Anti-CD20 antibody (rituximab) administration in patients with late occurring lymphomas after solid organ transplant.

abstract：:A new method, combining seminested polymerase chain reaction (PCR) with heteroduplex analysis, was utilized to detect follicular lymphoma (FL) cells in peripheral blood. The method, based on the detection of IgH rearrangements in DNA, detected the presence of monoclonal B cells in FL patients with a high frequency. ...

journal_title：Haematologica

authors： Oehadian A,Koide N,Mu MM,Hassan F,Yoshida T,Yokochi T

更新日期：2005-02-01 00:00:00

abstract：:The present study reports a method for the easy, rapid and cost effective detection of heterozygous large deletions. As a model gene all exons of the antithrombin gene were amplified in a one tube multiplex polymerase chain reaction (PCR) and the products separated according to their size by reverse-phase ion-pair hig...

journal_title：Haematologica

authors： Pavlova A,El-Maarri O,Luxembourg B,Lindhoff-Last E,Kochhan L,Bruhn HD,Delev D,Watzka M,Seifried E,Oldenburg J

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To compare the clinical results of two consecutive therapeutic protocols including autologous blood stem cell transplantation (ABSCT) for patients with de novo acute myeloblastic leukemia (AML) in first complete remission (CR1). DESIGN AND METHODS:Between November 1989 and January 1997, 50 pat...

journal_title：Haematologica

authors： de la Rubia J,Sanz GF,Martín G,Martínez J,Cervera J,Solves P,Jiménez C,Arnao M,Vicente A,Jarque I,Sempere A,Sanz MA

更新日期：1999-02-01 00:00:00

abstract：:n patients with Kasabach-Merritt syndrome (KMS), local activation of coagulation commonly results in disseminated intravascular coagulation (DIC). Progress of DIC is associated with 30-40% mortality as a result of uncontrollable hemorrhage. A 39-year-old woman with an enlarging giant liver hemangioma was diagnosed as ...

journal_title：Haematologica

authors： Ontachi Y,Asakura H,Omote M,Yoshida T,Matsui O,Nakao S

更新日期：2005-11-01 00:00:00

abstract：:In a case of acute myeloid leukemia we report molecular cytogenetic findings of a t(3;11)(q12;p15), characterized as a new NUP98 translocation rearranging with LOC348801 at chromosome 3. NUP98 involvement was detected by fluorescence in situ hybridization. 3'-RACE-PCR showed nucleotide 1718 (exon 13) of NUP98 was fuse...

journal_title：Haematologica

authors： Gorello P,Brandimarte L,La Starza R,Pierini V,Bury L,Rosati R,Martelli MF,Vandenberghe P,Wlodarska I,Mecucci C

更新日期：2008-09-01 00:00:00

abstract：:Recent advances in unrelated cord blood transplantation have increased chances and options available in allogeneic stem cell transplantation. The effect of HLA disparity on outcomes after cord blood transplantation was studied recently in mainly pediatric populations. Results showed that HLA matching in combination wi...

journal_title：Haematologica

authors： Atsuta Y,Kanda J,Takanashi M,Morishima Y,Taniguchi S,Takahashi S,Ogawa H,Ohashi K,Ohno Y,Onishi Y,Aotsuka N,Nagamura-Inoue T,Kato K,Kanda Y,HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation.

更新日期：2013-05-01 00:00:00

abstract：:This review deals with the chronic lymphoproliferative disease of large granular lymphocytes endowed with T and natural killer cell characteristics. The disease is sufficiently characterized to allow its distinction from other lymphoproliferative disorders of the T cell type. The heterogeneous clinical course and labo...

journal_title：Haematologica

authors： Bassan R,Rambaldi A,Barbui T

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A progressively growing number of peripheral blood stem cell transplants (PBSCTs) are being performed in patients with newly diagnosed multiple myeloma (MM) since they are ever more frequently being offered as up-front therapy. Furthermore, there are considerable concerns regarding the appropr...

