Inhibition of rac1 reduces PDGF-induced reactive oxygen species and proliferation in vascular smooth muscle cells.

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) recurrence and development of de novo malignancy (DNM) after liver transplantation (LT) are the major causes of late recipient death. METHODS:We analyzed the incidence of extrahepatic DNM following living donor LT according to the status of pretransplant hepatic malignancy. We...

journal_title：Journal of Korean medical science

authors： Park GC,Hwang S,Ahn CS,Kim KH,Moon DB,Ha TY,Song GW,Jung DH,Yoon YI,Cho HD,Kwon JH,Chung YK,Kang SH,Choi JU,Jung IJ,Lee SG

更新日期：2020-03-23 00:00:00

abstract：:A 17-yr-old young woman was referred to our hospital with a 2-yr history of claudication of the lower extremities and severe arterial hypertension. Physical examination revealed significantly different blood pressures between both arms (160/92 and 180/95 mmHg) and legs (92/61 and 82/57 mmHg). The hematological and bio...

journal_title：Journal of Korean medical science

authors： Shim BJ,Youn HJ,Kim YC,Kim WT,Choi YS,Lee DH,Park C,Oh YS,Chung WS,Kim JH,Choi KB,Hong SJ,Jung SE,Hahn ST

更新日期：2008-06-01 00:00:00

abstract：:This study was performed to investigate differences between children who did and did not experience peer rejection in psychological state through surveys and in emotion processing during an interpersonal stress challenge task to reflect naturalistic interpersonal face-to-face relationships. A total of 20 right-handed ...

journal_title：Journal of Korean medical science

authors： Lee HS,Lee JE,Lee KU,Kim YH

更新日期：2014-09-01 00:00:00

abstract：Background:The zoonotic disease Q fever is caused by Coxiella burnetii and usually affects high-risk human populations. We conducted a serological survey of dairy cattle farmers in Korea to determine seroreactivity and identify risk factors for C. burnetii infection. Methods:This cross-sectional study included 1,824 o...

journal_title：Journal of Korean medical science

authors： Park JH,Chu H,Yoo SJ,Hwang KJ,Lim HS

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:Meniscus surgeries are frequently performed in orthopaedics. However, their current status is not well known in many countries, including Korea. This study aimed to investigate the national trends of meniscus surgery in Korea. METHODS:Information from the national database was acquired through the Korean He...

journal_title：Journal of Korean medical science

authors： Chung KS,Ha JK,Kim YS,Kim JH,Ra HJ,Kong DH,Wang PW,Choi CH,Kim JG

更新日期：2019-08-19 00:00:00

abstract：:This observational study aimed at evaluating recent superwarfarin intoxication of Korean patients. Ten patients were diagnosed as or highly suspicious for superwarfarin intoxication. Case report forms described by attending hematologists of the patients were collected and analyzed. Bleeding symptoms were varied among ...

journal_title：Journal of Korean medical science

authors： Hong J,Yhim HY,Bang SM,Bae SH,Yuh YJ,Yoon SS,Yoon HJ,Kim ST,Chi HS

更新日期：2010-12-01 00:00:00

abstract：:Adenovirus (AdV) can cause severe pneumonia in non-immunocompromised host, but limited data exist on the distinctive characteristics of AdV pneumonia in non-immunocompromised patients. We evaluated distinctive clinico-laboratory and radiological characteristics and outcomes of AdV pneumonia (n = 179), compared with no...

journal_title：Journal of Korean medical science

authors： Yoon H,Jhun BW,Kim H,Yoo H,Park SB

更新日期：2017-02-01 00:00:00

abstract：:Blood-borne metastatic involvement of the stomach by cancer is a rare entity. According to the number of reports in the literature, the most common tumors that spread to the stomach through the blood stream are malignant melanoma, breast carcinoma and lung carcinoma. Recently, two cases of metastatic involvement of th...

journal_title：Journal of Korean medical science

authors： Kim HS,Jang WI,Hong HS,Lee CI,Lee DK,Yong SJ,Shin KC,Shim YH

更新日期：1993-02-01 00:00:00

abstract：:The increasing interest in healthcare and health screening events is revealing additional cases of asymptomatic isolated microscopic hematuria (IMH). However, a consensus of the evaluation and explanation of the IMH prognosis is controversial among physicians. Here, we present the natural course of IMH together with t...

journal_title：Journal of Korean medical science

authors： Lee HM,Hyun JI,Min JW,Lee K,Kim YK,Choi EJ,Song HC

更新日期：2016-06-01 00:00:00

abstract：:A prospective multicenter observational study was performed to investigate the epidemiology and outcomes of community-acquired severe sepsis and septic shock. Subjects included 1,192 adult patients admitted to the 22 participating intensive care units (ICUs) of 12 university hospitals in the Korean Sepsis Registry Sys...

