Abstract:
:How do naturally occurring polymorphisms in DNA sequence relate to variation in gene expression? Recent work to map genetic sources of expression variation has shown a surprising balance between cis and trans effects. Other work suggests some chromosomal clustering of genes by expression pattern. A synthesis of approaches may provide new insight in to adaptive mechanisms in evolution and the population basis of complex traits.
journal_name
Genome Bioljournal_title
Genome biologyauthors
Hamilton BAdoi
10.1186/gb-2002-3-10-reviews1029keywords:
subject
Has Abstractpub_date
2002-09-19 00:00:00pages
reviews1029issue
10eissn
1474-7596issn
1474-760Xjournal_volume
3pub_type
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