journal_title：Haematologica

authors： Morabito F,Martino M,Stelitano C,Oliva E,Kropp M,Irrera G,Console G,Fujo M,Messina G,Molica S,Callea V,Iacopino P

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Increased levels of microparticles exposing tissue factor circulate in the blood of patients with coronary heart disease, possibly disseminating their pro-thrombotic and pro-inflammatory potential. Because diets rich in n-3 (polyunsaturated) fatty acids have been associated with reduced incidence of coronary...

journal_title：Haematologica

authors： Del Turco S,Basta G,Lazzerini G,Evangelista M,Rainaldi G,Tanganelli P,Christensen JH,Schmidt EB,De Caterina R

更新日期：2008-06-01 00:00:00

abstract：:New drugs are needed for the treatment of relapsed acute lymphoblastic leukemia and preclinical evaluation of the MEK inhibitor, selumetinib, has shown that this drug has excellent activity in those leukemias with RAS pathway mutations. The proapoptotic protein, BIM is pivotal in the induction of cell death by both se...

journal_title：Haematologica

authors： Matheson EC,Thomas H,Case M,Blair H,Jackson RK,Masic D,Veal G,Halsey C,Newell DR,Vormoor J,Irving JAE

更新日期：2019-09-01 00:00:00

abstract：:The risk of developing premature ovarian failure and azoospermia is a major concern in long-term survivors treated for Hodgkin's lymphoma. Alkylating chemotherapy containing procarbazine and/or cyclophosphamide causes prolonged azoospermia in 90-100% of men and premature ovarian failure in 5-25% of women under the age...

journal_title：Haematologica

authors： Harel S,Fermé C,Poirot C

更新日期：2011-11-01 00:00:00

abstract：:Juvenile myelomonocytic leukemia is a rare myeloproliferative neoplasm characterized by hyperactive RAS signaling. Neurofibromin1 (encoded by the NF1 gene) is a negative regulator of RAS activation. Patients with neurofibromatosis type 1 harbor loss-of-function mutations in NF1 and have a 200- to 500-fold increased ri...

journal_title：Haematologica

authors： Sachs Z,Been RA,DeCoursin KJ,Nguyen HT,Mohd Hassan NA,Noble-Orcutt KE,Eckfeldt CE,Pomeroy EJ,Diaz-Flores E,Geurts JL,Diers MD,Hasz DE,Morgan KJ,MacMillan ML,Shannon KM,Largaespada DA,Wiesner SM

更新日期：2016-10-01 00:00:00

abstract：:Hematologic responses to hypomethylating agents are often delayed in patients with myelodysplastic syndrome or acute myeloid leukemia. Fetal hemoglobin is a potential novel bio-marker of response: recently, we demonstrated that a high fetal hemoglobin level prior to decitabine treatment was associated with superior ou...

journal_title：Haematologica

authors： Stomper J,Ihorst G,Suciu S,Sander PN,Becker H,Wijermans PW,Plass C,Weichenhan D,Bissé E,Claus R,Lübbert M

更新日期：2019-01-01 00:00:00

abstract：:Left ventricular (LV) failure is the main cause of death in thalassemia. Iron overload in patients with thalassemia leads to the formation of oxygen free radicals. Of the various apolipoprotein E (apoE) alleles, apoE4 is the least efficient in conditions of oxidative stress in comparison with apoE2 and apoE3. Our resu...

journal_title：Haematologica

authors： Bazrgar M,Karimi M,Peiravian F,Fathzadeh M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Granulocyte colony-stimulating factor mobilized peripheral blood stem cells are increasingly used instead of bone marrow as a stem cell source for transplantation. Whereas this change is almost complete for autologous transplantation, there are some concerns when considering allogeneic transplants. DESIGN A...

journal_title：Haematologica

authors： Gallardo D,de la Cámara R,Nieto JB,Espigado I,Iriondo A,Jiménez-Velasco A,Vallejo C,Martín C,Caballero D,Brunet S,Serrano D,Solano C,Ribera JM,de la Rubia J,Carreras E