journal_title：Journal of Korean medical science

authors： Park DW,Chun BC,Kim JM,Sohn JW,Peck KR,Kim YS,Choi YH,Choi JY,Kim SI,Eom JS,Kim HY,Song JY,Song YG,Choi HJ,Kim MJ

更新日期：2012-11-01 00:00:00

abstract：:Thirty-six cases of necrotizing lymphadenitis--including 33 cases of unknown etiology, 1 typhoid lymphadenopathy, and 2 cases of suspicious lupus lymphadenopathy--were clinico-pathologically reviewed and analyzed with immunostaining for s-100 and lysozyme. All cases histologically showed architectural effacement by pa...

journal_title：Journal of Korean medical science

authors： Cho KJ,Kim CW,Park SH,Lee SK

更新日期：1991-03-01 00:00:00

abstract：:To compare the mediator releasability between atopic and nonatopic asthmatics, we measured basophil histamine releasability (BaHR) using a calcium-ionophore A23187 and anti-IgE in 137 subjects who were treated at Seoul National University Hospital. Subjects were categorized into atopic (group AA, n=77) or nonatopic as...

journal_title：Journal of Korean medical science

authors： Son JW,Kim YK,Chung JW,Lee SR,Cho SH,Min KU,Koh YY,Kim YY

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that the impact of social factors on harmful alcohol use between men and women may be different. We aimed to explore the gender-based difference in temporal trend and social risk factors associated with harmful alcohol use. METHODS:The Korea National Health and Nutrition Examination...

journal_title：Journal of Korean medical science

authors： Choe SA,Yoo S,JeKarl J,Kim KK

更新日期：2018-01-22 00:00:00

abstract：:Emergency surgical repair for acute traumatic aortic ruptures has been associated with a high peri-procedural mortality rate. Endovascular stent-grafting, as a less invasive procedure, has shown encouraging results. This report describes a patient with a short landing zone, who was treated by transposing the supra-aor...

journal_title：Journal of Korean medical science

authors： Ryu YG,Choo SJ,Lim JY,Yoon HK,Chung CH

更新日期：2010-01-01 00:00:00

abstract：:The time between symptom onset and arrival at an emergency department (ED) (S2D) is a crucial time for optimal intravenous reperfusion care for ischemic stroke. We aimed to analyze the effect of emergency medical services (EMS) utilization and inter-hospital transfer on S2D in Korea. Ischemic stroke patients were pros...

journal_title：Journal of Korean medical science

authors： Park HA,Ahn KO,Shin SD,Cha WC,Ro YS

更新日期：2016-01-01 00:00:00

abstract：:Previous exposure to antimicrobials is a major risk factor for Clostridioides difficile infection (CDI). Antibiotic prescription and C. difficile toxin assay records of patients admitted to a tertiary hospital in Korea from 2009 to 2013 were collected to investigate the association between antibiotic consumption and C...

journal_title：Journal of Korean medical science

authors： Kim B,Kim J,Pai H

更新日期：2020-12-07 00:00:00

abstract：:Cowden's disease, or multiple hamartoma syndrome, is an uncommon condition with characteristic mucocutaneous lesions associated with abnormalities of the breast, thyroid, and gastrointestinal tract. We describe a 32-year-old man with oral mucosal papillomatosis and plantar hyperkeratosis as a definite case of Cowden's...

journal_title：Journal of Korean medical science

authors： Lee HR,Moon YS,Yeom CH,Kim KW,Chun JY,Kim HK,Choi HS,Kim DK,Chung TS

更新日期：1997-12-01 00:00:00

abstract：:Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases the level of inflammation biomarkers and the GSTM1 and GSTP1 gene polymorphisms are associated with inflammatory ...

journal_title：Journal of Korean medical science

authors： Kim JH,Park SG,Lee KH,Choi JH,Ha EH,Myung SK,Hong YC

更新日期：2006-12-01 00:00:00

abstract：:The selective cyclooxygenase-2 (COX-2) and 5-lipoxygenase (LOX) inhibitors might inhibit prostaglandin synthesis and reduce proteinuria. The present study was designed to investigate the anti-proteinuric effects of nordihydroguaiaretic acid (NDGA) as compared with celecoxib in puromycin aminonucleoside (PAN) nephrosis...

journal_title：Journal of Korean medical science

authors： Lee DW,Kwak IS,Lee SB,Song SH,Seong EY,Chung HC,Yang BY,Lee MY,Sol MY

更新日期：2009-01-01 00:00:00

abstract：:The overexpression of X-linked inhibitor of apoptosis protein (XIAP), a member of IAP family protein, is intuitively expected to be associated with unfavorable clinical features in malignancies; however, there have been only a very limited number of studies reporting the clinical relevance of XIAP expression. This stu...

