Abstract：
:The role of Tissue Factor (TF, thromboplastin) as the major factor in initiation of the blood coagulation process has been known for more than 100 years. Its importance for the development of clinical thrombosis, be it venous or arterial, and the complexity of the cell biology of TF, have however been increasingly appreciated over the past 15-20 years. Acting as a cofactor for coagulation factor VIIa, it is now clear that TF is able to activate factor IX. Aberrant expression of TF seems to play a major role in the intravascular coagulations disorders linked to endotoxemia, malignancies, immunological diseases and atherosclerosis. Tissue Factor Pathway Inhibitor (TFPI) is the natural direct inhibitor of TF/FVIIa complex. In this study the physiological role, mechanism of action and pharmacological potential of TFPI are discussed.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Camici M,Sagripanti Akeywords:
subject
Has Abstractpub_date
1999-01-01 00:00:00pages
25-32issue
1-2eissn
0026-4806issn
1827-1669journal_volume
90pub_type
杂志文章,评审相关文献
MINERVA MEDICA文献大全abstract：:The authors notice a prevalence of P. falciparum in eight observed cases of imported malaria and confirm the increasing polychemioresistance of plasmodium and its prophylactic and therapeutic problems. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Coronary performance was evaluated in 18 men and 6 women by i.v. infusion of increasing doses of isoproterenol and minute-by-minute ECG monitoring. The results appeared fully reliable. In some cases where the conditions for effort testing were satisfied a comparison was made with the cycle-ergometer findings. This sho...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-04-14 00:00:00
abstract：BACKGROUND:The purpose of this study was to evaluate, by Stress-Exercise Electrocardiography (SE), the presence of Coronary Artery Disease (CAD) in patients with asymptomatic or symptomatic carotid stenosis, who had no history of myocardial ischemia. MATERIALS, METHODS AND RESULTS:133 patients with significant carotid...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:The causa mortis of Napoleon Bonaparte has been vexata quaestio for a long time. The author tries to outline a picture of Napoleon from a sanitary point of view. From the report of doctor Francesco Antonmarchi who performed the autopsy, the author tries to understans the cause of death: gastric perforation due to mali...
journal_title：Minerva medica
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:A long-surviving clinical case of suspected Morquio's syndrome is described. The locomotorium (vertebral dwarfism, hyphoscoliosis, but no hypoplasia of the odontoid process of the epistropheus, platyspondylia), cardiopulmonary (aortic insufficiency, arterial calcification, varices) visual (opaque lens on right eye, sc...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-10-27 00:00:00
abstract：BACKGROUND:A case of Still's disease in the adult, an uncommon seronegative rheumatoid arthritis-like disease with prominent systemic features is reported. This case did not show the typical clinical features and appeared like a fever of unknown origin. CASE REPORT:A 60 year-old female was admitted to the hospital for...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:New direct antiviral agents (DAA) are now effective in hepatitis C virus (HCV) infection; persons living with human immunodeficiency virus (HIV) (PLWH) were undertreated. Aim of this study was to describe the management of HCV treatment in a HIV/HCV cohort during a 16 years period. METHODS:An electronic rev...
journal_title：Minerva medica
pub_type： 杂志文章
doi：10.23736/S0026-4806.18.05435-6
更新日期：2018-06-01 00:00:00
abstract：:4 cases of duodenal ulcer, diagnosed by gastroscopic examinations three of which were already treated medically with insufficient results, are presented. Acupuncture was carried out several times (about 5 to 7) during 1-2 months and gave rise to a complete disappearance of the clinical symptoms and complete healing of...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-11-03 00:00:00
abstract：:We report the results obtained with intravenous immunoglobulin (IVGG) in 15 patients suffering from Guillain Barré syndrome (GBS) with substantial motor damage. All of them met the NINCDS criteria for a diagnosis of certain GBS and were graded using a specific scale on entry, after 2 weeks, one month, two months, six ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:The aim of this study is to verify the therapeutical effect of acupuncture reflexotherapy in low back pain treatment and to test if the number of sessions could influence the results at the end of therapy. METHODS:Thirty-one patients, suffering from low back pain, were randomly divided into 2 groups: the first gro...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-08-01 00:00:00
abstract：:Postoperative CT of the latero-cervical lymph nodes was carried out in 25 patients suffering from laryngeal cancer. The surgically removed lymph nodes themselves were measured and examined histologically. 529/621 removed lymph nodes (about 85%) were recognisable with CT. The metastasized lymph nodes were clearly ident...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
abstract：AIM:To investigate the hippocampal regional deformation modes by means of a novel method of automatic segmentation for discriminating between Alzheimer's disease (AD) and normal aging; and to further provide the effective evidence for the early diagnosis of AD. METHODS:Twenty AD patients and sixty healthy volunteers w...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2014-04-01 00:00:00
abstract：:The action of alpha-mercaptopropionylglycine has been studied in 27 subjects occupationally exposed to lead. In addition to improved efficiency of liver function, the results show a tendency to normalization of the various porphyrinic metabolism parameters considered. A significant increase was observed in erythrocyte...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1979-09-26 00:00:00
abstract：:Observations in the past decade in Veneto and Calabrian hospitals of cases of advanced pathology such as giant uterine fibromas suggest some clinico-statistical and medico-social considerations. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-04-21 00:00:00
