Seroconversion following killed polio vaccine in neonates.

Abstract:

:The study was carried out to evaluate the efficacy of IPV in neonates and to study the additive effect of IPV or OPV at birth on seroconversion with three subsequent doses of OPV. Addition of IPV or OPV at birth to the conventional OPV schedule resulted in significantly higher seroconversion rates than in the controls, who received three doses of OPV. Three doses of IPV beginning from birth resulted in significantly better seroconversion rates than in the control group. Children receiving 3 doses of IPV showed significantly greater seroconversion rates against type III polio virus than those receiving IPV/OPV at birth followed by 3 doses of OPV. The difference in the seroconversion rates against the other virus types was not significant. A significantly greater number of children who received some vaccine at birth (IPV or OPV) were protected against poliomyelitis by 6 weeks age as compared to those who received no immunization at birth. The study recommends that seroconversion rates following three doses of IPV are satisfactory. Addition of IPV or OPV at birth to the conventional schedule markedly increases the seroconversion rates. Immunization can be started at birth to ensure early protection against poliomyelitis.

journal_name

Indian J Pediatr

authors

Jain PK,Dutta AK,Nangia S,Khare S,Saili A

doi

10.1007/BF02737758

keywords:

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

511-5

issue

4

eissn

0019-5456

issn

0973-7693

journal_volume

64

pub_type

临床试验,杂志文章,随机对照试验
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    doi:10.1007/BF02724106

    authors: Bhatt M,Anil SR,Sivakumar K,Kumar K

    更新日期:2004-04-01 00:00:00

  • Hydrocephalus with cleft lip and palate: an overlap between midline malformation syndromes.

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    doi:10.1007/BF02898455

    authors: Cakir M,Mungan I,Makuloglu M,Okten A

    更新日期:2006-08-01 00:00:00

  • Non benign neonatal arrhythmias observed in a tertiary neonatal intensive care unit.

    abstract:OBJECTIVE:To analyze non benign neonatal arrhythmias (NA) observed in a tertiary neonatal intensive care unit (NICU). METHODS:From June 2006 through July 2011, newborns admitted to the NICU for NA or diagnosed as NA after hospitalization were evaluated retrospectively. The newborns with non benign NA were included in ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-012-0852-3

    authors: Kundak AA,Dilli D,Karagöl B,Karadağ N,Zenciroğlu A,Okumuş N,Doğan V,Uzunalıç N

    更新日期:2013-07-01 00:00:00

  • Hypophosphatemic rickets: easy to diagnose, difficult to treat.

    abstract::Hypophosphatemic rickets (HR) has generated a lot of interest in recent times. There is need to recognize this disorder and differentiate it from the more common nutritional rickets because the therapy is different. It is also important to emphasize that a detailed clinical examination with pedigree analysis and easil...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02723852

    authors: Garg RK,Tandon N

    更新日期:1999-11-01 00:00:00

  • Modifiable risk factors for acute lower respiratory tract infections.

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    pub_type: 杂志文章

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    authors: Savitha MR,Nandeeshwara SB,Pradeep Kumar MJ,ul-Haque F,Raju CK

    更新日期:2007-05-01 00:00:00

  • Designing a research study.

    abstract::There are 10 steps to consider in any research study. These steps can be used to perform a critical appraisal of a published paper, or to design your study in the first place. The use of a simple system such as this can ensure that biases in study design are avoided and that an appropriate study is developed. (1) What...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02802638

    authors: Heller R

    更新日期:2000-01-01 00:00:00

  • Recurrent meningitis secondary to isolated C3 deficiency.

    abstract::A 5-year-old child presented with the second episode of meningitis when we started investigating her to find a cause for recurrent episode of meningitis. During this she suffered from a third attack after which she was diagnosed as having isolated C(3) deficiency. She was put on penicillin prophylaxis and vaccinated a...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-009-0036-y

    authors: Singh DK,Rai R

    更新日期:2009-01-01 00:00:00

  • Effect of parental training in managing the behavioral problems of early childhood.

