucidating acute blood coagulation disorders is described, and the distinction between heparinaemia and the defibrination syndrome emphasized. Protamine sulphate corrected the clotting abnormality in vitro and when administered in amounts so as to achieve a similar concentration in vivo was followed by correction of the blood coagulation and the sudden cessation of bleeding from multiple sites.

journal_name

J Clin Pathol

authors

WILLOUGHBY ML

doi

10.1136/jcp.16.2.108

keywords:

subject

Has Abstract

pub_date

1963-03-01 00:00:00

pages

108-11

eissn

0021-9746

issn

1472-4146

journal_volume

16

pub_type

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