journal_title：Journal of Korean medical science

authors： Sung KW,Choi J,Hwang YK,Lee SJ,Kim HJ,Kim JY,Cho EJ,Yoo KH,Koo HH

更新日期：2009-08-01 00:00:00

abstract：:This study examined the normal ranges and the determinants for various parameters of the short-term heart rate variability (HRV) measurements in a large Korean sample of healthy people. HRV measurements were obtained in 2,748 healthy men and 735 healthy women 18-65 yr of age. The mean total power (TP), low frequency (...

journal_title：Journal of Korean medical science

authors： Kim GM,Woo JM

更新日期：2011-10-01 00:00:00

abstract：:IMR is useful for assessing the microvascular dysfunction after primary percutaneous coronary intervention (PCI). It remains unknown whether index of microcirculatory resistance (IMR) reflects the functional outcome in patients with anterior myocardial infarction (AMI) with or without microvascular obstruction (MO).Th...

journal_title：Journal of Korean medical science

authors： Yoo SH,Yoo TK,Lim HS,Kim MY,Koh JH

更新日期：2012-09-01 00:00:00

abstract：:Clinical studies can be conducted to gather real world evidence (RWE) not available from randomized controlled trials, providing new information and knowledge. Although the concept of RWE emerged relatively recently, numerous clinical studies are utilizing it. However, many researchers are engaging in trial and error ...

journal_title：Journal of Korean medical science

authors： Kim HS,Kim JH

更新日期：2019-01-16 00:00:00

abstract：:Pulmonary arteriovenous malformations (PAVMs) are thin-walled aneurysms caused by abnormal communication between the pulmonary arteries and veins. Migraine headaches are sometimes the presenting clinical manifestation of PAVMs. Although embolotherapy, using detachable balloons or stainless steel coils, is generally ac...

journal_title：Journal of Korean medical science

authors： Na SJ,Cho HM,Park JS

更新日期：2009-04-01 00:00:00

abstract：:The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a TNF beta gene polymorphism is associated with autoimmune thyroiditis, we analyzed the TNF beta gene polymo...

journal_title：Journal of Korean medical science

authors： Chung JH,Cho BY,Lee HK,Kim TG,Han H,Koh CS

更新日期：1994-04-01 00:00:00

abstract：:There have been many epidemiological researches of chronic kidney disease (CKD), accompanied by an increase in the incidence of coronary heart disease (CHD). However, as far as we know, little research has been done to examine the extent of the relationship between CKD and CHD as estimated by Framingham risk score (FR...

journal_title：Journal of Korean medical science

authors： Ryoo JH,Kim SG,Suh BS,Kim DI,Park SK

更新日期：2011-06-01 00:00:00

abstract：:We compared the clinical efficacy of a short-term intervention of 308-nm excimer laser with that of narrow-band UVB (NBUVB) phototherapy for vitiligo patients to see the early response. Twenty-three symmetrically patterned patches of vitiligo on 8 patients were selected. Vitiligo patches on one side of the body were t...

journal_title：Journal of Korean medical science

authors： Hong SB,Park HH,Lee MH

更新日期：2005-04-01 00:00:00

abstract：:Concentrations of heavy metals exceed safety thresholds in the soil near Janghang Copper Refinery, a smelter in Korea that operated from 1936 to 1989. This study was conducted to evaluate the level of exposure to toxic metals and the potential effect on health in people living near the smelter. The study included 572 ...

journal_title：Journal of Korean medical science

authors： Kim YD,Eom SY,Yim DH,Kim IS,Won HK,Park CH,Kim GB,Yu SD,Choi BS,Park JD,Kim H

更新日期：2016-04-01 00:00:00

abstract：:This prospective study aimed to evaluate the satisfaction of patients who participated in the decision-making process for selecting an anesthesia method for surgery; the patients' preferred role (active, collaborative or passive) in the decision-making; and the patients' preferred choice of anesthetic method. The stud...

journal_title：Journal of Korean medical science

authors： Hwang SM,Lee JJ,Jang JS,Gim GH,Kim MC,Lim SY

更新日期：2014-02-01 00:00:00

abstract：:We evaluated the clinical course of subchondral insufficiency fracture of the femoral head (SIFFH) and its characteristic findings with special regard to joint space narrowing (JSN). Thirty-one cases of SIFFH of mean age 68.9 yr initially underwent limited weight-bearing conservative treatment. During the follow-up pe...

journal_title：Journal of Korean medical science

authors： Yoon PW,Kwak HS,Yoo JJ,Yoon KS,Kim HJ

更新日期：2014-04-01 00:00:00