ECG of the "newborn" mouse (Mus domesticus) with specific reference to comparative AV transmission.

Abstract:

INTRODUCTION:The objective of this study was to record the ECG of the smallest living mammal to extend the domain of data for comparative AV nodal electrophysiologic purposes. These data are needed to establish the relationship between the PR interval and heart size in mammalian species of all sizes. METHODS AND RESULTS:In recently born mice (age 1.5 to 8 weeks) weighing between 2.5 and 10 g and with estimated heart weights between 15 and 60 mg, ECGs, using bipolar limb leads, were recorded during general anesthesia. The PR interval, representing AV transmission time was about 40 msec, which is quite long for hearts of this size. On the basis of detailed analysis of the data, we postulate the presence of a fixed delay or discontinuous propagation in the AV node not only in newborn mice, but in mammals of all sizes. CONCLUSION:AV transmission times obtained in mammals (including humans) cannot be explained on the basis of generally accepted, classic AV conduction theories. The acceptance of the presence of a fixed delay in the AV node may ultimately be of value to better understand AV node function during sinus rhythm and supraventricular arrhythmias.

authors

van der Tweel LH,Strackee J,Stokhof AA,Wassenaar C,Meijler FL

doi

10.1111/j.1540-8167.1999.tb00658.x

keywords:

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

168-73

issue

2

eissn

1045-3873

issn

1540-8167

journal_volume

10

pub_type

杂志文章
  • Substrate characterization and catheter ablation for monomorphic ventricular tachycardia in patients with apical hypertrophic cardiomyopathy.

    abstract:UNLABELLED:VT Ablation in Apical Hypertrophic Cardiomyopathy.  INTRODUCTION:Monomorphic ventricular tachycardia (VT) is uncommon in apical hypertrophic cardiomyopathy (HCM). The purpose of this study was to define the substrate and role of catheter ablation for VT in apical HCM. METHODS:Four patients with apical HCM ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2010.01875.x

    authors: Inada K,Seiler J,Roberts-Thomson KC,Steven D,Rosman J,John RM,Sobieszczyk P,Stevenson WG,Tedrow UB

    更新日期:2011-01-01 00:00:00

  • Signal-averaged isoharmonic body surface maps of patients with ischemic cardiomyopathy.

    abstract:INTRODUCTION:Prevention of sudden arrhythmic cardiac death depends on accurate identification of individuals at high risk. Previous studies of signals recorded directly from arrhythmogenic tissue suggested that the predictive value of the signal-averaged ECG could be enhanced by expanded temporal, spectral, and spatial...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1540-8167.2000.tb00315.x

    authors: Kavesh NG,Sarang SE,Gold MR

    更新日期:2000-02-01 00:00:00

  • Electrophysiological characteristics of the earliest activation site in idiopathic right ventricular outflow tract arrhythmias under mini-electrode mapping.

    abstract:INTRODUCTION:Right ventricular outflow tract ventricular arrhythmias (RVOT VAs) often originate in the voltage-transitional zone. The target electrogram could be compromised by the architecture of the roving catheter. Mini-electrodes could improve the mapping resolution, especially in low-voltage areas. The aim was to ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13856

    authors: Liu M,Jiang J,Su C,Li J,Chen X,Ma Y,Feng C,Liu J,Dong Y,Tang A,He J,Wang L

    更新日期:2019-05-01 00:00:00

  • Paradoxical undersensing during atrial flutter: what is the mechanism?

    abstract::A patient with congenital complete heart block underwent implantation of a dual-chamber pacemaker. He presented to the emergency room with fatigue and was found to be in atrial flutter. Device interrogation revealed undersensing of 5 mV flutter waves at a programmed sensitivity of 0.5 mV. Due to undersensing, mode swi...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2006.00571.x

    authors: Kalahasty G,Kenigsberg DN,Wood MA,Ellenbogen KA

    更新日期:2006-11-01 00:00:00

  • First interventional exchange of a left transvenous phrenic nerve stimulation lead from the novel remedē system.

