Abstract：
OBJECTIVES:This study was undertaken to assess the value of Cockroft-Gault Formula (FCG) in the patients of an Internal Medicine ward. METHODS:FCG was compared with creatinine clearance (DC) adjusted for corporal area. Serum creatinine was measured after 24 h urine collection and 8 h fast. By the subtraction of FCG from DC, the variable difference (DIF) was calculated. FCG was calculated using total body weight (PT) and lean body weight (PS). All patients were included unless they had renal failure. RESULTS:Renal function was calculated in 92 patients, 33 women and 59 men. Mean age was 60.8 +/- 17.9 (13-87). Mean FCG (64.7 +/- 27.4) and mean DC (68.4 +/- 32.6) were not significantly different and a correlation between them was found (r = 0.68; p < 0.001). Using PS to estimate FCG the correlation coefficient was increased to 0.75 (p < 0.001). DC and FCG using PT or PS correlated inversely with age (r = 0.59; r = 0.53; r = 0.66, respectively; p < 00.1). In a cluster analysis model we could find that for extremes of renal function FCG overestimated (DIF = -10.4 +/- 13.3) or underestimated (DIF = 29.8 +/- 29.7) DC. The main influence for the difference between the two methods was body weight (r = -0.69; p < 0.001). The distribution by diagnosis led to two classes of patients for whom DIF was significantly different (p < 0.02), and body weight was the main factor. CONCLUSION:Cockroft-Gault formula, although correlating with creatinine clearance, over or underestimates creatinine clearance for extremes of renal function. Age and body weight were the main factors for the differences found between the two methods.
journal_name
Acta Med Portjournal_title
Acta medica portuguesaauthors
Alcântara P,Gonçalves F,Moreira C,Gonzalez MAsubject
Has Abstractpub_date
1998-08-01 00:00:00pages
767-72issue
8-9eissn
0870-399Xissn
1646-0758journal_volume
11pub_type
杂志文章abstract：:Among others complications due central venous catheters (CVCs), the blood infection (BI) deserves particular attention. The purposes of this study were to analyze the clinical and epidemiological characteristics of adult patients using CVC; to know the yeast colonization index; and to link it to risk factors for BI. Y...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:Allergic diseases are a major public health problem. It is essential to develop prevention strategies applied to it. A number of risk factors have been identified, but some are still under contradictory. Changing the dietary pattern of the at-risk infant may prevent food allergy. Evidence suggests that exclusive breas...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2007-05-01 00:00:00
abstract：:In the Portuguese National Health Service, little attention has been paid to oral health care. The almost nonexistence of a dentistry network raises concern about accessibility to services, and justifies the need to call on a predominantly private provision of services. The coexistence between the public and private s...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.11964
更新日期：2019-06-28 00:00:00
abstract：:Despite the recent advances in the development of complementary diagnostic exams and modern targeted therapies, colorectal cancer remains a major cause of morbidity and mortality worldwide. In this context, a lot of research has been conducted in the last years to find new markers of poor prognosis. The existence of a...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：10.20344/amp.5398
更新日期：2015-05-01 00:00:00
abstract：INTRODUCTION:Biological and biosimilar medicinal products have specific characteristics that call for a closer monitoring of their safety profile. Since the current legal framework stems from both European and national regulations, some gaps in the operational field may be expected. The goal of this paper is to identif...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.8079
更新日期：2017-03-31 00:00:00
abstract：INTRODUCTION:Portugal is experiencing the effects of the COVID-19 pandemic since March 2020. All-causes mortality in Portugal increased during March and April 2020 compared to previous years, but this increase is not explained by COVID-19 reported deaths. The aim of this study was to analyze and consider other criteria...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.13928
更新日期：2020-06-01 00:00:00
abstract：INTRODUCTION:The purpose of this study was to provide objective and real-life data concerning the impact of the COVID-19 pandemicon ophthalmology residency training in Portugal. MATERIAL AND METHODS:Descriptive survey-based study applied to current Portuguese ophthalmology residents (n = 80 eligible). RESULTS:Seventy...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.14341
更新日期：2020-10-01 00:00:00
abstract：:In spite of all the efforts that has been made in prevention and the success of antiretroviral therapy (ART), AIDS remains a serious public health problem. So, there is a need for development of new antiretrovirals (ARVs) and new therapeutic strategies. New ARVs are currently on advanced stages of clinical evaluati...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2012-05-01 00:00:00
abstract：:We report a case of a 25-year-old women admitted to the emergency room of Santa Maria Hospital with pancytopenia and fever. We describe the diagnostic work-up, laboratory findings, therapy, outcome and follow-up after discharge Lastly, we discuss aplastic anemia as a rare systemic lupus erythematosus complication, wit...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The authors present a case of a 60-year-old male patient, previously diagnosed with B-cell chronic lymphocytic leukemia, who was admitted to the Emergency Room with dyspnea. The initial evaluation revealed severe anemia (Hgb = 5.0 g/dL) with hyperleukocytosis (800.000/µL), nearly all of the cells being mature lymphocy...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2016-05-01 00:00:00
abstract：INTRODUCTION:Since dysphagia may be one of the brain post-stroke consequences, the objective of this study was to analyze the average recovery time of patients with cerebrovascular accident and dysphagia subjected to speech therapy in a hospital bed. MATERIAL AND METHODS:Systematic review performed following the 'Pref...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：10.20344/amp.9183
更新日期：2017-12-29 00:00:00
abstract：:In the medical press there are several data confirming the value of E.R.C.P. and E.E.S., in the therapeutical approach of acute lithiasic pancreatitis (A.L.P.). Nowadays it is a first line endoscopic technic on the therapeutical approach in A.L.P. permitting to clean out the biliary tree of stones, eliminating the eti...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：INTRODUCTION:To evaluate the safety and impact on visual acuity, retinal and choroidal morphology of simultaneous cataract surgery and intravitreal anti-vascular endothelial growth factor on patients with visually significant cataracts and previously treated exudative age-related macular degeneration. MATERIAL AND MET...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.7850
