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A genetic analysis of crystal growth.

Abstract：

:The regulation of crystal morphology by proteins is often observed in biology. It is a central feature in the formation of hard tissues such as bones, teeth and mollusc shells. We have developed a genetic system in the bacterium Escherichia coli to study the protein-mediated control of crystal growth. We have used the crystallization of gold as a model system and found polypeptides that control the morphology of the resulting gold crystals. Analysis of the crystallization process influenced by these polypeptides indicates they act catalytically by an acid mechanism. Our results suggest that the concepts and methods of microbial genetics are general and can be applied to substances not commonly found in biological systems.

journal_name

J Mol Biol

journal_title

Journal of molecular biology

authors

Brown S,Sarikaya M,Johnson E

doi

10.1006/jmbi.2000.3682

keywords:

subject

Has Abstract

pub_date

2000-06-09 00:00:00

pages

725-35

issue

3

eissn

0022-2836

issn

1089-8638

pii

S0022-2836(00)93682-9

journal_volume

299

pub_type

杂志文章

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