    abstract::The remedē system is a novel fully implantable transvenous phrenic nerve stimulation (TPNS) device developed to treat central sleep apnea. No information is published on how to explant or replace its leads. An eighty-one year-old had a fractured lead and we removed it over a wire. However, unbreachable resistances occ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type:

    doi:10.1111/jce.14725

    authors: Gutleben KJ,Eitz T,Westlund R,Gummert JF,Sommer P,Fox H

    更新日期:2020-11-01 00:00:00

  • Catheter ablation of frequently recurring ventricular fibrillation in a patient after aortic valve repair.

    abstract::It has been demonstrated that idiopathic ventricular fibrillation (VF) can be triggered by ventricular premature beats (VPBs) arising from the Purkinje fibers. Eliminating these VPBs by radiofrequency catheter ablation prevented VF recurrences. Whether the same pathophysiology and the same treatment option exist in pa...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2004.03386.x

    authors: Li YG,Grönefeld G,Israel C,Hohnloser SH

    更新日期:2004-01-01 00:00:00

  • Rate-control drugs affect variability and irregularity measures of RR intervals in patients with permanent atrial fibrillation.

    abstract:INTRODUCTION:Irregularity measures have been suggested as risk indicators in patients with atrial fibrillation (AF); however, it is not known to what extent they are affected by commonly used rate-control drugs. We aimed at evaluating the effect of metoprolol, carvedilol, diltiazem, and verapamil on the variability and...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jce.12580

    authors: Corino VD,Ulimoen SR,Enger S,Mainardi LT,Tveit A,Platonov PG

    更新日期:2015-02-01 00:00:00

  • Catheter ablation of atrial arrhythmias in cardiac sarcoidosis.

    abstract:BACKGROUND:We previously reported on the incidence and clinical implications of supraventricular arrhythmia in patients with cardiac sarcoidosis (CS). The role of catheter ablation for the management of atrial arrhythmia (AA) in this patient population is unknown. METHODS AND RESULTS:One hundred consecutive patients w...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.12424

    authors: Willner JM,Viles-Gonzalez JF,Coffey JO,Morgenthau AS,Mehta D

    更新日期:2014-09-01 00:00:00

  • Correlative anatomy for the electrophysiologist, Part I: the pericardial space, oblique sinus, transverse sinus.

    abstract::There is an increasing need for invasive electrophysiologists to appreciate the exact anatomy of the epicardial space and the coronary veins. The location of the epicardial fat, the complementary relationship with the main cardiac veins, and the location of sensitive structures (arteries, phrenic nerve, esophagus) hav...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1540-8167.2010.01872.x

    authors: Lachman N,Syed FF,Habib A,Kapa S,Bisco SE,Venkatachalam KL,Asirvatham SJ

    更新日期:2010-12-01 00:00:00

  • Long-Term Results of Radiofrequency Hot Balloon Ablation in Patients With Paroxysmal Atrial Fibrillation: Safety and Rhythm Outcomes.

    abstract:INTRODUCTION:Isolation of pulmonary veins (PVs) and the posterior left atrium (LA) can be safely performed by radiofrequency hot balloon (RHB)-based box isolation. However, data on long-term effects for the treatment of atrial fibrillation (AF) by the use of this method remain limited. METHODS AND RESULTS:We treated 2...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.12820

    authors: Yamaguchi Y,Sohara H,Takeda H,Nakamura Y,Ihara M,Higuchi S,Satake S

    更新日期:2015-12-01 00:00:00

  • Approach to ablative management of patient with persistent atrial fibrillation and enduring pulmonary vein isolation.

    abstract::Enduring isolation of the pulmonary veins (PV) is becoming increasingly common in patients undergoing repeat catheter ablation for atrial fibrillation. We describe our approach to ablation strategy in a patient with enduring isolation of PV and briefly discuss the role of non-PV triggers. ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/jce.14464

    authors: Kalman JM,Sugumar H

    更新日期:2020-07-01 00:00:00

  • Comparison of atrial arrhythmia recurrence after persistent atrial fibrillation ablation between patients with or without tachycardia-induced cardiomyopathy.

