Dehydroepiandrosterone-dependent induction of peroxisomal proliferation can be reduced by aspartyl esterification without attenuation of inhibitory bone loss in ovariectomy animal model.

abstract：:IMR is useful for assessing the microvascular dysfunction after primary percutaneous coronary intervention (PCI). It remains unknown whether index of microcirculatory resistance (IMR) reflects the functional outcome in patients with anterior myocardial infarction (AMI) with or without microvascular obstruction (MO).Th...

journal_title：Journal of Korean medical science

authors： Yoo SH,Yoo TK,Lim HS,Kim MY,Koh JH

更新日期：2012-09-01 00:00:00

abstract：:Pain is often associated with a more rapid progression of cognitive and functional decline, and behavioral disturbance in dementia. Therefore, it is essential to accurately assesses pain for proper intervention in patients with dementia. The Face, Legs, Activity, Cry, and Consolability (FLACC) scale is an excellent be...

journal_title：Journal of Korean medical science

authors： Moon Y,Kim YS,Lee J,Han SH

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:We aimed to investigate the awareness of human immunodeficiency virus (HIV) infection among high-risk individuals, including men who have sex with men (MSM) and medical personnel (MP) in Korea through a cross-sectional survey, identify possible obstacles hindering their access to pre-exposure prophylaxis (Pr...

journal_title：Journal of Korean medical science

authors： Chang HH,Kim SW,Jung H,Lee SA,Park HK,Kim S,Lee JM,Choi JY

更新日期：2018-03-19 00:00:00

abstract：:The prognostic significance of multidrug resistance (MDR) gene expression is controversial. We investigated whether multidrug resistance gene 1 (MDR1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) mRNA expression are associated with outcomes in acute leukemia patients. At diagnosis we e...

journal_title：Journal of Korean medical science

authors： Huh HJ,Park CJ,Jang S,Seo EJ,Chi HS,Lee JH,Lee KH,Seo JJ,Moon HN,Ghim T

更新日期：2006-04-01 00:00:00

abstract：:The purpose of the study was to define characteristics of children with acute carbon monoxide poisoning. Eighty children hospitalized with acute carbon monoxide poisoning were recruited prospectively over a period of 12 months. Sociodemographic features, complaints and laboratory data were recorded. When the patient w...

journal_title：Journal of Korean medical science

authors： Unsal Sac R,Taşar MA,Bostancı İ,Şimşek Y,Bilge Dallar Y

更新日期：2015-12-01 00:00:00

abstract：:Cardiac autonomic neuropathy (CAN) is a common and most neglected complication of diabetes, estimated to be roughly 8% in recently diagnosed patients and greater than 50% in patients with chronic disease history. The insulin resistance (IR) itself is bidirectionally associated with increased risk of type 2 diabetes me...

journal_title：Journal of Korean medical science

authors： Akbar M,Bhandari U,Habib A,Ahmad R

更新日期：2017-07-01 00:00:00

abstract：:We investigated the incidence of unsuspected gallbladder (GB) carcinomas in a total of 527 consecutive GB specimens resected for benign biliary disease and their clinicopathological features. The GBs were examined microscopically using stepwise tissue sections at 5 mm interval. Clinical and pathological findings were ...

journal_title：Journal of Korean medical science

authors： Kwon SY,Chang HJ

更新日期：1997-12-01 00:00:00

abstract：:Middle East respiratory syndrome (MERS) is a lethal respiratory disease - caused by MERS-coronavirus (MERS-CoV) which was first identified in 2012. Especially, pregnant women can be expected as highly vulnerable candidates for this viral infection. In May 2015, this virus was spread in Korea and a pregnant woman was c...

journal_title：Journal of Korean medical science

authors： Jeong SY,Sung SI,Sung JH,Ahn SY,Kang ES,Chang YS,Park WS,Kim JH

更新日期：2017-10-01 00:00:00

abstract：:This study aimed to estimate nationwide prevalence of the metabolic syndrome and to identify its association with cardiovascular diseases. The data on a national representative sample of 6,147 adults from 1998 Korea National Health and Nutrition Survey were analyzed. The syndrome was determined according to two kinds ...

journal_title：Journal of Korean medical science

authors： Kim MH,Kim MK,Choi BY,Shin YJ

更新日期：2004-04-01 00:00:00

abstract：:Difference in crude neonatal and infant mortality rates (NMR and IMR) among different countries is due to the differences in its two determinants: birth weight distribution (BWD) and birth weight-specific mortality rates (BW-SMRs). We aimed to determine impact of BWD and BW-SMRs on differences in crude NMR and IMR amo...