更新日期：2017-02-27 00:00:00
abstract：:The effects of immunodepression on several disease states have constituted an important area of research, leading to the identification of relevant associations between immunodepression and a vast set of comorbidities, including infectious diseases, cardiovascular diseases and cancer. Research on the effects of immuno...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：10.20344/amp.7997
更新日期：2017-01-31 00:00:00
abstract：:Sympathetic and parasympathetic nervous system evaluation was performed in 21 patients with rheumatoid arthritis. Every patient had autonomic nervous system (ANS) dysfunction, the parasympathetic involvement being the most frequent. ANS dysfunction may explain some manifestations and may well be the expression of a la...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:Rhabdomyolysis is a common entity that often has a multifactorial etiology. It usually affects healthy individuals, following trauma, excessive physical activity, convulsive crisis, alcohol and other drugs consumption or infections. Accumulation of intracellular calcium, activation of proteases and lipases, production...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2005-07-01 00:00:00
abstract：:Nowadays, prostate cancer is very frequent in men. The evolution of the possibilities of early diagnosis and the results obtained with radical therapeutics have brought this pathology to our attention. The physicians involved, either general practitioners or specialists in internal medicine or urology, must pay maximu...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：INTRODUCTION:The growing concern surrounding health safety issues makes it essential that everyone, in particular the elderly due to their commonly prescribed multiple drugs, has a complete and up to date list of prescriptions. We planned to assess the quality of the electronic records of prolonged medication. MATERIA...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,多中心研究
doi：
更新日期：2014-09-01 00:00:00
abstract：:Several infectious, neoplastic or inflammatory skin diseases, may be early manifestations of HIV infection. We reviewed the clinical data of 226 HIV seropositive male patients with cutaneous disease, from a total of 337 inpatients at the Infectious Diseases Unit--Department of Medicine 1--Curry Cabral Hospital, from 1...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：INTRODUCTION:The Exercise Self-Efficacy scale (ESES) is a reliable measure, in the English language, of exercise self-efficacy in individuals with spinal cord injury. The aim of this study was to culturally adjust and validate the Exercise Self-Efficacy scale in the Portuguese language. MATERIAL AND METHODS:The Exerci...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.8884
更新日期：2017-11-29 00:00:00
abstract：INTRODUCTION:Creatine deficiency syndromes are a recently described group of diseases characterized by inborn errors of creatine metabolism. Clinical features include a spectrum of neurodevelopment disorders of diverse severity. They are characterized by low levels of cerebral creatine caused by different pathogenic mu...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2012-11-01 00:00:00
abstract：INTRODUCTION:Perfectionism and intolerance to frustration are the main factors of vulnerability to psychological stress observed in students of the Integrated Master Degree in Medicine of the Faculty of Medicine, University of Coimbra, a study claims. We aimed to ascertain their reasons, seeking for their prevention. ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.9976
更新日期：2018-10-31 00:00:00
abstract：:Gastrointestinal Bleeding (GIB) is a complication in patients with Chronic Renal Failure (CRF) on regular hemodialysis (HD). To analyse the importance of GIB we studied, retrospectively, the causes of hospitalization in 301 patients, all on HD in the same Unit in January 1990. The average age was 57.4 +/- 14.2 years (...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:New generation oral anticoagulants - rivaroxaban, apixaban and edoxaban - represent an important medical achievement. Their therapeutic effectiveness and ease of use make them essential in the management of thromboembolic conditions. However, as warfarin, they have known haemorrhagic risks. This paper reports the case...
journal_title：Acta medica portuguesa
pub_type：
doi：10.20344/amp.9397
更新日期：2019-06-28 00:00:00
abstract：:A retrospective epidemiological study was made based on 1,768 burn patients admitted either to the Burns Unit or the general wards of the Plastic Surgery Department of Prelada Hospital in Oporto, from October 1988 until November 1997, corresponding to almost 8.5% of the overall patients admitted. The average age of th...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：BACKGROUND:Some families fulfilling the Amsterdam Criteria (AC) differ from the Lynch syndrome (LS) in that colorectal cancers (CRC) do not present microsatellite instability (MSI) and DNA mismatch repair gene mutations are not found. These families have been designated as Familial Colorectal Cancer type X (XS) and the...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：INTRODUCTION/OBJECTIVES:The authors make the balance of the first five years of teaching Anatomy to the Licensure in Health Sciences, of Lisbon University. MATERIALS AND METHODS:Were studied 408 students, enrolled in the Curricular Unit of Anatomy (mandatory subject of the 1st semester) and 29 in the Curricular Unit o...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2013-05-01 00:00:00
abstract：:Essencial Thrombocytemia is a rare chronic myeloproliferative disease of unknown etiology, characterized by markedly elevated platelet production (> 600,000/ml). It is more frequent among women above 50 years of age and may be associated with hemorrhagic or thrombotic tendencies. The authors report a case of Essencial...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:The accurate treatment of a dyslipidaemia is based on correct diagnosis. Together with the laboratory values. A good clinical interview, focusing on the family history, is the bases for a good diagnosis strategy. The author schematze the rules of etiological diagnosis of inherited defects of lipid metabolism. ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：INTRODUCTION:The burn injury probably represents the largest stimulus for muscle protein catabolism. This state is characterized by an accelerated catabolism of the lean or skeletal mass that results in a clinical negative balance of nitrogen and muscle wasting. The determination of an appropriate value for protein int...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
