Analysis of stress- and host cell-induced expression of the Mycobacterium tuberculosis inorganic pyrophosphatase.

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:The lung of patients with cystic fibrosis (CF) is particularly sensitive to Pseudomonas aeruginosa. This bacterium plays an important role in the poor outcome of CF patients. During the disease progress, first acquisition of P. aeruginosa is the key-step in the management of CF patients. Quantitative PCR (qP...

journal_title：BMC microbiology

authors： Le Gall F,Le Berre R,Rosec S,Hardy J,Gouriou S,Boisramé-Gastrin S,Vallet S,Rault G,Payan C,Héry-Arnaud G

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Several conventional methods, including fungal culture and periodic acid-Schiff (PAS) reagent staining, have been used to diagnose oral candidiasis. The aim of this study was to evaluate the efficacy of a novel method, fungal fluorescent staining, in relation to conventional protocols in the diagnosis of ora...

journal_title：BMC microbiology

authors： Yao Y,Shi L,Zhang C,Sun H,Wu L

更新日期：2019-05-14 00:00:00

abstract：BACKGROUND:Listeria monocytogenes is the causative agent of listeriosis, a serious disease affecting both animals and humans. Here, multilocus sequence typing (MLST) was used to characterize the genetic diversity of Listeria monocytogenes strains isolated from the natural environment and animal clinical cases in Europe...

journal_title：BMC microbiology

authors： Papić B,Pate M,Félix B,Kušar D

更新日期：2019-12-18 00:00:00

abstract：BACKGROUND:The low bacterial load in samples acquired from the lungs, have made studies on the airway microbiome vulnerable to contamination from bacterial DNA introduced during sampling and laboratory processing. We have examined the impact of laboratory contamination on samples collected from the lower airways by pro...

journal_title：BMC microbiology

authors： Drengenes C,Wiker HG,Kalananthan T,Nordeide E,Eagan TML,Nielsen R

更新日期：2019-08-14 00:00:00

abstract：BACKGROUND:Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in treatment failures of bacterial infections. While this phenomenon has posed a great threat in public health, mechanisms underlying their formation in Staphylococcus aureus remain largely unknown. Increasing evi...

journal_title：BMC microbiology

authors： Sahukhal GS,Pandey S,Elasri MO

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Cryptosporidium spp. and Giardia duodenalis are important causes of diarrheal diseases in humans and animals worldwide, and there is an increased interest in the role of animals in the mechanical transmission of these protozoa. To examine the role of yaks in this process, we examined the occurrence and genot...

journal_title：BMC microbiology

authors： Qi M,Cai J,Wang R,Li J,Jian F,Huang J,Zhou H,Zhang L

更新日期：2015-05-21 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) biofilm producers represent an important etiological agent of many chronic human infections. Antibiotics and host immune responses are largely ineffective against bacteria within biofilms. Alternative actions and novel antimicrobials should be considered. In...

journal_title：BMC microbiology

authors： Dakheel KH,Rahim RA,Neela VK,Al-Obaidi JR,Hun TG,Isa MNM,Yusoff K

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:There is an urgent need to develop potent antimicrobials for the treatment of infections caused by antibiotic-resistant bacterial pathogens. Paenipeptin C' (C8-Pat) is a novel linear lipopeptide recently discovered by our group. The objectives of this study were to determine the time-kill kinetics of paenipe...

journal_title：BMC microbiology

authors： Moon SH,Huang E

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein and nonstructural protein 4B (NS4B) are potentially oncogenic. Aberrant activation of the Wnt/β-catenin signaling pathway is closely associated with hepatocarcinogenesis. We investigated the effects of HCV type 1b core protein and NS4B on Wnt/β-catenin signaling in variou...

journal_title：BMC microbiology

authors： Jiang XH,Xie YT,Cai YP,Ren J,Ma T

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:Streptococcus agalactiae (GBS) is a common pathogen to infect newborn, woman, the elderly, and immuno-compromised human and fish. 37 fish isolates and 554 human isolates of the GBS in 2007-2012 were investigated in serotypes, antibiotic susceptibility, genetic difference and pathogenicity to tilapia. RESULT...