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    pub_type: 杂志文章

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    authors: Srivastava M,Gupta A,Talukdar U,Kalra BP,Lahan V

    更新日期:2011-08-01 00:00:00

  • Status epilepticus in Indian children in a tertiary care center.

    abstract:OBJECTIVE:To study the clinical profile, immediate outcome and possible risk factors of SE in pediatric age group admitted to pediatric intensive care unit (PICU) in a tertiary care center. METHODS:A retrospective study of case records of 451 neuroemergency patients admitted in PICU in a tertiary care center between J...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02760691

    authors: Gulati S,Kalra V,Sridhar MR

    更新日期:2005-02-01 00:00:00

  • Prevalence of cryptosporidium in children with acute diarrhea.

    abstract::Cryptosporidium is an intestinal protozoa known to cause diarrhea in animals and more recently has been recognised as a cause of diarrhea in humans. The present study was designed to determine the prevalence of cryptosporidium as a cause of diarrhea in children. Faecal samples of 180 children admitted to the hospital ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02749728

    authors: Pherwani AV,Bhave SY,Bijm AM,Desai AG

    更新日期:1989-01-01 00:00:00

  • Vitamin A status of socio-economically backward children.

    abstract::A comprehensive survey was carried out to asses the Vitamin A status of pre-school (0-6 yrs). and school age (6-12 yrs.) children of socio-economically backward families from slums of Bombay and its suburbs. The Vitamin A, protein, calories and iron from the rice and dal based diet was found to be below recommended di...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02755061

    authors: Aspatwar AP,Bapat MM

    更新日期:1995-07-01 00:00:00

  • Predictors of stress among parents in pediatric intensive care unit: a prospective observational study.

    abstract:OBJECTIVE:To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at l...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-014-1415-6

    authors: Aamir M,Mittal K,Kaushik JS,Kashyap H,Kaur G

    更新日期:2014-11-01 00:00:00

  • Trends in cerebral palsy.

    abstract::The terms trend and cerebral palsy are defined emphazing the non-diagnostic nature of the cerebral palsy label. Criteria necessary for valid estimation of trends include constant methods of estimating population based numerators and denominators over a number of years, which render them hard to obtain, particularly in...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02723024

    authors: Blair E

    更新日期:2001-05-01 00:00:00

  • Process evaluation of pulse polio immunisation in Delhi.

    abstract::The aim of the study was to assess the functional aspects and the staffing at Pulse Polio immunisations posts. Interns and medical students conducted the survey in eighty seven pulse polio immunisation posts scattered all over National Capital Territory of Delhi on 18th January 1997. A pre-tested structured format con...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02730902

    authors: Kumar P,Pandit K,Chhabra P,Bhasin S,Aggarwal OP

    更新日期:1998-07-01 00:00:00

  • Genetic counseling.

    abstract::Genetic counseling is a process of communicating medical aspects about a genetic disorder, especially the information regarding risk of occurrence as recurrence of the disease in the family and preventive options. Accurate diagnosis of the affected member is of paramount importance for genetic counseling. Special gene...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02723098

    authors: Phadke SR

    更新日期:2004-02-01 00:00:00

  • Clinical Approach to a Neonate with Cyanosis.

    abstract::Cyanosis is always pathological and demands detailed evaluation. Combined use of clinical findings, electrocardiogram and chest radiograph permits determination of underlying cause in vast majority. Stepwise approach allows hemodynamic classification of the cardiac lesion and directs immediate management. Accurate ana...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-015-1871-7

    authors: Gupta SK

    更新日期:2015-11-01 00:00:00

  • Medical bioethics and cultural diversity.

    abstract::Medical bioethics has developed as a new field of study in the US in the past quarter decade, focusing upon the moral principles of autonomy, beneficence, nonmaleficence, and justice. These principles may, however, reflect biases in American culture, rather than a truly universal approach to ethical problems in medici...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/BF02845196

    authors: Brody H

    更新日期:1997-05-01 00:00:00

  • Psychosocial problems in families of children with cancer.

    abstract:OBJECTIVE:The aim of this study is to assess the effect of diagnosis of cancer on the parents, to study the coping response adopted by the child and the family and to evolve counseling strategies. METHODS:Prospective questionnaire based. Thirty-four parents of children suffering from cancer were included, of which 15 ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-007-0149-0

    authors: Rajajee S,Ezhilarasi S,Indumathi D

    更新日期:2007-09-01 00:00:00

  • Randomized double blinded controlled trial to evaluate the efficacy and safety of Bifilac in patients with acute viral diarrhea.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of Bifilac on reducing the episodes (frequency) and duration of diarrhea induced by rotaviral infection and to evaluate the efficacy of Bifilac to ameliorate the associated symptoms like dehydration and duration of rotaviral shedding in faeces. METHODS:80 children aged bet...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12098-008-0134-2

    authors: Narayanappa D

    更新日期:2008-07-01 00:00:00

  • Meropenem in neonatal severe infections due to multiresistant gram-negative bacteria.

    abstract::Recently, new broad spectrum carbapenem has been investigated on a world-wide scale for the treatment of moderate to severe infections. In the neonatal intensive care units the extensive use of third generation cephalosporins for therapy of neonatal sepsis may lead to rapid emergence of multiresistant gram-negative or...