    abstract:BACKGROUND:The presence of heart failure (HF) has been associated with poorer outcomes in patients undergoing catheter ablation (CA) for atrial fibrillation (AF). However, the effectiveness of CA amongst the subset of patients with tachycardia-induced cardiomyopathy (TIC) remains poorly defined. METHODS AND RESULTS:In...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14144

    authors: Yamashita S,Tokuda M,Matsuo S,Mahida S,Hachisuka EO,Sato H,Ikewaki H,Oseto H,Yokoyama M,Isogai R,Tokutake K,Yokoyama K,Narui R,Kato M,Tanigawa S,Sugimoto K,Yoshimura M,Yamane T

    更新日期:2019-11-01 00:00:00

  • Chronic amiodarone reduces transmural dispersion of repolarization in the canine heart.

    abstract:INTRODUCTION:Amiodarone is a potent antiarrhythmic agent used in the management of both atrial and ventricular arrhythmias. In addition to its beta-blocking properties, amiodarone is known to block the sodium, potassium, and calcium channels in the heart. Its complex electropharmacology notwithstanding, the reasons for...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.1997.tb01018.x

    authors: Sicouri S,Moro S,Litovsky S,Elizari MV,Antzelevitch C

    更新日期:1997-11-01 00:00:00

  • Impact of myocardial viability and left ventricular lead location on clinical outcome in cardiac resynchronization therapy recipients with ischemic cardiomyopathy.

    abstract:INTRODUCTION:Cardiac resynchronization therapy (CRT) recipients with ischemic cardiomyopathy (ICM) have scar segments that may limit ventricular resynchronization and clinical response. The impact of myocardial viability at the left ventricular (LV) pacing site on CRT response is poorly elucidated. METHODS AND RESULTS...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.12348

    authors: Bose A,Kandala J,Upadhyay GA,Riedl L,Ahmado I,Padmanabhan R,Gewirtz H,Mulligan LJ,Singh JP

    更新日期:2014-05-01 00:00:00

  • Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging.

    abstract:INTRODUCTION:Radiofrequency (RF) and cryoablation are routinely used to treat arrhythmias, but the extent and time course of edema associated with the two different modalities is unknown. Our goal was to follow the lesion maturation and edema formation after RF and cryoablation using serial magnetic resonance imaging (...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13785

    authors: Yamashita K,Kholmovski E,Ghafoori E,Kamali R,Kwan E,Lichter J,MacLeod R,Dosdall DJ,Ranjan R

    更新日期:2019-02-01 00:00:00

  • Recent history of vasovagal syncope in a young, referral-based population is a stronger predictor of recurrent syncope than lifetime syncope burden.

    abstract:INTRODUCTION:accurate selection of patients for vasovagal syncope studies requires strong risk stratification and knowledge of the natural history of syncope. We aimed to test the hypothesis that recent history of vasovagal syncope compared to distant history better predicts subsequent recurrence of syncope. METHODS A...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1540-8167.2010.01848.x

    authors: Sumner GL,Rose MS,Koshman ML,Ritchie D,Sheldon RS,Prevention of Syncope Trial Investigators.

    更新日期:2010-12-01 00:00:00

  • Safety and feasibility of percutaneous skin closure using purse-string suture compared with compression bandage after pulmonary vein isolation.

    abstract:INTRODUCTION:This observational study was designed to analyze the safety and feasibility of percutaneous skin closure using a purse-string suture and compare it with the use of a compression bandage after pulmonary vein isolation. METHODS AND RESULTS:A total of 407 patients undergoing pulmonary vein isolation (217 wit...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13271

    authors: Akkaya E,Berkowitsch A,Zaltsberg S,Deubner N,Greiss H,Hain A,Hamm CW,Sperzel J,Neumann T,Kuniss M

    更新日期:2017-09-01 00:00:00

  • Congenital disorders of cardiac rhythm and conduction.