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The Hong Kong government is planning to introduce an electronic smart identity card for all seven million citizens in 2003. If the smart card contains the full red cell phenotype/genotype of the individual, it may be possible to transfuse phenotype-matched blood units without pre-transfusion a...

journal_title：Haematologica

authors： Lau FY,Wong R,Chan NP,Chui CH,Ng E,Ng MH,Cheng G

更新日期：2001-07-01 00:00:00

abstract：:Autoimmune lymphoproliferative syndrome is a rare genetic disorder characterized by defective FAS-mediated apoptosis, autoimmune disease, accumulation of mature T-cell receptor alpha/beta positive, CD4 and CD8 double-negative T cells and increased risk of lymphoma. Despite frequent hematologic abnormalities, literatur...

journal_title：Haematologica

authors： Xie Y,Pittaluga S,Price S,Raffeld M,Hahn J,Jaffe ES,Rao VK,Maric I

更新日期：2017-02-01 00:00:00

abstract：:Juvenile hemochromatosis is a severe form of hereditary iron overload. It can be caused by mutations in either hepcidin or hemojuvelin genes. In this study we identified the molecular basis of juvenile hemochromatosis in three Australian families and assessed the role of potential modifying genes in individuals carryi...

journal_title：Haematologica

authors： Wallace DF,Dixon JL,Ramm GA,Anderson GJ,Powell LW,Subramaniam N

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Whether degree of iron stores influences progression of human immunodeficiency virus (HIV) disease is controversial. We studied the relationship of indirect measures of iron stores with mortality in highly active antiretroviral therapy (HAART)-naive participants from the Women's Interagency HI...

journal_title：Haematologica

authors： Gordeuk VR,Onojobi G,Schneider MF,Dawkins FW,Delapenha R,Voloshin Y,von Wyl V,Bacon M,Minkoff H,Levine A,Cohen M,Greenblatt RM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Patients with acute myeloblastic leukemia (AML) with features of myelodysplastic syndrome and abnormalities of megakaryocytopoiesis often have cytogenetic aberrations of 3q21 and 3q26 bands involving the paracentric inversion [inv(3) (q21q26)] or a reciprocal translocation [t(3;3) (q21;q26)]. ...

journal_title：Haematologica

authors： Martinelli G,Ottaviani E,Buonamici S,Isidori A,Borsaru G,Visani G,Piccaluga PP,Malagola M,Testoni N,Rondoni M,Nucifora G,Tura S,Baccarani M

更新日期：2003-11-01 00:00:00

abstract：:This study investigated the kinetics of CD3+-T cell chimerism (TCC) in 102 patients receiving reduced intensity conditioning allogeneic stem cell transplantation (RIC-allo-SCT) from an HLA-identical sibling. Patients with full donor TCC at day 30 had a higher incidence of grade 2-4 acute GVHD compared to patients in m...

journal_title：Haematologica

authors： Mohty M,Avinens O,Faucher C,Viens P,Blaise D,Eliaou JF

更新日期：2007-07-01 00:00:00

abstract：:Pseudomonas aeruginosa is one leading gram-negative organism associated with nosocomial infections. Bacteremia is life-threatening in the immunocompromised host. Increasing frequency of multi-drug-resistant (MDRPA) strains is concerning. We started a retrospective survey in the pediatric hematology oncology Italian ne...

journal_title：Haematologica

authors： Caselli D,Cesaro S,Ziino O,Zanazzo G,Manicone R,Livadiotti S,Cellini M,Frenos S,Milano GM,Cappelli B,Licciardello M,Beretta C,Aricò M,Castagnola E,Infection Study Group of the Associazione Italiana Ematologia Oncologia Pediat

更新日期：2010-09-01 00:00:00

abstract：:A probabilistic model was used to compare cryoprecipitate to viral inactivated, commercial fibrinogen concentrate to evaluate with regard to the recipient's risk of exposure to an emergent AIDS-like epidemic. In patients who occasionally need a therapeutic dose of fibrinogen, commercial fibrinogen would be marginally ...

