Abstract:
BACKGROUND:Unsedated transnasal upper endoscopy has a diagnostic yield comparable with that of sedated conventional upper endoscopy. The ability of transnasal upper endoscopy to detect Barrett's metaplasia or dysplastic change has not been systematically evaluated. The aim of this study was to assess the feasibility of transnasal upper endoscopy for surveillance of patients with Barrett's esophagus and to evaluate its histopathologic yield for Barrett's metaplasia and dysplasia. METHODS:Thirty-two patients with Barrett's esophagus were evaluated with conventional upper endoscopy and transnasal upper endoscopy. An effort was made to recruit patients known to have dysplasia. Quadrantic biopsy specimens were taken with standard (conventional upper endoscopy) and pediatric (transnasal upper endoscopy) biopsy forceps at procedures performed at least 1 week apart. Two blinded pathologists evaluated the specimens. RESULTS:Transnasal upper endoscopy detected Barrett's metaplasia histopathologically in 31 of 32 patients. Level of agreement for presence of dysplasia in biopsy specimens obtained between conventional upper endoscopy and transnasal upper endoscopy was excellent (k = 0.79). Interobserver agreement for dysplasia in specimens obtained by conventional upper endoscopy (k = 0.61) and by transnasal upper endoscopy (k = 0.61) were similar. Intraobserver agreement between conventional upper endoscopy and transnasal upper endoscopy biopsy specimens for dysplasia by pathologist 1 (k = 0.73) and pathologist 2 (k = 0.75) were also similar. No significant adverse effects were noted. CONCLUSIONS:Transnasal upper endoscopy is feasible and accurate for identification and histopathologic confirmation of Barrett's metaplasia with a histopathologic yield for dysplasia comparable with conventional upper endoscopy.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Saeian K,Staff DM,Vasilopoulos S,Townsend WF,Almagro UA,Komorowski RA,Choi H,Shaker Rdoi
10.1067/mge.2002.128131keywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
472-8issue
4eissn
0016-5107issn
1097-6779pii
S0016-5107(02)70429-Xjournal_volume
56pub_type
杂志文章abstract:BACKGROUND AND AIMS:The aim of this study was to identify the incidence of recurrent lesions after endoscopic submucosal dissection (ESD) and to determine whether scheduled endoscopic surveillance might control their development and treatment. METHODS:We reviewed the clinical data of patients who underwent gastric ESD...
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pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.08.043
更新日期:2009-04-01 00:00:00
abstract::The feasibility of infrared video imaging of subsurface vessels in the stomach was investigated both experimentally and in more detail using computer simulations of light propagation. Infrared video imaging was first attempted in several experimental situations. Images of a human arm illuminated with infrared light (w...
journal_title:Gastrointestinal endoscopy
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更新日期:1995-03-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1067/mge.2000.106310
更新日期:2000-06-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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更新日期:1997-09-01 00:00:00
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更新日期:2001-07-01 00:00:00
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pub_type: 临床试验,杂志文章
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abstract:BACKGROUND:Percutaneous endoscopic gastrostomy (PEG) is an accepted method of placing a feeding tube to enable enteral feeding in patients with swallowing difficulties. However, the factors associated with complications and death after PEG have not been studied in detail. We describe the largest audit of deaths after P...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2007.10.019
更新日期:2008-08-01 00:00:00
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更新日期:2012-06-01 00:00:00
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更新日期:2017-05-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-08-01 00:00:00
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更新日期:2020-09-01 00:00:00
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更新日期:2012-08-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(04)01712-2
更新日期:2004-09-01 00:00:00
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doi:10.1016/j.gie.2013.02.006
更新日期:2013-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.gie.2006.04.031
更新日期:2006-10-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.gie.2009.01.024
更新日期:2009-09-01 00:00:00
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更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:MRCP and EUS have replaced ERCP in the diagnosis of biliary diseases, but the latter is needed for treatment. This study evaluates a new approach in the management of common bile duct stones, by using an oblique-viewing echoendoscope. METHODS:Nineteen patients with acute abdominal pain associated with incre...
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pub_type: 临床试验,杂志文章
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更新日期:2002-04-01 00:00:00
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更新日期:2014-05-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2010-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.gie.2005.04.053
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Previous studies have validated EUS-guided needle-based confocal laser endomicroscopy (nCLE) diagnosis of intraductal papillary mucinous neoplasms (IPMNs). We sought to derive EUS-guided nCLE criteria for differentiating IPMNs with high-grade dysplasia/adenocarcinoma (HGD-Ca) from those with low/int...
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pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The quality of life (QOL) of patients who survive early gastric cancer (EGC) is an area of increasing interest. OBJECTIVE:To compare the QOL and degree of worry of cancer recurrence in EGC patients who underwent endoscopic submucosal dissection (ESD) or surgery. DESIGN:Cross-sectional study. SETTINGS:A te...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2003-11-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
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更新日期:2001-01-01 00:00:00