journal_title：Journal of Korean medical science

authors： Kim do H,Jeon J,Park CG,Sriram S,Lee KS

更新日期：2016-09-01 00:00:00

abstract：:Increased epithelial cell proliferation is associated with an increased risk of gastric carcinoma. Helicobacter pylori infection is an established risk factor for gastric cancer and the organism has recently been classified as a group I carcinogen by an IARC working group. In this study, we describe differences in gas...

journal_title：Journal of Korean medical science

authors： Jang TJ,Lee JI,Kim JR,Kim DH,Bae SH

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:This study described and analysed the features of powered mobility device (PMD)-related injuries and compared elderly and younger adult injuries. METHODS:Data from Korea Emergency Department-based Injury In-depth Surveillance (EDIIS) database involving eight emergency departments in 2011-2016 were analysed....

journal_title：Journal of Korean medical science

authors： Shin Y,Cha WC,Yoon H,Hwang SY,Shin TG,Sim MS,Jo IJ,Kim T

更新日期：2020-03-09 00:00:00

abstract：:When access to a major duodenal papilla or endoscopic retrograde cholangiopancreatography has failed, percutaneous transhepatic cholangioscopic lithotripsy (PTCS-L) may be useful for removing common bile duct (CBD) stones. However, the feasibility and usefulness of percutaneous transhepatic papillary large-balloon dil...

journal_title：Journal of Korean medical science

authors： Han JY,Jeong S,Lee DH

更新日期：2015-03-01 00:00:00

abstract：:In 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Kore...

journal_title：Journal of Korean medical science

authors： Park HY,Nam HS,Chung MP,Jeong SH,Kim YJ,Cha SI,Kim YW,Park JS,Uh ST,Park CS,Park MS,Moon JA,Jung KS,Jegal YJ,Kim DS,Song JW,Yum HK,Park YB

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to present and analyze, for the first time, the results of a government-supported nationwide newborn hearing screening (NHS) pilot project in the 17 major cities and provinces of Korea. METHODS:We analyzed a nationwide NHS database of 344,955 newborns in the pilot project from 2014...

journal_title：Journal of Korean medical science

authors： Chung YS,Oh SH,Park SK

更新日期：2020-08-10 00:00:00

abstract：:The purpose of this study was to investigate the differences in subjective acute effects of alcohol and naltrexone among those who prefer spicy food to varying degrees. Acute biphasic alcohol effects scale (BAES), visual analogue scale for craving (VAS-C), blood alcohol concentration (BAC) and food preference scale we...

journal_title：Journal of Korean medical science

authors： Lee JS,Kim SG,Jeong HJ,Kim JH,Yang YH,Jung WY

更新日期：2014-05-01 00:00:00

abstract：:Blood pressure (BP) control is considered the most important treatment for preventing chronic kidney disease (CKD) progression and associated cardiovascular complications. However, clinic BP is insufficient to diagnose hypertension (HT) and to monitor overall BP control because it does not correlate well with ambulato...

journal_title：Journal of Korean medical science

authors： Oh YK,Chin HJ,Ahn SY,An JN,Lee JP,Lim CS,Oh KH

更新日期：2017-05-01 00:00:00

abstract：:Neuroblastomas originating from different sites might have different clinical and biological characteristics. In the present study, the clinical (age, sex and stage) and biological (N-myc amplification, Shimada pathology and levels of lactate dehydrogenase, ferritin and neuron-specific enolase) characteristics of pati...

journal_title：Journal of Korean medical science

authors： Sung KW,Yoo KH,Koo HH,Kim JY,Cho EJ,Seo YL,Kim J,Lee SK

更新日期：2009-06-01 00:00:00

abstract：:A patient with a fulminant amebic colitis coexisting with intestinal tuberculosis had a sudden onset of crampy abdominal pain, mucoid diarrhea, anorexia, fever and vomiting with signs of positive peritoneal irritation. Fulminant amebic colitis occurring together with intestinal tuberculosis is an uncommon event and ma...

journal_title：Journal of Korean medical science

authors： Park SC,Jeon HM,Kim JS,Kim WW,Kim KW,Oh ST,Kim EK,Chang SK,Lee EJ

更新日期：2000-12-01 00:00:00

abstract：:The aim of this study was to assess the effectiveness of active intervention with antenatal maternal corticosteroid and antibiotics therapy in infants delivered between 24 and 28 weeks of gestation after premature rupture of membrane. This retrospective study included pregnant women complicated by preterm delivery at ...

journal_title：Journal of Korean medical science

authors： Song GA,Han MS

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:The purpose was to compare the efficacy between tenofovir disoproxil fumarate (TDF) and lamivudine (LMV) in children with nucleos(t)ide-naive chronic hepatitis B (CHB) infection. Patients with CHB were treated with TDF in the immune-reactive phase and compared with a historical control group of patients trea...