journal_title：Haematologica

authors： Pereira A

更新日期：2007-06-01 00:00:00

abstract：:The transferability of the T2* technique for measurement of tissue iron between magnetic resonance (MR) scanners is unknown. Heart and liver multi-breath-hold T2* sequences were installed on MR scanners at six different sites. T2* was assessed locally in five or more patients with thalassemia major (n=39), and subject...

journal_title：Haematologica

authors： Tanner MA,He T,Westwood MA,Firmin DN,Pennell DJ,Thalassemia International Federation Heart T2* Investigators.

更新日期：2006-10-01 00:00:00

abstract：:Plasma levels of several soluble factors were assayed in 31 untreated patients with high-grade non-Hodgkin's lymphomas (NHL). The results showed statistically significant higher average levels of interleukin-2 (IL-2), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-2 receptor (IL-2r) and transferrin receptor (...

journal_title：Haematologica

authors： Stasi R,Conforti M,Del Poeta G,Simone MD,Coppetelli U,Tribalto M,Cantonetti M,Perrotti A,Venditti A,Papa G

更新日期：1992-11-01 00:00:00

abstract：:Renewing interest in cancer immunotherapy reflects the excellent results that have been obtained in animal models and the promising results in early clinical trails with dendritic cell (DC) based approaches. The central role that DCs play in the initiation of an immune response raises the possibility of using them to ...

journal_title：Haematologica

authors： Di Nicola M,Lemoli RM

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:A prospective study to evaluate the role of fludarabine alone or in combination with idarubicin in untreated patients with mantle cell lymphoma (MCL). DESIGN AND METHODS:Twenty-nine untreated patients with mantle cell lymphoma were stochastically treated with intravenous fludarabine at a dose ...

journal_title：Haematologica

authors： Zinzani PL,Magagnoli M,Moretti L,Battista R,Ronconi F,De Renzo A,Zaccaria A,Gentilini P,Guardigni L,Gherlinzoni F,Cellini C,Fattori PP,Bendandi M,Bocchia M,Aitini E,Tura S

更新日期：1999-11-01 00:00:00

abstract：:We previously reported initial results in 102 multiple myeloma (MM) patients treated with sequential high-dose melphalan and autologous hematopoietic cell transplantation followed by 200 cGy total body irradiation with or without fludarabine 90 mg/m2 and allogeneic hematopoietic cell transplantation. Here we present l...

journal_title：Haematologica

authors： Maffini E,Storer BE,Sandmaier BM,Bruno B,Sahebi F,Shizuru JA,Chauncey TR,Hari P,Lange T,Pulsipher MA,McSweeney PA,Holmberg L,Becker PS,Green DJ,Mielcarek M,Maloney DG,Storb R

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Diamond-Blackfan anemia is a fatal congenital anemia characterized by a specific disruption in erythroid progenitor cell development. Approximately 25% of patients have mutations in the ribosomal protein RPS19 suggesting that Diamond-Blackfan anemia may be caused by a defect in ribosome biogenesis and transl...

journal_title：Haematologica

authors： Rey MA,Duffy SP,Brown JK,Kennedy JA,Dick JE,Dror Y,Tailor CS

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Thrombosis is the major risk factor for death in patients with paroxysmal nocturnal hemoglobinuria. Previous case reports indicate that venous thrombosis in patients with paroxysmal nocturnal hemoglobinuria is amenable to thrombolysis. DESIGN AND METHODS:We reviewed the outcome of thrombolytic therapy for p...

journal_title：Haematologica

authors： Araten DJ,Notaro R,Thaler HT,Kernan N,Boulad F,Castro-Malaspina H,Small T,Scaradavou A,Magnan H,Prockop S,Chaffee S,Gonsky J,Thertulien R,Tarquini R,Luzzatto L

更新日期：2012-03-01 00:00:00