    abstract::Electrical instability of the heart has numerous congenital origins. This review approaches the problems from a morphological standpoint, utilizing selected examples from my own studies of the human cardiac conduction system performed during the last three decades. Subjects discussed include multifocal Purkinje cell t...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1540-8167.1993.tb01256.x

    authors: James TN

    更新日期:1993-12-01 00:00:00

  • Acute atrial dilatation slows conduction and increases AF vulnerability in the human atrium.

    abstract:INTRODUCTION:The mechanisms by which atrial stretch favors the development of a substrate for atrial fibrillation (AF) are not fully understood. In this study, the role of stretch-induced conduction changes in the creation of a proarrhythmic substrate has been investigated by quantifying the spatial distribution of loc...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2010.01939.x

    authors: Ravelli F,Masè M,del Greco M,Marini M,Disertori M

    更新日期:2011-04-01 00:00:00

  • Left atrial fibrillation with regular right atrial activation and a single left-to-right electrical interatrial connection: multisite mapping of dissimilar atrial rhythms.

    abstract::We report two patients who had isolated atrial fibrillation in the left atrium and regular activation of the entire right atrium. Mapping of the arrhythmia was performed using a 64-electrode basket catheter that was inserted intravenously and deployed in the right and left atria. Both patients manifested a single, sta...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2000.tb00014.x

    authors: Ndrepepa G,Zrenner B,Schreieck J,Karch MR,Schneider MA,Schömig A,Schmitt C

    更新日期:2000-05-01 00:00:00

  • Atrial fibrosis in non-atrial fibrillation individuals and prediction of atrial fibrillation by use of late gadolinium enhancement magnetic resonance imaging.

    abstract:INTRODUCTION:Besides the traditional concept of atrial fibrillation (AF) perpetuating atrial structural remodeling, there is increasing evidence that atrial fibrosis might precede AF, highlighting the need for better characterization of the fibrotic substrate. We aimed to assess atrial fibrosis by use of late gadoliniu...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13846

    authors: Siebermair J,Suksaranjit P,McGann CJ,Peterson KA,Kheirkhahan M,Baher AA,Damal K,Wakili R,Marrouche NF,Wilson BD

    更新日期:2019-04-01 00:00:00

  • Differential effect of beta-adrenergic stimulation on the frequency-dependent electrophysiologic actions of the new class III antiarrhythmics dofetilide, ambasilide, and chromanol 293B.

    abstract:INTRODUCTION:Blockade of the rapid delayed rectifier potassium current (IKr) as an important mechanism for current Class III antiarrhythmics is less effective in action potential prolongation during beta-adrenergic activation. We hypothesized that blockade of the increased slow IK (IKs) current during beta-adrenergic s...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.1997.tb01039.x

    authors: Schreieck J,Wang Y,Gjini V,Korth M,Zrenner B,Schömig A,Schmitt C

    更新日期:1997-12-01 00:00:00

  • Role of streptomycin-sensitive stretch-activated channel in chest wall impact induced sudden death (commotio cordis).

    abstract:INTRODUCTION:Deaths secondary to low-energy impacts to the precordium in young individuals (commotio cordis) have been reported with increasing frequency. In a swine model, baseball impacts induce ventricular fibrillation when directed at the center of the left ventricle during the vulnerable portion of repolarization ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2005.40664.x

    authors: Garan AR,Maron BJ,Wang PJ,Estes NA 3rd,Link MS

    更新日期:2005-04-01 00:00:00

  • Importance of catheter contact force during irrigated radiofrequency ablation: evaluation in a porcine ex vivo model using a force-sensing catheter.

    abstract:INTRODUCTION:Ablation electrode-tissue contact has been shown to be an important determinant of lesion size and safety during nonirrigated ablation but little data are available during irrigated ablation. We aimed to determine the importance of contact force during irrigated-tip ablation. METHODS AND RESULTS:Freshly e...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2009.01693.x

    authors: Thiagalingam A,D'Avila A,Foley L,Guerrero JL,Lambert H,Leo G,Ruskin JN,Reddy VY

