Abstract:
:We compared the clinical efficacy of a short-term intervention of 308-nm excimer laser with that of narrow-band UVB (NBUVB) phototherapy for vitiligo patients to see the early response. Twenty-three symmetrically patterned patches of vitiligo on 8 patients were selected. Vitiligo patches on one side of the body were treated 2 times per week for a maximum of 20 treatments with the excimer laser, and NBUVB phototherapy was used on patches on the other side. Improvement (repigmentation) was assessed on a visual scale via serial photographs taken every five treatments and scored as follows: 0,< or =1% improvement; 1,< or =25% improvement; 2, 26-50% improvement; 3, 51-75% improvement; and 4, > or =75% improvement. At five treatments, the excimer laser-treated patches had an average score of 0.26, compared with 0.04 for patches treated with NBUVB phototherapy. A slightly higher repigmentation (p>0.05) in the excimer treated area was thus observed. At 10, 15, or 20 treatments, the differences between the average scores were significant: 0.83, 1.17, and 1.39 for the excimer-treated patches, and 0.17, 0.30, and 0.74 for the NBUVB phototherapy-treated areas (p<0.05). In conclusion, the 308-nm excimer laser appears to be more effective than NBUVB phototherapy, as it produces more rapid and profound repigmentation.
journal_name
J Korean Med Scijournal_title
Journal of Korean medical scienceauthors
Hong SB,Park HH,Lee MHdoi
10.3346/jkms.2005.20.2.273keywords:
subject
Has Abstractpub_date
2005-04-01 00:00:00pages
273-8issue
2eissn
1011-8934issn
1598-6357pii
200504273journal_volume
20pub_type
杂志文章abstract::The prognostic significance of multidrug resistance (MDR) gene expression is controversial. We investigated whether multidrug resistance gene 1 (MDR1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) mRNA expression are associated with outcomes in acute leukemia patients. At diagnosis we e...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2006.21.2.253
更新日期:2006-04-01 00:00:00
abstract::The safety of accelerated schedules of allergen immunotherapy (ASAI) in patients with bronchial asthma (BA) has been reported but there are little data on the safety of ASAI for patients with atopic dermatitis (AD). In this study, we investigated the safety of ASAI in patients with AD. Sixty patients with AD and 18 pa...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2011.26.9.1159
更新日期:2011-09-01 00:00:00
abstract::Despite the increasing use of the rectal balloon in prostate cancer radiotherapy, many issues still remain to be verified objectively including its positional reproducibility and relevance to treatment morbidity. We have developed a custom rectal balloon that has a scale indicating the depth of insertion and dilates s...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2009.24.5.894
更新日期:2009-10-01 00:00:00
abstract::Malnutrition and inflammation are related to high rates of morbidity and mortality in hemodialysis patients. Resistin is associated with nutrition and inflammation. We attempted to determine whether resistin levels may predict clinical outcomes in hemodialysis patients. We conducted a prospective evaluation of 100 out...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2012.27.4.377
更新日期:2012-04-01 00:00:00
abstract::Most of malignant tumors arising in ovarian and extraovarian endometriosis are carcinomas. Mixed mullerian tumor and endometrial stromal sarcoma arising in intestinal endometriosis are rarely described, but its clinicopathologic features have not been well characterized. Here we report a case of endometrial stromal sa...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,评审
doi:10.3346/jkms.2002.17.3.412
更新日期:2002-06-01 00:00:00
abstract::This research aimed to investigate the changes in ethical issues in everyday clinical practice recognized by critical care nurses during two observation periods. We conducted a retrospective analysis of data obtained by prospective questionnaire surveys of nurses in the intensive care units (ICU) of a tertiary univers...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2015.30.4.495
更新日期:2015-04-01 00:00:00
abstract::The pathogenesis of chronic cyclosporine A (CsA) nephrotoxicity has not been elucidated, but apoptosis is thought to play an important role in CsA induced tubular atrophy. Recently Fas-Fas ligand system mediated apoptosis has been frequently reported in many epithelial cells as well as in T lymphocytes. We investigate...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2001.16.5.603
更新日期:2001-10-01 00:00:00
abstract::A 25-yr-old woman presented with a right pleural effusion. Destruction of 9th through 12th ribs, adjacent vertebral bodies, and transverse processes was noted on plain radiograph and a large low-attenuated, irregular shaped mass lesion with peripheral rim enhancement, destroying vertebral body and transverse process, ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2002.17.6.826
