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Correlation between acid-base status, concentrations of lactate and of pyruvate in blood and cerebrospinal fluid in patients treated in an intensive care unit.

Abstract：

:Results of examinations of 41 patients treated in an intensive care unit are reported. The patients were divided into three groups and examined on the first and twelfth days of treatment. In the first group were 15 patients who had received circulatory resuscitation, the second group was 13 patients with lesions of the central nervous system of traumatic or vascular origin and the third group was 13 patients with acute respiratory insufficiency of toxic or infective origin. The cerebrospinal fluid of patients in the second group showed the lowest pH (mean pH 7.28) and bicarbonate concentration (19.05 mequiv./1); this group also had the lowest PO2 values. Moderate respiratory alkalosis was observed in the arterial blood of patients with lesions of the central nervous system. Concentrations of lactate in the cerebrospinal fluid were increased in all three groups of patients although blood lactate concentrations were normal. The lactate/pyruvate concentration ratio was highest in the resuscitated patients.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Wołowicka L,Drobnik L,Tomaszkiewicz T

doi

10.1016/0300-9572(75)90062-3

keywords:

subject

Has Abstract

pub_date

1975-01-01 00:00:00

pages

33-8

issue

1

eissn

0300-9572

issn

1873-1570

pii

0300-9572(75)90062-3

journal_volume

4

pub_type

杂志文章

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