journal_title：Journal of Korean medical science

authors： Choe JY,Ko JS,Choe BH,Kim JE,Kang B,Lee KJ,Yang HR

更新日期：2018-01-08 00:00:00

abstract：Background:The zoonotic disease Q fever is caused by Coxiella burnetii and usually affects high-risk human populations. We conducted a serological survey of dairy cattle farmers in Korea to determine seroreactivity and identify risk factors for C. burnetii infection. Methods:This cross-sectional study included 1,824 o...

journal_title：Journal of Korean medical science

authors： Park JH,Chu H,Yoo SJ,Hwang KJ,Lim HS

更新日期：2018-08-16 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in folate metabolism, plays an important role in DNA methylation. It has been suggested that abnormal DNA methylation contributes to the pathogenesis of schizophrenia and congenital anomalies. The previous findings regarding the genetic relationship betwee...

journal_title：Journal of Korean medical science

authors： Kim SG,Song JY,Joo EJ,Jeong SH,Kim SH,Lee KY,Lee NY,Ahn YM,Kim YS,Roh MS

更新日期：2011-10-01 00:00:00

abstract：:The risk factors related to hepatitis C virus (HCV) infection showed geographic and temporal differences. We investigated HCV-related risk factors in Korea where intravenous drug use (IVDU) is uncommon. The HCV-related risk factors were investigated in a prospective, multicenter chronic HCV cohort (n = 711) using a st...

journal_title：Journal of Korean medical science

authors： Kim JY,Cho J,Hwang SH,Kil H,Bae SH,Kim YS,Lee HC,Jeong SH

更新日期：2012-11-01 00:00:00

abstract：:A case of Cushing's syndrome due to bilateral pigmented nodular adrenal disease in a 35-year-old male is presented. The adrenals showed multiple, black, variable sized nodules. Histologically the cells contained lipofuscin and either had a clear cytoplasm or an eosinophilic cytoplasm with a prominent nucleus. Lymphocy...

journal_title：Journal of Korean medical science

authors： Park YK,Kim YW,Kim JW,Choi YK,Ko YT,Ko SW,Yang MH

更新日期：1994-12-01 00:00:00

abstract：:Classic hemophilia, (hemophilia A), is an X-linked hereditary bleeding disorder affecting half of the male offspring of female carriers. Prenatal diagnosis offers an option, namely to restrict abortions to hemophilic fetuses only, and thus retain the chance of bearing normal sons. Recently, the authors have made a pre...

journal_title：Journal of Korean medical science

authors： Song KS,Lee A,Lee K,Lee BS

更新日期：1992-06-01 00:00:00

abstract：:The plasma ghrelin has been reported to be elevated in Prader-Willi syndrome (PWS) and modulated by insulin. It was hypothesized that insulin might have a more pronounced effect on reducing plasma ghrelin in PWS patients, which would influence appetite. This study investigated the degree of ghrelin suppression using a...

journal_title：Journal of Korean medical science

authors： Paik KH,Lee MK,Jin DK,Kang HW,Lee KH,Kim AH,Kim C,Lee JE,Oh YJ,Kim S,Han SJ,Kwon EK,Choe YH

更新日期：2007-04-01 00:00:00

abstract：:Benign recurrent hematuria usually indicates a good prognosis. This condition is associated with abnormally thin glomerular basement membranes. Of 680 renal biopsy cases in which lower urinary tract disease had been excluded by careful study, 25 cases from seven children and eighteen adults met the criteria for thin g...

journal_title：Journal of Korean medical science

authors： Suh KS,Kim JO,Kang GH

更新日期：1997-06-01 00:00:00

abstract：:Telomerase play a key role in the maintenance of telomere length and chromosome integrity. We have evaluated the association between telomerase activity and the risk of lung cancer in peripheral blood. Telomerase activity in peripheral blood mononuclear cells was measured by a PCR-designed telomeric repeat amplificati...

journal_title：Journal of Korean medical science

authors： Jeon HS,Choi JE,Jung DK,Choi YY,Kang HG,Lee WK,Yoo SS,Lim JO,Park JY

更新日期：2012-02-01 00:00:00

abstract：:Maspin is a unique serine proteinase inhibitor that has tumor suppressor activity. It has been reported that maspin is expressed in normal human mammary epithelial cells and it is down-regulated during the progression of cancer. However, to date, there is very limited data on the clinical significance of maspin expres...

journal_title：Journal of Korean medical science

authors： Lee MJ,Suh CH,Li ZH

更新日期：2006-04-01 00:00:00