Abstract：
BACKGROUND:Clinical decision analyses were conducted to quantify the uncertainty and to identify important factors in selection of prophylactic therapy for patients with esophageal varices. METHODS:A Markov model compared variceal ligation, beta-blockers, and "watchful waiting" strategies in terms of bleeding-free life years. Transition probabilities were obtained from meta-analyses of published data. A hypothetical 50-year-old white man with high-risk esophageal varices and cirrhosis served as the prototypical baseline case. Traditional n-way sensitivity analyses were applied to clarify the influence of each factor, and Monte Carlo probabilistic sensitivity analyses were used to investigate clinical uncertainty. RESULTS:Probabilistic sensitivity analyses demonstrated that 77.0% of hypothetical cases had more bleeding-free life years after variceal ligation, whereas 23% had more when treated with beta-blockers. On the basis of one-way sensitivity analyses, only 2 factors (variceal bleeding rates after ligation and treatment with beta-blockers) influenced the strategy choice. CONCLUSIONS:Variceal ligation is an effective prophylactic therapy in many cases, but nearly one quarter of patients with high-risk esophageal varices and cirrhosis may benefit more from prophylactic treatment with beta-blockers. Additional clinical studies identifying key variceal bleeding risk factors may lead to more effective clinical decision making for these patients.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Aoki N,Kajiyama T,Beck JR,Cone RW,Soma K,Fukui Tdoi
10.1067/mge.2000.110729keywords:
subject
Has Abstractpub_date
2000-12-01 00:00:00pages
707-14issue
6eissn
0016-5107issn
1097-6779pii
S0016-5107(00)70181-7journal_volume
52pub_type
杂志文章abstract：:The American Society for Gastrointestinal Endoscopy (ASGE) Technology Committee provides reviews of existing, new, or emerging endoscopic technologies that have an impact on the practice of GI endoscopy. Evidence-based methodology is used by performing a MEDLINE literature search to identify pertinent clinical studies...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,评审
doi：10.1016/j.gie.2010.01.024
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND AND AIMS:Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroent...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2017.01.019
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND AIMS:In patients who undergo cholecystectomy after endoscopic common bile duct (CBD) stone extraction, CBD stones found postoperatively could be problematic. This study aimed to investigate the incidence and risk factors of postoperative CBD stones after cholecystectomy. METHODS:A total of 278 patients ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2020.06.060
更新日期：2020-06-26 00:00:00
abstract：:One hundred colonoscopies were done. The colonoscopist noted whether the cecum had been intubated as well as the markers used to make this determination. With the colonoscope in position at maximum penetration, a radiologist independently determined its position using fluoroscopy, with a contrast agent delivered throu...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(92)70516-1
更新日期：1992-09-01 00:00:00
abstract：:A study of selective sedation for colonoscopy was conducted in two parts. All procedures were performed by one experienced colonoscopist. In the first phase, 41 patients received intravenous sedation before colonoscopy and were then prospectively randomized to either a "not-reversed" group, which did not receive fluma...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND AND AIMS:Effective interventions to prevent residual and/or recurrent adenoma (RRA) after EMR of large sessile and laterally spreading colorectal lesions (LSL) are yet to be determined. RRA may occur due to inconspicuous adenoma at the EMR margin. We aimed to determine the efficacy and safety of extended EMR...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.gie.2016.05.015
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Limited information is available regarding the use of EUS-guided fine-needle aspiration (EUS-FNA) in the diagnosis of lymphoproliferative disorders. The aim of this study was to evaluate the yield of this technique in the primary diagnosis of lymphoma. METHODS:The records were reviewed of 38 consecutive pat...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2001.112841
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Our aim was to compare the clinical efficacy of the Tannenbaum (TB) biliary prostheses, a recently designed Teflon stent without side holes, with the Cotton-Huibregtse (CH) polyethylene stent. METHODS:Fifty-seven patients (26 men, mean age 75.5 years) with unresectable malignant tumors and distal biliary st...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0016-5107(00)70381-6
更新日期：2000-01-01 00:00:00
abstract：:A symptomatic lower esophageal ring generally responds to standard bougienage therapy. However, a subset of patients with a lower esophageal ring defy dilation therapy. We have evaluated the efficacy of electrocautery incision of "defiant" lower esophageal rings, the data of which forms the basis of this report. Seven...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(93)70210-2
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:When choledochoscopic lithotomy with basket and electrohydraulic lithotripsy is used to remove intrahepatic duct stones, fragments or small stones usually remain in the bile duct that are too small to be captured with a basket. METHODS:An attempt was made to remove stone fragments in 16 patients with intrah...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2001.116881
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:Gastric carcinoma is known for its propensity to spread to the peritoneum. This study assessed the value of EUS in the detection of ascites not visible on CT in patients with gastric carcinoma. METHODS:A total of 402 consecutive patients with histopathologically confirmed gastric adenocarcinoma underwent ca...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(03)02873-6
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:To assess capacity for colonoscopy, we need to understand current utilization of colonoscopy in diverse clinical practice settings. The objective of this study was to determine the utilization of colonoscopy in diverse clinical practice settings. METHODS:The Clinical Outcomes Research Initiative (CORI) data...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2005.06.037
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Sporadic non-ampullary duodenal adenomas (SNADAs), although uncommon, pose clinical challenges. Because SNADAs have malignant potential, endoscopic or surgical resection is generally recommended. EMR is increasingly used for resection of SNADAs, but large-scale data on natural history after EMR are ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2017.12.026