abstract：:Variations in the flow/volume curve have been examined in normal subjects in relation to age. It was noted that although flow varies in absolute terms, its fall is constant in both men and women, at equal age. On the other hand, a flow reduction first of 25% and then 50% of CVF was noted in relation to age. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1978-01-31 00:00:00
abstract：:The diagnostic role of carcinoembryonic antigen (CEA) in ascitic fluid was evaluated in order to assess whether or not ascitic haemorrhage is related to cancer. A total of 30 patients with ascitic haemorrhage were analysed (17 had cirrhosis, 5 non-metastasised cancers and 8 metastasised cancers). CEA radioimmunoassay ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-06-08 00:00:00
abstract：:The presence of a low T3 syndrome was confirmed in elderly euthyroid patients. The condition is characterised by lower circulating total (TT3) and free triiodothyronin (FT3) than in adults with no clinical symptoms of hypothyroidism. A total of 133 subjects over 65 were studied as we used 204 adult controls aged 18-65...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1987-01-15 00:00:00
abstract：:The IATA regulations on the scheduled flight transportation of sick passengers is presented and the problems involved illustrated. Among other recommendations it is suggested that collaboration with the patients' doctors in filling up the MEDIF form is essential for the sick passenger's comfort and safety. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-08-25 00:00:00
abstract：:The combination of ear buzzing and cervical arthrosis is frequently encountered in both ENT practice and physiatry. A group of 16 patients presenting this combination was therefore selected. After a series of ENT and physiatric tests the patients were subjected to audiological and radiographic examination in order to ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1987-06-30 00:00:00
abstract：:Correction of incontinence as the sequel of a pull-through operation for anorectal atresia, leaving aside cases due to a mistake of the surgical technique, is based on the construction of a new sphincter. This can be done in several ways, using striped, pedicled, denervated, free, or, more recently, smooth muscle. The...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-10-13 00:00:00
abstract：:The risk of atherosclerotic or hypertensive cardiovascular disease increases after physiological or surgical menopause, irrespective of whether or not the ovaries are removed. In order to evaluate the direct contribution of the uterus in cutting down the incidence of cardiovascular diseases, the clinical records of 15...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-04-28 00:00:00
abstract：BACKGROUND:To study the efficacy of cisplatin-loaded M1 macrophage secreted-exosomes (DDP-M1-Exos) in enhancing DDP anti-tumor effect. METHODS:M1-Exos were first extracted using density gradient centrifugation, and the DDP-M1-Exos system was established via electroporation. Then, the morphology, particle size and make...
journal_title：Minerva medica
pub_type： 杂志文章
doi：10.23736/S0026-4806.20.06564-7
更新日期：2020-04-08 00:00:00
abstract：:15 male heroin addicts, 19-26 yr, were given 20 hospital treatments for detoxifying. Therapeutic program was based on GABAergic drugs (1-glutamine, sodium valproate, pyridoxine), low doses psychodrugs and acupuncture, added from the 3rd day. A full avoidance of the withdrawal syndrome was reached in 15 out of 18 Ss so...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-03-31 00:00:00
abstract：:A simple routine endoscopic screening test has been sought for the diagnosis of chronic atrophic gastritis. An endoscopic-bioptic study was therefore carried out on 850 subjects presenting consecutively at a Digestive Endoscopy Department with dyspeptic-pain symptomatology. In a first sample of 389 patients, 2 biopsie...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：:A randomized and double blind experiment has been made over 50 patients and 25 checks, by giving a dosage of 3 Fosfolip (calcium salt of phosphorylcholine chlorid with pantethine) capsules a day. The analysis results has been reported in the work. In none case the product had secondary no desired effects; while therap...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1983-04-07 00:00:00
abstract：:Twenty-three patients with orthopedic and traumatic disorders, mostly hospitalized, were treated with proglumetacin, 450 mg/day, during 5-45 days. Proglumetacin resulted to be a good analgesic and anti-inflammatory drug. Tolerance was good or excellent in all patients but one. Proglumetacin appears to be drug particul...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-06-23 00:00:00
abstract：:Acute suppurative thyroiditis is an acute disease of the thyroid gland. In this paper the authors report a case of acute suppurative thyroiditis complicated by abscessual evolution in an addict patient study with ultra-sonography and treated with fine needle aspiration and antibiotic therapy. The patient reached our o...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Current estimates of the prevalence of chronic pancreatitis, one of the most common causes of exocrine pancreatic insufficiency, are in the range of 3-10 per 100,000 people in many parts of the world. Alcohol consumption is a very important risk factor for exocrine pancreatic insufficiency and is involved in nearly ha...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4806.19.06043-9
更新日期：2019-10-01 00:00:00
abstract：:In Italy, the attitude displayed by psychosomatists towards hypnosis and A.T. is decidedly favourable, since they are considered as forms of short-term psychotherapy, this being primarily indicated in the management of psychosomatosis. While some reservations may be expressed with regard to the employment of hypnosis ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-10-31 00:00:00
abstract：:Popliteal cysts presenting as thrombophlebitis are unusual diseases of the popliteal fossa and are commonly associated with rheumatoid arthritis or meniscal tears. The authors report the case of a 38-year-old man with Reiter's syndrome in which a synovial cyst of the popliteal space, mimicking symptoms suggestive of d...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：1995-09-01 00:00:00