更新日期:2002-12-01 00:00:00
abstract::Congenital insensitivity to pain with anhidrosis (CIPA) is a very rare genetic disorder of the peripheral nervous system characterized by recurrent episodes of unexplained fever, generalized anhidrosis, insensitivity to pain and temperature, and accompanied by self-mutilating behavior and mental retardation. We report...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1999.14.4.460
更新日期:1999-08-01 00:00:00
abstract::The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) has become of great concern in both hospital and community settings. To evaluate the prevalence and risk factors for methicillin resistance among Staphylococcus aureus, blood isolates in our Emergency Department (ED) were collected. All pa...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2007.22.4.682
更新日期:2007-08-01 00:00:00
abstract::We evaluated the prevalence and risk factors for early age-related macular degeneration (AMD) in Koreans 50 yr of age or older who were examined at a single health promotion center. We retrospectively reviewed the records of 10,449 subjects who visited the center over a 6-month period. Fundus photography was performed...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2012.27.5.537
更新日期:2012-05-01 00:00:00
abstract::Cardiac autonomic neuropathy (CAN) is a common and most neglected complication of diabetes, estimated to be roughly 8% in recently diagnosed patients and greater than 50% in patients with chronic disease history. The insulin resistance (IR) itself is bidirectionally associated with increased risk of type 2 diabetes me...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2017.32.7.1131
更新日期:2017-07-01 00:00:00
abstract::Using the methods of restriction fragment length polymorphism (RFLP) and single strand conformation polymorphism (SSCP) analyses, we have examined 33 cases of human gliomas with various malignant grades to detect the deletions of putative tumor suppressor gene loci, chromosome 10, 13q(retinoblastoma gene, Rb), 17p, an...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1995.10.6.442
更新日期:1995-12-01 00:00:00
abstract::A retrospective study was conducted to determine the mortality, causes and risk factors for death among HIV-infected patients receiving antiretroviral therapy (ART) in Korea. The outcomes were determined by time periods, during the first year of ART and during 1-5 yr after ART initiation, respectively. Patients lost t...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2013.28.7.990
更新日期:2013-07-01 00:00:00
abstract::Serotypings have been used as markers for epidemiological surveys of Streptococcus pyogenes infections. Seventy-seven strains of S. pyogenes isolated from the throats of elementary school children in Kangwon Province in Korea in March and April 1992 were serotyped with M and/or opacity factor (OF) antisera. Sixty-eigh...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1996.11.2.133
更新日期:1996-04-01 00:00:00
abstract::This research focuses on the analysis regarding disclosure of financial conflicts of interest (FCOI) after Gelsinger v. University of Pennsylvania (Penn). The main legal issue was that the participants did not have enough opportunity to make an autonomous decision about participating in the research because he was not...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,评审
doi:10.3346/jkms.2017.32.12.1910
更新日期:2017-12-01 00:00:00
abstract::We conducted this study to investigate the synergistic effect of human urine-derived stem cells (USCs) and surface modified composite scaffold for bladder reconstruction in a rat model. The composite scaffold (Polycaprolactone/Pluronic F127/3 wt% bladder submucosa matrix) was fabricated using an immersion precipitatio...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2015.30.12.1754
更新日期:2015-12-01 00:00:00
abstract:Background:Alendronate (AL), a drug for inhibiting osteoclast-mediated bone-resorption, was intercalated into an inorganic drug delivery nanovehicle, layered double hydroxide (LDH), to form a new nanohybrid, AL-LDH, with 1:1 heterostructure along the crystallographic C-axis. Based on the intercalation reaction strategy...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2019.34.e37
更新日期:2019-01-25 00:00:00
abstract:BACKGROUND:This study described and analysed the features of powered mobility device (PMD)-related injuries and compared elderly and younger adult injuries. METHODS:Data from Korea Emergency Department-based Injury In-depth Surveillance (EDIIS) database involving eight emergency departments in 2011-2016 were analysed....