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Benign biliary strictures are typically managed endoscopically whereby an increasing size or number of plastic stents is placed at ERCP. Stents are often changed every 3 to 4 months based on the known median patency of a single biliary stent, but patency data for multiple biliary stents are lacking. OBJECTI...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2010.05.029
更新日期：2010-09-01 00:00:00
abstract：:Chronic radiation proctopathy is a common sequela of radiation therapy for malignancies in the pelvic region. A variety of medical and endoscopic therapies have been used for the management of bleeding from chronic radiation proctopathy. In this guideline, we reviewed the results of a systematic search of the literatu...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,实务指引
doi：10.1016/j.gie.2019.04.234
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND AND AIMS:EMR is the primary treatment of large laterally spreading lesions (LSLs) in the colon. Residual or recurrent adenoma (RRA) is a major limitation. We aimed to identify a robust method to stratify the risk of RRA. METHODS:Prospective multicenter data on consecutive LSLs ≥20 mm removed by piecemeal EM...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2016.11.027
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Quality endoscopy reporting is essential when community endoscopists perform colonoscopies for veterans who cannot be scheduled at a Veterans Administration (VA) facility. OBJECTIVE:To examine the quality of colonoscopy reports received from community practices and to determine factors associated with more ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2010.03.002
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:The effect of colon preparation quality on adenoma detection rates (ADRs) is unclear, partly because of lack of uniform colon preparation ratings in prior studies. The New Hampshire Colonoscopy Registry collects detailed data from colonoscopies statewide, by using a uniform preparation quality scale after th...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2014.03.021
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND AND AIMS:Cold snare polypectomy (CSP) and jumbo forceps polypectomy (JFP) have been shown to be effective for removing diminutive colorectal polyps (DCPs) (≤5 mm). However, no study has compared complete resection rates between CSP and JFP for DCPs. The aim of this study was to compare the efficacy and safet...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2019.01.016
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Endoscopic mucosal resection is an established treatment option for early stage gastric cancer. However, several problems with endoscopic mucosal resection remain to be solved, such as appropriate treatment for recurrence and incomplete tumor resection. The outcome for patients undergoing endoscopic aspirati...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2002.129085
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND AND AIMS:The role of electroacupuncture (EA) in reducing sedative and analgesic requirements during EUS is uncertain. The aim of this study was to investigate the efficacy of EA in reducing procedure-related pain and discomfort during EUS. METHODS:This was a double-blinded randomized controlled study conduc...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2017.07.029
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND AND AIMS:The greatest known risk factor for duodenal cancer in familial adenomatous polyposis (FAP) is Spigelman stage (SS) IV duodenal polyposis. Endoscopic surveillance is recommended in FAP patients with SS 0 to IV, and prophylactic duodenectomy should be considered in SS IV. Cancer occurs in patients wit...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2018.07.033
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Confocal laser endomicroscopy (CLE) may be used to diagnose gastric cancer and intestinal metaplasia, but the impact of CLE experience on the accuracy of confocal diagnosis of gastric cancer and intestinal metaplasia is not clear. OBJECTIVE:To establish the sensitivity, specificity, and intragroup interobse...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2011.01.068
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:The hemostatic efficacy of mechanical methods of hemostasis, together with epinephrine injection, was compared with that of epinephrine injection alone in bleeding peptic ulcer. METHODS:Ninety patients with a peptic ulcer with active bleeding or a non-bleeding visible vessel were randomly assigned to underg...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0016-5107(04)01570-6
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND AND AIMS:We developed a suturing method with string and clips for a single-channel endoscope. The feasibility of the string clip suturing method is evaluated in this prospective pilot study. METHODS:This study involved 10 consecutive patients who underwent endoscopic submucosal dissection (ESD) for a duoden...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2017.11.007
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Access to fluoroscopic equipment is limited in some regions where esophageal cancer is common. This report describes a simple method for placement of expandable esophageal stents without fluoroscopy. METHODS:Patients with dysphagia due to unresectable esophageal cancer underwent esophageal stent placement u...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1016/s0016-5107(01)70415-4
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND AND AIMS:False positive (FP) results by computer-aided detection (CADe) hamper the efficiency of colonoscopy by extending examination time. Our aim was to develop a classification of the causes and clinical relevance of CADe FPs, and to assess the relative distribution of FPs in a real-life setting. METHODS...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2020.06.021
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Endoscopic resection is the cornerstone of treatment of Barrett's esophagus (BE)-related neoplasia. However, accurate histopathologic evaluation of endoscopic resection specimens can be challenging, and the preferred specimen handling method remains unknown. Therefore, the aim of our study was to co...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2019.03.014
更新日期：2019-09-01 00:00:00
abstract：:Endoscopic ultrasonography was performed in 25 patients with suspected pancreatic disease. Cancer of the pancreas was recognized in 9 of 10 cases with 1 false negative and 2 false positive diagnoses. Chronic pancreatitis was recognized in 89% of cases. Technical difficulties limited the success of the examination in 2...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(89)72761-9
更新日期：1989-05-01 00:00:00
abstract：BACKGROUND AND AIMS:EUS-guided FNA or biopsy sampling is widely practiced. Optimal sonographic visualization of the needle is critical for image-guided interventions. Of the several commercially available needles, bench-top testing and direct comparison of these needles have not been done to reveal their inherent echog...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2016.01.068
更新日期：2016-09-01 00:00:00