    更新日期:2010-07-01 00:00:00

  • Reduction of the internal atrial defibrillation threshold with balanced orthogonal sequential shocks.

    abstract:INTRODUCTION:The aim of this study was to determine the atrial defibrillation threshold (ADFT) of a first shock across the standard right atrium (RA) to distal coronary sinus (dCS) configuration followed by a second shock along the atrial septum with a standard sequential waveform (the second shock leading edge equaled...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2002.00904.x

    authors: Zheng X,Benser ME,Walcott GP,Smith WM,Ideker RE

    更新日期:2002-09-01 00:00:00

  • Avoid delivering therapies for nonsustained fast ventricular tachyarrhythmia in patients with implantable cardioverter/defibrillator: the ADVANCE III Trial.

    abstract:INTRODUCTION:The purpose of this investigation is to evaluate whether a prolonged detection interval for life threatening ventricular tachyarrhythmia (VT) is able to reduce therapies (Rx) delivered by an implantable cardioverter/defibrillator (ICD). Until now, only the PREPARE trial demonstrated a reduction of ICD Rx i...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1540-8167.2008.01415.x

    authors: Schwab JO,Gasparini M,Lunati M,Proclemer A,Kaup B,Santi E,Ligorio G,Klersy C,DE Sousa J,Okreglicki A,Arenal A,Wijffels M,Lemke B

    更新日期:2009-06-01 00:00:00

  • Autonomic dysfunction and new-onset atrial fibrillation in patients with left ventricular systolic dysfunction after acute myocardial infarction: a CARISMA substudy.

    abstract:BACKGROUND:Atrial fibrillation (AF) increases morbidity and mortality in patients with previous myocardial infarction and left ventricular systolic dysfunction. The purpose of this study was to identify patients with a high risk for new-onset AF in this population using invasive and noninvasive electrophysiological tes...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2010.01795.x

    authors: Jons C,Raatikainen P,Gang UJ,Huikuri HV,Joergensen RM,Johannesen A,Dixen U,Messier M,McNitt S,Thomsen PE,Cardiac Arrhythmias and Risk Stratification after Acute Myocardial Infarction (CARISMA) Study Group.

    更新日期:2010-09-01 00:00:00

  • Incidence of asymptomatic cerebral microthromboembolism after atrial fibrillation ablation guided by complex fractionated atrial electrogram.

    abstract:BACKGROUND:The incidence of cerebral thromboembolism after pulmonary vein isolation (PVI) ranges from 2% to 14%. This study investigated the incidence of cerebral thromboembolism after complex fractionated atrial electrogram (CFAE) ablation with or without PVI. METHODS:One hundred consecutive atrial fibrillation (AF) ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2011.02259.x

    authors: Ichiki H,Oketani N,Ishida S,Iriki Y,Okui H,Maenosono R,Ninomiya Y,Matsushita T,Miyata M,Hamasaki S,Tei C

    更新日期:2012-06-01 00:00:00

  • Ibutilide-induced cardioversion of atrial fibrillation during pregnancy.

    abstract::We present two cases of successful cardioversion of atrial fibrillation using intravenous ibutilide during pregnancy. One patient had atrial fibrillation, complicating the Wolff-Parkinson-White syndrome and the other had a history of nonobstructive hypertrophic cardiomyopathy. No adverse maternal or fetal effects were...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2006.00752.x

    authors: Kockova R,Kocka V,Kiernan T,Fahy GJ

    更新日期:2007-05-01 00:00:00

  • Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations.

    abstract:INTRODUCTION:Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II-receptor blockers (ARBs) are prototypes of "upstream" therapy for the management of atrial fibrillation (AF). Ectopic activity arising from the PV sleeves plays a prominent role in the development of AF. METHODS:Transmembrane action potenti...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2010.01972.x

    authors: Sicouri S,Cordeiro JM,Talarico M,Antzelevitch C

    更新日期:2011-06-01 00:00:00