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2020.35.e60
更新日期:2020-03-09 00:00:00
abstract::We investigated the incidence of unsuspected gallbladder (GB) carcinomas in a total of 527 consecutive GB specimens resected for benign biliary disease and their clinicopathological features. The GBs were examined microscopically using stepwise tissue sections at 5 mm interval. Clinical and pathological findings were ...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.1997.12.6.519
更新日期:1997-12-01 00:00:00
abstract::We aimed to investigate epidemiology and host- and pathogen-related factors associated with clinical severity of acute gastroenteritis (AGE) in children after rotavirus vaccination introduction. Factors assessed included age, co-infection with more than 2 viruses, and virus-toxigenic Clostridium difficile co-detection...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2017.32.3.465
更新日期:2017-03-01 00:00:00
abstract::Size selection of the laryngeal mask airway (LMA) Classic based on actual body weight remains a common practice. However, ideal body weight might allow for a better size selection in obese patients. The purpose of our study was to compare the utility of ideal body weight and actual body weight when choosing the approp...
journal_title:Journal of Korean medical science
pub_type: 杂志文章,随机对照试验
doi:10.3346/jkms.2015.30.8.1197
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) recurrence and development of de novo malignancy (DNM) after liver transplantation (LT) are the major causes of late recipient death. METHODS:We analyzed the incidence of extrahepatic DNM following living donor LT according to the status of pretransplant hepatic malignancy. We...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2020.35.e69
更新日期:2020-03-23 00:00:00
abstract::It has been suggested that there is an association between environmental, low-level arsenic exposure and the risk of diabetes mellitus (DM), but little research has been conducted. Here, the glucose tolerance status and urinary creatinine adjusted total arsenic concentrations were analyzed in 3,602 subjects ≥ 20 yr of...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2013.28.6.861
更新日期:2013-06-01 00:00:00
abstract::Default from tuberculosis (TB) treatment could exacerbate the disease and result in the emergence of drug resistance. This study identified the risk factors for default from TB treatment in Korea. This single-center case-control study analyzed 46 default cases and 100 controls. Default was defined as interrupting trea...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2016.31.2.254
更新日期:2016-02-01 00:00:00
abstract::This study was performed to determine the incidence and serogroups of meningococcal disease in the Korean Army. From August 2000 to July 2001, we identified prospective cases in the Korean Army. Meningococcal disease was confirmed by isolation of Neisseria meningitidis or detection of its antigen by latex agglutinatio...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2003.18.2.163
更新日期:2003-04-01 00:00:00
abstract::The incidence of specific intracranial parenchymal lesions of HIV-infected patients varies considerably between countries. In the Republic of Korea, the number of HIV-infected patients is increasing, but little is known regarding the spectrum of intracranial parenchymal lesions in these patients. The aim of the presen...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2010.25.7.1005
更新日期:2010-07-01 00:00:00
abstract::Antidotes for toxicological emergencies can be life-saving. However, there is no nationwide estimation of the antidotes stocking amount in Korea. This study tried to estimate the quantities of stocking antidotes at emergency department (ED). An expert panel of clinical toxicologists made a list of 18 emergency antidot...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2014.29.11.1562
更新日期:2014-11-01 00:00:00
abstract::The time between symptom onset and arrival at an emergency department (ED) (S2D) is a crucial time for optimal intravenous reperfusion care for ischemic stroke. We aimed to analyze the effect of emergency medical services (EMS) utilization and inter-hospital transfer on S2D in Korea. Ischemic stroke patients were pros...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2016.31.1.139
更新日期:2016-01-01 00:00:00
abstract::Cutaneous nocardiosis, which usually manifests in the form of pustules, abscesses, or subcutaneous nodules, is occasionally found in immunocompromised patients. A 59-yr-old Korean man with myasthenia gravis and thymoma developed nodular skin lesions on his trunk. Histopathologically, abscess formation with a dense inf...
journal_title:Journal of Korean medical science
pub_type: 杂志文章
doi:10.3346/jkms.2002.17.2.279
更新日期:2002-04-01 00:00:00