    journal_title:Indian journal of pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02728850

    authors: Köksal N,Hacimustafaoğlu M,Bağci S,Celebi S

    更新日期:2001-01-01 00:00:00

  • Association of Child Neurology-Indian Epilepsy Society Consensus Document on Parental Counseling of Children with Epilepsy.

    abstract::When a child is diagnosed with epilepsy, counseling regarding the same is done by the treating doctor. Most parents are frightened and have poor knowledge about epilepsy. Therapeutic advice including drug dosage, administration and side effects takes up the major part of physician's time, thereby neglecting important ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-019-02946-z

    authors: Srivastava K,Sehgal R,Konanki R,Jain R,Sharma S,Mittal R,Association of Child Neurology (AOCN)-Indian Epilepsy Society (IES) SOLACE Expert Group.,Hedge A,Aggarwal A,Chattopadhyay A,Patra B,Kaushik JS,Lingappa L,Sankhyan N,Kap

    更新日期:2019-07-01 00:00:00

  • Epidemiology and pathophysiology of Helicobacter pylori infection in children.

    abstract::Helicobacter pylori is one of the commonest bacterial pathogens in human. The organism is associated with development of peptic ulcer diseases, lymphoproliferative disorders and gastric cancer. Residence in a developing country, poor socio-economic conditions and genetic predisposition are regarded as risk factors. Pr...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-007-0046-6

    authors: Das JC,Paul N

    更新日期:2007-03-01 00:00:00

  • Round pneumonia in children.

    abstract::We evaluated four children with rounded densities on their chest radiographs in whom the final diagnosis was presumed to be lower respiratory tract infection. The differential diagnose between round pneumonia and a neoplastic process is difficult to make. In this report, all of cases of round pneumonia have resolved c...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/s12098-008-0085-7

    authors: Celebi S,Hacimustafaoglu M

    更新日期:2008-05-01 00:00:00

  • Longitudinally Extensive Transverse Myelitis.

    abstract:: ...

    journal_title:Indian journal of pediatrics

    pub_type: 信件

    doi:10.1007/s12098-018-2702-4

    authors: Chawla D,Mishra D,Singh S,Juneja M

    更新日期:2019-01-01 00:00:00

  • Manual and pump methods of expression of breast milk.

    abstract::This study was designed to compare two methods of breast milk expression, namely, the manual and the pumping method using a hand-held cylindric pump. The parameters evaluated were (i) the output of breast milk during milk expression sessions of 15 minutes' duration, and, (ii) the subjective preference of the method by...

    journal_title:Indian journal of pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02823873

    authors: Paul VK,Singh M,Deorari AK,Pacheco J,Taneja U

    更新日期:1996-01-01 00:00:00

  • Moebius syndrome with total anomalous pulmonary venous connection.

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    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02758568

    authors: Suvarna J,Bagnawar M,Deshmukh CT

    更新日期:2006-05-01 00:00:00

  • The congenital long QT syndrome.

    abstract:OBJECTIVE:The long QT syndrome (LQTS) is a disorder of the electrical system of the heart, due to dysfunction of the ion channels and involving the repolarisation process. The inherited form occurs when there is a mutation in one of the genes which encode the making of a channel. Prolongation of the QT interval renders...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02859375

    authors: Shanbag P,Govindakumar PT,Vaidya M,Joshi V,Shahid SK

    更新日期:2002-02-01 00:00:00

  • Early Life Origins of Obesity and Related Complications.

    abstract::The idea that nutrition in early life (such as before conception, during pregnancy and in infancy) can influence, or programme, long-term health, known as the 'Developmental Origins of Health and Disease Hypothesis', has generated great scientific interest. This concept is particularly relevant for the development of ...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-017-2554-3

    authors: Singhal A

    更新日期:2018-06-01 00:00:00

  • Use of appendix in biliary atresia.

    abstract::Antiperistaltic appendiceal conduit based on its vascular pedicle was used as hepaticoporto-appendico-jejunostomy (HAJ) in 9 infants with advanced stage of biliary atresia. Operative procedure was simple and less time consuming. The postoperative cholangitis was conspicuously absent, possibly due to the role played by...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章

    doi:10.1007/BF02722419

    authors: Gupta DK,Rohatgi M

    更新日期:1989-07-01 00:00:00

  • Approach to a child with sore throat.

    abstract::Sore throat is one of the common reasons for outpatient and emergency visits among children. It could be because of several etiologies; of these bacterial pharyngitis is the most important. Major challenge for the clinician is to diagnose group A beta hemolytic streptococcus (GABHS) pharyngitis and diphtheria, which a...

    journal_title:Indian journal of pediatrics

    pub_type: 杂志文章,评审

    doi:10.1007/s12098-011-0467-0

    authors: Shah R,Bansal A,Singhi SC

    更新日期:2011-10-01 00:00:00