journal_title：BMC microbiology

authors： Chu C,Huang PY,Chen HM,Wang YH,Tsai IA,Lu CC,Chen CC

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation. In this study, we used a high-throughput pyrosequencing approach to sequence the transcriptome of S. meliloti, and search for new bacterial genes missed in the previous ...

journal_title：BMC microbiology

authors： Mao C,Evans C,Jensen RV,Sobral BW

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities for causing disseminated disease in the blood of C3H/HeJ mice during early infection. RESULTS:B...

journal_title：BMC microbiology

authors： Petzke MM,Iyer R,Love AC,Spieler Z,Brooks A,Schwartz I

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:The sequenced O45:K1:H7 Escherichia coli meningitis strain S88 harbors a large virulence plasmid. To identify possible genetic determinants of pS88 virulence, we examined the transcriptomes of 88 plasmidic ORFs corresponding to known and putative virulence genes, and 35 ORFs of unknown function. RESULTS:Qua...

journal_title：BMC microbiology

authors： Lemaître C,Bidet P,Bingen E,Bonacorsi S

更新日期：2012-06-21 00:00:00

abstract：BACKGROUND:Propionibacterium acnes is a commensal of human skin but is also known to be involved in certain diseases, such as acne vulgaris and infections of orthopaedic implants. Treatment of these conditions is complicated by increased resistance to antibiotics and/or biofilm formation of P. acnes bacteria. P. acnes ...

journal_title：BMC microbiology

authors： Lood R,Mörgelin M,Holmberg A,Rasmussen M,Collin M

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. It is generally believed that the proteins encoded in these genes are important for successful survival of the organism under the hostile conditions. Analogously, t...

journal_title：BMC microbiology

authors： Yamaguchi Y,Tomoyasu T,Takaya A,Morioka M,Yamamoto T

更新日期：2003-08-12 00:00:00

abstract：BACKGROUND:Bloodstream infections represent serious conditions carrying a high mortality and morbidity rate. Rapid identification of microorganisms and prompt institution of adequate antimicrobial therapy is of utmost importance for a successful outcome. Aiming at the development of a rapid, simplified and efficient pr...

journal_title：BMC microbiology

authors： Jakovljev A,Bergh K

更新日期：2015-11-06 00:00:00

abstract：BACKGROUND:Although the most widely accepted mechanism of action for polymyxins is related to bacterial lysis via disruption, we hypothesized that this antimicrobial drug class could have other effects on Pseudomonas aeruginosa planktonic and sessile cells. Little is known regarding oxidative burst and zeta potential (...

journal_title：BMC microbiology

authors： Lima MR,Ferreira GF,Nunes Neto WR,Monteiro JM,Santos ÁRC,Tavares PB,Denadai ÂML,Bomfim MRQ,Dos Santos VL,Marques SG,de Souza Monteiro A

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND:Recent scientific developments have shed more light on the importance of the host-microbe interaction, particularly in the gut. However, the mechanistic study of the host-microbe interplay is complicated by the intrinsic limitations in reaching the different areas of the gastrointestinal tract (GIT) in vivo....

journal_title：BMC microbiology

authors： Marzorati M,Vanhoecke B,De Ryck T,Sadaghian Sadabad M,Pinheiro I,Possemiers S,Van den Abbeele P,Derycke L,Bracke M,Pieters J,Hennebel T,Harmsen HJ,Verstraete W,Van de Wiele T

更新日期：2014-05-22 00:00:00

abstract：BACKGROUND:Similar to Gram-negative bacteria, the outer membrane (OM) of the pathogenic spirochete, Borrelia burgdorferi, contains integral OM-spanning proteins (OMPs), as well as membrane-anchored lipoproteins. Although the mechanism of OMP biogenesis is still not well-understood, recent studies have indicated that a ...

journal_title：BMC microbiology

authors： Lenhart TR,Kenedy MR,Yang X,Pal U,Akins DR

更新日期：2012-04-20 00:00:00

abstract：BACKGROUND:Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum concentration. Clinical strains of Type B Francisella (F.) tularensis have...

journal_title：BMC microbiology

authors： Ahmad S,Hunter L,Qin A,Mann BJ,van Hoek ML

更新日期：2010-04-23 00:00:00

abstract：BACKGROUND:Brucellosis incidence in China is divided into three stages: high incidence (1950s-1960s), decline (1970s-1980s), and re-emergence (1990s-2010s). At the re-emergence stage, Brucellosis incidence grew exponentially and spread to all 32 provinces. We describe the magnitude and the etiological distribution chan...

