Acute myelogenous leukemia complicated by acute necrotizing ulcerative gingivitis due to Aspergillus terreus.

Abstract:

:Infections caused by Aspergillus terreus are rare but have been associated with a poor outcome in immunocompromised patients due to frequent resistance to conventional antifungal therapy. This report describes a case of a woman who developed acute necrotizing ulcerative gingivitis (ANUG) due to A. terreus during induction chemotherapy for acute myelogenous leukemia. She initially failed to respond to treatment with amphotericin B but the infection resolved following the introduction of oral itraconazole. Opportunistic infections caused by A. terreus are an emerging problem and can be associated with a high mortality rate. Early microbiological diagnosis is critical since resistance to amphotericin B is likely and itraconazole appears to be an effective treatment for this infection.

journal_name

Leuk Lymphoma

journal_title

Leukemia & lymphoma

authors

Khoury H,Poh CF,Williams M,Lavoie JC,Nevill TJ

doi

10.1080/1042819031000060573

keywords:

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

709-13

issue

4

eissn

1042-8194

issn

1029-2403

journal_volume

44

pub_type

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