journal_title：BMC microbiology

authors： Piao DR,Liu X,Di DD,Xiao P,Zhao ZZ,Xu LQ,Tian GZ,Zhao HY,Fan WX,Cui BY,Jiang H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa is the predominant pathogen associated with the decline of pulmonary function in cystic fibrosis (CF) patients. Both environment-to-host acquisition and patient-to-patient transmission have been described for P. aeruginosa infection. Epidemic clones and bacterial phenotypic adaptation ...

journal_title：BMC microbiology

authors： Cigana C,Melotti P,Baldan R,Pedretti E,Pintani E,Iansa P,De Fino I,Favari F,Bergamini G,Tridello G,Cirillo DM,Assael BM,Bragonzi A

更新日期：2016-07-11 00:00:00

abstract：BACKGROUND:Members of the genus Bifidobacterium are anaerobic Gram-positive Actinobacteria, which are natural inhabitants of human and animal gastrointestinal tract. Certain bifidobacteria are frequently used as food additives and probiotic pharmaceuticals, because of their various health-promoting properties. Due to t...

journal_title：BMC microbiology

authors： Jarocki P,Podleśny M,Komoń-Janczara E,Kucharska J,Glibowska A,Targoński Z

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Biofilm is a fundamental bacterial survival mode which proceeds through three main generalized phases: adhesion, maturation, and dispersion. Lactobacilli spp. (LB) are critical components of gut and reproductive health and are widely used probiotics. Evaluation of time-dependent mechanisms of biofilm formati...

journal_title：BMC microbiology

authors： Martinez S,Garcia JG,Williams R,Elmassry M,West A,Hamood A,Hurtado D,Gudenkauf B,Ventolini G,Schlabritz-Loutsevitch N

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Saudi Arabia is mostly barren except the southwestern highlands that are susceptible to environmental changes, a hotspot for biodiversity, but poorly studied for microbial diversity and composition. In this study, 454-pyrosequencing of 16S rRNA gene hypervariable region V6 was used to analyze soil bacterial ...

journal_title：BMC microbiology

authors： Yasir M,Azhar EI,Khan I,Bibi F,Baabdullah R,Al-Zahrani IA,Al-Ghamdi AK

更新日期：2015-03-14 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis is the foremost oral pathogen of adult periodontitis in humans. However, the mechanisms of bacterial invasion and the resultant destruction of the gingival tissue remain largely undefined. RESULTS:We report host-P. gingivalis interactions in primary human gingival fibroblast (HGF) c...

journal_title：BMC microbiology

authors： Urnowey S,Ansai T,Bitko V,Nakayama K,Takehara T,Barik S

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:Bovicin HC5 is an antimicrobial peptide that shows a broad spectrum of activity and potential for biotechnological and therapeutic applications. To gain insight about the safety of bovicin HC5 application, the histological and immunostimulatory effects of orally administrated bovicin HC5 to BALB/c mice were ...

journal_title：BMC microbiology

authors： Paiva AD,Fernandes KM,Dias RS,Rocha Ados S,Oliveira LL,Neves CA,Paula SO,Mantovani HC

更新日期：2013-03-27 00:00:00

abstract：BACKGROUND:Biofilms are ubiquitous. For instance, the majority of medical infections are thought to involve biofilms. However even after decades of investigation, the in vivo efficacy of many antimicrobial strategies is still debated suggesting there is a need for better understanding of biofilm antimicrobial tolerance...

journal_title：BMC microbiology

authors： Zuroff TR,Bernstein H,Lloyd-Randolfi J,Jimenez-Taracido L,Stewart PS,Carlson RP

更新日期：2010-07-07 00:00:00

abstract：BACKGROUND:Pneumococcus is exposed to a variety of temperature and oxygen levels in the upper respiratory tract and as it invades the lung, tissues, and blood. We sought to determine the effect of environmental variability on growth in vitro and to assess variability between strains. We evaluated the effect of temperat...

journal_title：BMC microbiology

authors： Tóthpál A,Desobry K,Joshi SS,Wyllie AL,Weinberger DM

更新日期：2019-12-26 00:00:00